14,76741 % | Fidelity Management & Research Company LLC | 16 456 803 | 234 247 | 30. 6. 2024 |
9,04245 % | The Vanguard Group, Inc. | 10 076 910 | 2 309 068 | 30. 6. 2024 |
4,24633 % | BlackRock Institutional Trust Company, N.A. | 4 732 114 | -2 002 505 | 30. 6. 2024 |
4,18715 % | State Street Global Advisors (US) | 4 666 157 | -456 271 | 30. 9. 2024 |
3,24486 % | Ligand Pharmaceuticals Inc | 3 616 077 | -2 449 003 | 29. 3. 2023 |
2,06831 % | Lian (Brian) | 2 304 927 | -50 000 | 20. 9. 2024 |
1,85011 % | JP Morgan Asset Management | 2 061 758 | 1 242 750 | 30. 6. 2024 |
1,66824 % | Geode Capital Management, L.L.C. | 1 859 082 | -467 697 | 30. 6. 2024 |
1,26051 % | Susquehanna International Group, LLP | 1 404 715 | 1 118 798 | 30. 6. 2024 |
1,23957 % | Pictet Asset Management Ltd. | 1 381 374 | 3 338 | 30. 6. 2024 |
1,21541 % | Viking Global Investors LP | 1 354 450 | 259 510 | 30. 6. 2024 |
1,11372 % | AllianceBernstein L.P. | 1 241 125 | -319 753 | 30. 6. 2024 |
0,99703 % | J O Hambro Capital Management Limited | 1 111 095 | 393 933 | 30. 9. 2024 |
0,99327 % | Braidwell LP | 1 106 905 | 393 805 | 30. 6. 2024 |
0,82792 % | BlackRock Financial Management, Inc. | 922 637 | -95 956 | 30. 6. 2024 |
0,74173 % | Medical Strategy GmbH | 826 588 | -62 776 | 30. 6. 2024 |
0,73793 % | Northern Trust Investments, Inc. | 822 345 | -37 375 | 30. 6. 2024 |
0,70594 % | Westfield Capital Management Company, L.P. | 786 695 | 124 564 | 30. 6. 2024 |
0,68677 % | Fidelity Investments Canada ULC | 765 333 | 7 309 | 30. 6. 2024 |
0,64879 % | Millennium Management LLC | 723 014 | 325 925 | 30. 6. 2024 |
0,64732 % | Perceptive Advisors LLC | 721 377 | -272 721 | 30. 6. 2024 |
0,64122 % | Hood River Capital Management LLC | 714 578 | 42 650 | 30. 6. 2024 |
0,62511 % | Invesco Advisers, Inc. | 696 620 | 2 354 | 30. 6. 2024 |
0,60254 % | Charles Schwab Investment Management, Inc. | 671 475 | -167 509 | 30. 6. 2024 |
0,55851 % | Voya Investment Management LLC | 622 405 | -446 192 | 30. 6. 2024 |
0,52459 % | ClearBridge Investments, LLC | 584 601 | -12 588 | 30. 6. 2024 |
0,52367 % | Emerald Advisers LLC | 583 573 | 14 159 | 30. 9. 2024 |
0,50905 % | Fred Alger Management, LLC | 567 284 | 100 068 | 30. 6. 2024 |
0,50598 % | Macquarie Investment Management | 563 861 | 86 926 | 30. 6. 2024 |
0,50047 % | Goldman Sachs & Company, Inc. | 557 719 | 198 668 | 30. 6. 2024 |
0,47156 % | D. E. Shaw & Co., L.P. | 525 502 | 449 760 | 30. 6. 2024 |
0,45120 % | Baron Capital Management, Inc. | 502 819 | 9 560 | 30. 6. 2024 |
0,44324 % | Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 493 950 | -26 125 | 30. 9. 2024 |
0,43270 % | Morgan Stanley Smith Barney LLC | 482 202 | 145 718 | 30. 6. 2024 |
0,42685 % | Goldman Sachs Asset Management, L.P. | 475 686 | 197 963 | 30. 6. 2024 |
0,41859 % | Citadel Advisors LLC | 466 478 | -435 271 | 30. 6. 2024 |
0,40991 % | Principal Global Investors (Equity) | 456 799 | 95 960 | 30. 6. 2024 |
0,40648 % | Artia Global Partners LP | 452 979 | 19 399 | 30. 6. 2024 |
0,40561 % | Ensign Peak Advisors, Inc. | 452 011 | 165 851 | 30. 6. 2024 |
0,40398 % | Frontier Capital Management Company, LLC | 450 197 | 284 788 | 30. 6. 2024 |
0,39626 % | Raymond James & Associates, Inc. | 441 590 | 133 144 | 30. 9. 2024 |
0,37008 % | BofA Global Research (US) | 412 413 | 51 119 | 30. 6. 2024 |
0,35587 % | HRT Financial LP | 396 583 | 396 583 | 30. 6. 2024 |
0,34398 % | Jane Street Capital, L.L.C. | 383 332 | 36 244 | 30. 6. 2024 |
0,33982 % | Granahan Investment Management, LLC | 378 698 | 59 805 | 30. 6. 2024 |
0,33848 % | Mancini (Marianna) | 377 207 | 13 641 | 30. 7. 2024 |
0,30510 % | 683 Capital Management LLC | 340 000 | -15 000 | 30. 6. 2024 |
0,30112 % | Rafferty Asset Management LLC | 335 566 | 207 810 | 30. 6. 2024 |
0,28857 % | Morgan Stanley & Co. LLC | 321 584 | -102 619 | 30. 6. 2024 |
0,28628 % | Russell Investments Trust Company | 319 035 | -15 646 | 30. 6. 2024 |
