10,83259 % | Fidelity Management & Research Company LLC | 14.392.175 | -238.466 | 30.6.2024 |
7,35890 % | The Vanguard Group, Inc. | 9.777.040 | 58.630 | 30.6.2024 |
6,67538 % | Janus Henderson Investors | 8.868.907 | 1.195.039 | 30.6.2024 |
6,17474 % | RA Capital Management, LP | 8.203.754 | 0 | 30.6.2024 |
5,93509 % | BlackRock Institutional Trust Company, N.A. | 7.885.361 | 314.385 | 30.6.2024 |
3,45707 % | Wellington Management Company, LLP | 4.593.066 | -326.304 | 30.6.2024 |
3,11120 % | Capital Research Global Investors | 4.133.544 | -6.977 | 30.6.2024 |
3,02769 % | T. Rowe Price Investment Management, Inc. | 4.022.589 | 469.622 | 30.6.2024 |
2,53436 % | State Street Global Advisors (US) | 3.367.147 | 30.055 | 30.6.2024 |
2,31719 % | T. Rowe Price Associates, Inc. | 3.078.615 | -8.212 | 30.6.2024 |
1,83785 % | Geode Capital Management, L.L.C. | 2.441.772 | 154.397 | 30.6.2024 |
1,63722 % | Franklin Advisers, Inc. | 2.175.205 | 278.124 | 30.6.2024 |
1,56627 % | Darwin Global Management Ltd | 2.080.946 | -669.858 | 30.6.2024 |
1,45623 % | Driehaus Capital Management, LLC | 1.934.747 | 66.940 | 30.6.2024 |
1,45217 % | Westfield Capital Management Company, L.P. | 1.929.348 | 343.253 | 30.6.2024 |
1,40193 % | Perceptive Advisors LLC | 1.862.608 | -70.151 | 30.6.2024 |
1,33612 % | Fidelity Institutional Asset Management | 1.775.165 | 144.647 | 30.6.2024 |
1,30575 % | AllianceBernstein L.P. | 1.734.821 | -45.882 | 30.6.2024 |
1,04104 % | Jennison Associates LLC | 1.383.131 | 126.248 | 30.6.2024 |
0,98633 % | Fred Alger Management, LLC | 1.310.436 | -86.275 | 30.6.2024 |
0,98224 % | Commodore Capital LP | 1.305.000 | 445.000 | 30.6.2024 |
0,92174 % | BlackRock Financial Management, Inc. | 1.224.621 | 45.069 | 30.6.2024 |
0,82794 % | Cormorant Asset Management, LP | 1.100.000 | 415.000 | 30.6.2024 |
0,78233 % | Frazier Life Sciences Management, L.P. | 1.039.405 | -100.000 | 30.6.2024 |
0,76700 % | Invesco Advisers, Inc. | 1.019.035 | -1.858 | 30.6.2024 |
0,75518 % | JP Morgan Asset Management | 1.003.336 | 37.836 | 30.6.2024 |
0,74098 % | Norges Bank Investment Management (NBIM) | 984.464 | 68.952 | 30.6.2024 |
0,67906 % | Fidelity Investments Canada ULC | 902.197 | 7.267 | 30.6.2024 |
0,65952 % | Charles Schwab Investment Management, Inc. | 876.237 | 42.619 | 30.6.2024 |
0,63085 % | Northern Trust Investments, Inc. | 838.142 | -28.926 | 30.6.2024 |
0,60839 % | Braidwell LP | 808.303 | -404.400 | 30.6.2024 |
0,59905 % | OrbiMed Advisors, LLC | 795.900 | -270.231 | 30.6.2024 |
0,59690 % | Pivotal Bioventure Partners Investment Advisor LLC | 793.036 | 0 | 30.6.2024 |
0,56694 % | Kynam Capital Management LP | 753.240 | 8.240 | 30.6.2024 |
0,56450 % | Novo Holdings A/S | 750.000 | -200.000 | 30.9.2024 |
0,55634 % | Eventide Asset Management, LLC | 739.153 | 81.947 | 30.6.2024 |
0,53207 % | Woodline Partners LP | 706.903 | 313.199 | 30.6.2024 |
0,51777 % | Maverick Capital, Ltd. | 687.908 | 332.777 | 30.6.2024 |
0,47208 % | Paradigm BioCapital Advisors LP | 627.202 | -612.793 | 30.6.2024 |
0,43279 % | Avoro Capital Advisors LLC | 575.000 | 0 | 30.6.2024 |
0,40110 % | Pictet Asset Management Ltd. | 532.904 | -328.665 | 30.6.2024 |
0,39711 % | American Century Investment Management, Inc. | 527.594 | 65.870 | 30.6.2024 |
0,34825 % | Ensign Peak Advisors, Inc. | 462.682 | -13.018 | 30.6.2024 |
0,33291 % | Amundi Asset Management US, Inc. | 442.308 | 139.951 | 30.6.2024 |
0,32198 % | Pickering (Grant E) | 427.779 | -15.000 | 8.10.2024 |
0,32037 % | Federated Hermes Global Investment Management Corp. | 425.640 | -110 | 30.6.2024 |
0,31516 % | Balyasny Asset Management LP | 418.715 | 418.715 | 30.6.2024 |
0,29015 % | BofA Global Research (US) | 385.494 | 175.420 | 30.6.2024 |
0,28649 % | Goldman Sachs & Company, Inc. | 380.629 | -31.175 | 30.6.2024 |
