9,86 % | Fidelity Management & Research Company LLC | 11.598.839 | 1.121.528 | 31.12.2023 |
9,35 % | The Vanguard Group, Inc. | 10.997.974 | 273.565 | 31.12.2023 |
5,51 % | Wellington Management Company, LLP | 6.488.500 | -1.497.856 | 31.12.2023 |
5,01 % | State Street Global Advisors (US) | 5.893.358 | 618.872 | 31.12.2023 |
2,71 % | T. Rowe Price Associates, Inc. | 3.192.799 | 2.233.450 | 31.12.2023 |
2,18 % | Janus Henderson Investors | 2.568.405 | 75.079 | 31.12.2023 |
2,15 % | RTW Investments L.P. | 2.525.080 | -49.118 | 31.12.2023 |
12,63 % | BlackRock Institutional Trust Company, N.A. | 14.854.640 | 661.991 | 31.12.2023 |
1,89 % | T. Rowe Price Investment Management, Inc. | 2.229.485 | 413.299 | 31.12.2023 |
1,78 % | Boxer Capital, L.L.C. | 2.100.000 | 0 | 31.12.2023 |
1,78 % | Geode Capital Management, L.L.C. | 2.090.125 | 111.760 | 31.12.2023 |
1,72 % | Morgan Stanley & Co. LLC | 2.025.789 | 1.320.687 | 31.12.2023 |
1,49 % | PFM Health Sciences, LP | 1.757.192 | -642.353 | 31.12.2023 |
1,38 % | Logos Global Management LLC | 1.625.000 | 375.000 | 31.12.2023 |
1,37 % | Lord, Abbett & Co. LLC | 1.607.812 | 1.006.641 | 31.12.2023 |
1,20 % | Polar Capital LLP | 1.417.054 | -1.237.391 | 31.12.2023 |
1,20 % | Fidelity Institutional Asset Management | 1.408.944 | -104.569 | 31.12.2023 |
1,17 % | Pictet Asset Management Ltd. | 1.372.244 | -875.199 | 31.12.2023 |
1,03 % | Invus Public Equities Advisors, LLC | 1.214.284 | -304.547 | 31.12.2023 |
1,02 % | Millennium Management LLC | 1.199.341 | 499.555 | 31.12.2023 |
0,92 % | Farallon Capital Management, L.L.C. | 1.087.772 | 1.066.000 | 31.12.2023 |
0,90 % | Invesco Advisers, Inc. | 1.053.877 | 120.099 | 31.12.2023 |
0,82 % | American Century Investment Management, Inc. | 967.000 | -1.258.762 | 31.12.2023 |
0,75 % | Northern Trust Investments, Inc. | 881.216 | 24.780 | 31.12.2023 |
0,69 % | First Turn Management, LLC | 807.444 | 807.444 | 31.12.2023 |
0,67 % | Charles Schwab Investment Management, Inc. | 789.969 | 33.257 | 31.12.2023 |
0,64 % | Mellon Investments Corporation | 756.882 | -39.906 | 31.12.2023 |
0,61 % | Norges Bank Investment Management (NBIM) | 722.229 | -117.127 | 31.12.2023 |
0,55 % | Fidelity Investments Canada ULC | 652.779 | -70.018 | 31.12.2023 |
0,55 % | Franklin Advisers, Inc. | 651.266 | -471.084 | 31.12.2023 |
0,54 % | Susquehanna International Group, LLP | 635.502 | 470.916 | 31.12.2023 |
0,53 % | Marshall Wace LLP | 626.087 | -907.882 | 31.12.2023 |
0,52 % | Goldman Sachs & Company, Inc. | 616.782 | 77.971 | 31.12.2023 |
0,51 % | Darwin Global Management Ltd | 600.000 | 600.000 | 31.12.2023 |
0,48 % | Hood River Capital Management LLC | 560.981 | 58.455 | 31.12.2023 |
0,47 % | Eventide Asset Management, LLC | 556.000 | 0 | 31.12.2023 |
0,47 % | Assenagon Asset Management S.A. | 554.658 | 554.658 | 31.12.2023 |
0,46 % | Fisher Investments | 536.046 | 536.046 | 31.12.2023 |
0,44 % | Principal Global Investors (Equity) | 521.172 | -4.111 | 31.12.2023 |
0,42 % | Great Point Partners, LLC | 500.000 | -100.000 | 31.12.2023 |
0,40 % | Candriam Luxembourg S.A. | 468.029 | 6.000 | 29.2.2024 |
0,38 % | Saturn V Capital Management LLC | 448.144 | -47.024 | 31.12.2023 |
0,37 % | Finepoint Capital LP | 431.693 | 0 | 31.12.2023 |
0,37 % | BNP Paribas Asset Management USA, Inc. | 430.891 | -141.505 | 31.12.2023 |
0,36 % | Ensign Peak Advisors, Inc. | 425.863 | 0 | 31.12.2023 |
0,36 % | Caption Management, LLC | 420.359 | 405.284 | 31.12.2023 |
0,36 % | BlackRock Financial Management, Inc. | 418.028 | -192.885 | 31.12.2023 |
0,35 % | Sofinnova Investments, Inc | 414.207 | -645.957 | 31.12.2023 |
0,35 % | Balyasny Asset Management LP | 413.137 | -765.741 | 31.12.2023 |
