18,65370 % | VenBio Partners LLC | 9 699 925 | 0 | 31. 3. 2025 |
8,65385 % | HBM Partners AG | 4 500 000 | 1 073 071 | 31. 3. 2025 |
7,00160 % | Redmile Group, LLC | 3 640 834 | -48 777 | 31. 3. 2025 |
6,07359 % | Tang Capital Management, LLC | 3 158 265 | -138 618 | 31. 3. 2025 |
5,67227 % | Lightstone Ventures, L.P. | 2 949 580 | 0 | 31. 3. 2025 |
4,05053 % | BlackRock Institutional Trust Company, N.A. | 2 106 278 | -67 145 | 31. 3. 2025 |
3,53447 % | The Vanguard Group, Inc. | 1 837 923 | -49 079 | 31. 3. 2025 |
2,79188 % | BofA Global Research (US) | 1 451 778 | 416 452 | 31. 3. 2025 |
2,60219 % | Almitas Capital LLC | 1 353 141 | 130 196 | 31. 3. 2025 |
2,49294 % | Acadian Asset Management LLC | 1 296 331 | 186 883 | 31. 3. 2025 |
2,35318 % | Two Sigma Investments, LP | 1 223 655 | -304 376 | 31. 3. 2025 |
1,81555 % | Millennium Management LLC | 944 084 | -1 185 026 | 31. 3. 2025 |
1,48251 % | Geode Capital Management, L.L.C. | 770 907 | 30 801 | 31. 3. 2025 |
1,38241 % | State Street Global Advisors (US) | 718 853 | 34 730 | 31. 3. 2025 |
1,28605 % | BMO Capital Markets (US) | 668 747 | 59 379 | 31. 3. 2025 |
1,05769 % | MPM BioImpact LLC | 550 000 | -841 434 | 31. 3. 2025 |
0,97896 % | Privium Fund Management BV | 509 059 | 0 | 31. 3. 2025 |
0,91060 % | Pons (Jaume) | 473 513 | 48 250 | 31. 3. 2025 |
0,78834 % | Los Angeles Capital Management LLC | 409 938 | 108 519 | 31. 3. 2025 |
0,64587 % | J.P. Morgan Securities LLC | 335 853 | 120 768 | 31. 3. 2025 |
0,63711 % | Morgan Stanley & Co. LLC | 331 299 | -1 910 633 | 31. 3. 2025 |
0,60053 % | Northern Trust Investments, Inc. | 312 278 | -30 742 | 31. 3. 2025 |
0,52193 % | Randolph (Sophia) | 271 405 | 28 569 | 31. 3. 2025 |
0,52153 % | Marshall Wace LLP | 271 197 | 271 197 | 31. 3. 2025 |
0,49326 % | UBS Financial Services, Inc. | 256 493 | -151 563 | 31. 3. 2025 |
0,46841 % | Goldman Sachs & Company, Inc. | 243 572 | -116 926 | 31. 3. 2025 |
0,40587 % | Charles Schwab Investment Management, Inc. | 211 051 | -5 656 | 31. 3. 2025 |
0,32187 % | Goodman (Corey S) | 167 370 | 0 | 31. 3. 2025 |
0,29572 % | Commonwealth Financial Network | 153 777 | 136 868 | 31. 3. 2025 |
0,28265 % | Qube Research & Technologies Ltd | 146 977 | 8 507 | 31. 3. 2025 |
0,24931 % | Goldman Sachs Asset Management, L.P. | 129 642 | -78 869 | 31. 3. 2025 |
0,24090 % | Lettmann (Jason) | 125 270 | 18 000 | 31. 3. 2025 |
0,23762 % | LSV Asset Management | 123 560 | 35 840 | 30. 4. 2025 |
0,23406 % | Susquehanna International Group, LLP | 121 710 | -29 910 | 31. 3. 2025 |
0,23077 % | Klencke (Barbara M.D.) | 120 000 | 60 000 | 31. 3. 2025 |
0,22894 % | AQR Capital Management, LLC | 119 050 | 77 065 | 31. 3. 2025 |
0,22555 % | BlackRock Financial Management, Inc. | 117 284 | 1 855 | 31. 3. 2025 |
0,21499 % | Florida State Board of Administration | 111 793 | 0 | 31. 3. 2025 |
0,20357 % | Bank of Nova Scotia | 105 858 | 552 | 31. 3. 2025 |
0,19999 % | Nuveen LLC | 103 995 | 0 | 31. 3. 2025 |
0,19284 % | DWS Investments UK Limited | 100 276 | 0 | 31. 3. 2025 |
0,17742 % | XTX Markets LLC | 92 259 | -171 597 | 31. 3. 2025 |
0,17050 % | BlackRock Investment Management, LLC | 88 660 | -4 937 | 31. 3. 2025 |
0,14843 % | Garcia (Peter S) | 77 185 | 28 512 | 31. 3. 2025 |
0,14596 % | D. E. Shaw & Co., L.P. | 75 900 | -179 978 | 31. 3. 2025 |
0,14199 % | Invesco Advisers, Inc. | 73 836 | 73 836 | 31. 3. 2025 |
0,13794 % | AllianceBernstein L.P. | 71 730 | 0 | 31. 3. 2025 |
0,13178 % | BNY Mellon Asset Management | 68 523 | -804 | 31. 3. 2025 |
0,12733 % | abrdn Inc. | 66 211 | 0 | 31. 3. 2025 |
0,11691 % | SEI Investments Management Corporation | 60 795 | 0 | 31. 3. 2025 |
