9,43 % | Federated Hermes Global Investment Management Corp. | 1.956.488 | -301.636 | 31-12-2022 |
8,47 % | Perceptive Advisors LLC | 1.757.160 | -182.563 | 31-12-2022 |
8,21 % | Deep Track Capital LP | 1.704.000 | 579.579 | 31-12-2022 |
7,15 % | Beryl Capital Management, LLC | 1.483.599 | 1.483.599 | 16-2-2023 |
6,57 % | Chicago Capital, LLC | 1.362.484 | 242.710 | 31-12-2022 |
5,59 % | BlackRock Institutional Trust Company, N.A. | 1.159.924 | 91.388 | 31-12-2022 |
5,18 % | Carlson Capital, L.P. | 1.075.000 | 1.075.000 | 17-2-2023 |
4,82 % | Millennium Management LLC | 999.363 | 611.796 | 21-2-2023 |
4,56 % | The Vanguard Group, Inc. | 945.227 | 31.052 | 31-12-2022 |
4,46 % | Franklin Advisers, Inc. | 924.773 | -487 | 31-12-2022 |
3,79 % | ArrowMark Colorado Holdings, LLC | 786.664 | -4.585 | 31-12-2022 |
3,68 % | Medical Strategy GmbH | 763.135 | 0 | 30-9-2022 |
3,06 % | GW&K Investment Management, LLC | 634.701 | -9.091 | 31-12-2022 |
3,00 % | Decheng Capital Management III (Cayman) LLC | 623.342 | 0 | 31-12-2022 |
2,48 % | Rice Hall James & Associates, LLC | 513.525 | 9.387 | 31-12-2022 |
2,35 % | Prosight Capital | 486.726 | -4.518 | 31-12-2022 |
2,24 % | Sphera Funds Management Ltd. | 463.828 | 104.828 | 31-12-2022 |
1,99 % | Tang Capital Management, LLC | 411.968 | -687.548 | 31-12-2022 |
1,68 % | State Street Global Advisors (US) | 348.114 | -2.430 | 31-12-2022 |
1,65 % | Saturn V Capital Management LLC | 341.827 | 341.827 | 31-12-2022 |
1,61 % | Geode Capital Management, L.L.C. | 333.211 | 20.467 | 31-12-2022 |
1,48 % | Platinum Asset Management | 306.834 | 39.917 | 31-12-2022 |
1,45 % | Privium Fund Management BV | 300.252 | 0 | 31-12-2022 |
1,30 % | Dimensional Fund Advisors, L.P. | 269.731 | 5.195 | 31-12-2022 |
1,29 % | Great Point Partners, LLC | 267.283 | 267.283 | 31-12-2022 |
1,28 % | MAI Capital Management, LLC | 265.364 | -141.469 | 31-12-2022 |
1,05 % | Endurant Capital Management LP | 217.209 | 44.588 | 31-12-2022 |
0,89 % | Cooper (Ronald Harold Wilfred) | 184.641 | -33.094 | 2-3-2023 |
0,76 % | Northern Trust Investments, Inc. | 157.275 | 6.165 | 31-12-2022 |
0,61 % | Fiera Capital Corporation | 126.109 | -2.377 | 31-12-2022 |
0,57 % | Streck (Paul) | 118.966 | 55.000 | 19-1-2023 |
0,56 % | Birchview Capital, LP | 117.000 | 0 | 31-12-2022 |
0,56 % | EQT Life Sciences | 116.376 | 11.500 | 30-6-2021 |
0,48 % | Samsara BioCapital, LLC | 100.000 | 0 | 31-12-2022 |
0,43 % | Renaissance Technologies LLC | 89.683 | -50.000 | 31-12-2022 |
0,42 % | BlackRock Financial Management, Inc. | 86.540 | 32.390 | 31-12-2022 |
0,40 % | Morgan Stanley & Co. LLC | 82.277 | -7.959 | 31-12-2022 |
0,36 % | Mattsson (Jan P) | 73.950 | -35.524 | 2-3-2023 |
0,31 % | Duncan (Jason G) | 64.490 | -3.296 | 2-3-2023 |
0,29 % | Parametric Portfolio Associates LLC | 60.726 | 29.482 | 31-12-2022 |
0,27 % | Stephenson (Pamela) | 56.763 | -22.242 | 2-3-2023 |
0,25 % | BNY Mellon Asset Management | 51.894 | 2.145 | 31-12-2022 |
0,25 % | Carter (Martha J) | 51.268 | -3.656 | 2-3-2023 |
0,25 % | Graham (Michelle) | 50.950 | -5.543 | 2-3-2023 |
0,24 % | Charles Schwab Investment Management, Inc. | 49.296 | 2.462 | 31-12-2022 |
0,23 % | BlackRock Investment Management, LLC | 47.565 | 1.062 | 31-12-2022 |
0,22 % | Harford Simon N R | 46.671 | -13.739 | 2-3-2023 |
0,22 % | Deka Vermögensmanagement GmbH | 45.000 | 0 | 31-12-2022 |
0,22 % | Manulife Investment Management (North America) Limited | 44.811 | 37.853 | 31-1-2023 |
0,21 % | Schweizerische Nationalbank | 42.600 | 1.700 | 31-12-2022 |
