6,89 % | Fred Alger Management, LLC | 3.327.132 | -932.323 | 31.12.2023 |
6,77 % | Adage Capital Management, L.P. | 3.266.645 | 0 | 31.12.2023 |
5,53 % | BlackRock Institutional Trust Company, N.A. | 2.671.316 | 504.121 | 31.12.2023 |
5,37 % | State Street Global Advisors (US) | 2.594.470 | 1.061.628 | 31.12.2023 |
5,31 % | VR Adviser, LLC | 2.563.952 | 590.699 | 31.12.2023 |
4,40 % | The Vanguard Group, Inc. | 2.126.124 | 163.823 | 31.12.2023 |
4,37 % | Lynx1 Capital Advisors LLC | 2.110.401 | 4.401 | 31.12.2023 |
4,16 % | Deerfield Management Company, L.P. | 2.007.729 | -332.389 | 31.12.2023 |
4,15 % | Perceptive Advisors LLC | 2.003.058 | 870.567 | 31.12.2023 |
4,14 % | Bain Capital Life Sciences Investors, LLC | 2.000.000 | 0 | 31.12.2023 |
3,98 % | Holocene Advisors, LP | 1.920.323 | 737.277 | 31.12.2023 |
3,94 % | Commodore Capital LP | 1.900.000 | -625.753 | 31.12.2023 |
3,80 % | T. Rowe Price Investment Management, Inc. | 1.832.854 | 1.832.854 | 31.12.2023 |
3,37 % | Jennison Associates LLC | 1.626.628 | 204.261 | 31.12.2023 |
2,85 % | Redmile Group, LLC | 1.374.189 | -400.063 | 31.12.2023 |
2,80 % | Nichtberger (Steven) | 1.349.483 | 0 | 31.12.2023 |
2,59 % | Polar Capital LLP | 1.250.000 | 1.250.000 | 31.12.2023 |
2,32 % | BlackRock Financial Management, Inc. | 1.121.700 | 947.483 | 31.12.2023 |
1,56 % | Geode Capital Management, L.L.C. | 753.176 | 61.304 | 31.12.2023 |
1,47 % | Invesco Capital Management LLC | 709.297 | -130.328 | 31.12.2023 |
1,39 % | Invesco Advisers, Inc. | 670.629 | 656.211 | 31.12.2023 |
1,12 % | Wellington Management Company, LLP | 539.876 | 293.306 | 31.12.2023 |
1,08 % | Integral Health Asset Management, LLC | 520.000 | 190.000 | 31.12.2023 |
1,06 % | T. Rowe Price Associates, Inc. | 511.979 | 502.722 | 31.12.2023 |
1,01 % | TCG Crossover Management, LLC | 486.795 | 0 | 31.12.2023 |
0,93 % | StemPoint Capital LP | 450.706 | 450.706 | 31.12.2023 |
0,89 % | Sofinnova Investments, Inc | 429.395 | 429.395 | 31.12.2023 |
0,87 % | BlackRock Investment Management (UK) Ltd. | 420.620 | 418.920 | 31.12.2023 |
0,84 % | Victory Capital Management Inc. | 403.927 | 337.277 | 31.12.2023 |
0,72 % | Blackstone Alternative Asset Management, L.P. | 347.494 | 347.494 | 31.12.2023 |
0,62 % | Alkeon Capital Management LLC | 299.955 | 299.955 | 31.12.2023 |
0,60 % | Northern Trust Investments, Inc. | 288.513 | 15.506 | 31.12.2023 |
0,59 % | Point72 Asset Management, L.P. | 284.666 | 284.666 | 31.12.2023 |
0,52 % | Schonfeld Strategic Advisors LLC | 251.615 | 251.615 | 31.12.2023 |
0,51 % | Morgan Stanley & Co. LLC | 245.787 | 169.460 | 31.12.2023 |
0,50 % | Woodline Partners LP | 241.453 | 107.269 | 31.12.2023 |
0,50 % | Nuveen LLC | 239.977 | 103.999 | 31.12.2023 |
0,49 % | Voloridge Investment Management, LLC | 236.400 | 225.638 | 31.12.2023 |
0,48 % | Cutter Capital Management, LP | 230.000 | 230.000 | 31.12.2023 |
0,45 % | Ikarian Capital LLC | 216.620 | 216.620 | 31.12.2023 |
0,43 % | Rafferty Asset Management LLC | 209.263 | 91.113 | 31.12.2023 |
0,42 % | Goldman Sachs & Company, Inc. | 204.632 | -65.053 | 31.12.2023 |
0,41 % | Candriam Luxembourg S.A. | 200.000 | 200.000 | 29.2.2024 |
0,36 % | First Turn Management, LLC | 175.359 | 175.359 | 31.12.2023 |
0,33 % | BofA Global Research (US) | 160.520 | 19.334 | 31.12.2023 |
0,31 % | Norges Bank Investment Management (NBIM) | 151.944 | 151.944 | 31.12.2023 |
0,31 % | Ghost Tree Capital, LLC | 150.000 | 150.000 | 31.12.2023 |
0,30 % | Simon (Mark) | 143.144 | 7.000 | 3.4.2023 |
0,29 % | UBS Financial Services, Inc. | 138.645 | 103.662 | 31.12.2023 |
0,27 % | Barclays Bank PLC | 129.072 | 64.486 | 31.12.2023 |
