8,62398 % | Wellington Management Company, LLP | 7.339.004 | -97.612 | 30.6.2024 |
7,67665 % | BlackRock Institutional Trust Company, N.A. | 6.532.828 | 283.661 | 30.6.2024 |
6,72392 % | Kynam Capital Management LP | 5.722.057 | 62.057 | 30.6.2024 |
5,61942 % | The Vanguard Group, Inc. | 4.782.124 | -129.895 | 30.6.2024 |
4,56926 % | Avoro Capital Advisors LLC | 3.888.437 | -333.785 | 30.6.2024 |
4,43105 % | State Street Global Advisors (US) | 3.770.826 | 148.491 | 30.9.2024 |
4,24633 % | Eversept Partners, LP | 3.613.631 | 480.518 | 30.6.2024 |
3,91892 % | Avidity Partners Management LP | 3.335.000 | 922.500 | 30.6.2024 |
3,27010 % | Point72 Asset Management, L.P. | 2.782.853 | 716.168 | 30.6.2024 |
2,53075 % | Sofinnova Investments, Inc | 2.153.669 | 545.129 | 30.6.2024 |
2,26240 % | OrbiMed Advisors, LLC | 1.925.300 | 176.300 | 30.6.2024 |
2,24515 % | Geode Capital Management, L.L.C. | 1.910.623 | 132.075 | 30.6.2024 |
2,15091 % | Marshall Wace LLP | 1.830.427 | -201.632 | 30.6.2024 |
1,82397 % | Two Sigma Investments, LP | 1.552.199 | 377.795 | 30.6.2024 |
1,81899 % | Franklin Advisers, Inc. | 1.547.963 | 72.729 | 30.6.2024 |
1,81613 % | Woodline Partners LP | 1.545.528 | 1.241 | 30.6.2024 |
1,65943 % | StemPoint Capital LP | 1.412.176 | 311.188 | 30.6.2024 |
1,39392 % | Candriam Luxembourg S.A. | 1.186.228 | 0 | 30.9.2024 |
1,32719 % | Goldman Sachs & Company, Inc. | 1.129.438 | 30.137 | 30.6.2024 |
1,25207 % | Millennium Management LLC | 1.065.508 | 383.634 | 30.6.2024 |
1,20447 % | Aisling Capital Management LP | 1.025.000 | 0 | 30.6.2024 |
1,13996 % | Candriam Belgium S.A. | 970.106 | -74.926 | 30.6.2024 |
1,05170 % | Kingdon Capital Management, L.L.C. | 894.993 | 0 | 30.6.2024 |
1,02820 % | Foresite Capital Management, LLC | 875.000 | 0 | 30.6.2024 |
1,01058 % | Adage Capital Management, L.P. | 860.000 | -40.000 | 30.6.2024 |
0,97121 % | Soleus Capital Management, L.P. | 826.500 | 457.500 | 30.6.2024 |
0,96945 % | Commodore Capital LP | 825.000 | 506.149 | 30.6.2024 |
0,96874 % | BlackRock Financial Management, Inc. | 824.394 | 38.560 | 30.6.2024 |
0,96598 % | Sphera Funds Management Ltd. | 822.047 | 9.083 | 30.6.2024 |
0,95468 % | BofA Global Research (US) | 812.433 | -805.740 | 30.6.2024 |
0,92572 % | BNP Paribas Asset Management USA, Inc. | 787.785 | 69.345 | 30.9.2024 |
0,77212 % | Dafna Capital Management, LLC | 657.074 | -2.500 | 30.6.2024 |
0,77115 % | Federated Hermes Global Investment Management Corp. | 656.250 | 117.536 | 30.6.2024 |
0,76908 % | Charles Schwab Investment Management, Inc. | 654.489 | 19.282 | 30.6.2024 |
0,75251 % | First Turn Management, LLC | 640.389 | 640.389 | 30.6.2024 |
0,74612 % | Northern Trust Investments, Inc. | 634.946 | -41.048 | 30.6.2024 |
0,73528 % | ExodusPoint Capital Management, LP | 625.723 | 339.393 | 30.6.2024 |
0,70587 % | Parkman Healthcare Partners LLC | 600.698 | -184.113 | 30.6.2024 |
0,69846 % | Granahan Investment Management, LLC | 594.386 | 197.508 | 30.6.2024 |
0,65004 % | Nuveen LLC | 553.187 | 162.265 | 30.6.2024 |
0,64811 % | Prosight Capital | 551.544 | 551.544 | 30.6.2024 |
0,64503 % | JP Morgan Asset Management | 548.917 | -44.379 | 30.6.2024 |
0,60974 % | Ensign Peak Advisors, Inc. | 518.885 | 4.033 | 30.6.2024 |
0,56840 % | Columbia Threadneedle Investments (US) | 483.712 | 2.811 | 30.6.2024 |
0,54762 % | Assenagon Asset Management S.A. | 466.028 | 37.079 | 30.9.2024 |
0,53259 % | Nantahala Capital Management, LLC | 453.232 | -12.027 | 30.6.2024 |
0,52073 % | Morgan Stanley & Co. LLC | 443.145 | -1.088.823 | 30.6.2024 |
0,50779 % | Algert Global LLC | 432.128 | 6.455 | 30.6.2024 |
0,49313 % | Saturn V Capital Management LP | 419.654 | 21.657 | 30.6.2024 |
0,47614 % | Palo Alto Investors LP | 405.193 | 0 | 30.6.2024 |
