9,88 % | Artisan Partners Limited Partnership | 5 749 227 | -246 181 | 31.12.2023 |
8,20 % | Fidelity Management & Research Company LLC | 4 771 502 | -21 813 | 31.12.2023 |
6,92 % | Westfield Capital Management Company, L.P. | 4 030 634 | 228 457 | 31.12.2023 |
6,86 % | Janus Henderson Investors | 3 994 785 | 140 252 | 31.12.2023 |
6,85 % | T. Rowe Price Investment Management, Inc. | 3 989 830 | 5327 | 31.12.2023 |
6,45 % | Avoro Capital Advisors LLC | 3 755 555 | 85 555 | 31.12.2023 |
5,58 % | Wellington Management Company, LLP | 3 248 293 | -28 879 | 31.12.2023 |
3,75 % | Capital International Investors | 2 181 268 | 12 825 | 31.12.2023 |
2,61 % | MFS Investment Management | 1 518 356 | 254 634 | 31.12.2023 |
2,48 % | T. Rowe Price Associates, Inc. | 1 444 950 | -192 898 | 31.12.2023 |
17,36 % | RA Capital Management, LP | 10 107 400 | -612 155 | 31.12.2023 |
1,82 % | Franklin Advisers, Inc. | 1 058 937 | -148 698 | 31.12.2023 |
1,47 % | Invesco Advisers, Inc. | 856 203 | 237 928 | 31.12.2023 |
1,36 % | TimesSquare Capital Management, LLC | 792 945 | -49 856 | 31.12.2023 |
1,30 % | Sofinnova Investments, Inc | 754 032 | 0 | 31.12.2023 |
1,25 % | Putnam Investment Management, L.L.C. | 725 651 | -46 711 | 31.12.2023 |
1,07 % | Vestal Point Capital, LP | 625 000 | 625 000 | 31.12.2023 |
1,01 % | AllianceBernstein L.P. | 588 936 | -13 938 | 31.12.2023 |
0,93 % | Spyglass Capital Management LLC | 539 948 | -74 670 | 31.12.2023 |
0,91 % | Capital World Investors | 531 910 | 3296 | 31.03.2024 |
0,87 % | Brown Advisory | 505 947 | -4162 | 31.12.2023 |
0,73 % | Mikkelsen Jan Moller | 423 279 | 423 279 | 31.12.2023 |
0,73 % | Goldman Sachs & Company, Inc. | 422 854 | 12 881 | 31.12.2023 |
0,71 % | Medical Strategy GmbH | 414 506 | -6000 | 31.12.2023 |
0,62 % | SEI Investments Management Corporation | 361 830 | -34 610 | 31.12.2023 |
0,62 % | DWS Investment GmbH | 361 029 | 0 | 31.12.2023 |
0,60 % | Paradigm BioCapital Advisors LP | 351 700 | 351 700 | 31.12.2023 |
0,59 % | Fidelity Institutional Asset Management | 342 867 | -100 | 31.12.2023 |
0,53 % | American Century Investment Management, Inc. | 307 737 | -21 537 | 31.12.2023 |
0,52 % | BlackRock Institutional Trust Company, N.A. | 304 862 | 12 231 | 31.12.2023 |
0,51 % | Florida State Board of Administration | 294 243 | 128 050 | 30.09.2022 |
0,50 % | Rock Springs Capital Management LP | 290 000 | -135 500 | 31.12.2023 |
0,49 % | Q Global Advisors, LLC | 285 000 | 0 | 31.12.2023 |
0,49 % | ARS Investment Partners LLC | 282 744 | -3174 | 31.12.2023 |
0,46 % | D. E. Shaw & Co., L.P. | 265 157 | 44 604 | 31.12.2023 |
0,42 % | TD Asset Management Inc. | 244 578 | -22 782 | 31.12.2023 |
0,35 % | New York State Common Retirement Fund | 204 548 | -152 | 31.12.2023 |
0,35 % | Pictet Asset Management Ltd. | 203 654 | 32 784 | 31.12.2023 |
0,34 % | The Vanguard Group, Inc. | 199 499 | -233 494 | 31.12.2023 |
0,33 % | Fred Alger Management, LLC | 193 502 | -76 503 | 31.12.2023 |
0,32 % | Allspring Global Investments, LLC | 189 208 | -13 964 | 31.03.2024 |
0,31 % | Eventide Asset Management, LLC | 180 857 | -394 581 | 31.12.2023 |
0,29 % | Citadel Advisors LLC | 171 571 | 171 323 | 31.12.2023 |
0,29 % | Rice Hall James & Associates, LLC | 168 883 | -904 | 31.12.2023 |
0,28 % | Camber Capital Management LP | 165 000 | 165 000 | 31.12.2023 |
0,28 % | Finepoint Capital LP | 163 772 | 0 | 31.12.2023 |
0,28 % | Mellon Investments Corporation | 161 126 | -16 274 | 31.12.2023 |
0,26 % | First Turn Management, LLC | 151 587 | 151 587 | 31.12.2023 |
0,25 % | Adage Capital Management, L.P. | 144 000 | -382 371 | 31.12.2023 |
