4,42 % | BlackRock Institutional Trust Company, N.A. | 16.974.342 | 442.348 | 31/12/2023 |
3,80 % | State Street Global Advisors (US) | 14.623.723 | 672.447 | 31/12/2023 |
2,99 % | Langer (Robert S Jr.) | 11.509.357 | 0 | 7/3/2024 |
2,51 % | Flagship Ventures | 9.666.038 | 0 | 7/3/2024 |
2,35 % | Boston Biotech Ventures, L.L.C. | 9.050.372 | 0 | 7/3/2024 |
11,88 % | Baillie Gifford & Co. | 45.654.527 | 5.344 | 31/12/2023 |
10,16 % | The Vanguard Group, Inc. | 39.036.765 | 5.275.392 | 28/3/2024 |
1,91 % | Theleme Partners LLP | 7.349.456 | 451.844 | 31/12/2023 |
1,88 % | Wellington Management Company, LLP | 7.225.579 | 1.614.460 | 31/12/2023 |
1,87 % | Invesco Capital Management (QQQ Trust) | 7.178.424 | -15.597 | 31/3/2024 |
1,71 % | OCHA, L.L.C. | 6.564.880 | 0 | 7/3/2024 |
1,70 % | Geode Capital Management, L.L.C. | 6.549.461 | 134.452 | 31/12/2023 |
1,60 % | Fidelity Management & Research Company LLC | 6.166.336 | 2.325.236 | 31/12/2023 |
1,42 % | Bancel (Stephane J) | 5.460.224 | 0 | 7/3/2024 |
0,94 % | Capital World Investors | 3.629.389 | -338.342 | 31/12/2023 |
0,92 % | Manulife Investment Management (North America) Limited | 3.542.967 | -333.180 | 31/12/2023 |
0,91 % | Norges Bank Investment Management (NBIM) | 3.494.874 | -3.393 | 31/12/2023 |
0,85 % | Coatue Management, L.L.C. | 3.273.052 | -1.636.526 | 31/12/2023 |
0,82 % | Banque Pictet & Cie S.A. | 3.134.229 | -9.198 | 31/12/2023 |
0,74 % | Legal & General Investment Management Ltd. | 2.830.894 | 459.120 | 31/12/2023 |
0,72 % | Capital Research Global Investors | 2.760.948 | 23.296 | 31/3/2024 |
0,66 % | BlackRock Asset Management Ireland Limited | 2.538.933 | 19.319 | 31/12/2023 |
0,64 % | Invesco Capital Management LLC | 2.441.106 | -263.350 | 31/12/2023 |
0,54 % | Northern Trust Investments, Inc. | 2.085.285 | 23.661 | 31/12/2023 |
0,54 % | Afeyan (Noubar Boghos) | 2.056.931 | -45.000 | 17/4/2024 |
0,52 % | Morgan Stanley & Co. LLC | 2.015.130 | -725.471 | 31/12/2023 |
0,50 % | Baillie Gifford Overseas Ltd. | 1.917.148 | -65.547 | 29/2/2024 |
0,50 % | Bellevue Asset Management AG | 1.908.420 | 413.095 | 31/12/2023 |
0,49 % | Charles Schwab Investment Management, Inc. | 1.871.399 | 70.368 | 31/12/2023 |
0,47 % | Pictet Asset Management Ltd. | 1.797.450 | 407.441 | 31/12/2023 |
0,47 % | Mawer Investment Management Ltd. | 1.795.949 | -25.399 | 31/12/2023 |
0,43 % | Hoge (Stephen) | 1.642.290 | -15.000 | 15/4/2024 |
0,42 % | Goldman Sachs Bank AG | 1.612.759 | 169.386 | 31/12/2023 |
0,40 % | Sumitomo Mitsui Trust Bank, Limited | 1.545.829 | 463.960 | 31/3/2024 |
0,39 % | BlackRock Financial Management, Inc. | 1.500.372 | 92.337 | 31/12/2023 |
0,39 % | Goldman Sachs & Company, Inc. | 1.491.182 | 453.722 | 31/12/2023 |
0,38 % | BlackRock Investment Management (UK) Ltd. | 1.469.975 | -169.470 | 31/12/2023 |
0,37 % | Goldman Sachs Asset Management, L.P. | 1.423.814 | -172.089 | 31/12/2023 |
0,34 % | Dimensional Fund Advisors, L.P. | 1.307.164 | -530.849 | 31/12/2023 |
0,34 % | Mellon Investments Corporation | 1.297.913 | -89.097 | 31/12/2023 |
0,33 % | JP Morgan Asset Management | 1.276.847 | -165.162 | 31/12/2023 |
0,32 % | ARK Investment Management LLC | 1.217.383 | 779.980 | 31/3/2024 |
0,32 % | UBS Asset Management (Switzerland) | 1.213.379 | 168.975 | 31/12/2023 |
0,26 % | Schweizerische Nationalbank | 1.011.600 | -30.700 | 31/12/2023 |
0,25 % | BNY Mellon Asset Management | 967.232 | 20.005 | 31/12/2023 |
0,24 % | UBS Asset Management (Americas), Inc. | 931.928 | 250.648 | 31/12/2023 |
0,24 % | Nuveen LLC | 907.435 | -50.202 | 31/12/2023 |
0,23 % | Parametric Portfolio Associates LLC | 896.385 | -52.804 | 31/12/2023 |
0,23 % | First Trust Advisors L.P. | 893.316 | 102.251 | 31/12/2023 |
0,23 % | Barclays Bank PLC | 887.398 | 244.923 | 31/12/2023 |
