4,42 % | BlackRock Institutional Trust Company, N.A. | 16 974 342 | 442 348 | 2023. 12. 31. |
3,80 % | State Street Global Advisors (US) | 14 623 723 | 672 447 | 2023. 12. 31. |
2,99 % | Langer (Robert S Jr.) | 11 509 357 | 0 | 2024. 03. 07. |
2,51 % | Flagship Ventures | 9 666 038 | 0 | 2024. 03. 07. |
2,35 % | Boston Biotech Ventures, L.L.C. | 9 050 372 | 0 | 2024. 03. 07. |
11,88 % | Baillie Gifford & Co. | 45 654 527 | 5344 | 2023. 12. 31. |
10,16 % | The Vanguard Group, Inc. | 39 036 765 | 5 275 392 | 2024. 03. 28. |
1,91 % | Theleme Partners LLP | 7 349 456 | 451 844 | 2023. 12. 31. |
1,88 % | Wellington Management Company, LLP | 7 225 579 | 1 614 460 | 2023. 12. 31. |
1,87 % | Invesco Capital Management (QQQ Trust) | 7 178 424 | -15 597 | 2024. 03. 31. |
1,71 % | OCHA, L.L.C. | 6 564 880 | 0 | 2024. 03. 07. |
1,70 % | Geode Capital Management, L.L.C. | 6 549 461 | 134 452 | 2023. 12. 31. |
1,60 % | Fidelity Management & Research Company LLC | 6 166 336 | 2 325 236 | 2023. 12. 31. |
1,42 % | Bancel (Stephane J) | 5 460 224 | 0 | 2024. 03. 07. |
0,94 % | Capital World Investors | 3 629 389 | -338 342 | 2023. 12. 31. |
0,92 % | Manulife Investment Management (North America) Limited | 3 542 967 | -333 180 | 2023. 12. 31. |
0,91 % | Norges Bank Investment Management (NBIM) | 3 494 874 | -3393 | 2023. 12. 31. |
0,85 % | Coatue Management, L.L.C. | 3 273 052 | -1 636 526 | 2023. 12. 31. |
0,82 % | Banque Pictet & Cie S.A. | 3 134 229 | -9198 | 2023. 12. 31. |
0,74 % | Legal & General Investment Management Ltd. | 2 830 894 | 459 120 | 2023. 12. 31. |
0,72 % | Capital Research Global Investors | 2 760 948 | 23 296 | 2024. 03. 31. |
0,66 % | BlackRock Asset Management Ireland Limited | 2 538 933 | 19 319 | 2023. 12. 31. |
0,64 % | Invesco Capital Management LLC | 2 441 106 | -263 350 | 2023. 12. 31. |
0,54 % | Northern Trust Investments, Inc. | 2 085 285 | 23 661 | 2023. 12. 31. |
0,54 % | Afeyan (Noubar Boghos) | 2 056 931 | -45 000 | 2024. 04. 17. |
0,52 % | Morgan Stanley & Co. LLC | 2 015 130 | -725 471 | 2023. 12. 31. |
0,50 % | Baillie Gifford Overseas Ltd. | 1 917 148 | -65 547 | 2024. 02. 29. |
0,50 % | Bellevue Asset Management AG | 1 908 420 | 413 095 | 2023. 12. 31. |
0,49 % | Charles Schwab Investment Management, Inc. | 1 871 399 | 70 368 | 2023. 12. 31. |
0,47 % | Pictet Asset Management Ltd. | 1 797 450 | 407 441 | 2023. 12. 31. |
0,47 % | Mawer Investment Management Ltd. | 1 795 949 | -25 399 | 2023. 12. 31. |
0,43 % | Hoge (Stephen) | 1 642 290 | -15 000 | 2024. 04. 15. |
0,42 % | Goldman Sachs Bank AG | 1 612 759 | 169 386 | 2023. 12. 31. |
0,40 % | Sumitomo Mitsui Trust Bank, Limited | 1 545 829 | 463 960 | 2024. 03. 31. |
0,39 % | BlackRock Financial Management, Inc. | 1 500 372 | 92 337 | 2023. 12. 31. |
0,39 % | Goldman Sachs & Company, Inc. | 1 491 182 | 453 722 | 2023. 12. 31. |
0,38 % | BlackRock Investment Management (UK) Ltd. | 1 469 975 | -169 470 | 2023. 12. 31. |
0,37 % | Goldman Sachs Asset Management, L.P. | 1 423 814 | -172 089 | 2023. 12. 31. |
0,34 % | Dimensional Fund Advisors, L.P. | 1 307 164 | -530 849 | 2023. 12. 31. |
0,34 % | Mellon Investments Corporation | 1 297 913 | -89 097 | 2023. 12. 31. |
0,33 % | JP Morgan Asset Management | 1 276 847 | -165 162 | 2023. 12. 31. |
0,32 % | ARK Investment Management LLC | 1 217 383 | 779 980 | 2024. 03. 31. |
0,32 % | UBS Asset Management (Switzerland) | 1 213 379 | 168 975 | 2023. 12. 31. |
0,26 % | Schweizerische Nationalbank | 1 011 600 | -30 700 | 2023. 12. 31. |
0,25 % | BNY Mellon Asset Management | 967 232 | 20 005 | 2023. 12. 31. |
0,24 % | UBS Asset Management (Americas), Inc. | 931 928 | 250 648 | 2023. 12. 31. |
0,24 % | Nuveen LLC | 907 435 | -50 202 | 2023. 12. 31. |
0,23 % | Parametric Portfolio Associates LLC | 896 385 | -52 804 | 2023. 12. 31. |
0,23 % | First Trust Advisors L.P. | 893 316 | 102 251 | 2023. 12. 31. |
0,23 % | Barclays Bank PLC | 887 398 | 244 923 | 2023. 12. 31. |
