9,82400 % | Suvretta Capital Management, LLC | 7 167 591 | 0 | 31. 12. 2023 |
8,57257 % | Equal Talent Investments, Ltd. | 6 254 545 | 0 | 15. 8. 2023 |
6,88796 % | Avidity Partners Management LP | 5 025 454 | -985 646 | 31. 12. 2023 |
5,97550 % | BlackRock Institutional Trust Company, N.A. | 4 359 722 | -101 921 | 31. 12. 2023 |
4,61257 % | Prosight Capital | 3 365 333 | -1 405 466 | 31. 12. 2023 |
4,19885 % | The Vanguard Group, Inc. | 3 063 484 | 22 917 | 31. 12. 2023 |
4,01256 % | Millennium Management LLC | 2 927 563 | -474 550 | 31. 12. 2023 |
3,47937 % | Two Sigma Investments, LP | 2 538 547 | 1 190 209 | 31. 12. 2023 |
2,81206 % | Sphera Funds Management Ltd. | 2 051 676 | 0 | 31. 12. 2023 |
2,66995 % | Morningside Venture Investments, Ltd. | 1 947 993 | -3 500 000 | 15. 8. 2023 |
2,64117 % | OrbiMed Advisors, LLC | 1 927 000 | -3 536 000 | 31. 12. 2023 |
2,61263 % | Granahan Investment Management, LLC | 1 906 175 | 453 617 | 31. 12. 2023 |
1,85670 % | Geode Capital Management, L.L.C. | 1 354 648 | 62 031 | 31. 12. 2023 |
1,77072 % | Renaissance Technologies LLC | 1 291 919 | 683 223 | 31. 12. 2023 |
1,72236 % | Acadian Asset Management LLC | 1 256 635 | 424 942 | 31. 12. 2023 |
1,52968 % | State Street Global Advisors (US) | 1 116 052 | 3 492 | 31. 12. 2023 |
1,33064 % | Jacobs Levy Equity Management, Inc. | 970 835 | 662 259 | 31. 12. 2023 |
1,22079 % | Berger (Franklin Milan) | 890 691 | 0 | 1. 4. 2023 |
1,16967 % | Ikarian Capital LLC | 853 391 | 0 | 31. 12. 2023 |
1,13584 % | Qiming U.S. Ventures Management, LLC | 828 711 | 0 | 31. 12. 2023 |
0,96467 % | International Biotechnology Trust PLC | 703 825 | 703 825 | 30. 9. 2023 |
0,83779 % | Anson Funds Management LP. | 611 249 | 611 249 | 31. 12. 2023 |
0,81818 % | Victory Capital Management Inc. | 596 942 | 130 780 | 31. 12. 2023 |
0,67299 % | Northern Trust Investments, Inc. | 491 011 | -26 134 | 31. 12. 2023 |
0,59775 % | Fowler (John Franklin) | 436 115 | 0 | 1. 4. 2023 |
0,59121 % | Kirk (Christopher J) | 431 348 | 48 950 | 20. 7. 2023 |
0,57386 % | Goldman Sachs & Company, Inc. | 418 689 | -940 578 | 31. 12. 2023 |
0,51669 % | D. E. Shaw & Co., L.P. | 376 976 | 333 301 | 31. 12. 2023 |
0,50073 % | Citadel Advisors LLC | 365 329 | 203 077 | 31. 12. 2023 |
0,48025 % | Schroder Investment Management Ltd. (SIM) | 350 394 | 350 394 | 31. 12. 2023 |
0,42978 % | Nuveen LLC | 313 565 | 0 | 31. 12. 2023 |
0,42032 % | Tang Capital Management, LLC | 306 665 | 306 665 | 31. 12. 2023 |
0,38276 % | DWS Investment S.A. | 279 265 | 279 265 | 31. 12. 2023 |
0,35692 % | GSA Capital Partners LLP | 260 407 | 260 407 | 31. 12. 2023 |
0,33601 % | BlackRock Financial Management, Inc. | 245 150 | 0 | 31. 12. 2023 |
0,32678 % | Morgan Stanley & Co. LLC | 238 421 | 172 115 | 31. 12. 2023 |
0,31043 % | Charles Schwab Investment Management, Inc. | 226 490 | -118 950 | 31. 12. 2023 |
0,28101 % | BlackRock Investment Management, LLC | 205 027 | -5 208 | 31. 12. 2023 |
0,27671 % | BNP Paribas Securities Corp. North America | 201 887 | 118 088 | 31. 12. 2023 |
0,25590 % | Squarepoint Capital LLP | 186 705 | 33 780 | 31. 12. 2023 |
0,22959 % | BNY Mellon Asset Management | 167 512 | -41 621 | 31. 12. 2023 |
0,21738 % | Bridgeway Capital Management, LLC | 158 600 | -151 500 | 31. 12. 2023 |
0,18487 % | Boothbay Fund Management, LLC | 134 884 | 0 | 31. 12. 2023 |
0,14646 % | Rhumbline Advisers Ltd. Partnership | 106 855 | 0 | 31. 12. 2023 |
0,14225 % | HRT Financial LP | 103 785 | 103 785 | 31. 12. 2023 |
0,13437 % | Barclays Bank PLC | 98 037 | 85 445 | 31. 12. 2023 |
0,12231 % | BofA Global Research (US) | 89 241 | 24 823 | 31. 12. 2023 |
0,11706 % | Susquehanna International Group, LLP | 85 407 | 29 583 | 31. 12. 2023 |
0,11525 % | PanAgora Asset Management Inc. | 84 087 | 84 087 | 31. 12. 2023 |
0,11272 % | Amundi Asset Management, SAS | 82 243 | 82 243 | 31. 12. 2023 |
