٧٫٧٩ % | RA Capital Management, LP | ٤٦٬٢٠٢٬٤٢٥ | 0 | ٣١/١٢/٢٠٢٣ |
٦٫٤١ % | BlackRock Institutional Trust Company, N.A. | ٣٨٬٠٤٢٬٦٢١ | ٤٬٩٤١٬٦٠٧ | ٣١/١٢/٢٠٢٣ |
٤٫٩٩ % | Deep Track Capital LP | ٢٩٬٥٨٣٬٤٤٩ | ٣٬٨٨٣٬٤٤٩ | ٣١/١٢/٢٠٢٣ |
٤٫٨٠ % | The Vanguard Group, Inc. | ٢٨٬٤٧٥٬٢١٢ | ١٬٩١٤٬٣٢٨ | ٣١/١٢/٢٠٢٣ |
٤٫٣٢ % | State Street Global Advisors (US) | ٢٥٬٦٢٥٬٦٠٦ | ٢٥٤٬٢٢١ | ٣١/١٢/٢٠٢٣ |
٤٫٠٧ % | Vivo Capital, LLC | ٢٤٬١٤٣٬٦٨١ | ٧٬٦١٩٬٠٤٧ | ٣١/١٢/٢٠٢٣ |
٣٫٩٤ % | TCG Crossover Management, LLC | ٢٣٬٣٧٥٬٨٣٩ | 0 | ٣١/١٢/٢٠٢٣ |
٣٫٨٤ % | New Enterprise Associates (NEA) | ٢٢٬٧٧٦٬٤٠٩ | 0 | ٣١/١٢/٢٠٢٣ |
٢٫٤٨ % | Millennium Management LLC | ١٤٬٧٣٠٬٩٨٦ | -١٬٣٤٢٬١٢٠ | ٣١/١٢/٢٠٢٣ |
١٫٨٥ % | Geode Capital Management, L.L.C. | ١٠٬٩٤٣٬٦٤٩ | ٩٣٠٬٧٤٧ | ٣١/١٢/٢٠٢٣ |
١٫٨١ % | BioImpact Capital LLC | ١٠٬٧١٥٬٦٢٠ | ٣٬١٣٩ | ٣١/١٢/٢٠٢٣ |
١٫٧٤ % | Morgan Stanley & Co. LLC | ١٠٬٣٠٢٬٠٦٨ | ٩٬١٥٧٬٨٢٢ | ٣١/١٢/٢٠٢٣ |
١٫٦٠ % | Wellington Management Company, LLP | ٩٬٤٨٤٬٩٧١ | -٩٢٠٬٦٥٥ | ٣١/١٢/٢٠٢٣ |
١٫٤٩ % | Sofinnova Investments, Inc | ٨٬٨١٤٬٤٩٧ | ٥٬١١١٬٩٥١ | ٣١/١٢/٢٠٢٣ |
١٫١٩ % | Fidelity Management & Research Company LLC | ٧٬٠٣٢٬٣٥٢ | -٥٢٨٬٧١٤ | ٣١/١٢/٢٠٢٣ |
١٫١٥ % | DWS Investment S.A. | ٦٬٨٢٦٬٥٩٩ | ٦٬٨٢٦٬٥٩٩ | ٣١/١٢/٢٠٢٣ |
٠٫٧٥ % | Northern Trust Investments, Inc. | ٤٬٤٢٩٬٣٧٦ | ٢٣٩٬٩٧٥ | ٣١/١٢/٢٠٢٣ |
٠٫٧٥ % | Segall Bryant & Hamill, LLC | ٤٬٤١٩٬٨٢٠ | -٥٧٠٬٦٧٩ | ٣١/١٢/٢٠٢٣ |
٠٫٧٠ % | Invesco Capital Management LLC | ٤٬١٧١٬٥٤٦ | -١٨٤٬٠٩٣ | ٣١/١٢/٢٠٢٣ |
٠٫٦٥ % | Charles Schwab Investment Management, Inc. | ٣٬٨٤٢٬٥٠٠ | ٢٠٨٬١٧٠ | ٣١/١٢/٢٠٢٣ |
٠٫٥٦ % | Armistice Capital LLC | ٣٬٢٩٦٬٠٠٠ | -٣٢٨٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٥١ % | Boxer Capital, L.L.C. | ٣٬٠٠٠٬٠٠٠ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٥٠ % | Ally Bridge Group NY LLC | ٢٬٩٧١٬٦٣٩ | ٧٥٠٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٤٧ % | Goldman Sachs & Company, Inc. | ٢٬٧٧٠٬٩٦٦ | -٣٢٥٬٩٤٦ | ٣١/١٢/٢٠٢٣ |
٠٫٣٥ % | Marshall Wace LLP | ٢٬٠٧٨٬٤٩٧ | -٣٬٧٨٢٬١٤٨ | ٣١/١٢/٢٠٢٣ |
٠٫٢٨ % | Rafferty Asset Management LLC | ١٬٦٦٩٬٠٨٧ | -٢٣٣٬١٧٩ | ٣١/١٢/٢٠٢٣ |
٠٫٢٧ % | Medical Strategy GmbH | ١٬٦١٨٬٢٦٣ | -٢١٦٬٦٦٣ | ٣١/١٢/٢٠٢٣ |
٠٫٢٧ % | Barclays Bank PLC | ١٬٥٧٥٬٥٨٥ | ١١٬٢٣٦ | ٣١/١٢/٢٠٢٣ |
