5.70 % | Adage Capital Management, L.P. | 5,398,825 | 2,879,568 | 9.2.2023 |
5.09 % | BlackRock Institutional Trust Company, N.A. | 4,823,128 | 487,993 | 31.12.2022 |
4.35 % | The Vanguard Group, Inc. | 4,124,924 | 528,638 | 31.12.2022 |
2.71 % | Leon (Francisco) | 2,573,000 | 0 | 13.2.2023 |
2.71 % | Palmer (Ashleigh) | 2,570,050 | 0 | 13.2.2023 |
12.53 % | Sessa Capital | 11,879,023 | -3,000,000 | 18.1.2023 |
1.64 % | State Street Global Advisors (US) | 1,558,238 | 263,813 | 31.12.2022 |
1.39 % | Geode Capital Management, L.L.C. | 1,322,189 | 125,392 | 31.12.2022 |
1.21 % | D. E. Shaw & Co., L.P. | 1,143,300 | 1,038,757 | 31.12.2022 |
1.18 % | VR Adviser, LLC | 1,118,653 | 0 | 31.12.2022 |
0.95 % | BioImpact Capital LLC | 898,483 | 158,139 | 31.12.2022 |
0.88 % | Verition Fund Management LLC | 838,716 | -28,449 | 31.12.2022 |
0.70 % | Two Sigma Investments, LP | 665,730 | 506,008 | 31.12.2022 |
0.58 % | 683 Capital Management LLC | 550,000 | 550,000 | 31.12.2022 |
0.57 % | Northern Trust Investments, Inc. | 538,434 | 41,127 | 31.12.2022 |
0.54 % | Invesco Capital Management LLC | 512,298 | 509,787 | 31.12.2022 |
0.45 % | Millennium Management LLC | 423,295 | 423,295 | 31.12.2022 |
0.43 % | Nuveen LLC | 411,306 | 29,409 | 31.12.2022 |
0.42 % | Ghost Tree Capital, LLC | 400,000 | 400,000 | 31.12.2022 |
0.41 % | Palo Alto Investors LP | 390,800 | 0 | 31.12.2022 |
0.37 % | BlackRock Advisors (UK) Limited | 352,214 | 2,658 | 28.2.2023 |
0.35 % | Medical Strategy GmbH | 334,200 | 0 | 30.9.2022 |
0.35 % | BlackRock Asset Management Ireland Limited | 333,685 | 21,052 | 31.12.2022 |
0.34 % | Banque Lombard Odier & Cie SA | 322,895 | 322,895 | 31.12.2022 |
0.34 % | Lombard Odier Asset Management (Europe) Ltd | 322,792 | 147,734 | 31.12.2022 |
0.33 % | Voloridge Investment Management, LLC | 310,693 | 310,693 | 31.12.2022 |
0.32 % | Schonfeld Strategic Advisors LLC | 306,546 | 306,546 | 31.12.2022 |
0.30 % | Advisory Research, Inc. | 288,707 | 53,707 | 31.12.2022 |
0.29 % | EAM Investors, LLC | 276,250 | 276,250 | 31.12.2022 |
0.28 % | Jane Street Capital, L.L.C. | 261,657 | 250,153 | 31.12.2022 |
0.25 % | Principal Global Investors (Equity) | 239,073 | 223,922 | 31.12.2022 |
0.24 % | Cubist Systematic Strategies, LLC | 229,409 | 131,483 | 31.12.2022 |
0.22 % | EAM Global Investors LLC | 209,856 | 209,856 | 31.12.2022 |
0.21 % | Morgan Stanley & Co. LLC | 195,233 | -136,881 | 31.12.2022 |
0.21 % | BNY Mellon Asset Management | 194,536 | 13,234 | 31.12.2022 |
0.20 % | Group One Trading, L.P. | 188,342 | 43,659 | 31.12.2022 |
0.20 % | Schweizerische Nationalbank | 187,100 | 60,200 | 31.12.2022 |
0.19 % | Cabot Wealth Management, Inc. | 184,271 | 184,271 | 31.12.2022 |
0.19 % | Rice Hall James & Associates, LLC | 181,980 | -39,621 | 31.12.2022 |
0.19 % | Monticello Wealth Management, LLC | 180,555 | 0 | 31.12.2022 |
0.19 % | Charles Schwab Investment Management, Inc. | 176,464 | 11,358 | 31.12.2022 |
0.18 % | BlackRock Financial Management, Inc. | 168,536 | -10,213 | 31.12.2022 |
0.17 % | BlackRock Investment Management, LLC | 163,214 | 5,947 | 31.12.2022 |
0.16 % | Sigma Planning Corporation | 153,790 | 100 | 31.12.2022 |
0.16 % | Parametric Portfolio Associates LLC | 152,168 | 139,464 | 31.12.2022 |
0.14 % | Goldman Sachs & Company, Inc. | 128,006 | -21,008 | 31.12.2022 |
0.12 % | Susquehanna International Group, LLP | 114,911 | -68,229 | 31.12.2022 |
0.11 % | Qube Research & Technologies Ltd | 101,371 | 101,371 | 31.12.2022 |
0.10 % | Candriam Belgium S.A. | 97,509 | -110,142 | 31.12.2022 |
0.10 % | California State Teachers Retirement System | 92,471 | 22,342 | 31.12.2022 |
