٨٫٩٨ % | Avoro Capital Advisors LLC | ٢٬٥٦٥٬٥٥٥ | 0 | ٣١/١٢/٢٠٢٣ |
٨٫٥٢ % | The Vanguard Group, Inc. | ٢٬٤٣٢٬٠٣٨ | ٣٥٬٦٣٢ | ٣١/١٢/٢٠٢٣ |
٨٫٣٤ % | Fidelity Management & Research Company LLC | ٢٬٣٨١٬٢٠٥ | -٨٢٬١٦٦ | ٣١/١٢/٢٠٢٣ |
٦٫١٤ % | Krishnan (Krish S) | ١٬٧٥٢٬٢٦٢ | -٢٥٬٠٠٠ | ٢٥/٣/٢٠٢٤ |
٦٫٠٧ % | Redmile Group, LLC | ١٬٧٣٣٬١٨٩ | -٢٧٠٬١٧٨ | ٣١/١٢/٢٠٢٣ |
٥٫٧٥ % | Krishnan (Suma M) | ١٬٦٤٠٬٨٨٢ | -٢٥٬٠٠٠ | ٢٥/٣/٢٠٢٤ |
٥٫٧٤ % | BlackRock Institutional Trust Company, N.A. | ١٬٦٣٩٬٢٨٠ | ١٢٠٬٤٠٩ | ٣١/١٢/٢٠٢٣ |
٤٫٣٣ % | State Street Global Advisors (US) | ١٬٢٣٧٬٤٩٧ | ٢٠٥٬٦٧٠ | ٣١/١٢/٢٠٢٣ |
٣٫٤٦ % | Frazier Healthcare Partners | ٩٨٨٬٤٦٠ | 0 | ٣١/١٢/٢٠٢٣ |
٢٫٥٤ % | Jennison Associates LLC | ٧٢٤٬٣٤٤ | ٣٨٣٬٤٩٥ | ٣١/١٢/٢٠٢٣ |
٢٫١٧ % | Lord, Abbett & Co. LLC | ٦١٨٬٤٥٨ | -٥٢٬٨٥٣ | ٣١/١٢/٢٠٢٣ |
١٫٩٣ % | Dimensional Fund Advisors, L.P. | ٥٥٠٬٨٠٦ | ٣٠٬١٦٩ | ٣١/١٢/٢٠٢٣ |
١٫٧٩ % | Geode Capital Management, L.L.C. | ٥١١٬٢٤٦ | ٢٨٬٠١١ | ٣١/١٢/٢٠٢٣ |
١٫٦٩ % | Woodline Partners LP | ٤٨١٬٩٧٩ | ١٦٠٬٠٣٥ | ٣١/١٢/٢٠٢٣ |
١٫٦٦ % | Credit Suisse Funds AG | ٤٧٤٬٤٨٤ | ٢٤١٬٣٦١ | ٣١/١٢/٢٠٢٣ |
١٫٦١ % | Hood River Capital Management LLC | ٤٥٨٬٥١٣ | -١٬٩٧٦ | ٣١/١٢/٢٠٢٣ |
١٫٤٥ % | T. Rowe Price Associates, Inc. | ٤١٣٬٨١٣ | ١٦٩٬٦١٦ | ٣١/١٢/٢٠٢٣ |
٠٫٩٦ % | Morgan Stanley & Co. LLC | ٢٧٥٬١٢٤ | ٣٦٬٤٥٢ | ٣١/١٢/٢٠٢٣ |
٠٫٩٣ % | Medical Strategy GmbH | ٢٦٥٬٧٩٨ | ٢٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٩٠ % | Balyasny Asset Management LP | ٢٥٦٬٦٠٤ | ٢٢٣٬٩٦٢ | ٣١/١٢/٢٠٢٣ |
٠٫٨٨ % | TimesSquare Capital Management, LLC | ٢٥٠٬٤٧٠ | ١٢٧٬٤٣٥ | ٣١/١٢/٢٠٢٣ |
٠٫٨٥ % | SEB Investment Management AB | ٢٤٤٬٠٦١ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٨٥ % | Nuveen LLC | ٢٤٣٬٧٣٣ | ١٠٬٠٨٠ | ٣١/١٢/٢٠٢٣ |
٠٫٨٥ % | First Turn Management, LLC | ٢٤٢٬١٨٥ | ٢٤٢٬١٨٥ | ٣١/١٢/٢٠٢٣ |
٠٫٦٩ % | Driehaus Capital Management, LLC | ١٩٦٬٣٨٦ | -٢٬٢٩٧ | ٣١/١٢/٢٠٢٣ |