٠٫٢٥ % | Nuveen LLC | ١٬٤٧٣٬٤٤٢ | ٧٬٧٢٨ | ٣١/١٢/٢٠٢٣ |
٠٫٢٤ % | UBS Financial Services, Inc. | ١٬٤٤١٬٦٠٣ | ٧٩٠٬٤٢٣ | ٣١/١٢/٢٠٢٣ |
٠٫٢٣ % | BNY Mellon Asset Management | ١٬٣٦١٬٠٧٤ | ٩٤٬٠٩٧ | ٣١/١٢/٢٠٢٣ |
٠٫٢٢ % | BlackRock Financial Management, Inc. | ١٬٣٢٣٬٣٠٤ | ٤٬٠٦١ | ٣١/١٢/٢٠٢٣ |
٠٫٢٢ % | MML Investors Services, LLC | ١٬٢٩٥٬٢٢٨ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٢٢ % | Walleye Capital LLC | ١٬٢٧٥٬٥١٤ | -٩٥٠٬٥٥٢ | ٣١/١٢/٢٠٢٣ |
٠٫٢١ % | BlackRock Investment Management, LLC | ١٬٢٥٠٬٢٧٨ | ١٢٬٨٦٥ | ٣١/١٢/٢٠٢٣ |
٠٫٢١ % | Russell Investments Trust Company | ١٬٢٣٧٬٢٣٤ | ٢٠٤٬٧٦٥ | ٣١/١٢/٢٠٢٣ |
٠٫٢٠ % | JP Morgan Asset Management | ١٬١٩٧٬٩٥٦ | -٢٣٦٬٢٨٩ | ٣١/١٢/٢٠٢٣ |
٠٫١٩ % | Kennedy Capital Management LLC | ١٬١٣٥٬١٩٥ | ١٬١٣٥٬١٩٥ | ٣١/١٢/٢٠٢٣ |
٠٫١٧ % | BlackRock Advisors (UK) Limited | ٩٨٩٬٥٢٠ | ٣٤٬٩٤١ | ٣١/٣/٢٠٢٤ |
٠٫١٥ % | Nan Fung Life Sciences | ٩١٣٬٥٥٠ | ١٦٠٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٤ % | BlackRock Asset Management Ireland Limited | ٨٢٨٬٥٩٨ | ٤٨٬٤٤٣ | ٣١/١٢/٢٠٢٣ |
٠٫١٣ % | Velan Capital Investment Management LP | ٧٧٨٬٥٠٠ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫١٣ % | Schweizerische Nationalbank | ٧٧٣٬٦٠٠ | -٢٣٢٬٩٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٢ % | BNP Paribas Securities Corp. North America | ٧١٤٬٠١٢ | ١٩٦٬٣٢٨ | ٣١/١٢/٢٠٢٣ |
٠٫١٢ % | Citi Investment Research (US) | ٧١١٬٩٤٩ | -٩٣٬٩٦٢ | ٣١/١٢/٢٠٢٣ |
٠٫١٢ % | Rhumbline Advisers Ltd. Partnership | ٧٠٩٬١٤٣ | ٣٬١٥٧ | ٣١/١٢/٢٠٢٣ |
٠٫١٢ % | Susquehanna International Group, LLP | ٦٩٩٬٤٤٣ | ٢٢٧٬٦٣٤ | ٣١/١٢/٢٠٢٣ |
٠٫١٢ % | Crestline Investors, Inc. | ٦٨٧٬٣٧٨ | ١٠٢٬٢٢٧ | ٣١/١٢/٢٠٢٣ |
٠٫١١ % | Credit Suisse Funds AG | ٦٦٩٬١٢٨ | ٢٥٬٧٤٥ | ٣١/١٢/٢٠٢٣ |
٠٫١١ % | Citadel Advisors LLC | ٦٤٣٬١٦٤ | ٢٥١٬٤٥٥ | ٣١/١٢/٢٠٢٣ |
٠٫١٠ % | Columbia Threadneedle Investments (US) | ٦١٧٬٣٦٣ | ١٣٬٢٦٢ | ٣١/١٢/٢٠٢٣ |
٠٫١٠ % | Jane Street Capital, L.L.C. | ٦١٣٬٤١٥ | ٤٢٥٬٠٦٣ | ٣١/١٢/٢٠٢٣ |
٠٫١٠ % | Exome Asset Management LLC | ٦٠٧٬٥٠٠ | ٦٠٧٬٥٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٩ % | BofA Global Research (US) | ٥٤٦٬٧٩٦ | -٦٥٧٬٢٧٣ | ٣١/١٢/٢٠٢٣ |
٠٫٠٩ % | AllianceBernstein L.P. | ٥١٢٬٧٤١ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٠٨ % | HealthCor Management, L.P. | ٥٠٠٬٠٠٠ | -١٬٤٠٤٬٢٣٤ | ٣١/١٢/٢٠٢٢ |
