9,70 % | Viking Global Investors LP | 2.456.292 | 0 | 31.12.2023 |
6,65 % | BVF Partners L.P. | 1.685.219 | 0 | 31.12.2023 |
6,07 % | Vivo Capital, LLC | 1.538.461 | 0 | 31.12.2023 |
6,07 % | Deerfield Management Company, L.P. | 1.538.461 | 0 | 31.12.2023 |
6,04 % | OrbiMed Advisors, LLC | 1.529.115 | 0 | 31.12.2023 |
5,63 % | Soleus Capital Management, L.P. | 1.425.634 | 78.265 | 31.12.2023 |
5,13 % | Adage Capital Management, L.P. | 1.300.000 | 0 | 31.12.2023 |
4,54 % | The Vanguard Group, Inc. | 1.150.253 | 0 | 31.12.2023 |
2,93 % | Tang Capital Management, LLC | 741.514 | -150.000 | 31.12.2023 |
2,27 % | Citadel Advisors LLC | 576.231 | -317.554 | 31.12.2023 |
1,19 % | BlackRock Institutional Trust Company, N.A. | 301.255 | 2.659 | 31.12.2023 |
0,92 % | Acuta Capital Partners, LLC | 232.249 | 2.249 | 31.12.2023 |
0,92 % | Geode Capital Management, L.L.C. | 232.128 | 12.213 | 31.12.2023 |
0,83 % | Opaleye Management Inc. | 211.400 | 0 | 31.12.2023 |
0,80 % | Sectoral Asset Management Inc. | 203.327 | 0 | 31.12.2023 |
0,80 % | Bank Vontobel AG | 203.327 | 0 | 31.12.2023 |
0,64 % | Susquehanna International Group, LLP | 162.312 | 140.042 | 31.12.2023 |
0,63 % | Jefferies LLC | 159.541 | 0 | 31.12.2023 |
0,59 % | LifeSci Fund Management LLC | 150.000 | 0 | 31.12.2023 |
0,59 % | AlphaCentric Advisors LLC. | 150.000 | 0 | 31.12.2023 |
0,56 % | Morgan Stanley & Co. LLC | 141.786 | 132.584 | 31.12.2023 |
0,33 % | State Street Global Advisors (US) | 83.587 | 23.700 | 31.12.2023 |
0,33 % | Millennium Management LLC | 83.114 | 83.114 | 31.12.2023 |
0,29 % | Citi Investment Research (US) | 73.908 | 43.833 | 31.12.2023 |
0,29 % | Stuglik (Brian M) | 73.227 | 2.142 | 26.3.2024 |
0,24 % | UBS O'Connor LLC | 61.803 | -94.101 | 31.12.2023 |
0,21 % | RBC Capital Markets Wealth Management | 54.066 | 12.085 | 31.12.2023 |
0,20 % | ExodusPoint Capital Management, LP | 51.379 | 51.379 | 31.12.2023 |
0,18 % | Northern Trust Investments, Inc. | 44.873 | 255 | 31.12.2023 |
0,17 % | Paterson (Daniel W) | 43.849 | 1.227 | 26.3.2024 |
0,16 % | Dimensional Fund Advisors, L.P. | 39.423 | 1.268 | 31.12.2023 |
0,12 % | Renaissance Technologies LLC | 31.365 | -15.000 | 31.12.2023 |
0,10 % | NewEdge Wealth, LLC | 25.885 | 0 | 31.12.2023 |
0,10 % | CornerCap Investment Counsel, Inc. | 25.274 | 0 | 31.12.2023 |
0,09 % | Two Sigma Investments, LP | 22.612 | -37.957 | 31.12.2023 |
0,09 % | Goldman Sachs & Company, Inc. | 21.799 | -15.278 | 31.12.2023 |
0,08 % | Gagnon (Robert E) | 20.918 | 714 | 26.3.2024 |
0,08 % | BofA Global Research (US) | 19.315 | -3.161 | 31.12.2023 |
0,07 % | Telemetry Investments, L.L.C. | 18.750 | 3.125 | 31.12.2022 |
0,07 % | Stifel, Nicolaus & Company, Incorporated | 17.445 | 4.984 | 31.12.2023 |
0,06 % | Abaris Investment Management AG | 15.000 | 6.667 | 30.6.2023 |
0,05 % | Aries Wealth Management, LLC | 13.081 | 0 | 31.12.2023 |
0,05 % | Avantis Investors | 12.345 | 6.972 | 31.3.2024 |
0,05 % | BNY Mellon Asset Management | 11.499 | -11.259 | 31.12.2023 |
0,05 % | BlackRock (Netherlands) B.V. | 11.403 | 11.403 | 31.12.2023 |
0,04 % | Cannon Global Investment Management, LLC | 11.100 | 11.100 | 31.3.2024 |
0,04 % | Jacobs Levy Equity Management, Inc. | 10.103 | 0 | 31.12.2023 |
0,03 % | Charles Schwab Investment Management, Inc. | 7.159 | 0 | 29.2.2024 |
