7,79 % | RA Capital Management, LP | 46.202.425 | 0 | 31.12.2023 |
6,41 % | BlackRock Institutional Trust Company, N.A. | 38.042.621 | 4.941.607 | 31.12.2023 |
4,99 % | Deep Track Capital LP | 29.583.449 | 3.883.449 | 31.12.2023 |
4,80 % | The Vanguard Group, Inc. | 28.475.212 | 1.914.328 | 31.12.2023 |
4,32 % | State Street Global Advisors (US) | 25.625.606 | 254.221 | 31.12.2023 |
4,07 % | Vivo Capital, LLC | 24.143.681 | 7.619.047 | 31.12.2023 |
3,94 % | TCG Crossover Management, LLC | 23.375.839 | 0 | 31.12.2023 |
3,84 % | New Enterprise Associates (NEA) | 22.776.409 | 0 | 31.12.2023 |
2,48 % | Millennium Management LLC | 14.730.986 | -1.342.120 | 31.12.2023 |
1,85 % | Geode Capital Management, L.L.C. | 10.943.649 | 930.747 | 31.12.2023 |
1,81 % | BioImpact Capital LLC | 10.715.620 | 3.139 | 31.12.2023 |
1,74 % | Morgan Stanley & Co. LLC | 10.302.068 | 9.157.822 | 31.12.2023 |
1,60 % | Wellington Management Company, LLP | 9.484.971 | -920.655 | 31.12.2023 |
1,49 % | Sofinnova Investments, Inc | 8.814.497 | 5.111.951 | 31.12.2023 |
1,19 % | Fidelity Management & Research Company LLC | 7.032.352 | -528.714 | 31.12.2023 |
1,15 % | DWS Investment S.A. | 6.826.599 | 6.826.599 | 31.12.2023 |
0,75 % | Northern Trust Investments, Inc. | 4.429.376 | 239.975 | 31.12.2023 |
0,75 % | Segall Bryant & Hamill, LLC | 4.419.820 | -570.679 | 31.12.2023 |
0,70 % | Invesco Capital Management LLC | 4.171.546 | -184.093 | 31.12.2023 |
0,65 % | Charles Schwab Investment Management, Inc. | 3.842.500 | 208.170 | 31.12.2023 |
0,56 % | Armistice Capital LLC | 3.296.000 | -328.000 | 31.12.2023 |
0,51 % | Boxer Capital, L.L.C. | 3.000.000 | 0 | 31.12.2023 |
0,50 % | Ally Bridge Group NY LLC | 2.971.639 | 750.000 | 31.12.2023 |
0,47 % | Goldman Sachs & Company, Inc. | 2.770.966 | -325.946 | 31.12.2023 |
0,35 % | Marshall Wace LLP | 2.078.497 | -3.782.148 | 31.12.2023 |
0,28 % | Rafferty Asset Management LLC | 1.669.087 | -233.179 | 31.12.2023 |
0,27 % | Medical Strategy GmbH | 1.618.263 | -216.663 | 31.12.2023 |
0,27 % | Barclays Bank PLC | 1.575.585 | 11.236 | 31.12.2023 |
0,25 % | Nuveen LLC | 1.473.442 | 7.728 | 31.12.2023 |
0,24 % | UBS Financial Services, Inc. | 1.441.603 | 790.423 | 31.12.2023 |
0,23 % | BNY Mellon Asset Management | 1.361.074 | 94.097 | 31.12.2023 |
0,22 % | BlackRock Financial Management, Inc. | 1.323.304 | 4.061 | 31.12.2023 |
0,22 % | MML Investors Services, LLC | 1.295.228 | 0 | 31.12.2023 |
0,22 % | Walleye Capital LLC | 1.275.514 | -950.552 | 31.12.2023 |
0,21 % | BlackRock Investment Management, LLC | 1.250.278 | 12.865 | 31.12.2023 |
0,21 % | Russell Investments Trust Company | 1.237.234 | 204.765 | 31.12.2023 |
0,20 % | JP Morgan Asset Management | 1.197.956 | -236.289 | 31.12.2023 |
0,19 % | Kennedy Capital Management LLC | 1.135.195 | 1.135.195 | 31.12.2023 |
0,17 % | BlackRock Advisors (UK) Limited | 989.520 | 34.941 | 31.3.2024 |
0,15 % | Nan Fung Life Sciences | 913.550 | 160.000 | 31.12.2023 |
0,14 % | BlackRock Asset Management Ireland Limited | 828.598 | 48.443 | 31.12.2023 |
0,13 % | Velan Capital Investment Management LP | 778.500 | 0 | 31.12.2023 |
0,13 % | Schweizerische Nationalbank | 773.600 | -232.900 | 31.12.2023 |
0,12 % | BNP Paribas Securities Corp. North America | 714.012 | 196.328 | 31.12.2023 |
0,12 % | Citi Investment Research (US) | 711.949 | -93.962 | 31.12.2023 |
0,12 % | Rhumbline Advisers Ltd. Partnership | 709.143 | 3.157 | 31.12.2023 |
0,12 % | Susquehanna International Group, LLP | 699.443 | 227.634 | 31.12.2023 |
0,12 % | Crestline Investors, Inc. | 687.378 | 102.227 | 31.12.2023 |
0,11 % | Credit Suisse Funds AG | 669.128 | 25.745 | 31.12.2023 |
0,11 % | Citadel Advisors LLC | 643.164 | 251.455 | 31.12.2023 |
