| 7,75 % | T. Rowe Price Associates, Inc. | 4 167 909 | 403 654 | 2023. 12. 31. |
| 6,51 % | Scully (William P) | 3 502 481 | 1 039 481 | 2024. 02. 05. |
| 6,01 % | BlackRock Institutional Trust Company, N.A. | 3 232 512 | 357 674 | 2023. 12. 31. |
| 5,84 % | Fennell (Todd W.) | 3 141 459 | 3 141 459 | 2024. 02. 05. |
| 5,13 % | State Street Global Advisors (US) | 2 758 564 | 648 331 | 2023. 12. 31. |
| 4,82 % | Wellington Management Company, LLP | 2 594 102 | 452 455 | 2023. 12. 31. |
| 3,79 % | Janus Henderson Investors | 2 035 984 | 209 375 | 2023. 12. 31. |
| 3,09 % | Palo Alto Investors LP | 1 660 057 | 2599 | 2023. 12. 31. |
| 21,54 % | EcoR1 Capital, LLC | 11 584 280 | 0 | 2023. 12. 31. |
| 2,02 % | First Light Asset Management, LLC | 1 088 801 | -405 238 | 2023. 12. 31. |
| 14,97 % | Fidelity Management & Research Company LLC | 8 049 620 | 19 506 | 2023. 12. 31. |
| 1,97 % | The Vanguard Group, Inc. | 1 061 850 | 38 191 | 2023. 12. 31. |
| 1,68 % | Geode Capital Management, L.L.C. | 905 125 | 46 065 | 2023. 12. 31. |
| 1,61 % | Dimensional Fund Advisors, L.P. | 867 635 | -235 227 | 2023. 12. 31. |
| 1,24 % | Boxer Capital, L.L.C. | 665 000 | 40 000 | 2023. 12. 31. |
| 1,16 % | Rock Springs Capital Management LP | 625 048 | 10 750 | 2023. 12. 31. |
| 0,93 % | Invus Public Equities Advisors, LLC | 501 360 | 501 360 | 2023. 12. 31. |
| 0,83 % | Eventide Asset Management, LLC | 445 155 | 0 | 2023. 12. 31. |
| 0,78 % | Granahan Investment Management, LLC | 417 157 | 69 092 | 2023. 12. 31. |
| 0,69 % | Maple Rock Capital Partners, Inc. | 373 584 | 139 000 | 2023. 12. 31. |
| 0,65 % | Morgan Stanley & Co. LLC | 349 838 | 147 440 | 2023. 12. 31. |
| 0,65 % | Finepoint Capital LP | 349 300 | 0 | 2023. 12. 31. |
| 0,65 % | Northern Trust Investments, Inc. | 349 274 | -2196 | 2023. 12. 31. |
| 0,62 % | Renaissance Technologies LLC | 335 800 | 75 200 | 2023. 12. 31. |
| 0,58 % | Charles Schwab Investment Management, Inc. | 313 230 | 4693 | 2023. 12. 31. |
| 0,56 % | Nuveen LLC | 299 397 | -128 073 | 2023. 12. 31. |
| 0,55 % | JP Morgan Asset Management | 295 440 | -10 124 | 2023. 12. 31. |
| 0,52 % | Armistice Capital LLC | 278 000 | 278 000 | 2023. 12. 31. |
| 0,52 % | BofA Global Research (US) | 277 828 | 177 954 | 2023. 12. 31. |
| 0,51 % | Goldman Sachs & Company, Inc. | 276 571 | 83 778 | 2023. 12. 31. |
| 0,48 % | Mellon Investments Corporation | 260 634 | -44 776 | 2023. 12. 31. |
| 0,46 % | BlackRock Financial Management, Inc. | 249 390 | -68 629 | 2023. 12. 31. |
| 0,43 % | Prosight Capital | 229 539 | 103 337 | 2023. 12. 31. |