0,02 % | Calkins (Daniel) | 6.125 | -6 | 5.4.2024 |
0,02 % | Dimensional Fund Advisors, Ltd. | 6.114 | 0 | 31.1.2024 |
0,02 % | BlackRock Advisors (UK) Limited | 6.023 | 6.023 | 31.12.2023 |
0,02 % | Wells Fargo Advisors | 5.252 | 700 | 31.12.2023 |
0,01 % | BlackRock Financial Management, Inc. | 3.699 | 0 | 31.12.2023 |
0,01 % | Advisory Services Network, LLC | 3.094 | 3.094 | 31.12.2023 |
0,01 % | Loring, Wolcott & Coolidge Fiduciary Advisors, LLP | 2.949 | 0 | 31.12.2023 |
0,01 % | UBS Financial Services, Inc. | 2.914 | 1.273 | 31.12.2023 |
0,01 % | BlackRock Investment Management (UK) Ltd. | 2.530 | 2.530 | 31.12.2023 |
0,01 % | Qube Research & Technologies Ltd | 2.367 | 2.367 | 31.12.2023 |
0,01 % | Welzia Management SGIIC S.A. | 2.222 | 2.222 | 31.12.2023 |
0,01 % | American Century Investment Management, Inc. | 1.884 | 0 | 31.3.2024 |
0,01 % | Morgan Stanley Smith Barney LLC | 1.814 | -123 | 31.12.2023 |
0,01 % | BlackRock Investment Management, LLC | 1.602 | 1.602 | 31.12.2023 |
0,01 % | Osaic Holdings, Inc. | 1.542 | -1.562 | 31.12.2023 |
0,01 % | Blackstone Alternative Investment Advisors LLC | 1.450 | -567 | 31.3.2023 |
0,01 % | Fidelity Management & Research Company LLC | 1.386 | 0 | 31.12.2023 |
0,01 % | Simplex Trading, LLC | 1.292 | 730 | 31.12.2023 |
0,01 % | IFAM Capital | 1.286 | 0 | 31.12.2023 |
0,00 % | Barclays Bank PLC | 1.061 | -3.701 | 31.12.2023 |
0,00 % | Rhumbline Advisers Ltd. Partnership | 674 | 0 | 31.12.2023 |
0,00 % | RBC Capital Partners | 551 | 32 | 31.12.2023 |
0,00 % | Kauffman (Michael G) | 550 | 0 | 26.3.2024 |
0,00 % | J.P. Morgan Securities plc | 341 | 0 | 31.12.2023 |
0,00 % | American Portfolios Advisors, Inc | 249 | 0 | 30.9.2022 |
0,00 % | Tower Research Capital LLC | 200 | -921 | 31.12.2023 |
0,00 % | Wells Fargo Bank, N.A. | 183 | 10 | 31.12.2023 |
0,00 % | Northwestern Mutual Capital, LLC | 166 | 166 | 31.12.2023 |
0,00 % | 1919 Investment Counsel, LLC | 125 | 125 | 31.12.2023 |
0,00 % | Group One Trading, L.P. | 92 | -21 | 31.12.2023 |
0,00 % | Guggenheim Investments | 85 | 0 | 30.11.2023 |
0,00 % | First Manhattan Co. LLC | 81 | 0 | 31.12.2023 |
0,00 % | L2 Asset Management, LLC | 59 | 0 | 29.2.2024 |
0,00 % | Northern Trust Global Investments | 51 | 0 | 31.12.2023 |
0,00 % | RBC Brewin Dolphin Ireland | 44 | 0 | 31.12.2023 |
0,00 % | PSI Advisors, L.L.C. | 27 | 0 | 31.12.2023 |
0,00 % | Concourse Financial Group Securities, Inc | 16 | 0 | 31.12.2023 |
0,00 % | Harbour Investments, Inc | 14 | 0 | 31.12.2023 |
0,00 % | Global Retirement Partners, LLC | 8 | 0 | 31.12.2023 |
0,00 % | TimeScale Financial, Inc. | 1 | 0 | 30.6.2023 |
0 % | Ellevest, Inc. | 0 | -29 | 30.9.2022 |
0 % | McAdam, LLC | 0 | -2.697 | 30.6.2023 |
0 % | Ergoteles Capital | 0 | -5.323 | 31.3.2023 |
0 % | LUNIS Vermögensmanagement AG | 0 | -5.833 | 31.10.2022 |
0 % | Romano Wealth management | 0 | -83 | 31.3.2023 |
0 % | Valeo Financial Advisors LLC | 0 | -1.958 | 30.6.2023 |
0 % | AdvisorNet Wealth Partners | 0 | -9 | 31.12.2022 |
0 % | Acuitas Investments LLC | 0 | -5.258 | 31.12.2022 |
0 % | Susquehanna Fundamental Investments, LLC | 0 | -15.775 | 30.9.2022 |
0 % | ACCI Capital Investments SGIIC, SA | 0 | -11.667 | 31.12.2022 |
0 % | AJ Wealth Strategies, LLC | 0 | -2.847 | 30.6.2023 |
0 % | Altium Capital Management LP | 0 | -250.000 | 31.12.2022 |