6,99 % | The Vanguard Group, Inc. | 8.710.158 | -109.771 | 31.12.2023 |
6,66 % | Avidity Partners Management LP | 8.298.570 | 0 | 31.12.2023 |
6,54 % | BlackRock Institutional Trust Company, N.A. | 8.157.094 | -580.111 | 31.12.2023 |
4,09 % | Palo Alto Investors LP | 5.102.193 | -573.683 | 31.12.2023 |
3,53 % | Chione, Ltd. | 4.400.000 | -600.000 | 31.12.2022 |
2,49 % | Citadel Advisors LLC | 3.101.399 | -2.489 | 31.12.2023 |
1,91 % | Geode Capital Management, L.L.C. | 2.382.428 | 95.282 | 31.12.2023 |
1,88 % | GSA Capital Partners LLP | 2.337.985 | 1.769.687 | 31.12.2023 |
1,65 % | State Street Global Advisors (US) | 2.053.773 | 10.768 | 31.12.2023 |
1,58 % | Renaissance Technologies LLC | 1.964.377 | 1.233.977 | 31.12.2023 |
1,55 % | Marshall Wace LLP | 1.926.782 | -256.419 | 31.12.2023 |
1,42 % | BNP Paribas Securities Corp. North America | 1.769.184 | 108.286 | 31.12.2023 |
1,38 % | Delphi Ventures L.P. | 1.724.222 | 0 | 29.3.2024 |
1,33 % | Adage Capital Management, L.P. | 1.663.300 | 1.663.300 | 31.12.2023 |
1,23 % | Millennium Management LLC | 1.534.264 | 416.356 | 31.12.2023 |
1,20 % | C WorldWide Asset Management Fondsmaeglerselskab A/S | 1.500.000 | 0 | 31.12.2023 |
1,04 % | BlackRock Financial Management, Inc. | 1.295.105 | -180.263 | 31.12.2023 |
0,97 % | Goldman Sachs & Company, Inc. | 1.210.975 | -542.212 | 31.12.2023 |
0,90 % | AlphaCentric Advisors LLC. | 1.125.000 | 0 | 31.12.2023 |
0,90 % | LifeSci Fund Management LLC | 1.125.000 | 0 | 31.12.2023 |
0,89 % | J.P. Morgan Securities LLC | 1.107.708 | 44.994 | 31.12.2023 |
0,83 % | Tejara Capital Ltd. | 1.031.348 | -46.040 | 31.12.2023 |
0,80 % | Parkwood LLC | 1.000.000 | 1.000.000 | 30.9.2023 |
0,78 % | Barclays Bank PLC | 970.058 | -182.240 | 31.12.2023 |
0,73 % | Northern Trust Investments, Inc. | 915.422 | 28.968 | 31.12.2023 |
0,64 % | UBS O'Connor LLC | 802.327 | -74.383 | 31.12.2023 |
0,59 % | Altium Capital Management LP | 740.000 | 0 | 31.12.2023 |
0,57 % | DWS Investment S.A. | 712.696 | 712.696 | 31.12.2023 |
0,55 % | Morgan Stanley & Co. LLC | 688.558 | -181.606 | 31.12.2023 |
0,50 % | D. E. Shaw & Co., L.P. | 617.216 | -5.639 | 31.12.2023 |
0,49 % | DWS Investments UK Limited | 611.116 | 556.081 | 31.12.2023 |
0,48 % | AQR Capital Management, LLC | 598.142 | 96.343 | 31.12.2023 |
0,45 % | SilverArc Capital Management, LLC | 561.955 | 0 | 31.12.2023 |
0,43 % | Candriam Belgium S.A. | 530.694 | -610.000 | 31.12.2023 |
0,39 % | Lombard Odier Asset Management (Europe) Ltd | 484.750 | -18.519 | 30.9.2022 |
0,38 % | Birchview Capital, LP | 469.832 | -102.000 | 31.12.2023 |
0,37 % | UBS Financial Services, Inc. | 457.185 | -449.460 | 31.12.2023 |
0,36 % | Nuveen LLC | 452.406 | 0 | 31.12.2023 |
0,32 % | Ikarian Capital LLC | 400.000 | 0 | 31.12.2023 |
0,31 % | Los Angeles Capital Management LLC | 387.520 | -4.020 | 31.3.2024 |
0,30 % | Macquarie Investment Management | 380.000 | 0 | 31.12.2023 |
0,27 % | BlackRock Investment Management, LLC | 335.319 | 0 | 31.12.2023 |
0,25 % | Columbia Threadneedle Investments (US) | 309.967 | -47.011 | 31.12.2023 |
0,25 % | Charles Schwab Investment Management, Inc. | 309.909 | 51.000 | 31.12.2023 |
0,25 % | Paulson (Richard A.) | 308.799 | -3.563 | 4.4.2024 |
0,25 % | BofA Global Research (US) | 306.455 | -46.167 | 31.12.2023 |
0,23 % | Bridgeway Capital Management, LLC | 289.500 | 0 | 31.12.2023 |
0,23 % | Jacobs Levy Equity Management, Inc. | 284.457 | -2.127.871 | 31.12.2023 |
0,22 % | BlackRock Asset Management Ireland Limited | 279.048 | -82.390 | 31.12.2023 |
0,22 % | Jane Street Capital, L.L.C. | 275.460 | 275.460 | 31.12.2023 |