0,27639 % | Brown Advisory | 367.217 | 316.734 | 30.6.2024 |
0,26174 % | Goldman Sachs Asset Management, L.P. | 347.747 | 61.059 | 30.6.2024 |
0,26153 % | Allspring Global Investments, LLC | 347.474 | 3.922 | 30.9.2024 |
0,23884 % | Nuveen LLC | 317.323 | 10.052 | 30.6.2024 |
0,23515 % | TD Asset Management Inc. | 312.426 | 31.138 | 30.6.2024 |
0,23146 % | Victory Capital Management Inc. | 307.516 | 26.641 | 30.6.2024 |
0,22755 % | BlackRock Investment Management, LLC | 302.327 | 23.446 | 30.6.2024 |
0,22580 % | EcoR1 Capital, LLC | 300.000 | 0 | 30.6.2024 |
0,22580 % | Tang Capital Management, LLC | 300.000 | 0 | 30.6.2024 |
0,21827 % | Farallon Capital Management, L.L.C. | 290.000 | -87.400 | 30.6.2024 |
0,21499 % | Putnam Investment Management, L.L.C. | 285.640 | 41.171 | 30.6.2024 |
0,21376 % | Avidity Partners Management LP | 284.000 | 0 | 30.6.2024 |
0,21316 % | BlackRock Investment Management (UK) Ltd. | 283.204 | 26.464 | 30.6.2024 |
0,21252 % | Eagle Asset Management, Inc. | 282.351 | -56.449 | 30.6.2024 |
0,21030 % | Voya Investment Management LLC | 279.398 | 96.267 | 30.6.2024 |
0,20594 % | Cercano Management LLC | 273.608 | 1.457 | 30.6.2024 |
0,20550 % | Comerica, Inc. | 273.025 | 84.941 | 30.6.2024 |
0,20165 % | BNY Mellon Asset Management | 267.915 | 20.855 | 30.6.2024 |
0,19602 % | Columbia Threadneedle Investments (US) | 260.431 | 162.012 | 30.6.2024 |
0,19591 % | First Turn Management, LLC | 260.281 | 0 | 30.6.2024 |
0,18534 % | Lord, Abbett & Co. LLC | 246.242 | -138.121 | 30.6.2024 |
0,17327 % | D. E. Shaw & Co., L.P. | 230.207 | -137.042 | 30.6.2024 |
0,16656 % | Morgan Stanley & Co. LLC | 221.296 | -72.415 | 30.6.2024 |
0,16234 % | Saturn V Capital Management LP | 215.680 | 30.505 | 30.6.2024 |
0,15334 % | Millennium Management LLC | 203.731 | -3.251 | 30.6.2024 |
0,14010 % | ClearBridge Investments, LLC | 186.141 | 186.141 | 30.6.2024 |
0,13943 % | Soleus Capital Management, L.P. | 185.250 | -22.500 | 30.6.2024 |
0,13848 % | BlackRock Advisors (UK) Limited | 183.988 | 3.293 | 30.9.2024 |
0,13666 % | Parametric Portfolio Associates LLC | 181.563 | -7.614 | 30.6.2024 |
0,13646 % | Schweizerische Nationalbank | 181.300 | 3.300 | 30.6.2024 |
0,13261 % | Mellon Investments Corporation | 176.182 | 30.003 | 30.6.2024 |
0,12479 % | Citi Investment Research (US) | 165.795 | 20.928 | 30.6.2024 |
0,12407 % | SEI Investments Management Corporation | 164.843 | 67.939 | 30.6.2024 |
0,12226 % | Segall Bryant & Hamill, LLC | 162.432 | 4.411 | 30.6.2024 |
0,11990 % | Rhumbline Advisers Ltd. Partnership | 159.295 | 11.001 | 30.6.2024 |
0,11968 % | Macquarie Investment Management | 159.012 | 39.039 | 30.6.2024 |
0,11910 % | BlackRock Asset Management Ireland Limited | 158.235 | 1.236 | 30.6.2024 |
0,11499 % | California Public Employees' Retirement System | 152.778 | -4.208 | 30.6.2024 |
0,11304 % | Parkman Healthcare Partners LLC | 150.191 | 235 | 30.6.2024 |
0,11290 % | Ghost Tree Capital, LLC | 150.000 | 55.000 | 30.6.2024 |
0,10517 % | First Light Asset Management, LLC | 139.729 | 79.445 | 30.6.2024 |
0,09916 % | Manulife Investment Management (North America) Limited | 131.749 | 12.667 | 30.6.2024 |
0,09631 % | Barclays Bank PLC | 127.952 | -1.300 | 30.6.2024 |
0,08653 % | Pier Capital, LLC | 114.969 | -12.415 | 30.6.2024 |
0,08531 % | Tri Locum Partners LP | 113.344 | 113.344 | 30.6.2024 |
0,08309 % | Acuta Capital Partners, LLC | 110.400 | 5.570 | 30.6.2024 |
0,08136 % | Neuberger Berman, LLC | 108.092 | 5.781 | 30.6.2024 |
0,08024 % | Jane Street Capital, L.L.C. | 106.611 | 90.929 | 30.6.2024 |
0,07976 % | JPMorgan Asset Management U.K. Limited | 105.974 | 1.052 | 30.6.2024 |
0,07902 % | Legal & General Investment Management Ltd. | 104.984 | 10.201 | 30.6.2024 |
0,07821 % | MFS Investment Management | 103.906 | 2.967 | 31.8.2024 |