0.10 % | AllianceBernstein L.P. | 91,600 | 0 | 31.12.2022 |
0.10 % | Goldman Sachs Asset Management, L.P. | 91,264 | 14,955 | 31.12.2022 |
0.09 % | Credit Suisse Asset Management | 89,768 | 54,558 | 31.12.2022 |
0.09 % | ClariVest Asset Management LLC | 84,966 | 84,966 | 31.12.2022 |
0.09 % | Rhumbline Advisers Ltd. Partnership | 81,291 | 6,427 | 31.12.2022 |
0.08 % | State of Wisconsin Investment Board | 77,662 | 67,520 | 31.12.2022 |
0.08 % | Dimensional Fund Advisors, L.P. | 76,109 | -472 | 31.12.2022 |
0.07 % | Ramos (Eleanor L) | 70,000 | 0 | 21.3.2022 |
0.07 % | Macquarie Investment Management | 70,000 | 0 | 31.12.2022 |
0.07 % | Polen Capital Management, LLC | 67,333 | 0 | 31.1.2023 |
0.07 % | Russell Investments Trust Company | 67,333 | 0 | 31.12.2022 |
0.07 % | Jump Financial, LLC | 67,074 | 67,074 | 31.12.2022 |
0.07 % | Northern Trust Global Investments | 64,280 | 2,401 | 31.12.2022 |
0.06 % | State Street Global Advisors Ireland Limited | 60,275 | 267 | 31.1.2023 |
0.06 % | Wells Fargo Advisors | 59,848 | 55,738 | 31.12.2022 |
0.06 % | Mackenzie Financial Corporation | 57,141 | 47,909 | 31.12.2022 |
0.05 % | Assenagon Asset Management S.A. | 52,053 | -2,059 | 28.2.2023 |
0.05 % | BofA Global Research (US) | 49,706 | -17,471 | 31.12.2022 |
0.05 % | Victory Capital Management Inc. | 49,640 | 49,640 | 31.12.2022 |
0.05 % | Simplex Trading, LLC | 49,380 | 13,447 | 31.12.2022 |
0.05 % | LPL Financial LLC | 47,783 | 17,900 | 31.12.2022 |
0.05 % | Squarepoint Capital LLP | 44,899 | 44,899 | 31.12.2022 |
0.05 % | UBS Financial Services, Inc. | 43,249 | 11,297 | 31.12.2022 |
0.05 % | Citadel Advisors LLC | 42,764 | -191,162 | 31.12.2022 |
0.04 % | UBS Asset Management (Switzerland) | 41,628 | 11,912 | 31.12.2022 |
0.04 % | BlackRock Investment Management (UK) Ltd. | 41,626 | 10,970 | 31.12.2022 |
0.04 % | Morgan Stanley Smith Barney LLC | 39,846 | 537 | 31.12.2022 |
0.04 % | Mellon Investments Corporation | 39,699 | 7,186 | 31.12.2022 |
0.04 % | Bluestone (Jeffrey Ph.D.) | 39,571 | 0 | 21.3.2022 |
0.04 % | JPMorgan Private Bank (United States) | 36,850 | 4,610 | 31.12.2022 |
0.04 % | New York State Common Retirement Fund | 34,909 | 7,701 | 31.12.2022 |
0.04 % | PGIM Quantitative Solutions LLC | 33,950 | 450 | 31.12.2022 |
0.03 % | Engineers Gate Manager, L.P. | 32,148 | 32,148 | 31.12.2022 |
0.03 % | Gotham Asset Management, LLC | 31,595 | 31,595 | 31.12.2022 |
0.03 % | T. Rowe Price International Ltd | 31,137 | 1,578 | 31.12.2022 |
0.03 % | LifeSci Index Partners, LLC | 31,095 | 0 | 28.2.2023 |
0.03 % | Virtus Etf Advisers LLC | 31,095 | 31,095 | 31.12.2022 |
0.03 % | MetLife Investment Management, LLC | 30,784 | 0 | 31.12.2022 |
0.03 % | Mirae Asset Global Investments (USA) LLC | 30,005 | 5,164 | 31.12.2022 |
0.03 % | Cambridge Investment Research Advisors, Inc. | 29,895 | 13,900 | 31.12.2022 |
0.03 % | SunAmerica Asset Management, LLC | 29,840 | 1,829 | 31.12.2022 |
0.03 % | Granite Investment Partners, LLC | 28,883 | -714 | 31.1.2023 |
0.03 % | Legal & General Investment Management Ltd. | 28,154 | 7,143 | 31.12.2022 |
0.03 % | Aperio Group, LLC | 27,795 | 18,993 | 31.12.2022 |
0.03 % | DWS Investments UK Limited | 27,484 | 4,538 | 31.12.2022 |
0.03 % | SEI Investments Management Corporation | 27,341 | 1,401 | 31.1.2023 |
0.03 % | UBS Asset Management (UK) Ltd. | 26,417 | 26,417 | 31.12.2022 |
0.03 % | Hightower Advisors, LLC | 25,820 | 2,205 | 31.12.2022 |
0.03 % | Barclays Bank PLC | 24,846 | 24,846 | 31.12.2022 |
0.03 % | Manulife Investment Management (North America) Limited | 24,740 | 354 | 31.12.2022 |