0,45518 % | PFM Health Sciences, LP | 387.357 | -271.337 | 30.6.2024 |
0,43478 % | SilverArc Capital Management, LLC | 370.000 | 370.000 | 30.6.2024 |
0,41128 % | Ghost Tree Capital, LLC | 350.000 | 200.000 | 30.6.2024 |
0,35664 % | Goldman Sachs Asset Management, L.P. | 303.499 | 108.246 | 30.6.2024 |
0,34936 % | Qube Research & Technologies Ltd | 297.303 | 203.414 | 30.6.2024 |
0,33352 % | T. Rowe Price Investment Management, Inc. | 283.827 | -2.175.408 | 30.6.2024 |
0,31455 % | Parametric Portfolio Associates LLC | 267.682 | 26.396 | 30.6.2024 |
0,30655 % | Schonfeld Strategic Advisors LLC | 260.876 | -524.768 | 30.6.2024 |
0,28545 % | Macquarie Investment Management | 242.919 | -73 | 30.6.2024 |
0,27219 % | BlackRock Investment Management, LLC | 231.634 | 16.095 | 30.6.2024 |
0,26865 % | HOOPP Investment Management | 228.625 | -551.375 | 30.6.2024 |
0,26851 % | Rhenman & Partners Asset Management AB | 228.500 | 50.000 | 30.6.2024 |
0,25182 % | Renaissance Technologies LLC | 214.300 | 135.200 | 30.6.2024 |
0,24244 % | BNY Mellon Asset Management | 206.319 | 24.260 | 30.6.2024 |
0,23394 % | Peregrine Capital Management, LLC | 199.086 | 427 | 30.9.2024 |
0,22324 % | Citadel Advisors LLC | 189.981 | 156.172 | 30.6.2024 |
0,21580 % | Voya Investment Management LLC | 183.649 | -13.375 | 30.6.2024 |
0,20907 % | Rafferty Asset Management LLC | 177.920 | -195.318 | 30.6.2024 |
0,19708 % | TwinBeech Capital LP | 167.714 | 95.831 | 30.6.2024 |
0,19261 % | Metzger (Michael A) | 163.909 | 3.750 | 8.3.2024 |
0,18214 % | Zimmer Partners, LP | 155.000 | 0 | 30.6.2024 |
0,18015 % | Jane Street Capital, L.L.C. | 153.311 | 39.783 | 30.6.2024 |
0,17697 % | Schweizerische Nationalbank | 150.600 | 0 | 30.6.2024 |
0,17626 % | Casdin Capital, LLC | 150.000 | 0 | 30.6.2024 |
0,17232 % | D. E. Shaw & Co., L.P. | 146.643 | 138.119 | 30.6.2024 |
0,16988 % | Verition Fund Management LLC | 144.566 | -202.296 | 30.6.2024 |
0,16837 % | Crestline Investors, Inc. | 143.280 | 39.570 | 30.6.2024 |
0,16093 % | BlackRock Advisors (UK) Limited | 136.952 | 1.627 | 30.9.2024 |
0,14706 % | UBS Financial Services, Inc. | 125.152 | -144.659 | 30.6.2024 |
0,14017 % | Rhumbline Advisers Ltd. Partnership | 119.285 | 10.291 | 30.6.2024 |
0,13903 % | BlackRock Asset Management Ireland Limited | 118.312 | 1.362 | 30.6.2024 |
0,13458 % | Yelin Lapidot Mutual Funds Management Ltd | 114.530 | 114.530 | 30.9.2023 |
0,12979 % | UBS O'Connor LLC | 110.454 | 2.023 | 30.6.2024 |
0,12735 % | Yelin Lapidot Provident Funds Management Ltd | 108.377 | -6.153 | 30.9.2024 |
0,12200 % | Knott Partners Management, LLC | 103.826 | 38.351 | 30.6.2024 |
0,11989 % | Susquehanna International Group, LLP | 102.027 | -634.121 | 30.6.2024 |
0,11931 % | PGIM Quantitative Solutions LLC | 101.530 | 85.770 | 30.6.2024 |
0,11180 % | Axiom Investors | 95.140 | 1.075 | 30.6.2024 |
0,11083 % | New Jersey Division of Investment | 94.313 | -20.071 | 30.6.2024 |
0,11035 % | Trexquant Investment LP | 93.906 | 19.314 | 30.6.2024 |
0,10967 % | Podlesak (Dennis G) | 93.333 | -2.000 | 8.3.2024 |
0,10890 % | Aperio Group, LLC | 92.675 | 13.305 | 30.6.2024 |
0,10018 % | AllianceBernstein L.P. | 85.250 | 7.790 | 30.6.2024 |
0,10012 % | Wellington Management Singapore Pte. Ltd. | 85.200 | 85.200 | 31.3.2024 |
0,10012 % | Wellington Management Japan Pte Ltd | 85.200 | -54.891 | 30.6.2023 |
0,09910 % | Legal & General Investment Management Ltd. | 84.330 | 14.552 | 30.6.2024 |
0,09784 % | Propel Bio Management, LLC | 83.259 | 0 | 30.6.2024 |
0,09735 % | PanAgora Asset Management Inc. | 82.849 | -154.157 | 30.6.2024 |
0,09097 % | Mellon Investments Corporation | 77.412 | 19.883 | 30.6.2024 |
0,08927 % | Seven Eight Capital, LP | 75.971 | 66.332 | 30.6.2024 |