0,11691 % | Nuveen Asset Management, LLC | 60 795 | 0 | 31. 3. 2025 |
0,09236 % | Barclays Bank PLC | 48 029 | -17 093 | 31. 3. 2025 |
0,08904 % | Rhumbline Advisers Ltd. Partnership | 46 302 | 3 786 | 31. 3. 2025 |
0,08313 % | Pinto (Shelly) | 43 227 | 11 379 | 31. 3. 2025 |
0,08067 % | Nan Fung Life Sciences | 41 950 | 0 | 31. 3. 2025 |
0,07885 % | Deka Investment GmbH | 41 000 | 16 700 | 31. 12. 2023 |
0,07885 % | Deka Vermögensmanagement GmbH | 41 000 | 0 | 31. 12. 2024 |
0,07798 % | Wealth Enhancement Advisory Services, LLC | 40 551 | 1 420 | 31. 3. 2025 |
0,06649 % | Vanguard Personalized Indexing Management, LLC | 34 577 | -8 479 | 31. 3. 2025 |
0,06346 % | Hemrajani (Rekha) | 33 000 | 30 000 | 31. 3. 2025 |
0,06174 % | INTECH Investment Management LLC | 32 106 | 18 908 | 31. 3. 2025 |
0,06042 % | The Financial Advisory Group, Inc | 31 417 | 0 | 31. 3. 2024 |
0,05574 % | Avantis Investors | 28 985 | 8 467 | 31. 3. 2024 |
0,04752 % | Citi Investment Research (US) | 24 711 | -6 725 | 31. 3. 2025 |
0,04284 % | SG Americas Securities, L.L.C. | 22 277 | -1 979 | 31. 3. 2025 |
0,04241 % | Forum Financial Management, LP | 22 051 | 10 752 | 31. 3. 2025 |
0,04228 % | Fidelity Management & Research Company LLC | 21 988 | -1 651 878 | 31. 3. 2025 |
0,04219 % | Parametric Portfolio Associates LLC | 21 940 | -230 261 | 31. 3. 2025 |
0,04135 % | HC Advisors, LLC | 21 500 | 6 025 | 31. 3. 2025 |
0,03976 % | Mellon Investments Corporation | 20 676 | 0 | 31. 3. 2025 |
0,03802 % | Mirae Asset Global Investments (USA) LLC | 19 771 | 858 | 31. 3. 2025 |
0,03654 % | Kazazian Asset Management, LLC | 19 000 | 19 000 | 31. 3. 2025 |
0,03516 % | Mercer Global Investments Management Ltd | 18 284 | -27 548 | 30. 4. 2025 |
0,03365 % | JSF Financial, LLC | 17 500 | 0 | 31. 3. 2025 |
0,03286 % | Group One Trading, L.P. | 17 085 | 1 973 | 31. 3. 2025 |
0,03246 % | Corebridge Financial Inc. | 16 878 | -251 | 31. 3. 2025 |
0,03166 % | Wells Fargo Bank, N.A. | 16 461 | 362 | 31. 3. 2025 |
0,03133 % | JPMorgan Private Bank (United States) | 16 293 | 1 143 | 31. 3. 2025 |
0,03102 % | HSBC Global Asset Management (UK) Limited | 16 128 | -26 | 31. 3. 2025 |
0,02922 % | Moneta Group Investment Advisors, LLC | 15 196 | 0 | 31. 3. 2025 |
0,02750 % | Renaissance Technologies LLC | 14 299 | 14 299 | 31. 3. 2025 |
0,02624 % | BMO Family Office, LLC | 13 647 | -203 567 | 31. 3. 2025 |
0,02542 % | Lido Advisors, LLC | 13 220 | 0 | 31. 3. 2025 |
0,02408 % | New York State Common Retirement Fund | 12 522 | 0 | 31. 3. 2025 |
0,02043 % | T. Rowe Price International Ltd | 10 622 | 0 | 31. 3. 2025 |
0,02023 % | Tower Research Capital LLC | 10 517 | 5 516 | 31. 3. 2025 |
0,01938 % | Mercer Global Advisors, Inc. | 10 077 | 10 077 | 31. 3. 2025 |
0,01538 % | Abaris Investment Management AG | 8 000 | -8 000 | 30. 6. 2024 |
0,01460 % | BNP Paribas Securities Corp. North America | 7 590 | -3 827 | 31. 3. 2025 |
0,01316 % | Carson Wealth Management Group | 6 845 | 4 641 | 31. 3. 2025 |
0,01258 % | Federated MDTA LLC | 6 541 | 2 058 | 31. 3. 2025 |
0,01182 % | Police and Firemen's Retirement System of New Jersey | 6 148 | 0 | 31. 3. 2025 |
0,01154 % | ProShare Advisors LLC | 6 001 | 190 | 31. 5. 2025 |
0,01136 % | Northern Trust Global Investments | 5 905 | 0 | 31. 3. 2025 |
0,01118 % | J.P. Morgan Securities plc | 5 811 | 0 | 31. 3. 2025 |
0,01100 % | Principal Global Investors (Equity) | 5 721 | 0 | 30. 4. 2025 |
0,00950 % | BlackRock Advisors, LLC | 4 942 | 0 | 31. 12. 2024 |
0,00942 % | Morgan Stanley Investment Management Inc. (US) | 4 896 | 0 | 31. 3. 2025 |
0,00934 % | BlackRock Fund Advisors | 4 859 | 788 | 31. 12. 2024 |
0,00889 % | Dimensional Fund Advisors, Ltd. | 4 625 | -16 176 | 31. 3. 2025 |