0,10 % | Columbia Threadneedle Investments (US) | 617.363 | 13.262 | 31.12.2023 |
0,10 % | Jane Street Capital, L.L.C. | 613.415 | 425.063 | 31.12.2023 |
0,10 % | Exome Asset Management LLC | 607.500 | 607.500 | 31.12.2023 |
0,09 % | BofA Global Research (US) | 546.796 | -657.273 | 31.12.2023 |
0,09 % | AllianceBernstein L.P. | 512.741 | 0 | 31.12.2023 |
0,08 % | HealthCor Management, L.P. | 500.000 | -1.404.234 | 31.12.2022 |
0,08 % | OrbiMed Advisors, LLC | 485.000 | 485.000 | 31.12.2023 |
0,08 % | Qube Research & Technologies Ltd | 466.674 | 466.674 | 31.12.2023 |
0,08 % | Northern Trust Global Investments | 452.765 | -416.531 | 31.12.2023 |
0,07 % | HRT Financial LP | 437.027 | 437.027 | 31.12.2023 |
0,07 % | California State Teachers Retirement System | 433.890 | -80.667 | 31.12.2023 |
0,07 % | JPMorgan Private Bank (United States) | 432.570 | 335.767 | 31.12.2023 |
0,07 % | Legal & General Investment Management Ltd. | 410.422 | 318 | 31.12.2023 |
0,07 % | Mellon Investments Corporation | 410.071 | 63.795 | 31.12.2023 |
0,07 % | BlackRock Investment Management (UK) Ltd. | 406.060 | -52.603 | 31.12.2023 |
0,07 % | Squarepoint Capital LLP | 392.197 | 149.531 | 31.12.2023 |
0,07 % | Goldman Sachs Asset Management, L.P. | 387.820 | -14.349 | 31.12.2023 |
0,06 % | Fubon Asset Management Company Ltd. | 375.514 | -11.781 | 29.2.2024 |
0,06 % | Assenagon Asset Management S.A. | 373.810 | 27.030 | 29.2.2024 |
0,06 % | State of Wisconsin Investment Board | 372.643 | -18.600 | 31.12.2023 |
0,06 % | Summit Wealth Strategies | 361.961 | 3.503 | 31.12.2023 |
0,06 % | Alps Advisors, Inc. | 358.782 | -27.518 | 31.12.2023 |
0,06 % | Private Advisor Group LLC | 351.144 | 3.558 | 31.12.2023 |
0,06 % | Allspring Global Investments, LLC | 344.060 | -6.962 | 31.3.2024 |
0,05 % | Polen Capital Management, LLC | 325.880 | -172.685 | 29.2.2024 |
0,05 % | Ostrum Asset Management | 311.500 | 311.500 | 31.12.2023 |
0,05 % | ProFund Advisors LLC | 275.823 | -47.034 | 31.12.2023 |
0,04 % | MetLife Investment Management, LLC | 262.662 | 0 | 31.12.2023 |
0,04 % | Manulife Investment Management (North America) Limited | 260.827 | 1.301 | 31.12.2023 |
0,04 % | Two Sigma Investments, LP | 255.019 | 255.019 | 31.12.2023 |
0,04 % | SunAmerica Asset Management, LLC | 254.663 | 6.123 | 31.12.2023 |
0,04 % | XTX Markets LLC | 253.796 | 197.952 | 31.12.2023 |
0,04 % | Kentucky Teachers' Retirement System | 246.560 | 0 | 31.12.2023 |
0,04 % | HighVista Strategies LLC | 240.234 | 39.341 | 31.12.2023 |
0,04 % | Northern Trust Global Investments Limited | 235.594 | -64.739 | 31.12.2023 |
0,04 % | UBS Asset Management (Switzerland) | 231.106 | 0 | 31.12.2023 |
0,04 % | Commonwealth Financial Network | 230.264 | 11.967 | 31.12.2023 |
0,04 % | Osaic Holdings, Inc. | 227.206 | -71.969 | 31.12.2023 |
0,04 % | Cambridge Investment Research Advisors, Inc. | 225.373 | -36.122 | 31.12.2023 |
0,04 % | DWS Investments UK Limited | 222.922 | -5.892 | 31.12.2023 |
0,04 % | New York State Common Retirement Fund | 210.890 | 25.959 | 31.12.2023 |
0,03 % | Voya Investment Management LLC | 204.125 | 3.881 | 31.12.2023 |
0,03 % | Rosalind Advisors, Inc. | 200.000 | 200.000 | 31.12.2023 |
0,03 % | SG Americas Securities, L.L.C. | 192.445 | 173.370 | 31.12.2023 |
0,03 % | Invesco Advisers, Inc. | 188.784 | -13.367 | 31.12.2023 |
0,03 % | T. Rowe Price International Ltd | 187.779 | 16.501 | 31.12.2023 |
0,03 % | Jefferies LLC | 183.391 | -71.109 | 31.12.2023 |
0,03 % | Inspire Investing | 181.369 | 35.584 | 31.12.2023 |
0,03 % | Janus Henderson Investors | 181.018 | -292 | 31.12.2023 |
0,03 % | BlackRock Asset Management Canada Limited | 171.769 | 41.746 | 31.12.2023 |