9,76 % | Ridgeback Capital Management, L.P. | 1 485 898 | 197 637 | |
5,33 % | Gilde Healthcare Partners B.V. | 812 500 | 812 500 | |
4,60 % | 683 Capital Management LLC | 700 000 | −122 500 | |
2,91 % | New Enterprise Associates (NEA) | 442 649 | 0 | |
2,77 % | Point72 Asset Management, L.P. | 422 582 | 0 | |
2,10 % | Hoess (Adi Ph.D.) | 319 676 | 66 083 | |
1,34 % | Millennium Management LLC | 204 818 | −104 018 | |
1,10 % | Eversept Partners, LP | 167 668 | 0 | |
0,96 % | Fischer (Wolfgang) | 145 537 | 37 291 | |
0,93 % | Morgan Stanley & Co. LLC | 142 213 | 39 459 | |
0,93 % | The Vanguard Group, Inc. | 141 025 | 0 | |
0,92 % | Two Sigma Investments, LP | 140 535 | −17 087 | |
0,63 % | Verition Fund Management LLC | 96 597 | −12 203 | |
0,59 % | Mueller (Denise) | 89 876 | 35 709 | |
0,55 % | Schottelius (Arndt) | 83 542 | 35 709 | |
0,50 % | Harstrick (Andreas) | 76 042 | 35 709 | |
0,43 % | Smith (Angus W) | 65 708 | 13 291 | |
0,42 % | Kennedy Capital Management LLC | 63 224 | 63 224 | |
0,40 % | Marshall Wace LLP | 60 730 | 60 730 | |
0,38 % | Tekla Capital Management LLC_NLE | 58 604 | 0 | |
0,38 % | BNP Paribas Securities Corp. North America | 57 198 | 16 317 | |
0,36 % | Vestal Point Capital, LP | 54 607 | 54 607 | |
0,35 % | State Street Global Advisors (US) | 52 936 | 1 232 | |
0,27 % | Intellectus Partners, LLC | 41 039 | 1 120 | |
0,25 % | Hecht (Thomas M.D.) | 38 537 | 4 500 | |
0,24 % | Nan Fung Life Sciences | 37 247 | 0 | |
0,23 % | Alyeska Investment Group, L.P. | 35 000 | 0 | |
0,20 % | ACT Capital Management, L.L.C. | 30 880 | 0 | |
0,17 % | UBS O'Connor LLC | 25 494 | −56 506 | |
0,14 % | abrdn Inc. | 20 862 | 20 862 | |
0,14 % | Ehmer (Bernhard R M) | 20 833 | 3 000 | |
0,13 % | Commonwealth Financial Network | 20 476 | 14 856 | |
0,13 % | Telemetry Investments, L.L.C. | 20 000 | 650 | |
0,13 % | Grau (Ulrich Michael) | 20 000 | 3 000 | |
0,10 % | BlackRock Financial Management, Inc. | 15 332 | 0 | |
0,10 % | Welten (Harry) | 15 000 | 4 000 | |
0,10 % | Simon (Mathieu) | 15 000 | 4 000 | |
0,09 % | EWA, LLC | 14 253 | 14 253 | |
0,09 % | Jenkins (Annalisa M) | 14 000 | 2 000 | |
0,09 % | Wells Fargo Advisors | 13 951 | −2 210 | |
0,09 % | Geode Capital Management, L.L.C. | 13 595 | 0 | |
0,08 % | Fidelity Management & Research Company LLC | 12 647 | −125 328 | |
0,07 % | Kemmerich-Keil (Uta) | 11 000 | 5 000 | |
0,06 % | Acadian Asset Management LLC | 9 139 | −1 863 | |
0,06 % | Brown Advisory | 9 000 | 0 | |
0,05 % | Squarepoint Capital LLP | 8 028 | 6 186 | |
0,05 % | Barclays Bank PLC | 7 517 | 0 | |
0,05 % | State Street Global Advisors Ireland Limited | 7 494 | −27 | |
0,05 % | Citadel Advisors LLC | 7 176 | 2 016 | |
0,04 % | LPL Financial LLC | 6 225 | 2 100 | |