0,35 % | Medical Strategy GmbH | 410.643 | 10.800 | 31.12.2023 |
0,34 % | Dafna Capital Management, LLC | 400.000 | -79.538 | 31.12.2023 |
0,32 % | Ostrum Asset Management | 378.793 | 334.955 | 31.12.2023 |
0,31 % | Putnam Investment Management, L.L.C. | 365.335 | 147.486 | 31.12.2023 |
0,30 % | Qube Research & Technologies Ltd | 350.535 | 340.827 | 31.12.2023 |
0,30 % | DWS Investments UK Limited | 348.712 | 303.878 | 31.12.2023 |
0,29 % | Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 344.484 | 344.484 | 31.12.2023 |
0,29 % | BlackRock Asset Management Ireland Limited | 340.837 | 17.813 | 31.12.2023 |
0,27 % | Columbia Threadneedle Investments (US) | 316.909 | 1.491 | 31.12.2023 |
0,27 % | Nuveen LLC | 314.502 | -5.539 | 31.12.2023 |
0,25 % | Blum (Robert I) | 292.974 | 19.424 | 14.3.2024 |
0,25 % | BlackRock Investment Management, LLC | 291.194 | -1.989 | 31.12.2023 |
0,25 % | Parametric Portfolio Associates LLC | 289.702 | 23.706 | 31.12.2023 |
0,25 % | Deep Track Capital LP | 288.949 | 288.949 | 31.12.2023 |
0,24 % | Rhumbline Advisers Ltd. Partnership | 281.842 | 6.973 | 31.12.2023 |
0,23 % | BNY Mellon Asset Management | 275.689 | 823 | 31.12.2023 |
0,23 % | UBS Financial Services, Inc. | 274.308 | 77.637 | 31.12.2023 |
0,23 % | Citadel Advisors LLC | 272.593 | -959.231 | 31.12.2023 |
0,23 % | Candriam Belgium S.A. | 267.240 | -236.000 | 31.12.2023 |
0,23 % | Legal & General Investment Management Ltd. | 266.487 | -689 | 31.12.2023 |
0,22 % | Rafferty Asset Management LLC | 263.275 | 16.353 | 31.12.2023 |
0,22 % | Pinnacle Associates Ltd. | 258.358 | -971 | 31.12.2023 |
0,21 % | Russell Investments Trust Company | 252.122 | -37.435 | 31.12.2023 |
0,21 % | Barclays Bank PLC | 246.664 | 85.984 | 31.12.2023 |
0,20 % | Checkpoint Capital L.P. | 230.000 | 230.000 | 31.12.2023 |
0,19 % | Sphera Funds Management Ltd. | 223.820 | -10.113 | 31.12.2023 |
0,19 % | Driehaus Capital Management, LLC | 220.384 | 220.384 | 31.12.2023 |
0,19 % | Tekla Capital Management LLC_NLE | 219.025 | 0 | 30.6.2023 |
0,19 % | BlackRock Advisors (UK) Limited | 218.431 | -140.225 | 31.3.2024 |
0,18 % | Barclays Capital Inc. | 216.891 | -193.109 | 31.12.2023 |
0,18 % | Brown Advisory | 208.569 | 208.569 | 29.2.2024 |
0,17 % | Eagle Asset Management, Inc. | 203.547 | -193.223 | 31.12.2023 |
0,17 % | PSP Investments | 203.472 | 84.820 | 31.12.2023 |
0,17 % | BofA Global Research (US) | 203.309 | -22.684 | 31.12.2023 |
0,17 % | Integral Health Asset Management, LLC | 200.000 | -600.000 | 31.12.2023 |
0,17 % | BNP Paribas Securities Corp. North America | 198.886 | 96.081 | 31.12.2023 |
0,17 % | Cantor Fitzgerald, L.P | 197.282 | 197.282 | 31.12.2023 |
0,16 % | Goldman Sachs Asset Management, L.P. | 193.913 | 23.274 | 31.12.2023 |
0,16 % | Victory Capital Management Inc. | 191.654 | 174.848 | 31.12.2023 |
0,16 % | Invesco Capital Management LLC | 189.096 | -60.999 | 31.12.2023 |
0,16 % | JP Morgan Asset Management | 184.155 | -52.972 | 31.12.2023 |
0,15 % | TD Asset Management Inc. | 182.040 | 82.400 | 31.12.2023 |
0,15 % | Two Sigma Investments, LP | 179.462 | -94.101 | 31.12.2023 |
0,15 % | Superstring Capital Management LP | 177.603 | 177.603 | 31.12.2023 |
0,15 % | Voya Investment Management LLC | 176.742 | -677 | 31.12.2023 |
0,15 % | DWS Investment S.A. | 170.647 | 170.647 | 31.12.2023 |
0,14 % | Schweizerische Nationalbank | 170.300 | -29.500 | 31.12.2023 |
0,14 % | HealthCor Management, L.P. | 164.440 | -270.120 | 31.12.2022 |
0,14 % | Affinity Asset Advisors LLC | 160.000 | -70.366 | 31.12.2023 |
0,14 % | Citi Investment Research (US) | 158.974 | 16.260 | 31.12.2023 |
0,13 % | Point72 Asset Management, L.P. | 157.100 | 157.100 | 31.12.2023 |