| 7,98818 % | Atlas Venture | 8 020 136 | -46 534 | 2024. 03. 31. |
| 7,81411 % | Forbion Capital Partners | 7 845 364 | 1 714 285 | 2024. 03. 31. |
| 5,19289 % | RA Capital Management, LP | 5 213 661 | 5 213 661 | 2024. 03. 25. |
| 4,48207 % | Deep Track Capital LP | 4 500 000 | 2 500 000 | 2024. 01. 19. |
| 3,43755 % | MPM Capital Inc. | 3 451 303 | -1 500 000 | 2024. 02. 12. |
| 3,32220 % | BlackRock Institutional Trust Company, N.A. | 3 335 485 | 467 231 | 2023. 12. 31. |
| 3,04127 % | Citadel Advisors LLC | 3 053 440 | 11 834 | 2023. 12. 31. |
| 2,32783 % | State Street Global Advisors (US) | 2 337 141 | 398 499 | 2023. 12. 31. |
| 2,31429 % | The Vanguard Group, Inc. | 2 323 550 | -34 673 | 2023. 12. 31. |
| 2,16525 % | VR Adviser, LLC | 2 173 913 | 0 | 2023. 12. 31. |
| 2,00018 % | Morgan Stanley & Co. LLC | 2 008 178 | 1 917 463 | 2023. 12. 31. |
| 1,88773 % | Franklin Advisers, Inc. | 1 895 285 | 232 | 2023. 12. 31. |
| 1,87251 % | Logos Global Management LLC | 1 880 000 | -300 000 | 2023. 12. 31. |
| 1,64358 % | TCG Crossover Management, LLC | 1 650 150 | 0 | 2023. 12. 31. |
| 1,21311 % | Invus Public Equities Advisors, LLC | 1 217 960 | 402 875 | 2023. 12. 31. |
| 1,18012 % | Frazier Healthcare Partners | 1 184 840 | 1 184 840 | 2023. 12. 31. |
| 1,11048 % | Goldman Sachs & Company, Inc. | 1 114 918 | -352 426 | 2023. 12. 31. |
| 1,03101 % | Vivo Capital, LLC | 1 035 136 | 0 | 2023. 12. 31. |
| 1,00947 % | Sofinnova Investments, Inc | 1 013 505 | 328 372 | 2023. 12. 31. |
| 0,92912 % | Geode Capital Management, L.L.C. | 932 838 | 75 128 | 2023. 12. 31. |
| 0,92302 % | Fidelity Management & Research Company LLC | 926 712 | 80 352 | 2023. 12. 31. |
| 0,89641 % | Commodore Capital LP | 900 000 | 900 000 | 2023. 12. 31. |
| 0,82072 % | Armistice Capital LLC | 824 000 | -376 000 | 2023. 12. 31. |
| 0,80234 % | Dimensional Fund Advisors, L.P. | 805 551 | -137 657 | 2023. 12. 31. |
| 0,78979 % | Octagon Capital Advisors LP | 792 945 | 100 000 | 2023. 12. 31. |
| 0,76755 % | Candriam Luxembourg S.A. | 770 624 | -58 000 | 2024. 02. 29. |
| 0,76058 % | Candriam Belgium S.A. | 763 624 | 40 000 | 2023. 12. 31. |
| 0,75280 % | Braidwell LP | 755 811 | -1 066 161 | 2023. 12. 31. |
| 0,64023 % | Nantahala Capital Management, LLC | 642 789 | -40 375 | 2023. 12. 31. |
| 0,54813 % | AXA Investment Managers UK Ltd. | 550 324 | 74 298 | 2023. 12. 31. |
| 0,50926 % | Ensign Peak Advisors, Inc. | 511 293 | 0 | 2023. 12. 31. |
| 0,43379 % | Woodline Partners LP | 435 526 | 99 642 | 2023. 12. 31. |
| 0,41613 % | Wasatch Global Investors Inc | 417 794 | -1 266 723 | 2024. 03. 31. |
| 0,40588 % | VV Manager LLC | 407 499 | -1 667 288 | 2024. 03. 31. |
