9,26554 % | EcoR1 Capital, LLC | 10 655 366 | 10 655 366 | 22.01.2024 |
8,54617 % | F2 MG Ltd | 9 828 091 | 0 | 10.03.2023 |
5,73667 % | Invus Public Equities Advisors, LLC | 6 597 167 | 0 | 31.12.2023 |
4,95025 % | Fidelity Management & Research Company LLC | 5 692 782 | -3 989 678 | 31.12.2023 |
4,65728 % | Wilson (John Robert) | 5 355 877 | 0 | 31.12.2023 |
3,39479 % | Millennium Management LLC | 3 904 009 | 3 160 593 | 31.12.2023 |
2,82887 % | BlackRock Institutional Trust Company, N.A. | 3 253 206 | -173 002 | 31.12.2023 |
2,55531 % | The Vanguard Group, Inc. | 2 938 605 | 193 212 | 31.12.2023 |
2,52475 % | Hallal (David L) | 2 903 467 | 35 000 | 11.05.2023 |
2,18348 % | Woodline Partners LP | 2 511 004 | 444 338 | 31.12.2023 |
2,06515 % | Vera (Juan F. M.D.) | 2 374 928 | 35 000 | 11.05.2023 |
14,49980 % | ElevateBio LLC | 16 674 766 | 0 | 10.03.2023 |
14,46547 % | Gilead Sciences Inc | 16 635 286 | 0 | 31.12.2023 |
1,65910 % | Redmile Group, LLC | 1 907 969 | 0 | 31.12.2023 |
1,08977 % | Geode Capital Management, L.L.C. | 1 253 238 | 73 997 | 31.12.2023 |
1,00365 % | SunAmerica Asset Management, LLC | 1 154 193 | -101 | 31.12.2023 |
0,94009 % | State Street Global Advisors (US) | 1 081 104 | -10 894 | 31.12.2023 |
0,68738 % | Sinha (Vikas) | 790 492 | -885 | 2.04.2024 |
0,66258 % | Renaissance Technologies LLC | 761 965 | 428 243 | 31.12.2023 |
0,41377 % | Charles Schwab Investment Management, Inc. | 475 832 | 63 053 | 31.12.2023 |
0,34760 % | Northern Trust Investments, Inc. | 399 740 | -28 958 | 31.12.2023 |
0,34727 % | Two Sigma Investments, LP | 399 359 | 364 938 | 31.12.2023 |
0,34430 % | Goldman Sachs & Company, Inc. | 395 944 | 162 597 | 31.12.2023 |
0,32058 % | Miller Edward | 368 670 | -368 | 2.04.2024 |
0,28289 % | JPMorgan Asset Management U.K. Limited | 325 324 | 0 | 31.12.2023 |
0,28231 % | Marshall Wace LLP | 324 658 | 0 | 31.12.2023 |
0,26553 % | Morgan Stanley Smith Barney LLC | 305 359 | -67 037 | 31.12.2023 |
0,24795 % | Squarepoint Capital LLP | 285 138 | 222 701 | 31.12.2023 |
0,22581 % | Van (Beek Jeroen B) | 259 685 | -26 722 | 10.03.2023 |
0,21969 % | D. E. Shaw & Co., L.P. | 252 639 | 252 639 | 31.12.2023 |
0,20858 % | Citadel Advisors LLC | 239 869 | 239 869 | 31.12.2023 |
0,19907 % | Brenner (Malcolm) | 228 929 | 35 000 | 11.05.2023 |
0,18757 % | Pennant Investors, LP | 215 700 | 215 700 | 31.12.2023 |
0,18155 % | GSA Capital Partners LLP | 208 781 | 208 781 | 31.12.2023 |
0,17696 % | Commonwealth Financial Network | 203 500 | 203 500 | 31.12.2023 |
0,17373 % | Acadian Asset Management LLC | 199 785 | 199 785 | 31.12.2023 |
0,17132 % | Qube Research & Technologies Ltd | 197 018 | 197 018 | 31.12.2023 |
0,16572 % | 683 Capital Management LLC | 190 581 | 190 581 | 31.12.2023 |
0,14568 % | BNY Mellon Asset Management | 167 530 | 37 318 | 31.12.2023 |
0,12783 % | Piccina (Cintia) | 147 000 | 147 000 | 3.07.2023 |
0,12473 % | Morgan Stanley & Co. LLC | 143 434 | 57 054 | 31.12.2023 |
0,11878 % | BlackRock Investment Management, LLC | 136 597 | 3369 | 31.12.2023 |
0,11243 % | BlackRock Financial Management, Inc. | 129 299 | -23 596 | 31.12.2023 |
0,10817 % | AQR Capital Management, LLC | 124 400 | 124 400 | 31.12.2023 |
0,10783 % | Leen (Ann M) | 124 006 | 43 750 | 2.02.2023 |
0,07160 % | Samsara BioCapital, LLC | 82 336 | 0 | 31.12.2023 |
0,07152 % | Graham Capital Management, L.P. | 82 247 | 70 285 | 31.12.2023 |
0,06906 % | Lido Advisors, LLC | 79 416 | 0 | 31.12.2023 |
0,06597 % | Hagen (Brett R.) | 75 862 | -281 | 2.04.2024 |
0,06539 % | Bornstein (Jeffrey S) | 75 197 | 35 000 | 11.05.2023 |
0,06189 % | Dimensional Fund Advisors, L.P. | 71 169 | -42 765 | 31.12.2023 |
