7,33082 % | BlackRock Institutional Trust Company, N.A. | 7.690.027 | 1.137.557 | 30.6.2024 |
6,24480 % | Teoxane SA | 6.550.800 | 2.105.000 | 20.10.2023 |
5,96441 % | Franklin Advisers, Inc. | 6.256.664 | 12.872 | 30.6.2024 |
5,69977 % | The Vanguard Group, Inc. | 5.979.062 | 596.053 | 30.6.2024 |
5,01152 % | Palo Alto Investors LP | 5.257.086 | 9.082 | 30.6.2024 |
3,40051 % | Polar Capital LLP | 3.567.139 | -317.680 | 30.6.2024 |
2,66921 % | Stonepine Capital Management, LLC | 2.800.000 | 823.658 | 30.6.2024 |
2,53274 % | Rubric Capital Management LP | 2.656.847 | 0 | 30.6.2024 |
2,19062 % | Geode Capital Management, L.L.C. | 2.297.965 | 327.127 | 30.6.2024 |
2,17697 % | State Street Global Advisors (US) | 2.283.640 | -75.137 | 30.6.2024 |
2,14236 % | JP Morgan Asset Management | 2.247.339 | -109.526 | 30.6.2024 |
2,13299 % | Federated MDTA LLC | 2.237.505 | 755.803 | 30.6.2024 |
1,58236 % | Water Island Capital, LLC | 1.659.892 | 10.000 | 30.9.2024 |
1,56573 % | Beryl Capital Management, LLC | 1.642.448 | 1.642.448 | 5.9.2024 |
1,05515 % | Foley (Mark J) | 1.106.848 | 1.000 | 30.6.2024 |
0,99195 % | Nuveen LLC | 1.040.555 | 696.030 | 30.6.2024 |
0,97585 % | Baron Capital Management, Inc. | 1.023.663 | 0 | 30.6.2024 |
0,72724 % | Northern Trust Investments, Inc. | 762.874 | 4.188 | 30.6.2024 |
0,72156 % | Millennium Management LLC | 756.912 | 604.547 | 30.6.2024 |
0,71457 % | Charles Schwab Investment Management, Inc. | 749.587 | 49.537 | 30.6.2024 |
0,70476 % | Morgan Stanley & Co. LLC | 739.297 | -225.757 | 30.6.2024 |
0,69608 % | Rice Hall James & Associates, LLC | 730.190 | 18.118 | 30.9.2024 |
0,66893 % | Rhenman & Partners Asset Management AB | 701.707 | 0 | 30.6.2024 |
0,61411 % | Two Sigma Investments, LP | 644.203 | 386.806 | 30.6.2024 |
0,58226 % | Walleye Capital LLC | 610.792 | -11.334 | 30.6.2024 |
0,57975 % | Goldman Sachs & Company, Inc. | 608.160 | 197.141 | 30.6.2024 |
0,57197 % | Perceptive Advisors LLC | 600.000 | 0 | 30.6.2024 |
0,54528 % | Renaissance Technologies LLC | 572.000 | 198.300 | 30.6.2024 |
0,51038 % | Hightower Advisors, LLC | 535.387 | 90.000 | 30.6.2024 |
0,47664 % | Integral Health Asset Management, LLC | 500.000 | 500.000 | 30.6.2024 |
0,47664 % | EULAV Asset Management | 500.000 | 0 | 30.6.2024 |
0,43573 % | EW Healthcare Partners | 457.085 | 0 | 30.6.2024 |
0,43207 % | Alpine Associates Management Inc. | 453.243 | -5.957 | 30.9.2024 |
0,42096 % | ExodusPoint Capital Management, LP | 441.584 | 441.584 | 30.6.2024 |
0,39767 % | Graham Capital Management, L.P. | 417.161 | 417.161 | 30.6.2024 |
0,38132 % | CM Management, LLC | 400.000 | 150.000 | 30.6.2024 |
0,38132 % | Tang Capital Management, LLC | 400.000 | 200.000 | 30.6.2024 |
0,32673 % | J.P. Morgan Securities LLC | 342.744 | -87.173 | 30.6.2024 |
0,31012 % | UBS O'Connor LLC | 325.314 | 70.647 | 30.6.2024 |
0,30441 % | Lane Generational, LLC | 319.322 | 319.322 | 30.6.2024 |
0,28384 % | Goldman Sachs Asset Management, L.P. | 297.744 | 165.314 | 30.6.2024 |
0,27694 % | William Blair & Company, L.L.C. (Research) | 290.515 | -38.752 | 30.6.2024 |
0,27524 % | International Biotechnology Trust PLC | 288.726 | 0 | 30.9.2023 |
0,27451 % | BlackRock Investment Management, LLC | 287.961 | 78.202 | 30.6.2024 |
0,27078 % | BlackRock Financial Management, Inc. | 284.053 | 46.179 | 30.6.2024 |
0,23869 % | JPMorgan Asset Management U.K. Limited | 250.388 | -18.027 | 30.6.2024 |
0,23832 % | DCF Advisers, LLC | 250.000 | -13.372 | 30.6.2024 |
0,23832 % | Moore Capital Management, LP | 250.000 | 0 | 30.6.2024 |
0,23740 % | Citadel Advisors LLC | 249.029 | 198.366 | 30.6.2024 |
0,23356 % | AlphaCentric Advisors LLC. | 245.000 | 0 | 30.9.2024 |
