16,81894 % | Cormorant Asset Management, LP | 2 025 000 | 0 | 30. 6. 2024 |
9,26080 % | Octagon Capital Advisors LP | 1 115 000 | 627 000 | 30. 9. 2024 |
5,86161 % | BlackRock Institutional Trust Company, N.A. | 705 738 | 489 032 | 30. 6. 2024 |
4,85871 % | The Vanguard Group, Inc. | 584 989 | 147 725 | 30. 6. 2024 |
3,67386 % | State Street Global Advisors (US) | 442 333 | 406 354 | 30. 6. 2024 |
3,57294 % | RA Capital Management, LP | 430 182 | 430 182 | 2. 2. 2024 |
3,54003 % | Tang Capital Management, LLC | 426 220 | 426 220 | 26. 1. 2024 |
3,32226 % | Adage Capital Management, L.P. | 400 000 | -15 000 | 30. 6. 2024 |
3,31942 % | Paradigm BioCapital Advisors LP | 399 658 | 399 658 | 26. 1. 2024 |
2,76380 % | Citadel Advisors LLC | 332 761 | -36 406 | 30. 6. 2024 |
2,70050 % | Darwin Global Management Ltd | 325 140 | 325 140 | 30. 6. 2024 |
2,57093 % | Ikarian Capital LLC | 309 540 | -249 731 | 30. 6. 2024 |
2,45241 % | T. Rowe Price Associates, Inc. | 295 270 | 102 775 | 30. 6. 2024 |
2,13882 % | Morgan Stanley & Co. LLC | 257 514 | 85 849 | 30. 6. 2024 |
2,07026 % | Woodline Partners LP | 249 259 | 208 278 | 30. 6. 2024 |
1,91908 % | Geode Capital Management, L.L.C. | 231 057 | 122 249 | 30. 6. 2024 |
1,87014 % | Sio Capital Management, LLC | 225 165 | 225 165 | 30. 6. 2024 |
1,83708 % | Assenagon Asset Management S.A. | 221 184 | -17 575 | 30. 9. 2024 |
1,79830 % | Point72 Asset Management, L.P. | 216 515 | -485 082 | 30. 6. 2024 |
1,79070 % | Avidity Partners Management LP | 215 600 | 215 600 | 30. 6. 2024 |
1,68831 % | Janus Henderson Investors | 203 272 | -135 802 | 30. 6. 2024 |
1,54273 % | K2 HealthVentures LLC | 185 745 | 185 745 | 31. 12. 2023 |
1,45349 % | Ghost Tree Capital, LLC | 175 000 | 118 059 | 30. 6. 2024 |
1,43266 % | SilverArc Capital Management, LLC | 172 492 | 140 512 | 30. 6. 2024 |
1,38533 % | Vivo Capital, LLC | 166 794 | 166 794 | 30. 6. 2024 |
1,37602 % | Global X Investments Canada Inc. | 165 673 | 137 515 | 30. 9. 2024 |
1,24909 % | Walleye Capital LLC | 150 391 | 17 807 | 30. 6. 2024 |
1,16528 % | Schonfeld Strategic Advisors LLC | 140 300 | 16 027 | 30. 6. 2024 |
1,01953 % | Millennium Management LLC | 122 751 | -118 898 | 30. 9. 2024 |
0,96571 % | ExodusPoint Capital Management, LP | 116 271 | 116 271 | 30. 6. 2024 |
0,84285 % | StemPoint Capital LP | 101 479 | 101 479 | 30. 6. 2024 |
0,83056 % | Integral Health Asset Management, LLC | 100 000 | 100 000 | 30. 6. 2024 |
0,76186 % | Barclays Bank PLC | 91 728 | -93 420 | 30. 6. 2024 |
0,71718 % | Boothbay Fund Management, LLC | 86 349 | -69 664 | 30. 6. 2024 |
0,70424 % | Exome Asset Management LLC | 84 790 | -3 056 | 30. 6. 2024 |
0,60500 % | Verition Fund Management LLC | 72 842 | 72 842 | 30. 6. 2024 |
0,53574 % | Schroder Investment Management Ltd. (SIM) | 64 503 | 0 | 30. 6. 2024 |
0,53571 % | Acuta Capital Partners, LLC | 64 500 | 64 500 | 30. 6. 2024 |
0,52375 % | Driehaus Capital Management, LLC | 63 059 | 0 | 30. 6. 2024 |
0,50272 % | Goldman Sachs & Company, Inc. | 60 528 | -45 850 | 30. 6. 2024 |
0,46900 % | Superstring Capital Management LP | 56 468 | 56 468 | 30. 6. 2024 |
0,44092 % | BofA Global Research (US) | 53 087 | 25 092 | 30. 6. 2024 |
0,42590 % | Wellington Management Company, LLP | 51 278 | 51 278 | 30. 6. 2024 |
0,41528 % | Smethurst (Dominic) | 50 000 | 50 000 | 27. 2. 2024 |
0,40708 % | Cinctive Capital Management LP | 49 013 | 49 013 | 30. 6. 2024 |
0,37678 % | Ensign Peak Advisors, Inc. | 45 364 | -22 136 | 30. 6. 2024 |
0,36674 % | Wexford Capital LP | 44 156 | 44 156 | 30. 6. 2024 |
0,35714 % | Hudson Bay Capital Management LP | 43 000 | 0 | 30. 6. 2024 |
0,33887 % | TD Asset Management Inc. | 40 800 | 19 600 | 30. 6. 2024 |