0,06101 % | BofA Global Research (US) | 70 162 | 26 561 | 31.12.2023 |
0,06098 % | Goldman Sachs Asset Management, L.P. | 70 127 | -3659 | 31.12.2023 |
0,06056 % | Barclays Bank PLC | 69 648 | 51 255 | 31.12.2023 |
0,05669 % | Jovan-Embiricos Morana | 65 197 | 35 000 | 11.05.2023 |
0,05603 % | AllianceBernstein L.P. | 64 430 | -6240 | 31.12.2023 |
0,05541 % | Jane Street Capital, L.L.C. | 63 727 | 15 351 | 31.12.2023 |
0,05532 % | Rhumbline Advisers Ltd. Partnership | 63 618 | -15 946 | 31.12.2023 |
0,05500 % | Parametric Portfolio Associates LLC | 63 245 | -30 451 | 31.12.2023 |
0,05457 % | Engineers Gate Manager, L.P. | 62 752 | 62 752 | 31.12.2023 |
0,05299 % | UBS Asset Management (Americas), Inc. | 60 936 | 0 | 31.03.2023 |
0,05272 % | UBS Financial Services, Inc. | 60 628 | 24 372 | 31.12.2023 |
0,04767 % | XTX Markets LLC | 54 815 | -29 234 | 31.12.2023 |
0,04315 % | Tudor Investment Corporation | 49 620 | 0 | 31.12.2023 |
0,03952 % | Amundi Asset Management, SAS | 45 448 | 0 | 31.12.2023 |
0,03747 % | T. Rowe Price International Ltd | 43 086 | 0 | 31.12.2023 |
0,03589 % | Virtu Americas LLC | 41 269 | 41 269 | 31.12.2023 |
0,03256 % | Mellon Investments Corporation | 37 444 | 0 | 31.12.2023 |
0,03122 % | Susquehanna International Group, LLP | 35 899 | -100 833 | 31.12.2023 |
0,03043 % | Adams (Derek N) | 35 000 | 35 000 | 11.05.2023 |
0,03043 % | Tomasello (Shawn Cline) | 35 000 | 35 000 | 11.05.2023 |
0,02918 % | JPMorgan Private Bank (United States) | 33 561 | -21 535 | 31.12.2023 |
0,02908 % | Raymond James Financial Services Advisors, Inc. | 33 440 | 33 440 | 31.12.2023 |
0,02795 % | Focus Financial Network, Inc. | 32 141 | 32 141 | 31.12.2023 |
0,02774 % | Dimensional Fund Advisors, Ltd. | 31 896 | 0 | 31.01.2024 |
0,02720 % | Victory Capital Management Inc. | 31 276 | 31 276 | 31.08.2022 |
0,02560 % | Northern Trust Global Investments | 29 438 | -4728 | 31.12.2023 |
0,02467 % | Atillasoy (Ercem) | 28 372 | -2095 | 21.10.2022 |
0,02331 % | Cubist Systematic Strategies, LLC | 26 803 | 13 286 | 31.12.2023 |
0,02174 % | Capstone Investment Advisors, LLC | 25 000 | 25 000 | 31.12.2023 |
0,02010 % | American Century Investment Management, Inc. | 23 111 | 22 281 | 31.12.2023 |
0,02001 % | Manulife Investment Management (North America) Limited | 23 010 | 23 010 | 31.12.2023 |
0,01995 % | Principal Global Investors (Equity) | 22 937 | -2531 | 31.12.2023 |
0,01983 % | Vaughan Nelson Investment Management, L.P. | 22 808 | 0 | 31.12.2023 |
0,01878 % | DWS Investments UK Limited | 21 594 | 0 | 31.12.2023 |
0,01870 % | Voya Investment Management LLC | 21 504 | 0 | 31.12.2023 |
0,01832 % | State Street Global Advisors Ireland Limited | 21 065 | -77 | 30.04.2023 |
0,01696 % | PFG Investments, LLC | 19 500 | 19 500 | 31.12.2023 |
0,01504 % | SG Americas Securities, L.L.C. | 17 301 | -5992 | 31.12.2023 |
0,01371 % | Wells Fargo Bank, N.A. | 15 768 | 3101 | 31.12.2023 |
0,01342 % | Brainard (Diana) | 15 435 | -1533 | 2.04.2024 |
0,01304 % | Osaic Holdings, Inc. | 15 000 | 0 | 31.12.2023 |
0,01258 % | Tower Research Capital LLC | 14 463 | 8074 | 31.12.2023 |
0,01187 % | T. Rowe Price Associates, Inc. | 13 651 | 10 764 | 29.02.2024 |
0,01150 % | Florida State Board of Administration | 13 226 | 13 226 | 31.12.2023 |
0,01014 % | Invesco Advisers, Inc. | 11 659 | 2306 | 31.12.2023 |
0,01005 % | Vanguard Personalized Indexing Management, LLC | 11 553 | 11 553 | 31.12.2023 |
0,00944 % | RBC Wealth Management, International | 10 860 | 2313 | 31.12.2023 |
0,00738 % | Quantbot Technologies, LP | 8484 | 8484 | 31.12.2023 |
0,00729 % | California State Teachers Retirement System | 8379 | -47 986 | 31.12.2023 |