0,23356 % | LifeSci Fund Management LLC | 245.000 | 0 | 30.6.2024 |
0,22908 % | BNY Mellon Asset Management | 240.300 | 49.873 | 30.6.2024 |
0,21449 % | Ghost Tree Capital, LLC | 225.000 | -225.000 | 30.6.2024 |
0,19976 % | BlackRock Asset Management Ireland Limited | 209.545 | 48.030 | 30.6.2024 |
0,19169 % | AQR Capital Management, LLC | 201.080 | 170.960 | 30.6.2024 |
0,18784 % | PDT Partners, LLC | 197.049 | 197.049 | 30.6.2024 |
0,18556 % | Schweizerische Nationalbank | 194.650 | 0 | 30.6.2024 |
0,18462 % | Schilke (Tobin C) | 193.666 | 1.000 | 30.6.2024 |
0,18455 % | Schonfeld Strategic Advisors LLC | 193.591 | 193.591 | 30.6.2024 |
0,18357 % | BlackRock Advisors (UK) Limited | 192.565 | 2.094 | 30.9.2024 |
0,17493 % | FNY Investment Advisers LLC | 183.500 | 183.500 | 30.9.2024 |
0,17155 % | BofA Global Research (US) | 179.951 | -324.725 | 30.6.2024 |
0,16871 % | Susquehanna International Group, LLP | 176.973 | 57.064 | 30.6.2024 |
0,16010 % | Columbia Threadneedle Investments (US) | 167.948 | -1.963 | 30.6.2024 |
0,15972 % | Sjuts (Dustin S) | 167.550 | 40.217 | 18.3.2024 |
0,15904 % | Fidelity Management & Research Company LLC | 166.828 | 159.200 | 30.6.2024 |
0,15626 % | Jane Street Capital, L.L.C. | 163.913 | 24.012 | 30.6.2024 |
0,15348 % | Norges Bank Investment Management (NBIM) | 161.000 | 0 | 30.6.2024 |
0,15331 % | Conestoga Capital Advisors, LLC | 160.821 | -1.547 | 31.3.2024 |
0,13762 % | Nebula Research & Development LLC | 144.365 | -30.502 | 30.6.2024 |
0,13466 % | Centiva Capital, LP | 141.259 | 126.259 | 30.6.2024 |
0,13444 % | Morgan Stanley Smith Barney LLC | 141.027 | 20.184 | 30.6.2024 |
0,13138 % | Moxie (Dwight) | 137.815 | 30.955 | 18.3.2024 |
0,13117 % | IndexIQ Advisors LLC | 137.594 | 137.594 | 30.9.2024 |
0,12998 % | Rhumbline Advisers Ltd. Partnership | 136.347 | 14.191 | 30.6.2024 |
0,11976 % | UBS Fund Management (Switzerland) AG | 125.627 | -54.521 | 30.6.2024 |
0,11508 % | AllianceBernstein L.P. | 120.720 | 30.220 | 30.6.2024 |
0,11093 % | Los Angeles Capital Management LLC | 116.368 | 23.450 | 30.6.2024 |
0,10991 % | BNP Paribas Securities Corp. North America | 115.291 | -96.404 | 30.6.2024 |
0,10950 % | Jordan (Erica) | 114.864 | -2.392 | 16.4.2024 |
0,10377 % | Hollander (David) | 108.853 | 0 | 8.3.2024 |
0,10294 % | D. E. Shaw & Co., L.P. | 107.980 | -190.130 | 30.6.2024 |
0,09951 % | JPMorgan Private Bank (United States) | 104.390 | 6.464 | 30.6.2024 |
0,09344 % | Mellon Investments Corporation | 98.021 | 31.137 | 30.6.2024 |
0,09278 % | California State Teachers Retirement System | 97.324 | -169 | 30.6.2024 |
0,09079 % | UBS Asset Management (Switzerland) | 95.234 | 15.033 | 30.6.2024 |
0,09005 % | Parametric Portfolio Associates LLC | 94.467 | -21.834 | 30.6.2024 |
0,09004 % | T. Rowe Price International Ltd | 94.453 | 25.092 | 30.6.2024 |
0,08801 % | Parallel Advisors, LLC | 92.323 | 92.323 | 30.6.2024 |
0,08608 % | PenderFund Capital Management, Ltd. | 90.300 | 90.300 | 31.8.2024 |
0,08427 % | Summit Wealth Strategies | 88.395 | 54.961 | 30.6.2024 |
0,08208 % | Deka Verm¿gensmanagement GmbH | 86.100 | 0 | 30.9.2024 |
0,08208 % | Deka Investment GmbH | 86.100 | 0 | 31.12.2023 |
0,07883 % | Tejara Capital Ltd. | 82.688 | -87.312 | 30.6.2024 |
0,07777 % | Jacobs Levy Equity Management, Inc. | 81.579 | 81.579 | 30.6.2024 |
0,07441 % | Inspire Investing | 78.055 | -61.024 | 30.9.2024 |
0,07440 % | Commonwealth Financial Network | 78.041 | -31.876 | 30.9.2024 |
0,07337 % | SG Americas Securities, L.L.C. | 76.963 | 76.963 | 30.9.2024 |
0,06787 % | Legal & General Investment Management Ltd. | 71.199 | -11.973 | 30.6.2024 |
0,06666 % | XTX Markets LLC | 69.926 | 15.267 | 30.6.2024 |