9,02 % | The Vanguard Group, Inc. | 10 343 893 | 575 285 | |
7,88 % | BlackRock Institutional Trust Company, N.A. | 9 044 827 | 364 068 | |
6,43 % | Temasek Holdings Pte. Ltd. | 7 381 116 | 0 | |
3,03 % | Barclays Bank PLC | 3 481 643 | 1 109 363 | |
2,65 % | Kohlberg Kravis Roberts & Co. L.P. | 3 036 576 | 500 | |
2,48 % | Millennium Management LLC | 2 842 319 | 2 625 640 | |
2,39 % | Medical Strategy GmbH | 2 743 998 | 0 | |
2,16 % | Pictet Asset Management Ltd. | 2 481 848 | 602 392 | |
1,97 % | BlackRock Financial Management, Inc. | 2 261 980 | 84 679 | |
1,85 % | BofA Global Research (US) | 2 118 804 | 645 221 | |
1,81 % | Geode Capital Management, L.L.C. | 2 081 601 | 136 634 | |
1,80 % | State Street Global Advisors (US) | 2 064 326 | −6 726 601 | |
1,78 % | Morgan Stanley & Co. LLC | 2 044 357 | −1 067 721 | |
1,73 % | Citadel Advisors LLC | 1 987 897 | −671 820 | |
1,68 % | C WorldWide Asset Management Fondsmaeglerselskab A/S | 1 928 464 | 0 | |
1,47 % | Two Sigma Investments, LP | 1 684 452 | 1 644 990 | |
1,44 % | Jacobs Levy Equity Management, Inc. | 1 648 878 | 1 459 943 | |
1,07 % | Lanfear (Dennis M) | 1 228 343 | 0 | |
1,02 % | Disciplined Growth Investors, Inc. | 1 166 727 | −16 899 | |
0,95 % | Peregrine Capital Management, LLC | 1 089 961 | −288 606 | |
0,90 % | DWS Investments UK Limited | 1 028 727 | 990 063 | |
0,87 % | AlphaCentric Advisors LLC. | 1 000 000 | 87 500 | |
0,87 % | LifeSci Fund Management LLC | 1 000 000 | 87 500 | |
0,78 % | Pictet Asset Management (Japan) Ltd. | 893 567 | 477 508 | |
0,75 % | Northern Trust Investments, Inc. | 859 420 | 34 282 | |
0,72 % | CM Management, LLC | 824 000 | 276 000 | |
0,68 % | Susquehanna International Group, LLP | 776 282 | 140 116 | |
0,67 % | Charles Schwab Investment Management, Inc. | 767 697 | 44 325 | |
0,66 % | Nuveen LLC | 760 376 | −219 406 | |
0,60 % | Fifth Lane Capital, LP | 691 703 | 0 | |
0,57 % | Macquarie Investment Management | 649 999 | 151 400 | |
0,52 % | Acadian Asset Management LLC | 592 232 | 592 232 | |
0,51 % | Hudson Bay Capital Management LP | 585 000 | 175 000 | |
0,51 % | Qube Research & Technologies Ltd | 583 671 | 583 671 | |
0,50 % | Atlas Venture | 568 408 | 568 408 | |
0,48 % | Brandywine Global Investment Management, LLC | 555 945 | −110 300 | |
0,48 % | Jane Street Capital, L.L.C. | 553 896 | 315 258 | |
0,46 % | Knott Partners Management, LLC | 526 312 | −103 688 | |
0,44 % | Woodline Partners LP | 500 000 | 0 | |
0,37 % | Goldman Sachs Asset Management, L.P. | 423 940 | 40 741 | |
0,36 % | Goldman Sachs & Company, Inc. | 413 635 | −524 927 | |
0,34 % | Rubric Capital Management LP | 395 207 | 395 207 | |
0,34 % | Cubist Systematic Strategies, LLC | 387 240 | −193 732 | |
0,33 % | Citi Investment Research (US) | 373 807 | −423 490 | |
0,32 % | AQR Capital Management, LLC | 371 366 | 330 233 | |
0,32 % | J.P. Morgan Securities LLC | 369 171 | 368 662 | |
0,32 % | SEI Investments Management Corporation | 365 422 | −473 695 | |
0,30 % | Group One Trading, L.P. | 341 457 | 341 457 | |
0,30 % | Ikarian Capital LLC | 340 787 | −525 000 | |
