14,83625 % | Vivo Capital, LLC | 5 766 851 | -1 550 000 | 29. 8. 2024 |
10,71180 % | Janus Henderson Investors | 4 163 678 | 804 805 | 30. 9. 2024 |
8,24537 % | Perceptive Advisors LLC | 3 204 976 | 130 434 | 30. 6. 2024 |
7,92927 % | Nantahala Capital Management, LLC | 3 082 107 | 671 728 | 30. 6. 2024 |
7,34267 % | Adage Capital Management, L.P. | 2 854 094 | 910 574 | 30. 6. 2024 |
5,38118 % | Avoro Capital Advisors LLC | 2 091 666 | 466 666 | 30. 6. 2024 |
3,85717 % | The Vanguard Group, Inc. | 1 499 283 | 533 098 | 30. 6. 2024 |
3,66607 % | Commodore Capital LP | 1 425 000 | 1 255 467 | 30. 6. 2024 |
3,63940 % | BlackRock Institutional Trust Company, N.A. | 1 414 633 | 1 115 437 | 30. 6. 2024 |
3,08721 % | Vestal Point Capital, LP | 1 200 000 | -50 000 | 30. 6. 2024 |
2,57303 % | State Street Global Advisors (US) | 1 000 136 | 29 566 | 30. 6. 2024 |
2,25281 % | Frazier Life Sciences Management, L.P. | 875 667 | 0 | 30. 6. 2024 |
1,86746 % | Abingworth Management Limited | 725 881 | -2 131 923 | 17. 10. 2024 |
1,61059 % | Anish (Bhatnagar) | 626 035 | -21 633 | 1. 10. 2024 |
1,42619 % | Sofinnova Investments, Inc | 554 359 | 403 584 | 30. 6. 2024 |
1,41497 % | TCG Crossover Management, LLC | 550 000 | 0 | 30. 6. 2024 |
1,40556 % | Emerald Advisers LLC | 546 342 | 11 915 | 30. 9. 2024 |
1,38012 % | Holocene Advisors, LP | 536 451 | 536 451 | 30. 6. 2024 |
1,28904 % | Samlyn Capital, LLC | 501 049 | 282 122 | 30. 6. 2024 |
1,25831 % | Geode Capital Management, L.L.C. | 489 107 | 322 086 | 30. 6. 2024 |
1,18797 % | T. Rowe Price Associates, Inc. | 461 762 | 309 142 | 30. 6. 2024 |
1,17962 % | Millennium Management LLC | 458 520 | 366 295 | 30. 6. 2024 |
1,14600 % | Ikarian Capital LLC | 445 451 | -119 960 | 30. 6. 2024 |
1,11078 % | Pictet Asset Management Ltd. | 431 760 | 97 908 | 30. 6. 2024 |
1,01115 % | Wellington Management Company, LLP | 393 035 | 39 554 | 30. 6. 2024 |
0,86471 % | BlackRock Financial Management, Inc. | 336 114 | 330 723 | 30. 6. 2024 |
0,82121 % | Woodline Partners LP | 319 205 | 212 745 | 30. 6. 2024 |
0,77180 % | Ghost Tree Capital, LLC | 300 000 | 100 000 | 30. 6. 2024 |
0,73620 % | Ally Bridge Group NY LLC | 286 162 | -50 324 | 30. 6. 2024 |
0,63600 % | Balyasny Asset Management LP | 247 214 | 95 596 | 30. 6. 2024 |
0,55008 % | Mario (Ernest B) | 213 818 | 6 500 | 6. 6. 2024 |
0,54775 % | Altium Capital Management LP | 212 909 | 60 000 | 30. 6. 2024 |
0,51721 % | Goldman Sachs & Company, Inc. | 201 038 | -10 879 | 30. 6. 2024 |
0,50771 % | Medical Strategy GmbH | 197 347 | 25 000 | 30. 6. 2024 |
0,37357 % | Schuler (Jack W) | 145 207 | -372 143 | 24. 5. 2023 |
0,37332 % | Driehaus Capital Management, LLC | 145 110 | 51 656 | 30. 6. 2024 |
0,36384 % | Allspring Global Investments, LLC | 141 424 | 7 840 | 30. 9. 2024 |
0,28299 % | Soros Fund Management, L.L.C. | 110 000 | 10 000 | 30. 6. 2024 |
0,26761 % | Boothbay Fund Management, LLC | 104 020 | -28 011 | 30. 6. 2024 |
0,24292 % | Artia Global Partners LP | 94 424 | 53 500 | 30. 6. 2024 |
0,23303 % | Principal Global Investors (Equity) | 90 580 | -6 483 | 31. 8. 2024 |
0,21540 % | Caption Management, LLC | 83 726 | 43 726 | 30. 6. 2024 |
0,21532 % | Morgan Stanley & Co. LLC | 83 696 | 4 509 | 30. 6. 2024 |
0,21393 % | Hirano (Patricia C) | 83 153 | -3 108 | 1. 10. 2024 |
0,21185 % | Mackaness (James H) | 82 348 | -8 077 | 1. 10. 2024 |
0,20959 % | Yen (Kristen) | 81 466 | -3 108 | 1. 10. 2024 |
0,19166 % | Polar Asset Management Partners Inc. | 74 500 | 74 500 | 30. 6. 2024 |
0,18009 % | 683 Capital Management LLC | 70 000 | -8 000 | 30. 6. 2024 |
0,17137 % | BofA Global Research (US) | 66 612 | -2 346 | 30. 6. 2024 |
0,16173 % | BlackRock Investment Management, LLC | 62 863 | 62 863 | 30. 6. 2024 |