0,21 % | Jacobs Levy Equity Management, Inc. | 42.538 | 42.538 | 31-12-2022 |
0,20 % | Brandywine Global Investment Management, LLC | 42.168 | 0 | 31-12-2022 |
0,19 % | Nuveen LLC | 40.260 | -52.803 | 31-12-2022 |
0,18 % | International Biotechnology Trust PLC | 38.000 | 21.907 | 31-12-2022 |
0,17 % | Aperio Group, LLC | 35.366 | 4.138 | 31-12-2022 |
0,17 % | Weiss Multi-Strategy Advisers LLC | 35.322 | 322 | 31-12-2022 |
0,17 % | Deka Investment GmbH | 35.000 | 35.000 | 30-6-2022 |
0,14 % | Wilmington Trust Investment Advisors, Inc. | 29.524 | 4.562 | 31-12-2022 |
0,12 % | AllianceBernstein L.P. | 25.200 | 2.300 | 31-12-2022 |
0,12 % | Point72 Asset Management, L.P. | 24.200 | -53.900 | 31-12-2022 |
0,11 % | Northern Trust Global Investments | 23.841 | 719 | 31-12-2022 |
0,11 % | PDT Partners, LLC | 23.587 | 23.587 | 31-12-2022 |
0,11 % | California State Teachers Retirement System | 22.599 | 645 | 31-12-2022 |
0,11 % | Rhumbline Advisers Ltd. Partnership | 22.452 | 1.155 | 31-12-2022 |
0,09 % | ARIAD Asset Management GmbH | 19.099 | 0 | 31-12-2022 |
0,09 % | Schonfeld Strategic Advisors LLC | 18.393 | 18.393 | 31-12-2022 |
0,08 % | Granite Investment Partners, LLC | 16.162 | -734 | 31-1-2023 |
0,08 % | Apo Asset Management GmbH | 15.964 | 0 | 31-1-2023 |
0,08 % | State of Wisconsin Investment Board | 15.802 | -1.081 | 31-12-2022 |
0,07 % | William Blair & Company, L.L.C. (Research) | 15.456 | 75 | 31-12-2022 |
0,07 % | State Street Global Advisors Ireland Limited | 14.594 | 0 | 31-1-2023 |
0,07 % | Mellon Investments Corporation | 14.191 | 1.057 | 31-12-2022 |
0,07 % | Alps Advisors, Inc. | 14.058 | 3.310 | 31-12-2022 |
0,07 % | BlackRock Advisors (UK) Limited | 13.743 | 291 | 28-2-2023 |
0,06 % | Cheyne Capital Management (UK) LLP | 13.364 | 13.364 | 31-12-2022 |
0,06 % | Ensign Peak Advisors, Inc. | 13.090 | 6.450 | 31-12-2022 |
0,06 % | Fidelity Management & Research Company LLC | 13.049 | 11.657 | 31-12-2022 |
0,06 % | Goldman Sachs Asset Management, L.P. | 12.706 | 12.706 | 31-12-2022 |
0,06 % | BofA Global Research (US) | 12.342 | 6.108 | 31-12-2022 |
0,06 % | New York State Common Retirement Fund | 11.751 | -13 | 31-12-2022 |
0,06 % | Jump Financial, LLC | 11.700 | 11.700 | 31-12-2022 |
0,05 % | Credit Suisse Asset Management | 11.279 | 0 | 31-12-2022 |
0,05 % | Dimensional Fund Advisors, Ltd. | 11.256 | 0 | 31-1-2023 |
0,05 % | BlackRock Asset Management Ireland Limited | 11.164 | 513 | 31-12-2022 |
0,05 % | Two Sigma Investments, LP | 11.000 | -900 | 31-12-2022 |
0,05 % | JPMorgan Private Bank (United States) | 10.637 | 1.232 | 31-12-2022 |
0,05 % | Hopkinson (Craig C M.D.) | 10.495 | 10.495 | 1-12-2022 |
0,05 % | MetLife Investment Management, LLC | 9.864 | 0 | 31-12-2022 |
0,05 % | Connor, Clark & Lunn Investment Management Ltd. | 9.724 | -337 | 31-12-2022 |
0,04 % | Russell Investments Trust Company | 9.289 | 8.513 | 31-12-2022 |
0,04 % | Cubist Systematic Strategies, LLC | 8.640 | 4.930 | 31-12-2022 |
0,04 % | SunAmerica Asset Management, LLC | 8.613 | 442 | 31-12-2022 |
0,04 % | DWS Investments UK Limited | 7.848 | 990 | 31-12-2022 |
0,03 % | Legal & General Investment Management Ltd. | 6.990 | 434 | 31-12-2022 |
0,03 % | E Fund Management Co. Ltd. | 6.623 | 4.498 | 30-6-2022 |
0,03 % | UBS Financial Services, Inc. | 6.164 | 5.399 | 31-12-2022 |
0,03 % | Barclays Bank PLC | 6.163 | 4.160 | 31-12-2022 |
0,03 % | Horn Patrick Taylor | 6.086 | 2.066 | 1-4-2022 |
0,03 % | Perinvest (UK) Ltd. | 6.000 | 0 | 30-6-2022 |
0,03 % | Zürcher Kantonalbank (Asset Management) | 5.713 | 813 | 31-12-2022 |