| 0,39 % | Rafferty Asset Management LLC | 207 419 | 50 579 | 2023. 12. 31. |
| 0,38 % | Qube Research & Technologies Ltd | 203 682 | 119 029 | 2023. 12. 31. |
| 0,38 % | UBS Asset Management (Switzerland) | 202 090 | 25 737 | 2023. 12. 31. |
| 0,35 % | PFM Health Sciences, LP | 189 744 | -646 827 | 2023. 12. 31. |
| 0,34 % | Jane Street Capital, L.L.C. | 185 195 | 178 939 | 2023. 12. 31. |
| 0,33 % | Mariner Wealth Advisors | 178 424 | 10 492 | 2023. 12. 31. |
| 0,32 % | Birchview Capital, LP | 169 574 | 0 | 2023. 12. 31. |
| 0,31 % | Amundi Asset Management US, Inc. | 166 631 | -7160 | 2023. 12. 31. |
| 0,29 % | Connor, Clark & Lunn Investment Management Ltd. | 155 942 | 28 167 | 2023. 12. 31. |
| 0,28 % | Systematic Financial Management, L.P. | 149 759 | 130 009 | 2023. 12. 31. |
| 0,27 % | Two Sigma Investments, LP | 146 800 | -193 203 | 2023. 12. 31. |
| 0,27 % | TD Asset Management Inc. | 146 538 | -26 144 | 2023. 12. 31. |
| 0,26 % | Barclays Bank PLC | 142 053 | 56 572 | 2023. 12. 31. |
| 0,26 % | Citadel Advisors LLC | 138 587 | -10 348 | 2023. 12. 31. |
| 0,25 % | SG Americas Securities, L.L.C. | 135 857 | 43 363 | 2023. 12. 31. |
| 0,25 % | UBS Financial Services, Inc. | 132 497 | 87 245 | 2023. 12. 31. |
| 0,23 % | Pinnacle Associates Ltd. | 125 747 | 741 | 2023. 12. 31. |
| 0,23 % | BNY Mellon Asset Management | 122 456 | -4112 | 2023. 12. 31. |
| 0,22 % | AXA Investment Managers UK Ltd. | 120 617 | 7704 | 2023. 12. 31. |
| 0,22 % | BlackRock Advisors (UK) Limited | 115 984 | 3518 | 2024. 03. 31. |
| 0,21 % | BlackRock Investment Management, LLC | 111 084 | 2782 | 2023. 12. 31. |
| 0,19 % | Norges Bank Investment Management (NBIM) | 104 564 | 45 305 | 2023. 12. 31. |
| 0,17 % | BNP Paribas Securities Corp. North America | 93 004 | -12 212 | 2023. 12. 31. |
| 0,17 % | BlackRock Asset Management Ireland Limited | 89 518 | 13 157 | 2023. 12. 31. |
| 0,16 % | Citi Investment Research (US) | 87 581 | 19 651 | 2023. 12. 31. |
| 0,16 % | Manulife Investment Management (North America) Limited | 85 622 | 3591 | 2023. 12. 31. |
| 0,16 % | DCF Advisers, LLC | 84 000 | 1050 | 2023. 12. 31. |
| 0,15 % | Candriam Luxembourg S.A. | 82 000 | 0 | 2024. 02. 29. |
| 0,15 % | Ensign Peak Advisors, Inc. | 80 834 | -45 388 | 2023. 12. 31. |
| 0,15 % | Schweizerische Nationalbank | 79 200 | -7800 | 2023. 12. 31. |
| 0,14 % | Morgan Stanley Smith Barney LLC | 76 391 | 63 265 | 2023. 12. 31. |
| 0,14 % | Squarepoint Capital LLP | 74 030 | 41 691 | 2023. 12. 31. |
| 0,13 % | T. Rowe Price International Ltd | 69 442 | 13 684 | 2023. 12. 31. |
| 0,13 % | UBS Asset Management (Americas), Inc. | 68 108 | -799 | 2023. 12. 31. |