0,16084 % | Charles Schwab Investment Management, Inc. | 62 517 | 55 322 | 30. 6. 2024 |
0,15040 % | Nuveen LLC | 58 460 | 58 460 | 30. 6. 2024 |
0,14862 % | Norges Bank Investment Management (NBIM) | 57 770 | 57 770 | 30. 6. 2024 |
0,14802 % | TD Asset Management Inc. | 57 534 | 36 534 | 30. 6. 2024 |
0,14488 % | Qube Research & Technologies Ltd | 56 316 | -22 184 | 30. 6. 2024 |
0,14401 % | Northern Trust Investments, Inc. | 55 978 | 22 401 | 30. 6. 2024 |
0,14383 % | BNY Mellon Asset Management | 55 906 | 55 906 | 30. 6. 2024 |
0,13897 % | Schonfeld Strategic Advisors LLC | 54 019 | 8 547 | 30. 6. 2024 |
0,13876 % | Rafferty Asset Management LLC | 53 937 | -52 207 | 30. 6. 2024 |
0,12711 % | Manulife Investment Management (North America) Limited | 49 408 | 27 020 | 30. 6. 2024 |
0,10291 % | Manning (Meredith S.) | 40 000 | 40 000 | 17. 7. 2024 |
0,10272 % | Adar1 Capital Management LLC | 39 929 | 39 929 | 30. 6. 2024 |
0,10081 % | Susquehanna International Group, LLP | 39 184 | 30 162 | 30. 6. 2024 |
0,09274 % | Harbor Capital Advisors, Inc. | 36 048 | 34 807 | 30. 9. 2024 |
0,09028 % | Jefferies LLC | 35 091 | -800 | 30. 6. 2024 |
0,09004 % | Huang (Michael F) | 35 000 | 35 000 | 17. 7. 2024 |
0,08734 % | UBS Financial Services, Inc. | 33 950 | -19 855 | 30. 6. 2024 |
0,08650 % | Columbia Threadneedle Investments (US) | 33 624 | 2 484 | 30. 6. 2024 |
0,08453 % | Mellon Investments Corporation | 32 858 | 32 858 | 30. 6. 2024 |
0,08117 % | MFS Investment Management | 31 550 | 0 | 31. 8. 2024 |
0,08082 % | BlackRock Investment Management (UK) Ltd. | 31 414 | 25 044 | 30. 6. 2024 |
0,07718 % | Hudson Bay Capital Management LP | 30 000 | 30 000 | 30. 6. 2024 |
0,07498 % | Rhumbline Advisers Ltd. Partnership | 29 144 | 29 144 | 30. 6. 2024 |
0,07409 % | Schweizerische Nationalbank | 28 800 | -1 300 | 30. 6. 2024 |
0,07307 % | Alps Advisors, Inc. | 28 401 | 6 887 | 30. 6. 2024 |
0,06930 % | J. Goldman & Co., L.P. | 26 938 | 26 938 | 30. 6. 2024 |
0,06432 % | Maplelane Capital, LLC | 25 000 | 0 | 30. 6. 2024 |
0,06331 % | AllianceBernstein L.P. | 24 610 | 24 610 | 30. 6. 2024 |
0,05423 % | Barclays Bank PLC | 21 078 | 459 | 30. 6. 2024 |
0,05357 % | Alpine Global Management, LLC | 20 824 | 20 824 | 30. 6. 2024 |
0,05067 % | Checkpoint Capital L.P. | 19 695 | 19 695 | 30. 6. 2024 |
0,04623 % | BlackRock Asset Management Ireland Limited | 17 970 | 2 629 | 30. 6. 2024 |
0,04554 % | Tudor Investment Corporation | 17 702 | 1 508 | 30. 6. 2024 |
0,04490 % | Legal & General Investment Management Ltd. | 17 452 | 5 169 | 30. 6. 2024 |
0,04139 % | T. Rowe Price International Ltd | 16 090 | 11 228 | 30. 6. 2024 |
0,03962 % | Harris (William G) | 15 401 | 6 500 | 6. 6. 2024 |
0,03859 % | SilverArc Capital Management, LLC | 15 000 | 15 000 | 30. 6. 2024 |
0,03859 % | UBS O'Connor LLC | 15 000 | 15 000 | 30. 6. 2024 |
0,03815 % | California State Teachers Retirement System | 14 827 | 1 047 | 30. 6. 2024 |
0,03620 % | Jane Street Capital, L.L.C. | 14 070 | -768 | 30. 6. 2024 |
0,03485 % | Volck (Birgitte) | 13 545 | 6 500 | 6. 6. 2024 |
0,03393 % | Cinctive Capital Management LP | 13 190 | 13 190 | 30. 6. 2024 |
0,03344 % | Bir (Dawn Carter) | 13 000 | 13 000 | 15. 8. 2024 |
0,03332 % | NEOS Investment Management, LLC | 12 950 | 1 311 | 30. 6. 2024 |
0,03120 % | Aspiriant, LLC | 12 128 | 0 | 30. 9. 2024 |
0,03044 % | SunAmerica Asset Management, LLC | 11 832 | 0 | 31. 7. 2024 |
0,03044 % | Corebridge Financial Inc | 11 832 | 11 832 | 30. 6. 2024 |
0,02817 % | Citi Investment Research (US) | 10 948 | -86 806 | 30. 6. 2024 |
0,02760 % | Victory Capital Management Inc. | 10 727 | 2 236 | 30. 6. 2024 |
0,02733 % | Invesco Advisers, Inc. | 10 625 | 10 262 | 30. 6. 2024 |