6.29399 % | BlackRock Institutional Trust Company, N.A. | 6,614,350 | 419,633 | 31.12.2023 |
5.47056 % | Millennium Management LLC | 5,749,015 | 736,732 | 19.3.2024 |
5.37149 % | Cadian Capital Management LP | 5,644,898 | 5,644,898 | 31.12.2023 |
5.01466 % | The Vanguard Group, Inc. | 5,269,902 | 243,261 | 31.12.2023 |
4.79908 % | Vitruvian Partners LLP | 5,043,356 | 0 | 31.12.2023 |
4.38738 % | Sofinnova Partners | 4,610,693 | -365,803 | 31.12.2022 |
2.78383 % | Morgan Stanley Investment Management Inc. (US) | 2,925,528 | 2,012,145 | 31.12.2023 |
2.62370 % | Portolan Capital Management, L.L.C. | 2,757,249 | 613,583 | 31.12.2023 |
2.49238 % | Fidelity Management & Research Company LLC | 2,619,243 | 2,616,840 | 31.12.2023 |
2.41423 % | MFS Investment Management | 2,537,114 | 584,372 | 31.12.2023 |
1.99495 % | Geode Capital Management, L.L.C. | 2,096,497 | 123,060 | 31.12.2023 |
1.84984 % | State Street Global Advisors (US) | 1,943,997 | 103,823 | 31.12.2023 |
1.79370 % | Blue Water Life Science Advisors, LP. | 1,885,000 | 0 | 31.12.2023 |
1.79023 % | Mudita Advisors LLP | 1,881,349 | 490,491 | 31.12.2023 |
1.66524 % | Canaccord Genuity Wealth Management | 1,750,000 | 0 | 31.12.2023 |
1.52250 % | Swedbank Robur Fonder AB | 1,600,000 | 0 | 29.2.2024 |
1.44509 % | River Global Investors LLP | 1,518,646 | 45,392 | 31.12.2023 |
1.35926 % | Granahan Investment Management, LLC | 1,428,449 | -547,398 | 31.12.2023 |
1.30724 % | ArrowMark Colorado Holdings, LLC | 1,373,777 | -1,035,261 | 31.12.2023 |
1.25676 % | Berenberg Bank (Asset Management) | 1,320,732 | -54,500 | 30.4.2023 |
1.22842 % | Columbia Threadneedle Investments (US) | 1,290,949 | 138,080 | 31.12.2023 |
0.97060 % | Chelverton Asset Management Ltd. | 1,020,000 | -30,000 | 31.12.2023 |
0.69810 % | Northern Trust Investments, Inc. | 733,632 | 19,568 | 31.12.2023 |
0.66130 % | Dimensional Fund Advisors, L.P. | 694,961 | 218,356 | 31.12.2023 |
0.63648 % | Silvercrest Asset Management Group LLC | 668,880 | -591,743 | 31.12.2023 |
0.62510 % | Grandeur Peak Global Advisors, LLC | 656,916 | -777,903 | 31.12.2023 |
0.56220 % | Crux Asset Management Limited | 590,820 | -28,000 | 29.2.2024 |
0.52336 % | Willis Investment Counsel Inc. | 550,000 | 550,000 | 31.12.2023 |
0.45184 % | Octopus Investments Limited | 474,835 | -70,000 | 29.2.2024 |
0.43007 % | North Run Capital, LP | 451,960 | -105,000 | 31.12.2022 |
0.42820 % | AWM Investment Company, Inc. | 450,000 | 450,000 | 31.12.2023 |
0.42428 % | Morgan Stanley & Co. LLC | 445,871 | 223,174 | 31.12.2023 |
0.38738 % | Fred Alger Management, LLC | 407,096 | 46,222 | 31.12.2023 |
0.36750 % | Roubaix Capital, LLC | 386,201 | 386,201 | 31.12.2023 |
0.35635 % | Mandell (Arthur M) | 374,484 | 0 | 31.3.2023 |
0.34935 % | Lazard Asset Management, L.L.C. | 367,132 | -90,236 | 31.12.2023 |
0.31706 % | Doerfler (Douglas A.) | 333,197 | 0 | 5.12.2023 |
0.31148 % | Royce Investment Partners | 327,338 | -95,222 | 31.12.2023 |
0.29307 % | Apollo Capital Management, L.P. | 307,987 | 0 | 31.12.2023 |
0.28641 % | Rathbones Investment Management Limited | 300,988 | -2,730 | 31.12.2023 |
0.27134 % | Allspring Global Investments, LLC | 285,146 | -5,406 | 31.3.2024 |
0.25363 % | BNY Mellon Asset Management | 266,538 | 42,459 | 31.12.2023 |
0.25247 % | BlackRock Financial Management, Inc. | 265,320 | 2,233 | 31.12.2023 |
0.24223 % | William Blair & Company, L.L.C. (Research) | 254,563 | 2,712 | 31.12.2023 |
0.23884 % | Jacobs Levy Equity Management, Inc. | 251,001 | 251,001 | 31.12.2023 |
0.23789 % | Bleichroeder LP | 250,000 | 0 | 31.12.2023 |
0.23654 % | BlackRock Investment Management, LLC | 248,581 | -6,763 | 31.12.2023 |
0.23575 % | Erck (Stanley C) | 247,751 | 0 | 31.3.2023 |
0.23376 % | Nuveen LLC | 245,655 | 0 | 31.12.2023 |
0.23194 % | Charles Schwab Investment Management, Inc. | 243,743 | 5,271 | 31.12.2023 |
