Verastem Záväzky 2024

Čo robí Verastem?

Verastem Inc. is a biopharmaceutical company founded by Dr. Christoph Westphal in Cambridge, Massachusetts, in 2010. The company focuses on developing drugs for the treatment of cancer and other serious diseases using technologies based on small molecules and RNA interference. The company specializes in developing therapies for patients with particularly aggressive types of cancer, such as diffuse large B-cell lymphoma (DLBCL), mesothelial tumors, liver cancer, and pancreatic cancer. Verastem collaborates closely with leading academic research institutions and clinics around the world to test and validate the efficacy and safety of its therapies. Verastem's business model is based on identifying and developing drug candidates based on the needs of patients with serious diseases. The company uses patented screening technologies to identify compounds that selectively target specific cancer cells without harming healthy cells. These compounds are then tested in preclinical and clinical studies to demonstrate their efficacy and safety for use in humans. One of Verastem's main areas of focus is the development of drugs that target signaling pathways in cancer cells. The company has several drugs in its pipeline that aim to inhibit proteins that are central to the growth and survival of cancer cells. These include VS-6063, VS-5584, and VS-5095. VS-6063 is a small molecule that targets the inhibition of the Focal Adhesion Kinase (FAK) protein. FAK plays a key role in the development and progression of cancer by promoting the growth and movement of cancer cells. VS-6063 is currently being studied in clinical trials for the treatment of mesothelioma, pancreatic cancer, and other types of cancer. VS-5584 is a small molecule that targets the inhibition of the mammalian Target of Rapamycin (mTOR) protein. mTOR is an important regulator of cell growth and division that is overactive in many types of cancer. VS-5584 is currently being studied in clinical trials for the treatment of liver cancer and other types of cancer. VS-5095 is a small molecule that targets the inhibition of the Wnt protein, which plays a crucial role in regulating cell proliferation and differentiation. Wnt is also involved in the development of cancer as it can contribute to the transformation of normal cells into cancer cells. VS-5095 is currently in preclinical studies for the treatment of various types of cancer. Verastem also has a promising pipeline of RNA interference therapies that aim to inhibit the expression of specific genes in cancer cells. One such therapy currently in clinical testing, VS-6061, targets the inhibition of the KRAS gene, which is mutated in many types of cancer and can promote the survival and growth of cancer cells. Overall, Verastem aims to develop drugs that are better tailored to the individual needs of patients and help them fight their disease. With its innovative research approach and strong pipeline of drug candidates, the company has the potential to fundamentally change the way cancer is treated. Verastem ist eines der beliebtesten Unternehmen auf Eulerpool.com.