0,10836 % | AllianceBernstein L.P. | 79 058 | -8 600 | 31. 12. 2023 |
0,10137 % | Wells Fargo Advisors | 73 962 | -25 000 | 31. 12. 2023 |
0,09516 % | Jane Street Capital, L.L.C. | 69 432 | 69 432 | 31. 12. 2023 |
0,09437 % | Pale Fire Capital SE | 68 851 | 0 | 31. 12. 2023 |
0,08729 % | Kauffman (Michael G) | 63 690 | 0 | 1. 4. 2023 |
0,07789 % | Engineers Gate Manager, L.P. | 56 826 | 43 319 | 31. 12. 2023 |
0,07498 % | Mellon Investments Corporation | 54 705 | 0 | 31. 12. 2023 |
0,07190 % | Northern Trust Global Investments | 52 455 | -189 | 31. 12. 2023 |
0,06740 % | UBS Financial Services, Inc. | 49 174 | 15 021 | 31. 12. 2023 |
0,06352 % | T. Rowe Price International Ltd | 46 347 | 0 | 31. 12. 2023 |
0,06340 % | JPMorgan Private Bank (United States) | 46 259 | -26 818 | 31. 12. 2023 |
0,06033 % | XTX Markets LLC | 44 019 | -27 658 | 31. 12. 2023 |
0,06024 % | SG Americas Securities, L.L.C. | 43 950 | 11 109 | 31. 12. 2023 |
0,05441 % | Schiller (Mark C) | 39 695 | 39 695 | 15. 1. 2024 |
0,04862 % | SunAmerica Asset Management, LLC | 35 473 | -143 | 31. 12. 2023 |
0,04700 % | Occudo Quantitative Strategies LP | 34 294 | 0 | 31. 12. 2023 |
0,04078 % | Vaughan Nelson Investment Management, L.P. | 29 756 | 0 | 31. 12. 2023 |
0,03715 % | Principal Global Investors (Equity) | 27 107 | -1 905 | 31. 12. 2023 |
0,03447 % | Ironwood Investment Management, LLC | 25 148 | -3 462 | 31. 12. 2023 |
0,03294 % | Goldman Sachs Asset Management, L.P. | 24 032 | -1 707 | 31. 12. 2023 |
0,03255 % | New York State Common Retirement Fund | 23 748 | -146 | 31. 12. 2023 |
0,03196 % | Wexford Capital LP | 23 320 | 23 320 | 31. 12. 2023 |
0,02995 % | Wells Fargo Bank, N.A. | 21 853 | 4 332 | 31. 12. 2023 |
0,02799 % | Federated MDTA LLC | 20 420 | -7 188 | 31. 12. 2023 |
0,02741 % | Deka Investment GmbH | 20 000 | 20 000 | 31. 12. 2022 |
0,02733 % | Invesco Advisers, Inc. | 19 941 | 6 622 | 31. 12. 2023 |
0,02601 % | PGIM Quantitative Solutions LLC | 18 980 | -17 550 | 31. 12. 2023 |
0,02540 % | Florida State Board of Administration | 18 534 | 18 534 | 31. 12. 2023 |
0,02538 % | Fidelity Management & Research Company LLC | 18 514 | 11 205 | 31. 12. 2023 |
0,02439 % | Manulife Investment Management (North America) Limited | 17 798 | -994 | 31. 12. 2023 |
0,02211 % | Diversified Trust Company | 16 132 | 0 | 31. 3. 2024 |
0,02087 % | RBC Wealth Management, International | 15 224 | 3 242 | 31. 12. 2023 |
0,02056 % | Retirement Capital Strategies, Inc | 15 000 | 0 | 31. 12. 2023 |
0,01727 % | Blackstone Alternative Investment Advisors LLC | 12 600 | 1 700 | 31. 3. 2023 |
0,01635 % | Henig (Noreen) | 11 929 | 2 929 | 1. 4. 2023 |
0,01619 % | ProShare Advisors LLC | 11 812 | -2 211 | 31. 12. 2023 |
0,01610 % | California State Teachers Retirement System | 11 747 | -4 000 | 31. 12. 2023 |
0,01609 % | First Bank & Trust | 11 739 | 11 739 | 31. 3. 2024 |
0,01573 % | Tower Research Capital LLC | 11 480 | 1 008 | 31. 12. 2023 |
0,01508 % | Morgan Stanley Smith Barney LLC | 11 000 | 2 000 | 31. 12. 2023 |
0,01476 % | Citi Investment Research (US) | 10 769 | 9 798 | 31. 12. 2023 |
0,01361 % | Horizon Kinetics LLC | 9 932 | 0 | 29. 2. 2024 |
0,01144 % | Parametric Portfolio Associates LLC | 8 345 | -50 409 | 31. 12. 2023 |
0,00987 % | RBC Capital Partners | 7 198 | 7 198 | 31. 12. 2023 |
0,00934 % | Legal & General Investment Management Ltd. | 6 814 | 0 | 31. 12. 2023 |
0,00893 % | Amalgamated Bank Institutional Asset Management & Custody | 6 516 | -485 | 31. 12. 2023 |
0,00725 % | Mackenzie Financial Corporation | 5 287 | -1 924 | 31. 12. 2023 |
0,00718 % | T. Rowe Price Associates, Inc. | 5 236 | 0 | 29. 2. 2024 |
0,00603 % | BlackRock Investment Management (UK) Ltd. | 4 402 | 0 | 31. 12. 2023 |
0,00566 % | Ameritas Investment Partners, Inc. | 4 127 | 0 | 31. 12. 2023 |