0,28389 % | UBS Financial Services, Inc. | 316 362 | 43 587 | 30. 6. 2024 |
0,27188 % | Putnam Investment Management, L.L.C. | 302 981 | -21 311 | 30. 6. 2024 |
0,26084 % | UBS Asset Management (Americas), Inc. | 290 683 | 45 683 | 30. 6. 2024 |
0,24538 % | American Century Investment Management, Inc. | 273 449 | -558 683 | 30. 6. 2024 |
0,23046 % | BNP Paribas Securities Corp. North America | 256 824 | 178 410 | 30. 6. 2024 |
0,22718 % | Wasatch Global Investors Inc | 253 169 | -2 367 | 30. 6. 2024 |
0,22700 % | Eventide Asset Management, LLC | 252 969 | 0 | 30. 6. 2024 |
0,22434 % | Integral Health Asset Management, LLC | 250 000 | -200 000 | 30. 6. 2024 |
0,21317 % | 5AM Ventures | 237 560 | 0 | 30. 6. 2024 |
0,21231 % | MFS Investment Management | 236 601 | -56 984 | 30. 6. 2024 |
0,18063 % | Group One Trading, L.P. | 201 294 | 127 049 | 30. 6. 2024 |
0,17373 % | Schweizerische Nationalbank | 193 600 | 25 000 | 30. 6. 2024 |
0,17363 % | Nuveen LLC | 193 490 | -224 370 | 30. 6. 2024 |
0,16970 % | Dafna Capital Management, LLC | 189 117 | -5 000 | 30. 6. 2024 |
0,16635 % | Balyasny Asset Management LP | 185 382 | 76 787 | 30. 6. 2024 |
0,16365 % | Norges Bank Investment Management (NBIM) | 182 369 | 182 369 | 30. 6. 2024 |
0,16207 % | Mellon Investments Corporation | 180 610 | 101 327 | 30. 6. 2024 |
0,16152 % | Handelsbanken Kapitalf¿rvaltning AB | 180 000 | 158 100 | 30. 9. 2024 |
0,15947 % | Nepsis, Inc. | 177 714 | 177 714 | 30. 9. 2024 |
0,15683 % | Boone Capital Management LLC | 174 766 | -135 696 | 30. 6. 2024 |
0,14841 % | Columbia Threadneedle Investments (US) | 165 390 | -115 696 | 30. 6. 2024 |
0,14304 % | Renaissance Technologies LLC | 159 400 | 159 400 | 30. 6. 2024 |
0,14279 % | BNY Mellon Asset Management | 159 130 | -79 551 | 30. 6. 2024 |
0,13403 % | Zante (Gregory S) | 149 366 | -37 686 | 28. 10. 2024 |
0,13182 % | Discovery Capital Management, LLC | 146 900 | 146 900 | 30. 6. 2024 |
0,12764 % | Comerica, Inc. | 142 238 | 50 695 | 30. 6. 2024 |
0,12726 % | Squarepoint Capital LLP | 141 820 | 141 820 | 30. 6. 2024 |
0,12496 % | Harbor Capital Advisors, Inc. | 139 252 | 75 820 | 30. 9. 2024 |
0,12427 % | Eversept Partners, LP | 138 489 | 115 671 | 30. 6. 2024 |
0,12407 % | Ikarian Capital LLC | 138 262 | 138 262 | 30. 6. 2024 |
0,11773 % | BlackRock Investment Management (UK) Ltd. | 131 197 | 33 845 | 30. 6. 2024 |
0,11717 % | Parametric Portfolio Associates LLC | 130 576 | -64 222 | 30. 6. 2024 |
0,11693 % | Raymond James Financial Services Advisors, Inc. | 130 306 | 33 401 | 30. 9. 2024 |
0,11659 % | Steward Partners Investment Advisory, LLC | 129 923 | 45 650 | 30. 6. 2024 |
0,11419 % | Rhumbline Advisers Ltd. Partnership | 127 258 | -16 845 | 30. 6. 2024 |
0,11012 % | Polen Capital Management, LLC | 122 721 | 0 | 31. 8. 2024 |
0,10983 % | New York State Common Retirement Fund | 122 398 | 63 335 | 30. 9. 2024 |
0,10948 % | Altium Capital Management LP | 122 000 | 37 000 | 30. 6. 2024 |
0,10768 % | Tang Capital Management, LLC | 120 000 | 20 000 | 30. 6. 2024 |
0,10675 % | MPM BioImpact LLC | 118 960 | -31 040 | 30. 6. 2024 |
0,10319 % | Prosight Capital | 115 000 | 75 954 | 30. 6. 2024 |
0,10319 % | Rhenman & Partners Asset Management AB | 115 000 | -30 000 | 30. 6. 2024 |
0,10315 % | Melqart Asset Management (UK) Limited | 114 947 | 114 947 | 30. 6. 2024 |
0,09983 % | Foehr (Matthew W) | 111 250 | 0 | 15. 3. 2024 |
0,09927 % | Legal & General Investment Management Ltd. | 110 630 | 14 343 | 30. 6. 2024 |
0,09445 % | RBC Capital Markets Wealth Management | 105 252 | 31 968 | 30. 6. 2024 |
0,09435 % | Goldman Sachs Asset Management International | 105 140 | 0 | 30. 9. 2024 |
0,09387 % | Columbia Wanger Asset Management, LLC | 104 613 | 0 | 30. 6. 2024 |
0,09139 % | Wells Fargo Advisors | 101 850 | 72 391 | 30. 6. 2024 |
0,09082 % | William Blair & Company, L.L.C. (Research) | 101 207 | -198 028 | 30. 6. 2024 |