0,04 % | Harbor Investment Advisory, LLC | 5 870 | 0 | |
0,04 % | Jane Street Capital, L.L.C. | 5 681 | −7 300 | |
0,03 % | LMR Partners LLP | 5 136 | 0 | |
0,03 % | Osaic Holdings, Inc. | 4 191 | −970 | |
0,03 % | Cubist Systematic Strategies, LLC | 3 971 | −4 096 | |
0,02 % | RBC Dominion Securities, Inc. | 3 738 | −620 | |
0,02 % | BlackRock Institutional Trust Company, N.A. | 3 549 | −89 618 | |
0,02 % | Cetera Investment Advisers LLC | 3 000 | 1 500 | |
0,02 % | Susquehanna International Group, LLP | 2 932 | 1 062 | |
0,02 % | Goldman Sachs & Company, Inc. | 2 728 | −2 857 | |
0,02 % | U.S. Bancorp Asset Management, Inc. | 2 400 | 0 | |
0,01 % | XTX Markets LLC | 1 976 | 1 976 | |
0,01 % | Vident Investment Advisory, LLC | 1 733 | −5 | |
0,01 % | Clear Harbor Asset Management, LLC | 1 450 | 0 | |
0,01 % | BMO Capital Markets (US) | 1 365 | 400 | |
0,01 % | Dimensional Fund Advisors, L.P. | 1 332 | −9 659 | |
0,01 % | Tower Research Capital LLC | 1 128 | −2 980 | |
0,01 % | Hightower Advisors, LLC | 1 100 | 1 100 | |
0,01 % | Morgan Stanley Smith Barney LLC | 1 053 | −20 | |
0,01 % | MONTAG Wealth Management | 1 000 | 1 000 | |
0,01 % | Blackstone Alternative Investment Advisors LLC | 890 | 490 | |
0,00 % | Mackenzie Financial Corporation | 657 | −1 596 | |
0,00 % | PNC Investments LLC | 600 | 0 | |
0,00 % | Group One Trading, L.P. | 461 | −20 | |
0,00 % | Point72 Asia (Singapore) Pte. Ltd. | 421 | 421 | |
0,00 % | BlackRock Investment Management (UK) Ltd. | 314 | 0 | |
0,00 % | Qube Research & Technologies Ltd | 254 | −1 770 | |
0,00 % | BofA Global Research (US) | 180 | −271 | |
0,00 % | Newbridge Capital Management | 150 | 0 | |
0,00 % | Independent Financial Partners | 115 | 0 | |
0,00 % | Wetzel Investment Advisors Inc | 100 | 100 | |
0,00 % | Simplex Trading, LLC | 90 | −28 | |
0,00 % | RBC Capital Markets Wealth Management | 50 | 47 | |
0,00 % | City National Rochdale, LLC | 34 | 34 | |
0,00 % | Ronald Blue Trust, Inc. | 34 | 34 | |
0,00 % | J.P. Morgan Securities plc | 20 | −2 873 | |
0,00 % | Parkside Financial Bank & Trust | 15 | 15 | |
0,00 % | Citi Investment Research (US) | 12 | −201 | |
0,00 % | Cape Investment Advisory, Inc. | 10 | 0 | |
0,00 % | Northwestern Mutual Capital, LLC | 1 | 1 | |
0 % | VR Adviser, LLC | 0 | −142 857 | |
0 % | Ellevest, Inc. | 0 | −3 | |
0 % | MYDA Advisors LLC | 0 | −4 000 | |
0 % | Steward Partners Investment Advisory, LLC | 0 | −50 | |
0 % | MetLife Investment Management, LLC | 0 | −2 190 | |
0 % | Ergoteles Capital | 0 | −14 130 | |
0 % | Cresset Asset Management, LLC | 0 | −2 676 | |
0 % | Acuitas Investments LLC | 0 | −3 899 | |
0 % | Susquehanna Fundamental Investments, LLC | 0 | −4 072 | |
0 % | Altium Capital Management LP | 0 | −90 000 | |