| 0,39841 % | Laurion Capital Management LP | 400 000 | 400 000 | 2023. 12. 31. |
| 0,38765 % | Point72 Asset Management, L.P. | 389 200 | -186 600 | 2023. 12. 31. |
| 0,38654 % | Millennium Management LLC | 388 090 | 388 090 | 2023. 12. 31. |
| 0,38089 % | ArrowMark Colorado Holdings, LLC | 382 416 | 0 | 2023. 12. 31. |
| 0,37401 % | Northern Trust Investments, Inc. | 375 507 | 34 963 | 2023. 12. 31. |
| 0,37351 % | Federated Hermes Global Investment Management Corp. | 375 000 | 375 000 | 2023. 12. 31. |
| 0,35468 % | Fidelity Institutional Asset Management | 356 100 | 356 100 | 2023. 12. 31. |
| 0,33025 % | Charles Schwab Investment Management, Inc. | 331 568 | 6197 | 2023. 12. 31. |
| 0,28550 % | Assenagon Asset Management S.A. | 286 644 | -434 830 | 2023. 12. 31. |
| 0,28476 % | Ikarian Capital LLC | 285 900 | 285 900 | 2023. 12. 31. |
| 0,27900 % | AllianceBernstein L.P. | 280 114 | 29 128 | 2023. 12. 31. |
| 0,27460 % | Schonfeld Strategic Advisors LLC | 275 699 | 275 699 | 2023. 12. 31. |
| 0,25975 % | BlackRock Financial Management, Inc. | 260 785 | 3986 | 2023. 12. 31. |
| 0,20206 % | Jennison Associates LLC | 202 871 | 202 871 | 2023. 12. 31. |
| 0,18654 % | Caption Management, LLC | 187 288 | 187 288 | 2023. 12. 31. |
| 0,18610 % | Arctic Fund Management AS | 186 844 | -12 800 | 2024. 02. 29. |
| 0,16526 % | Allianz Global Investors GmbH | 165 920 | 144 600 | 2024. 01. 31. |
| 0,16339 % | Rafferty Asset Management LLC | 164 041 | 24 632 | 2023. 12. 31. |
| 0,16036 % | Algert Global LLC | 161 004 | 2291 | 2023. 12. 31. |
| 0,15274 % | Barclays Bank PLC | 153 351 | 53 777 | 2023. 12. 31. |
| 0,14996 % | Farwell (Wildon) | 150 560 | -12 536 | 2024. 03. 12. |
| 0,14729 % | Nuveen LLC | 147 876 | 0 | 2023. 12. 31. |
| 0,14725 % | Acuta Capital Partners, LLC | 147 836 | 1336 | 2023. 12. 31. |
| 0,14489 % | Wellington Management Company, LLP | 145 474 | 29 539 | 2023. 12. 31. |
| 0,13720 % | Schroder Investment Management Ltd. (SIM) | 137 751 | 137 751 | 2023. 12. 31. |
| 0,13720 % | International Biotechnology Trust PLC | 137 751 | -163 000 | 2023. 09. 30. |
| 0,12356 % | UBS Financial Services, Inc. | 124 050 | 69 892 | 2023. 12. 31. |
| 0,12211 % | BNY Mellon Asset Management | 122 602 | 11 396 | 2023. 12. 31. |
| 0,11881 % | Scalzo (Richard William) | 119 283 | -4945 | 2024. 03. 11. |
| 0,11792 % | BlackRock Investment Management, LLC | 118 395 | 1514 | 2023. 12. 31. |
| 0,10441 % | BlackRock Advisors (UK) Limited | 104 827 | 5446 | 2024. 03. 31. |
| 0,09695 % | Russell Investments Trust Company | 97 335 | -43 751 | 2023. 12. 31. |
| 0,08911 % | Stehman-Breen (Catherine) | 89 467 | 0 | 2024. 03. 31. |