0,26 % | Morgan Stanley Smith Barney LLC | 124.620 | -20.194 | 31.12.2023 |
0,24 % | Ensign Peak Advisors, Inc. | 118.002 | 118.002 | 31.12.2023 |
0,23 % | BlackRock Investment Management, LLC | 109.505 | 28.934 | 31.12.2023 |
0,20 % | BNY Mellon Asset Management | 97.558 | 2.996 | 31.12.2023 |
0,20 % | Charles Schwab Investment Management, Inc. | 96.310 | 305 | 31.12.2023 |
0,19 % | TD Asset Management Inc. | 93.630 | 93.630 | 31.12.2023 |
0,19 % | AllianceBernstein L.P. | 93.332 | -72.071 | 31.12.2023 |
0,18 % | Jane Street Capital, L.L.C. | 88.409 | 88.409 | 31.12.2023 |
0,18 % | RBC Capital Markets Wealth Management | 86.816 | -13.115 | 31.12.2023 |
0,18 % | Citi Investment Research (US) | 86.546 | 36.851 | 31.12.2023 |
0,17 % | BlackRock Advisors (UK) Limited | 82.375 | 2.553 | 31.3.2024 |
0,17 % | Rokos Capital Management LLP | 80.335 | -93.515 | 31.12.2023 |
0,16 % | Weatherbie Capital, LLC | 77.153 | 52.745 | 29.2.2024 |
0,15 % | Two Sigma Investments, LP | 74.791 | 28.066 | 31.12.2023 |
0,14 % | BlackRock Asset Management Ireland Limited | 69.114 | 50.924 | 31.12.2023 |
0,14 % | Neuberger Berman, LLC | 68.329 | 68.329 | 29.2.2024 |
0,14 % | PGIM Securities Investment Trust Enterprise | 67.000 | -118.000 | 31.12.2023 |
0,12 % | Oppenheimer Asset Management Inc. | 60.045 | 60.045 | 31.12.2023 |
0,12 % | Boothbay Fund Management, LLC | 58.755 | 58.755 | 31.12.2023 |
0,11 % | Nicholas Investment Partners, L.P. | 54.586 | 41.408 | 31.12.2023 |
0,11 % | Manulife Investment Management (North America) Limited | 52.677 | 39.427 | 31.12.2023 |
0,11 % | Qube Research & Technologies Ltd | 52.199 | 52.199 | 31.12.2023 |
0,11 % | Schweizerische Nationalbank | 51.000 | -10.100 | 31.12.2023 |
0,10 % | Marda (Anup) | 50.000 | 50.000 | 18.10.2022 |
0,10 % | Nan Fung Life Sciences | 47.150 | 0 | 31.12.2023 |
0,10 % | Exome Asset Management LLC | 46.700 | 46.700 | 31.12.2023 |
0,10 % | Churchill Management Group | 46.606 | -2.750 | 31.3.2024 |
0,10 % | Bridgeway Capital Management, LLC | 46.021 | -4.600 | 31.12.2023 |
0,09 % | Rhumbline Advisers Ltd. Partnership | 44.147 | 1.545 | 31.12.2023 |
0,09 % | MFS Investment Management | 42.890 | -1.560 | 29.2.2024 |
0,08 % | Newton Investment Management North America, LLC | 39.900 | 0 | 31.12.2023 |
0,08 % | Caption Management, LLC | 38.300 | 38.300 | 31.12.2023 |
0,08 % | LPL Financial LLC | 37.638 | -223 | 31.12.2023 |
0,07 % | SEB Investment Management AB | 35.072 | -137 | 29.2.2024 |
0,07 % | Citadel Advisors LLC | 33.880 | 31.417 | 31.12.2023 |
0,07 % | ProFund Advisors LLC | 33.858 | 13.737 | 31.12.2023 |
0,07 % | Goldman Sachs Asset Management, L.P. | 33.505 | 3.138 | 31.12.2023 |
0,07 % | Credit Suisse Funds AG | 33.388 | 13.360 | 31.12.2023 |
0,07 % | Envestnet Asset Management, Inc. | 33.081 | -42.284 | 31.12.2023 |
0,06 % | Assenagon Asset Management S.A. | 29.346 | 2.127 | 29.2.2024 |
0,06 % | Cubist Systematic Strategies, LLC | 29.241 | 29.241 | 31.12.2023 |
0,06 % | California State Teachers Retirement System | 28.717 | -3.444 | 31.12.2023 |
0,06 % | Osaic Holdings, Inc. | 27.680 | -19.690 | 31.12.2023 |
0,05 % | Legal & General Investment Management Ltd. | 25.611 | -6.032 | 31.12.2023 |
0,05 % | Dimensional Fund Advisors, L.P. | 25.375 | -53.330 | 31.12.2023 |
0,05 % | New York State Common Retirement Fund | 25.191 | 14.828 | 31.12.2023 |
0,05 % | Mirae Asset Global Investments (USA) LLC | 23.689 | 6.891 | 31.12.2023 |
0,05 % | Squarepoint Capital LLP | 23.633 | 4.341 | 31.12.2023 |
0,05 % | State of Wisconsin Investment Board | 23.053 | -5.656 | 31.12.2023 |
0,05 % | JPMorgan Private Bank (United States) | 22.779 | 22.779 | 31.12.2023 |