0,27 % | Bridge City Capital, LLC | 315 384 | 2 450 | |
0,27 % | Lighthouse Partners | 313 134 | 313 134 | |
0,25 % | BlackRock Investment Management, LLC | 285 272 | 23 543 | |
0,24 % | BlackRock Investment Management (UK) Ltd. | 275 274 | −6 385 | |
0,23 % | BNY Mellon Asset Management | 265 279 | −26 176 | |
0,22 % | Credit Suisse Funds AG | 257 700 | −40 350 | |
0,22 % | XTX Markets LLC | 250 717 | 230 738 | |
0,20 % | HRT Financial LP | 235 077 | 235 077 | |
0,19 % | Tyche Wealth Partners LLC | 215 902 | 215 902 | |
0,18 % | Cambridge Investment Research Advisors, Inc. | 205 143 | 182 061 | |
0,17 % | Los Angeles Capital Management LLC | 196 210 | 59 390 | |
0,17 % | Schweizerische Nationalbank | 196 000 | −13 100 | |
0,17 % | Point72 Asset Management, L.P. | 190 823 | 183 332 | |
0,15 % | Pennant Investors, LP | 168 100 | 168 100 | |
0,14 % | BlackRock Asset Management Ireland Limited | 164 195 | 10 520 | |
0,14 % | Fidelity Management & Research Company LLC | 161 209 | 16 346 | |
0,14 % | Squarepoint Capital LLP | 161 125 | 161 125 | |
0,14 % | AllianceBernstein L.P. | 156 000 | 0 | |
0,13 % | Laurion Capital Management LP | 147 646 | 17 228 | |
0,13 % | UBS Financial Services, Inc. | 144 326 | −164 785 | |
0,11 % | D. E. Shaw & Co., L.P. | 127 610 | −578 798 | |
0,11 % | Rhumbline Advisers Ltd. Partnership | 124 678 | −2 998 | |
0,10 % | Marshall Wace LLP | 117 180 | −2 195 026 | |
0,10 % | Deka Investment GmbH | 116 600 | 0 | |
0,10 % | New York State Common Retirement Fund | 111 210 | −126 | |
0,10 % | Birchview Capital, LP | 110 000 | 110 000 | |
0,09 % | California State Teachers Retirement System | 105 021 | −1 064 | |
0,09 % | Boothbay Fund Management, LLC | 101 144 | −96 222 | |
0,09 % | Walleye Capital LLC | 100 055 | 58 102 | |
0,09 % | Deutsche Bank Securities Inc. | 100 000 | 100 000 | |
0,09 % | Wahlstrom (Mats) | 99 988 | 99 988 | |
0,09 % | HSBC Global Asset Management (UK) Limited | 99 864 | 16 535 | |
0,09 % | BlackRock Advisors (UK) Limited | 99 197 | −3 402 | |
0,09 % | Voya Investment Management LLC | 98 976 | 36 072 | |
0,09 % | MFS Investment Management | 98 318 | −3 104 | |
0,09 % | Legato Capital Management LLC | 98 229 | 0 | |
0,08 % | UBS Asset Management (Switzerland) | 96 611 | 0 | |
0,08 % | Northern Trust Global Investments | 89 938 | −15 291 | |
0,07 % | Legal & General Investment Management Ltd. | 83 637 | 0 | |
0,07 % | Jefferies LLC | 83 625 | 43 000 | |
0,07 % | Reider (Paul) | 81 277 | 0 | |
0,07 % | Assenagon Asset Management S.A. | 76 525 | 5 538 | |
0,07 % | Vexler (Vladimir) | 76 362 | 0 | |
0,07 % | Stilwell (McDavid H.) | 75 305 | −8 507 | |
0,07 % | DSS Wealth Management, Inc. | 74 805 | 14 805 | |
0,06 % | Brevan Howard Capital Management LP | 73 562 | 62 110 | |
0,06 % | SG Americas Securities, L.L.C. | 73 174 | 73 174 | |
0,06 % | Simplex Trading, LLC | 73 038 | 24 145 | |
0,06 % | Occudo Quantitative Strategies LP | 70 529 | 70 529 | |
0,06 % | Steel Peak Wealth Management LLC | 69 000 | 0 | |
0,06 % | Nomura Securities Co., Ltd. | 68 300 | 47 290 | |