| 0,08615 % | Raymond James & Associates, Inc. | 86 497 | -1741 | 2023. 12. 31. |
| 0,07977 % | Beskrovnaya (Oxana) | 80 094 | -4454 | 2024. 03. 11. |
| 0,07831 % | Group One Trading, L.P. | 78 620 | 18 286 | 2023. 12. 31. |
| 0,07593 % | Rhumbline Advisers Ltd. Partnership | 76 238 | 5667 | 2023. 12. 31. |
| 0,07132 % | Citi Investment Research (US) | 71 604 | 9709 | 2023. 12. 31. |
| 0,06189 % | Invesco Capital Management LLC | 62 142 | -21 448 | 2023. 12. 31. |
| 0,05996 % | Schweizerische Nationalbank | 60 200 | -3300 | 2023. 12. 31. |
| 0,05710 % | UBS O'Connor LLC | 57 330 | -53 422 | 2023. 12. 31. |
| 0,05697 % | Boothbay Fund Management, LLC | 57 200 | 57 200 | 2023. 12. 31. |
| 0,05427 % | Allianz Global Investors U.S. LLC_NLE | 54 485 | 0 | 2023. 09. 30. |
| 0,05341 % | Lubner (David Charles) | 53 625 | 0 | 2024. 03. 31. |
| 0,05313 % | Qube Research & Technologies Ltd | 53 344 | 53 344 | 2023. 12. 31. |
| 0,05128 % | Dimensional Fund Advisors, Ltd. | 51 489 | 0 | 2024. 01. 31. |
| 0,04660 % | Northern Trust Global Investments | 46 788 | 864 | 2023. 12. 31. |
| 0,04567 % | Goldman Sachs Asset Management, L.P. | 45 854 | 5056 | 2023. 12. 31. |
| 0,04175 % | Mellon Investments Corporation | 41 913 | 1733 | 2023. 12. 31. |
| 0,04062 % | BofA Global Research (US) | 40 782 | -52 979 | 2023. 12. 31. |
| 0,03984 % | Ostrum Asset Management | 40 000 | 40 000 | 2023. 12. 31. |
| 0,03984 % | Deka Vermögensmanagement GmbH | 40 000 | 0 | 2023. 12. 31. |
| 0,03938 % | Putnam Investment Management, L.L.C. | 39 536 | 2799 | 2023. 12. 31. |
| 0,03930 % | BlackRock Asset Management Ireland Limited | 39 453 | -7472 | 2023. 12. 31. |
| 0,03863 % | Voya Investment Management LLC | 38 782 | -33 165 | 2023. 12. 31. |
| 0,03788 % | Polen Capital Management, LLC | 38 028 | 0 | 2024. 02. 29. |
| 0,03772 % | SEI Investments Management Corporation | 37 869 | 15 683 | 2024. 03. 31. |
| 0,03461 % | Belvedere Trading, LLC | 34 744 | 18 686 | 2023. 12. 31. |
| 0,03433 % | California State Teachers Retirement System | 34 467 | -685 | 2023. 12. 31. |
| 0,03009 % | IndexIQ Advisors LLC | 30 210 | -696 | 2023. 12. 31. |
| 0,02931 % | JPMorgan Private Bank (United States) | 29 423 | 8560 | 2023. 12. 31. |
| 0,02727 % | Aperio Group, LLC | 27 379 | 16 458 | 2023. 12. 31. |
| 0,02685 % | ProFund Advisors LLC | 26 962 | 3169 | 2023. 12. 31. |
| 0,02675 % | Credit Suisse Funds AG | 26 858 | 0 | 2023. 12. 31. |
| 0,02591 % | Susquehanna International Group, LLP | 26 018 | -48 030 | 2023. 12. 31. |
| 0,02441 % | XTX Markets LLC | 24 511 | 24 511 | 2023. 12. 31. |
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