9,10 % | The Vanguard Group, Inc. | 25.418.388 | 979.857 | 31-12-2023 |
8,50 % | RA Capital Management, LP | 23.750.601 | 10.428.313 | 31-12-2023 |
6,68 % | BlackRock Institutional Trust Company, N.A. | 18.646.679 | 1.793.786 | 31-12-2023 |
5,88 % | Redmile Group, LLC | 16.423.922 | -1.079.495 | 31-12-2023 |
3,95 % | Janus Henderson Investors | 11.043.986 | -6.640.830 | 31-12-2023 |
2,89 % | State Street Global Advisors (US) | 8.075.671 | -1.476.181 | 31-12-2023 |
2,12 % | Fairmount Funds Management LLC | 5.929.592 | 0 | 31-12-2023 |
2,03 % | Pentwater Capital Management LP | 5.662.500 | 5.662.500 | 31-12-2023 |
1,98 % | Norges Bank Investment Management (NBIM) | 5.539.334 | 5.424.434 | 31-12-2023 |
1,93 % | Geode Capital Management, L.L.C. | 5.382.875 | 482.900 | 31-12-2023 |
1,92 % | Fidelity Investments Canada ULC | 5.360.000 | 5.360.000 | 31-12-2023 |
1,62 % | D. E. Shaw & Co., L.P. | 4.522.797 | -2.472.442 | 31-12-2023 |
1,60 % | Millennium Management LLC | 4.473.868 | 2.868.154 | 31-12-2023 |
1,15 % | Voloridge Investment Management, LLC | 3.221.231 | 708.980 | 31-12-2023 |
1,06 % | Boxer Capital, L.L.C. | 2.961.000 | 0 | 31-12-2023 |
1,05 % | Emerald Advisers LLC | 2.933.190 | -344.179 | 31-12-2023 |
0,89 % | Maverick Capital, Ltd. | 2.493.217 | -25.310 | 31-12-2023 |
0,83 % | TIG Advisors, L.L.C. | 2.313.670 | 2.313.670 | 31-12-2023 |
0,79 % | Morgan Stanley & Co. LLC | 2.209.536 | 64.583 | 31-12-2023 |
0,79 % | Tang Capital Management, LLC | 2.199.137 | 699.137 | 31-12-2023 |
0,76 % | Medical Strategy GmbH | 2.126.763 | 0 | 30-9-2023 |
0,74 % | Northern Trust Investments, Inc. | 2.072.998 | 62.196 | 31-12-2023 |
0,73 % | Nuveen LLC | 2.041.214 | -845.027 | 31-12-2023 |
0,73 % | Kryger Capital Limited | 2.036.155 | 2.036.155 | 31-12-2023 |
0,70 % | Wellington Management Company, LLP | 1.954.413 | -11.304.584 | 31-12-2023 |
0,68 % | Charles Schwab Investment Management, Inc. | 1.892.446 | 61.871 | 31-12-2023 |
0,65 % | Avidity Partners Management LP | 1.829.215 | -88.692 | 31-12-2023 |
0,64 % | HOOPP Investment Management | 1.785.296 | 1.485.296 | 31-12-2023 |
0,63 % | Alpine Associates Management Inc. | 1.761.300 | 1.749.300 | 31-12-2023 |
0,58 % | Renaissance Technologies LLC | 1.631.240 | 896.600 | 31-12-2023 |
0,58 % | Magnetar Capital Partners LP | 1.629.285 | 1.629.285 | 31-12-2023 |
0,55 % | Sofinnova Investments, Inc | 1.546.902 | -498.300 | 31-12-2023 |
0,54 % | AllianceBernstein L.P. | 1.507.809 | 1.207.295 | 31-12-2023 |
0,54 % | AQR Capital Management, LLC | 1.506.601 | 1.380.964 | 31-12-2023 |
0,54 % | Balyasny Asset Management LP | 1.496.758 | 1.484.838 | 31-12-2023 |
0,53 % | Morgan Stanley Investment Management Inc. (US) | 1.487.210 | -544.787 | 31-12-2023 |
0,51 % | Gabelli Funds, LLC | 1.422.804 | 1.422.804 | 31-12-2023 |
0,51 % | Kynam Capital Management LP | 1.422.503 | 1.422.503 | 31-12-2023 |
0,50 % | Affinity Asset Advisors LLC | 1.404.608 | 1.404.608 | 31-12-2023 |
0,49 % | QVT Financial LP | 1.375.900 | 0 | 31-12-2023 |
0,49 % | Westchester Capital Management, LLC | 1.364.927 | 1.364.927 | 31-12-2023 |
0,45 % | J.P. Morgan Securities LLC | 1.265.347 | 28.617 | 31-12-2023 |
0,45 % | BlackRock Financial Management, Inc. | 1.243.147 | -259.980 | 31-12-2023 |
0,42 % | Marshall Wace LLP | 1.187.027 | 1.187.027 | 31-12-2023 |
0,42 % | Artisan Partners Limited Partnership | 1.172.323 | -2.552.260 | 31-12-2023 |
0,40 % | Principal Global Investors (Equity) | 1.127.402 | 142.738 | 31-12-2023 |
0,40 % | Candriam Belgium S.A. | 1.122.598 | 10 | 31-12-2023 |
0,40 % | Candriam Luxembourg S.A. | 1.122.557 | 0 | 31-12-2023 |
0,36 % | Pinnacle Associates Ltd. | 1.011.792 | -4.364 | 31-12-2023 |