0,32475 % | Healthinvest Partners AB | 39 100 | 1 100 | 30. 6. 2024 |
0,32220 % | HighVista Strategies LLC | 38 793 | 38 793 | 30. 6. 2024 |
0,30278 % | NEOS Investment Management, LLC | 36 455 | 36 455 | 30. 6. 2024 |
0,27545 % | Trexquant Investment LP | 33 164 | 21 180 | 30. 6. 2024 |
0,25020 % | Mirae Asset Global Investments (USA) LLC | 30 124 | 5 244 | 30. 6. 2024 |
0,23956 % | Charles Schwab Investment Management, Inc. | 28 843 | 24 030 | 30. 6. 2024 |
0,23904 % | BlackRock Investment Management, LLC | 28 780 | 27 038 | 30. 6. 2024 |
0,23171 % | Nuveen LLC | 27 898 | 27 898 | 30. 6. 2024 |
0,22337 % | abrdn Inc. | 26 894 | 21 751 | 30. 9. 2024 |
0,22222 % | BlackRock Financial Management, Inc. | 26 755 | 25 521 | 30. 6. 2024 |
0,21400 % | Northern Trust Investments, Inc. | 25 765 | 5 764 | 30. 6. 2024 |
0,19279 % | Rafferty Asset Management LLC | 23 212 | 23 212 | 30. 6. 2024 |
0,18475 % | BNY Mellon Asset Management | 22 244 | 22 244 | 30. 6. 2024 |
0,17981 % | UBS Financial Services, Inc. | 21 649 | 6 184 | 30. 6. 2024 |
0,17551 % | Manulife Investment Management (North America) Limited | 21 131 | 10 604 | 30. 6. 2024 |
0,17110 % | Zimmer Partners, LP | 20 600 | 20 600 | 30. 6. 2024 |
0,16611 % | Artia Global Partners LP | 20 000 | 20 000 | 30. 6. 2024 |
0,15831 % | Victory Capital Management Inc. | 19 060 | 19 060 | 30. 6. 2024 |
0,14079 % | Florida State Board of Administration | 16 951 | 16 951 | 30. 6. 2024 |
0,13351 % | Dimensional Fund Advisors, L.P. | 16 075 | 0 | 30. 6. 2024 |
0,13306 % | ClariVest Asset Management LLC | 16 021 | 16 021 | 30. 6. 2024 |
0,13168 % | Acadian Asset Management LLC | 15 854 | 15 854 | 30. 6. 2024 |
0,12458 % | Jefferies LLC | 15 000 | 3 900 | 30. 6. 2024 |
0,11998 % | Prelude Capital Management, LLC | 14 446 | -3 500 | 30. 6. 2024 |
0,11713 % | Rhumbline Advisers Ltd. Partnership | 14 103 | 14 103 | 30. 6. 2024 |
0,10473 % | EAM Investors, LLC | 12 609 | 12 609 | 30. 6. 2024 |
0,10193 % | Jump Financial, LLC | 12 272 | 12 272 | 30. 6. 2024 |
0,09967 % | Adar1 Capital Management LLC | 12 000 | -4 000 | 30. 6. 2024 |
0,09480 % | Columbia Threadneedle Investments (US) | 11 414 | 11 414 | 30. 6. 2024 |
0,09409 % | Gilder Gagnon Howe & Co. LLC | 11 328 | 11 328 | 30. 6. 2024 |
0,08548 % | Jane Street Capital, L.L.C. | 10 292 | -22 108 | 30. 6. 2024 |
0,07757 % | MFS Investment Management | 9 340 | 1 190 | 31. 8. 2024 |
0,07001 % | Moran (Sean F) | 8 429 | 0 | 18. 6. 2024 |
0,06638 % | Mellon Investments Corporation | 7 992 | 7 992 | 30. 6. 2024 |
0,06264 % | Fidelity Management & Research Company LLC | 7 542 | -1 612 | 30. 6. 2024 |
0,06089 % | SG Americas Securities, L.L.C. | 7 331 | 7 331 | 30. 9. 2024 |
0,05988 % | AllianceBernstein L.P. | 7 210 | 7 210 | 30. 6. 2024 |
0,05744 % | T. Rowe Price International Ltd | 6 916 | 4 252 | 30. 6. 2024 |
0,05455 % | GWM Advisors LLC | 6 568 | 6 560 | 30. 6. 2024 |
0,04849 % | Susquehanna International Group, LLP | 5 838 | 5 838 | 30. 6. 2024 |
0,04841 % | Holmer (Alan F) | 5 829 | 1 667 | 14. 6. 2024 |
0,04623 % | Kung (Winston) | 5 566 | 5 566 | 16. 8. 2024 |
0,04541 % | Corebridge Financial Inc | 5 467 | 5 467 | 30. 6. 2024 |
0,04541 % | SunAmerica Asset Management, LLC | 5 467 | 0 | 31. 7. 2024 |
0,04058 % | Goldman Sachs Asset Management, L.P. | 4 886 | 1 641 | 30. 9. 2024 |
0,03817 % | Invesco Advisers, Inc. | 4 596 | 4 596 | 30. 6. 2024 |
0,03640 % | Citi Investment Research (US) | 4 383 | -10 924 | 30. 6. 2024 |
0,03613 % | Catlin (Avery W) | 4 350 | 2 783 | 30. 5. 2024 |
0,03597 % | JPMorgan Private Bank (United States) | 4 331 | 4 331 | 30. 6. 2024 |
0,03405 % | New York State Common Retirement Fund | 4 100 | 0 | 30. 9. 2024 |
0,03341 % | DWS Investments UK Limited | 4 022 | 4 022 | 30. 6. 2024 |