0,22 % | Morgan Stanley Smith Barney LLC | 854.829 | -136.227 | 31/12/2023 |
0,22 % | Mitsubishi UFJ Trust and Banking Corporation | 843.632 | -67.536 | 31/12/2023 |
0,22 % | UBS Asset Management (UK) Ltd. | 839.823 | 142.435 | 31/12/2023 |
0,21 % | UBS Financial Services, Inc. | 809.587 | -144.578 | 31/12/2023 |
0,19 % | DWS Investments UK Limited | 748.693 | 299.806 | 31/12/2023 |
0,19 % | JPMorgan Asset Management U.K. Limited | 720.874 | -4.521 | 31/12/2023 |
0,19 % | Amundi Asset Management, SAS | 716.476 | 201.050 | 31/12/2023 |
0,19 % | National Pension Service | 712.056 | 19.961 | 31/12/2023 |
0,18 % | Jane Street Capital, L.L.C. | 696.018 | 334.530 | 31/12/2023 |
0,18 % | BNP Paribas Securities Corp. North America | 691.655 | 33.374 | 31/12/2023 |
0,17 % | T. Rowe Price Associates, Inc. | 659.403 | -394.341 | 31/12/2023 |
0,17 % | BlackRock (Netherlands) B.V. | 656.425 | 11.793 | 31/12/2023 |
0,16 % | HSBC Global Asset Management (UK) Limited | 630.404 | 892 | 31/12/2023 |
0,16 % | Northern Trust Global Investments | 625.448 | 92.500 | 31/12/2023 |
0,16 % | Assetmark, Inc. | 619.152 | 403.428 | 31/12/2023 |
0,16 % | Capital International Investors | 613.850 | -7 | 31/12/2023 |
0,16 % | Olayan Investments Company Establishment | 600.000 | 600.000 | 31/12/2023 |
0,15 % | California Public Employees' Retirement System | 591.073 | -19.766 | 31/12/2023 |
0,15 % | BlackRock Japan Co., Ltd. | 589.252 | 32.279 | 31/12/2023 |
0,15 % | Rhumbline Advisers Ltd. Partnership | 584.131 | -3.281 | 31/12/2023 |
0,15 % | Credit Suisse Funds AG | 578.702 | -24.567 | 31/12/2023 |
0,14 % | Citadel Advisors LLC | 541.016 | 35.601 | 31/12/2023 |
0,14 % | BlackRock Investment Management, LLC | 535.543 | 5.131 | 31/12/2023 |
0,14 % | Pictet & Cie (Europe) S.A. | 523.626 | 29.338 | 31/12/2023 |
0,13 % | California State Teachers Retirement System | 518.224 | -346 | 31/12/2023 |
0,13 % | Citi Investment Research (US) | 502.470 | -176.908 | 31/12/2023 |
0,12 % | Sagan (Paul L) | 462.513 | 0 | 7/3/2024 |
0,12 % | Voya Investment Management LLC | 459.871 | 149.929 | 31/12/2023 |
0,12 % | BofA Global Research (US) | 456.003 | -207.684 | 31/12/2023 |
0,12 % | New York State Common Retirement Fund | 455.407 | -37.691 | 31/12/2023 |
0,12 % | Matrix Capital Management Company, LP | 454.000 | 454.000 | 31/12/2023 |
0,12 % | Pictet Asset Management (Japan) Ltd. | 452.349 | 78.103 | 31/10/2023 |
0,12 % | T. Rowe Price International Ltd | 448.092 | 6.798 | 31/12/2023 |
0,11 % | Invesco Advisers, Inc. | 440.587 | 45.496 | 31/12/2023 |
0,11 % | Susquehanna International Group, LLP | 439.606 | 107.579 | 31/12/2023 |
0,11 % | AllianceBernstein L.P. | 416.626 | -28.598 | 31/12/2023 |
0,11 % | Grantham Mayo Van Otterloo & Co LLC | 411.846 | 105.431 | 31/12/2023 |
0,11 % | Mirae Asset Global Investments (USA) LLC | 408.090 | -1.333 | 31/12/2023 |
0,10 % | BMO Capital Markets (US) | 400.617 | 178.641 | 31/12/2023 |
0,10 % | Douglas C. Lane & Associates | 393.039 | 56.901 | 31/3/2024 |
0,10 % | Candriam Luxembourg S.A. | 389.205 | 25.174 | 29/2/2024 |
0,10 % | Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 386.741 | 23.288 | 31/12/2023 |
0,10 % | RBC Capital Markets Wealth Management | 380.093 | 74.145 | 31/12/2023 |
0,10 % | Florida State Board of Administration | 376.117 | 8.409 | 31/12/2023 |
0,10 % | CPP Investment Board | 372.158 | 2.402 | 31/12/2023 |
0,10 % | JPMorgan Private Bank (United States) | 371.426 | 103.801 | 31/12/2023 |
0,10 % | Royal London Asset Management Ltd. | 367.615 | 8.542 | 31/12/2023 |
0,10 % | ProShare Advisors LLC | 366.604 | -61.975 | 31/12/2023 |
0,09 % | Candriam Belgium S.A. | 363.044 | -79.316 | 31/12/2023 |
0,09 % | D. E. Shaw & Co., L.P. | 362.177 | 303.845 | 31/12/2023 |