0,35 % | Pictet Asset Management Ltd. | 975.962 | -2.732.177 | 31-12-2023 |
0,35 % | Adage Capital Management, L.P. | 971.928 | 771.928 | 31-12-2023 |
0,35 % | BlackRock Advisors (UK) Limited | 971.070 | 19.799 | 31-1-2024 |
0,34 % | T. Rowe Price Associates, Inc. | 963.620 | -2.811.554 | 31-12-2023 |
0,34 % | Lombard Odier Asset Management (Europe) Ltd | 947.497 | -36.199 | 30-9-2022 |
0,32 % | BlackRock Asset Management Ireland Limited | 902.926 | -16.784 | 31-12-2023 |
0,32 % | Water Island Capital, LLC | 893.758 | 304.893 | 31-12-2023 |
0,32 % | Two Sigma Investments, LP | 887.018 | -2.035.717 | 31-12-2023 |
0,31 % | Avoro Capital Advisors LLC | 875.000 | 875.000 | 31-12-2023 |
0,30 % | Farallon Capital Management, L.L.C. | 842.000 | 842.000 | 31-12-2023 |
0,30 % | American Century Investment Management, Inc. | 836.134 | 137.018 | 31-12-2023 |
0,29 % | Goldman Sachs & Company, Inc. | 809.254 | -64.684 | 31-12-2023 |
0,28 % | Citadel Advisors LLC | 795.458 | -492.084 | 31-12-2023 |
0,27 % | Eventide Asset Management, LLC | 763.000 | -537.000 | 31-12-2023 |
0,27 % | Rock Springs Capital Management LP | 759.365 | 0 | 31-12-2023 |
0,27 % | BofA Global Research (US) | 755.774 | 270.386 | 31-12-2023 |
0,27 % | DWS Investments UK Limited | 751.326 | 630.590 | 31-12-2023 |
0,27 % | Eversept Partners, LP | 748.950 | 748.950 | 31-12-2023 |
0,26 % | Susquehanna International Group, LLP | 736.034 | -238.853 | 31-12-2023 |
0,26 % | AQR Arbitrage, LLC | 719.919 | 719.919 | 31-12-2023 |
0,24 % | IndexIQ Advisors LLC | 682.396 | 682.396 | 31-12-2023 |
0,24 % | Voya Investment Management LLC | 669.351 | 154.215 | 31-12-2023 |
0,24 % | BlackRock Investment Management, LLC | 661.835 | -13.096 | 31-12-2023 |
0,24 % | Decheng Capital LLC | 659.928 | 244.048 | 31-12-2023 |
0,24 % | BNY Mellon Asset Management | 659.833 | -30.822 | 31-12-2023 |
0,23 % | Sio Capital Management, LLC | 644.366 | 411.615 | 31-12-2023 |
0,23 % | Barclays Bank PLC | 640.777 | 302.253 | 31-12-2023 |
0,23 % | Jane Street Capital, L.L.C. | 634.353 | -283.411 | 31-12-2023 |
0,21 % | Superstring Capital Management LP | 598.072 | 598.072 | 31-12-2023 |
0,21 % | First Trust Capital Management L.P. | 596.720 | 596.720 | 31-12-2023 |
0,21 % | CPP Investment Board | 586.990 | 586.990 | 31-12-2023 |
0,20 % | Baillie Gifford & Co. | 566.529 | 0 | 31-10-2023 |
0,19 % | Melqart Asset Management (UK) Limited | 531.324 | 531.324 | 31-12-2023 |
0,19 % | HSBC Global Asset Management (UK) Limited | 519.779 | 519.779 | 31-12-2023 |
0,18 % | Invesco Capital Management LLC | 515.275 | 174.614 | 31-12-2023 |
0,18 % | Picton Mahoney Asset Management | 500.000 | 500.000 | 31-12-2023 |
0,18 % | CM Management, LLC | 500.000 | 0 | 31-12-2023 |
0,17 % | JPMorgan Private Bank (United States) | 482.994 | -20.174 | 31-12-2023 |
0,17 % | Schweizerische Nationalbank | 480.800 | 0 | 31-12-2023 |
0,17 % | Carlson Capital, L.P. | 466.188 | 466.188 | 31-12-2023 |
0,16 % | Slotnik Capital, LLC | 460.000 | 460.000 | 31-12-2023 |
0,16 % | Dimensional Fund Advisors, L.P. | 454.213 | -726.531 | 31-12-2023 |
0,16 % | Fidelity Management & Research Company LLC | 453.168 | -5.326.775 | 31-12-2023 |
0,15 % | Credit Suisse Funds AG | 417.277 | 128.166 | 31-12-2023 |
0,15 % | Segantii Capital Management Limited | 415.000 | 415.000 | 31-12-2023 |
0,15 % | PanAgora Asset Management Inc. | 409.658 | -688.759 | 31-12-2023 |
0,14 % | Woodline Partners LP | 400.000 | -2.033.161 | 31-12-2023 |
0,14 % | GLG LLC | 388.103 | 374.005 | 31-12-2023 |
0,14 % | Mellon Investments Corporation | 382.594 | -482.140 | 31-12-2023 |
0,13 % | Pictet Asset Management (Japan) Ltd. | 372.310 | 372.310 | 31-10-2023 |
0,13 % | Invesco Advisers, Inc. | 370.048 | -375.459 | 31-12-2023 |