0,24 % | BofA Global Research (US) | 140 677 | -94 453 | 31.12.2023 |
0,24 % | abrdn Inc. | 138 791 | 138 791 | 31.12.2023 |
0,24 % | Tekla Capital Management LLC_NLE | 138 791 | 15 000 | 30.06.2023 |
0,23 % | Perceptive Advisors LLC | 132 176 | 132 176 | 31.12.2023 |
0,23 % | Saturn V Capital Management LLC | 131 759 | 19 286 | 31.12.2023 |
0,21 % | Schonfeld Strategic Advisors LLC | 124 901 | 86 001 | 31.12.2023 |
0,21 % | Dafna Capital Management, LLC | 123 472 | -12 740 | 31.12.2023 |
0,19 % | Thrivent Asset Management, LLC | 113 264 | -2190 | 31.12.2023 |
0,19 % | HSBC Global Asset Management (UK) Limited | 111 107 | 111 107 | 31.12.2023 |
0,17 % | Principal Global Investors (Equity) | 100 313 | 15 598 | 29.02.2024 |
0,17 % | Tri Locum Partners LP | 99 550 | 99 550 | 31.12.2023 |
0,17 % | Candriam Luxembourg S.A. | 99 375 | 0 | 29.02.2024 |
0,17 % | Candriam Belgium S.A. | 99 375 | -40 000 | 31.12.2023 |
0,15 % | BNP Paribas Asset Management USA, Inc. | 86 202 | 41 334 | 31.03.2024 |
0,14 % | Baillie Gifford & Co. | 81 670 | -4651 | 31.12.2023 |
0,14 % | Pictet Asset Management (Japan) Ltd. | 81 199 | 81 199 | 31.10.2023 |
0,13 % | Voloridge Investment Management, LLC | 73 335 | 53 427 | 31.12.2023 |
0,12 % | Tang Capital Management, LLC | 70 000 | 60 000 | 31.12.2023 |
0,12 % | Ensign Peak Advisors, Inc. | 67 544 | 0 | 31.12.2023 |
0,11 % | Morgan Stanley & Co. LLC | 66 470 | 44 517 | 31.12.2023 |
0,11 % | Columbia Threadneedle Investments (US) | 62 310 | 1734 | 31.12.2023 |
0,09 % | Geode Capital Management, L.L.C. | 55 090 | 535 | 31.12.2023 |
0,09 % | AEGON Investment Management B.V. | 54 156 | -2390 | 31.10.2023 |
0,09 % | Gray Foundation | 51 700 | 51 700 | 31.12.2023 |
0,08 % | Adar1 Capital Management LLC | 45 884 | 45 884 | 31.12.2023 |
0,08 % | JPMorgan Private Bank (United States) | 45 172 | -6802 | 31.12.2023 |
0,07 % | INVESCO Asset Management Limited | 43 320 | -2486 | 31.12.2023 |
0,07 % | Assenagon Asset Management S.A. | 38 120 | 2800 | 29.02.2024 |
0,06 % | Resolute Capital Asset Partners LLC | 36 400 | -1100 | 31.12.2023 |
0,06 % | Baillie Gifford Overseas Ltd. | 35 774 | 1418 | 29.02.2024 |
0,06 % | Matisse Capital | 34 635 | 8380 | 31.12.2023 |
0,06 % | Parametric Portfolio Associates LLC | 34 224 | 857 | 31.12.2023 |
0,05 % | Newton Investment Management North America, LLC | 31 627 | -1397 | 31.12.2023 |
0,05 % | Jane Street Capital, L.L.C. | 31 468 | 6751 | 31.12.2023 |
0,05 % | State Street Global Advisors (US) | 31 252 | 525 | 31.12.2023 |
0,05 % | BlackRock Advisors (UK) Limited | 30 939 | 1697 | 31.03.2024 |
0,05 % | Goldman Sachs Asset Management International | 30 423 | 0 | 31.01.2024 |
0,05 % | Deka Vermögensmanagement GmbH | 30 000 | 0 | 31.12.2023 |
0,05 % | BlackRock Asset Management Ireland Limited | 28 183 | 3454 | 31.12.2023 |
0,05 % | CAPTRUST Financial Advisors | 28 051 | 4022 | 31.12.2023 |
0,05 % | Jefferies LLC | 28 000 | 25 500 | 31.12.2023 |
0,05 % | UBS Financial Services, Inc. | 27 927 | -15 304 | 31.12.2023 |
0,05 % | Evoke Advisors | 27 069 | 27 069 | 31.12.2023 |
0,04 % | Altium Capital Management LP | 25 000 | 25 000 | 31.12.2023 |
0,04 % | Henry James International Management, Inc. | 24 495 | 0 | 31.12.2023 |
0,04 % | Wellington Management Japan Pte Ltd | 24 099 | 3863 | 30.06.2023 |
0,04 % | Manulife Investment Management (North America) Limited | 22 788 | -2785 | 31.12.2023 |
0,04 % | Millennium Management LLC | 22 391 | -20 461 | 31.12.2023 |
0,04 % | Morgan Stanley Smith Barney LLC | 20 450 | -180 | 31.12.2023 |
0,03 % | Affinity Asset Advisors LLC | 20 000 | -26 400 | 31.12.2023 |
0,03 % | Deka Investment GmbH | 20 000 | 4940 | 31.12.2022 |