0,22 % | Morgan Stanley Smith Barney LLC | 854 829 | -136 227 | 2023. 12. 31. |
0,22 % | Mitsubishi UFJ Trust and Banking Corporation | 843 632 | -67 536 | 2023. 12. 31. |
0,22 % | UBS Asset Management (UK) Ltd. | 839 823 | 142 435 | 2023. 12. 31. |
0,21 % | UBS Financial Services, Inc. | 809 587 | -144 578 | 2023. 12. 31. |
0,19 % | DWS Investments UK Limited | 748 693 | 299 806 | 2023. 12. 31. |
0,19 % | JPMorgan Asset Management U.K. Limited | 720 874 | -4521 | 2023. 12. 31. |
0,19 % | Amundi Asset Management, SAS | 716 476 | 201 050 | 2023. 12. 31. |
0,19 % | National Pension Service | 712 056 | 19 961 | 2023. 12. 31. |
0,18 % | Jane Street Capital, L.L.C. | 696 018 | 334 530 | 2023. 12. 31. |
0,18 % | BNP Paribas Securities Corp. North America | 691 655 | 33 374 | 2023. 12. 31. |
0,17 % | T. Rowe Price Associates, Inc. | 659 403 | -394 341 | 2023. 12. 31. |
0,17 % | BlackRock (Netherlands) B.V. | 656 425 | 11 793 | 2023. 12. 31. |
0,16 % | HSBC Global Asset Management (UK) Limited | 630 404 | 892 | 2023. 12. 31. |
0,16 % | Northern Trust Global Investments | 625 448 | 92 500 | 2023. 12. 31. |
0,16 % | Assetmark, Inc. | 619 152 | 403 428 | 2023. 12. 31. |
0,16 % | Capital International Investors | 613 850 | -7 | 2023. 12. 31. |
0,16 % | Olayan Investments Company Establishment | 600 000 | 600 000 | 2023. 12. 31. |
0,15 % | California Public Employees' Retirement System | 591 073 | -19 766 | 2023. 12. 31. |
0,15 % | BlackRock Japan Co., Ltd. | 589 252 | 32 279 | 2023. 12. 31. |
0,15 % | Rhumbline Advisers Ltd. Partnership | 584 131 | -3281 | 2023. 12. 31. |
0,15 % | Credit Suisse Funds AG | 578 702 | -24 567 | 2023. 12. 31. |
0,14 % | Citadel Advisors LLC | 541 016 | 35 601 | 2023. 12. 31. |
0,14 % | BlackRock Investment Management, LLC | 535 543 | 5131 | 2023. 12. 31. |
0,14 % | Pictet & Cie (Europe) S.A. | 523 626 | 29 338 | 2023. 12. 31. |
0,13 % | California State Teachers Retirement System | 518 224 | -346 | 2023. 12. 31. |
0,13 % | Citi Investment Research (US) | 502 470 | -176 908 | 2023. 12. 31. |
0,12 % | Sagan (Paul L) | 462 513 | 0 | 2024. 03. 07. |
0,12 % | Voya Investment Management LLC | 459 871 | 149 929 | 2023. 12. 31. |
0,12 % | BofA Global Research (US) | 456 003 | -207 684 | 2023. 12. 31. |
0,12 % | New York State Common Retirement Fund | 455 407 | -37 691 | 2023. 12. 31. |
0,12 % | Matrix Capital Management Company, LP | 454 000 | 454 000 | 2023. 12. 31. |
0,12 % | Pictet Asset Management (Japan) Ltd. | 452 349 | 78 103 | 2023. 10. 31. |
0,12 % | T. Rowe Price International Ltd | 448 092 | 6798 | 2023. 12. 31. |
0,11 % | Invesco Advisers, Inc. | 440 587 | 45 496 | 2023. 12. 31. |
0,11 % | Susquehanna International Group, LLP | 439 606 | 107 579 | 2023. 12. 31. |
0,11 % | AllianceBernstein L.P. | 416 626 | -28 598 | 2023. 12. 31. |
0,11 % | Grantham Mayo Van Otterloo & Co LLC | 411 846 | 105 431 | 2023. 12. 31. |
0,11 % | Mirae Asset Global Investments (USA) LLC | 408 090 | -1333 | 2023. 12. 31. |
0,10 % | BMO Capital Markets (US) | 400 617 | 178 641 | 2023. 12. 31. |
0,10 % | Douglas C. Lane & Associates | 393 039 | 56 901 | 2024. 03. 31. |
0,10 % | Candriam Luxembourg S.A. | 389 205 | 25 174 | 2024. 02. 29. |
0,10 % | Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 386 741 | 23 288 | 2023. 12. 31. |
0,10 % | RBC Capital Markets Wealth Management | 380 093 | 74 145 | 2023. 12. 31. |
0,10 % | Florida State Board of Administration | 376 117 | 8409 | 2023. 12. 31. |
0,10 % | CPP Investment Board | 372 158 | 2402 | 2023. 12. 31. |
0,10 % | JPMorgan Private Bank (United States) | 371 426 | 103 801 | 2023. 12. 31. |
0,10 % | Royal London Asset Management Ltd. | 367 615 | 8542 | 2023. 12. 31. |
0,10 % | ProShare Advisors LLC | 366 604 | -61 975 | 2023. 12. 31. |
0,09 % | Candriam Belgium S.A. | 363 044 | -79 316 | 2023. 12. 31. |
0,09 % | D. E. Shaw & Co., L.P. | 362 177 | 303 845 | 2023. 12. 31. |