0,22 % | BNY Mellon Asset Management | 275.198 | -156.448 | 31.12.2023 |
0,22 % | Acadian Asset Management LLC | 275.059 | 275.059 | 31.12.2023 |
0,22 % | Fidelity Management & Research Company LLC | 268.286 | 1.839 | 31.12.2023 |
0,20 % | BlackRock Advisors (UK) Limited | 246.479 | -13.680 | 31.3.2024 |
0,18 % | PanAgora Asset Management Inc. | 227.445 | 227.445 | 31.12.2023 |
0,18 % | Two Sigma Investments, LP | 225.060 | 189.860 | 31.12.2023 |
0,17 % | Atom Investors LP | 216.690 | 25.865 | 31.12.2023 |
0,17 % | Exchange Traded Concepts, LLC | 212.638 | 96.774 | 31.3.2024 |
0,15 % | AllianceBernstein L.P. | 192.810 | 0 | 31.12.2023 |
0,15 % | Dafna Capital Management, LLC | 192.678 | 0 | 31.12.2023 |
0,12 % | Newton Investment Management North America, LLC | 155.120 | 0 | 31.12.2023 |
0,12 % | Morgan Stanley Smith Barney LLC | 150.099 | -10.257 | 31.12.2023 |
0,11 % | Mano (Michael) | 140.602 | -3.576 | 1.3.2024 |
0,11 % | Rhumbline Advisers Ltd. Partnership | 138.107 | -50 | 31.12.2023 |
0,11 % | Monashee Investment Management, LLC | 132.435 | 132.435 | 31.12.2023 |
0,10 % | Mitchener (Stephen) | 121.366 | -6.357 | 1.3.2023 |
0,09 % | Woodline Partners LP | 116.718 | -17.394 | 31.12.2023 |
0,07 % | LSV Asset Management | 90.760 | 0 | 31.3.2024 |
0,07 % | SEI Investments Management Corporation | 90.160 | -4.020 | 31.3.2024 |
0,07 % | T. Rowe Price International Ltd | 87.113 | 0 | 31.12.2023 |
0,07 % | Goldman Sachs Asset Management, L.P. | 85.618 | -76.242 | 31.12.2023 |
0,07 % | Boothbay Fund Management, LLC | 81.736 | 0 | 31.12.2023 |
0,06 % | Northern Trust Global Investments | 80.725 | -18.553 | 31.12.2023 |
0,06 % | Mason (Michael P) | 79.865 | -110.622 | 29.3.2024 |
0,06 % | Susquehanna International Group, LLP | 78.596 | -59.213 | 31.12.2023 |
0,06 % | SG Americas Securities, L.L.C. | 73.430 | 54.839 | 31.12.2023 |
0,06 % | JPMorgan Private Bank (United States) | 73.412 | 68.412 | 31.12.2023 |
0,06 % | Connor, Clark & Lunn Investment Management Ltd. | 71.224 | 35.945 | 31.12.2023 |
0,06 % | Cheng (Sohanya Roshan) | 70.884 | -125.085 | 29.3.2024 |
0,05 % | Mellon Investments Corporation | 66.884 | 0 | 31.12.2023 |
0,05 % | Vident Investment Advisory, LLC | 66.422 | 66.422 | 30.6.2023 |
0,05 % | SunAmerica Asset Management, LLC | 56.295 | -228 | 31.12.2023 |
0,04 % | Rangwala (Reshma) | 51.595 | -304.094 | 29.3.2024 |
0,04 % | XTX Markets LLC | 49.122 | -260.943 | 31.12.2023 |
0,04 % | Voya Investment Management LLC | 45.471 | 0 | 31.12.2023 |
0,04 % | HSBC Global Asset Management (UK) Limited | 45.290 | 362 | 31.12.2023 |
0,04 % | Bohlin (Garen G.) | 45.140 | 0 | 29.3.2024 |
0,04 % | G.W. & Wade, LLC. | 45.140 | 0 | 31.12.2023 |
0,03 % | RBC Capital Markets Wealth Management | 41.756 | -20.844 | 31.12.2023 |
0,03 % | T. Rowe Price Associates, Inc. | 40.572 | 3.700 | 29.2.2024 |
0,03 % | LUNIS Vermögensmanagement AG | 38.000 | 0 | 31.12.2023 |
0,03 % | Bleakley Financial Group LLC | 37.938 | 37.938 | 31.12.2023 |
0,03 % | Sawtooth Asset Management, Inc. | 37.938 | 37.938 | 31.12.2023 |
0,03 % | Poulton (Stuart) | 36.723 | -145.193 | 29.3.2024 |
0,03 % | Kennedy Investment Group | 35.000 | 0 | 31.12.2023 |
0,03 % | Principal Global Investors (Equity) | 31.442 | -1.396 | 31.12.2023 |
0,02 % | Group One Trading, L.P. | 30.473 | -24.040 | 31.12.2023 |
0,02 % | Redwood Wealth Management Group, LLC | 29.730 | -3.000 | 31.12.2023 |
0,02 % | Florida State Board of Administration | 29.422 | 29.422 | 31.12.2023 |
0,02 % | Wells Fargo Bank, N.A. | 29.351 | 6.682 | 31.12.2023 |