| 0,13 % | Trexquant Investment LP | 67 683 | 10 840 | 2023. 12. 31. |
| 0,12 % | Putnam Investment Management, L.L.C. | 66 516 | 9903 | 2023. 12. 31. |
| 0,12 % | Rhumbline Advisers Ltd. Partnership | 61 920 | -531 | 2023. 12. 31. |
| 0,11 % | Handelsbanken Kapitalförvaltning AB | 61 400 | 2500 | 2023. 12. 31. |
| 0,11 % | Credit Suisse Funds AG | 59 304 | 8641 | 2023. 12. 31. |
| 0,11 % | TwinBeech Capital LP | 58 096 | 39 720 | 2023. 12. 31. |
| 0,11 % | Seven Eight Capital, LP | 56 946 | 56 946 | 2023. 12. 31. |
| 0,11 % | Pier Capital, LLC | 56 829 | -627 | 2023. 12. 31. |
| 0,10 % | Newton Investment Management North America, LLC | 55 886 | -6525 | 2023. 12. 31. |
| 0,10 % | Parametric Portfolio Associates LLC | 54 742 | 2731 | 2023. 12. 31. |
| 0,10 % | JPMorgan Private Bank (United States) | 54 417 | 33 992 | 2023. 12. 31. |
| 0,09 % | Edgestream Partners, L.P. | 50 522 | 50 522 | 2023. 12. 31. |
| 0,09 % | Goldman Sachs Asset Management, L.P. | 49 321 | -410 | 2023. 12. 31. |
| 0,09 % | Algert Global LLC | 49 258 | 21 258 | 2023. 12. 31. |
| 0,09 % | Northern Trust Global Investments | 48 018 | 2353 | 2023. 12. 31. |
| 0,09 % | Sectoral Asset Management Inc. | 46 777 | -125 630 | 2023. 12. 31. |
| 0,09 % | AllianceBernstein L.P. | 46 746 | 1000 | 2023. 12. 31. |
| 0,09 % | Voya Investment Management LLC | 46 262 | -44 449 | 2023. 12. 31. |
| 0,09 % | Caption Management, LLC | 45 892 | 45 892 | 2023. 12. 31. |
| 0,08 % | RBF Capital, LLC | 45 362 | -9000 | 2023. 12. 31. |
| 0,08 % | California State Teachers Retirement System | 42 710 | -1422 | 2023. 12. 31. |
| 0,08 % | Platinum Asset Management | 41 508 | 0 | 2023. 12. 31. |
| 0,07 % | Legal & General Investment Management Ltd. | 38 397 | -105 | 2023. 12. 31. |
| 0,07 % | Millennium Management LLC | 37 656 | -227 869 | 2023. 12. 31. |
| 0,07 % | Assenagon Asset Management S.A. | 36 730 | 2663 | 2024. 02. 29. |
| 0,07 % | Alps Advisors, Inc. | 36 530 | -2994 | 2023. 12. 31. |
| 0,07 % | Engineers Gate Manager, L.P. | 36 523 | 25 139 | 2023. 12. 31. |
| 0,07 % | Exome Asset Management LLC | 36 384 | 36 384 | 2023. 12. 31. |
| 0,07 % | BlackRock Investment Management (UK) Ltd. | 35 993 | -82 716 | 2023. 12. 31. |
| 0,07 % | Monarch Partners Asset Management LLC | 35 645 | 2285 | 2022. 12. 31. |
| 0,06 % | GSA Capital Partners LLP | 34 850 | 34 850 | 2023. 12. 31. |
| 0,06 % | Wells Fargo Advisors | 34 793 | 15 803 | 2023. 12. 31. |
| 0,06 % | Allianz Global Investors U.S. LLC_NLE | 34 790 | 0 | 2023. 09. 30. |
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