0.20408 % | Fidelity Institutional Asset Management | 214,472 | 214,472 | 31.12.2023 |
0.18210 % | ARIAD Asset Management GmbH | 191,370 | 0 | 31.1.2024 |
0.17994 % | Renaissance Technologies LLC | 189,100 | -22,000 | 31.12.2023 |
0.16867 % | JPMorgan Private Bank (United States) | 177,259 | 123,676 | 31.12.2023 |
0.16639 % | Two Sigma Investments, LP | 174,860 | 174,860 | 31.12.2023 |
0.16510 % | Schweizerische Nationalbank | 173,500 | -16,900 | 31.12.2023 |
0.14037 % | BlackRock Advisors (UK) Limited | 147,520 | 4,849 | 31.3.2024 |
0.13821 % | BofA Global Research (US) | 145,249 | 64,352 | 31.12.2023 |
0.13697 % | Conestoga Capital Advisors, LLC | 143,945 | 0 | 29.2.2024 |
0.13481 % | UBS Asset Management (Americas), Inc. | 141,676 | 0 | 31.3.2023 |
0.13322 % | Toscafund Asset Management LLP | 140,000 | 0 | 30.6.2023 |
0.13080 % | Barclays Bank PLC | 137,460 | 106,266 | 31.12.2023 |
0.12954 % | Alberta Investment Management Corporation | 136,135 | -63,688 | 31.12.2023 |
0.12851 % | Citadel Advisors LLC | 135,055 | 86,981 | 31.12.2023 |
0.12642 % | Rhumbline Advisers Ltd. Partnership | 132,851 | 1,443 | 31.12.2023 |
0.12347 % | Goldman Sachs Asset Management, L.P. | 129,755 | 33,694 | 31.12.2023 |
0.12299 % | BlackRock Asset Management Ireland Limited | 129,250 | 8,896 | 31.12.2023 |
0.11474 % | Johnston (John Joseph) | 120,583 | 0 | 26.3.2024 |
0.10971 % | Mellon Investments Corporation | 115,295 | 0 | 31.12.2023 |
0.10948 % | Avantis Investors | 115,055 | 46,070 | 31.3.2024 |
0.10933 % | State Teachers Retirement System of Ohio | 114,900 | -6,300 | 31.12.2023 |
0.10598 % | Squarepoint Capital LLP | 111,375 | 111,375 | 31.12.2023 |
0.10430 % | Parametric Portfolio Associates LLC | 109,611 | -79,248 | 31.12.2023 |
0.09516 % | Lauxera Capital Partners | 100,000 | 0 | 31.1.2024 |
0.09516 % | Douglas (Richard H) | 100,000 | 80,000 | 31.3.2023 |
0.09094 % | UBS Financial Services, Inc. | 95,574 | 30,643 | 31.12.2023 |
0.08820 % | California State Teachers Retirement System | 92,693 | -4,004 | 31.12.2023 |
0.08764 % | UBS Asset Management (UK) Ltd. | 92,100 | 0 | 31.12.2023 |
0.08632 % | Columbia Threadneedle Management Limited | 90,718 | 1,147 | 31.12.2023 |
0.08308 % | Wilmington Trust Investment Advisors, Inc. | 87,304 | -76,058 | 31.12.2023 |
0.08006 % | American Century Investment Management, Inc. | 84,136 | -1,621,992 | 31.12.2023 |
0.07986 % | ValMark Advisers, Inc. | 83,927 | 83,927 | 31.12.2023 |
0.07731 % | Swirsky (Douglas J) | 81,250 | 81,250 | 15.3.2024 |
0.07701 % | Credit Suisse Funds AG | 80,934 | 11,573 | 31.12.2023 |
0.07691 % | Legal & General Investment Management Ltd. | 80,822 | 6,718 | 31.12.2023 |
0.06990 % | SEI Investments Management Corporation | 73,460 | -1,488 | 31.12.2023 |
0.06760 % | Assenagon Asset Management S.A. | 71,038 | 5,145 | 29.2.2024 |
0.06683 % | Citi Investment Research (US) | 70,228 | 11,170 | 31.12.2023 |
0.06594 % | Ohio Public Employees Retirement System | 69,300 | 69,300 | 31.12.2023 |
0.06534 % | Jane Street Capital, L.L.C. | 68,662 | 51,983 | 31.12.2023 |
0.06440 % | Goldman Sachs & Company, Inc. | 67,673 | -4,731 | 31.12.2023 |
0.06003 % | AllianceBernstein L.P. | 63,090 | -4,530 | 31.12.2023 |
0.05899 % | Ensign Peak Advisors, Inc. | 61,990 | 3,600 | 31.12.2023 |
0.05708 % | Aperio Group, LLC | 59,983 | 40,786 | 31.12.2023 |
0.05580 % | Northern Trust Global Investments | 58,645 | -764 | 31.12.2023 |
0.05473 % | Susquehanna International Group, LLP | 57,521 | 38,251 | 31.12.2023 |
0.05443 % | State Street Global Advisors Ireland Limited | 57,204 | -208 | 30.4.2023 |
0.05404 % | Chevy Chase Trust Company | 56,795 | 543 | 31.12.2023 |
0.05395 % | Gagnon Securities LLC | 56,701 | 1,264 | 31.12.2023 |
0.05364 % | Salem Investment Counselors, Inc. | 56,375 | 28,741 | 31.3.2024 |