٠٫٠٨ % | OrbiMed Advisors, LLC | ٤٨٥٬٠٠٠ | ٤٨٥٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٨ % | Qube Research & Technologies Ltd | ٤٦٦٬٦٧٤ | ٤٦٦٬٦٧٤ | ٣١/١٢/٢٠٢٣ |
٠٫٠٨ % | Northern Trust Global Investments | ٤٥٢٬٧٦٥ | -٤١٦٬٥٣١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | HRT Financial LP | ٤٣٧٬٠٢٧ | ٤٣٧٬٠٢٧ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | California State Teachers Retirement System | ٤٣٣٬٨٩٠ | -٨٠٬٦٦٧ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | JPMorgan Private Bank (United States) | ٤٣٢٬٥٧٠ | ٣٣٥٬٧٦٧ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | Legal & General Investment Management Ltd. | ٤١٠٬٤٢٢ | ٣١٨ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | Mellon Investments Corporation | ٤١٠٬٠٧١ | ٦٣٬٧٩٥ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | BlackRock Investment Management (UK) Ltd. | ٤٠٦٬٠٦٠ | -٥٢٬٦٠٣ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | Squarepoint Capital LLP | ٣٩٢٬١٩٧ | ١٤٩٬٥٣١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | Goldman Sachs Asset Management, L.P. | ٣٨٧٬٨٢٠ | -١٤٬٣٤٩ | ٣١/١٢/٢٠٢٣ |
٠٫٠٦ % | Fubon Asset Management Company Ltd. | ٣٧٥٬٥١٤ | -١١٬٧٨١ | ٢٩/٢/٢٠٢٤ |
٠٫٠٦ % | Assenagon Asset Management S.A. | ٣٧٣٬٨١٠ | ٢٧٬٠٣٠ | ٢٩/٢/٢٠٢٤ |
٠٫٠٦ % | State of Wisconsin Investment Board | ٣٧٢٬٦٤٣ | -١٨٬٦٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٦ % | Summit Wealth Strategies | ٣٦١٬٩٦١ | ٣٬٥٠٣ | ٣١/١٢/٢٠٢٣ |
٠٫٠٦ % | Alps Advisors, Inc. | ٣٥٨٬٧٨٢ | -٢٧٬٥١٨ | ٣١/١٢/٢٠٢٣ |
٠٫٠٦ % | Private Advisor Group LLC | ٣٥١٬١٤٤ | ٣٬٥٥٨ | ٣١/١٢/٢٠٢٣ |
٠٫٠٦ % | Allspring Global Investments, LLC | ٣٤٤٬٠٦٠ | -٦٬٩٦٢ | ٣١/٣/٢٠٢٤ |
٠٫٠٥ % | Polen Capital Management, LLC | ٣٢٥٬٨٨٠ | -١٧٢٬٦٨٥ | ٢٩/٢/٢٠٢٤ |
٠٫٠٥ % | Ostrum Asset Management | ٣١١٬٥٠٠ | ٣١١٬٥٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥ % | ProFund Advisors LLC | ٢٧٥٬٨٢٣ | -٤٧٬٠٣٤ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | MetLife Investment Management, LLC | ٢٦٢٬٦٦٢ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | Manulife Investment Management (North America) Limited | ٢٦٠٬٨٢٧ | ١٬٣٠١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | Two Sigma Investments, LP | ٢٥٥٬٠١٩ | ٢٥٥٬٠١٩ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | SunAmerica Asset Management, LLC | ٢٥٤٬٦٦٣ | ٦٬١٢٣ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | XTX Markets LLC | ٢٥٣٬٧٩٦ | ١٩٧٬٩٥٢ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | Kentucky Teachers' Retirement System | ٢٤٦٬٥٦٠ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | HighVista Strategies LLC | ٢٤٠٬٢٣٤ | ٣٩٬٣٤١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | Northern Trust Global Investments Limited | ٢٣٥٬٥٩٤ | -٦٤٬٧٣٩ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | UBS Asset Management (Switzerland) | ٢٣١٬١٠٦ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | Commonwealth Financial Network | ٢٣٠٬٢٦٤ | ١١٬٩٦٧ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | Osaic Holdings, Inc. | ٢٢٧٬٢٠٦ | -٧١٬٩٦٩ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | Cambridge Investment Research Advisors, Inc. | ٢٢٥٬٣٧٣ | -٣٦٬١٢٢ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | DWS Investments UK Limited | ٢٢٢٬٩٢٢ | -٥٬٨٩٢ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤ % | New York State Common Retirement Fund | ٢١٠٬٨٩٠ | ٢٥٬٩٥٩ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣ % | Voya Investment Management LLC | ٢٠٤٬١٢٥ | ٣٬٨٨١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣ % | Rosalind Advisors, Inc. | ٢٠٠٬٠٠٠ | ٢٠٠٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣ % | SG Americas Securities, L.L.C. | ١٩٢٬٤٤٥ | ١٧٣٬٣٧٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣ % | Invesco Advisers, Inc. | ١٨٨٬٧٨٤ | -١٣٬٣٦٧ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣ % | T. Rowe Price International Ltd | ١٨٧٬٧٧٩ | ١٦٬٥٠١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣ % | Jefferies LLC | ١٨٣٬٣٩١ | -٧١٬١٠٩ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣ % | Inspire Investing | ١٨١٬٣٦٩ | ٣٥٬٥٨٤ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣ % | Janus Henderson Investors | ١٨١٬٠١٨ | -٢٩٢ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣ % | BlackRock Asset Management Canada Limited | ١٧١٬٧٦٩ | ٤١٬٧٤٦ | ٣١/١٢/٢٠٢٣ |