٠٫٦٩ % | Braidwell LP | ١٩٦٬٢٠٠ | ١١٨٬٧٠٣ | ٣١/١٢/٢٠٢٣ |
٠٫٦٨ % | Pictet Asset Management Ltd. | ١٩٢٬٨٧٥ | -١٨٠٬٩٣٧ | ٣١/١٢/٢٠٢٣ |
٠٫٦٧ % | Northern Trust Investments, Inc. | ١٩١٬٥٦٠ | ٥٬٤٤٠ | ٣١/١٢/٢٠٢٣ |
٠٫٦٥ % | C WorldWide Asset Management Fondsmaeglerselskab A/S | ١٨٥٬٨٠٩ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٦٥ % | Charles Schwab Investment Management, Inc. | ١٨٥٬٠٣٨ | ٥٬٢٥٨ | ٣١/١٢/٢٠٢٣ |
٠٫٦٣ % | JPMorgan Asset Management U.K. Limited | ١٧٩٬٤٤٤ | -٨٬٧٣٤ | ٣١/١٢/٢٠٢٣ |
٠٫٦١ % | Victory Capital Management Inc. | ١٧٢٬٨٧٩ | -٣٦٬٦٠٨ | ٣١/١٢/٢٠٢٣ |
٠٫٦٠ % | Fidelity Investments Canada ULC | ١٧٠٬٤٥٩ | -٤٬٠٦٦ | ٣١/١٢/٢٠٢٣ |
٠٫٦٠ % | Baker Bros. Advisors LP | ١٦٩٬٩٣٤ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٥٦ % | Fred Alger Management, LLC | ١٦٠٬٣٣٥ | -٧٬١٥٠ | ٣١/١٢/٢٠٢٣ |
٠٫٥٥ % | Allspring Global Investments, LLC | ١٥٨٬٤٢٥ | ٩٩٬١٠١ | ٣١/٣/٢٠٢٤ |
٠٫٤٨ % | Goldman Sachs & Company, Inc. | ١٣٧٬٢٦٥ | ٣٢٬٠١١ | ٣١/١٢/٢٠٢٣ |
٠٫٤٨ % | Eventide Asset Management, LLC | ١٣٦٬٤٨٥ | ١٣٦٬٤٨٥ | ٣١/١٢/٢٠٢٣ |
٠٫٤٣ % | Handelsbanken Kapitalförvaltning AB | ١٢٣٬٢٠٠ | ١٠٬٤٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٣٩ % | S Squared Technology, LLC | ١١٠٬٢١٥ | ٢٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٣٨ % | Janney (Daniel Spencer) | ١٠٧٬٣٦٢ | -١٢٥٬٠٠٠ | ٢٥/٣/٢٠٢٤ |
٠٫٣٦ % | Rock Springs Capital Management LP | ١٠٣٬٩٦٩ | ١٣٬٤٠٩ | ٣١/١٢/٢٠٢٣ |
٠٫٣٦ % | OrbiMed Advisors, LLC | ١٠٣٬٧٠٠ | ١٠٣٬٧٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٣٤ % | Capital Research Global Investors | ٩٧٬١٤٧ | ٩٧٬١٤٧ | ٣١/٣/٢٠٢٤ |
٠٫٣٤ % | Verition Fund Management LLC | ٩٥٬٩٥٨ | -٣١٬١١٢ | ٣١/١٢/٢٠٢٣ |
٠٫٣٢ % | Goldman Sachs Asset Management, L.P. | ٩٠٬٧٨٨ | ١١٬٦٩٨ | ٣١/١٢/٢٠٢٣ |
٠٫٣٠ % | Integral Health Asset Management, LLC | ٨٥٬٠٠٠ | ١٥٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٢٩ % | Rafferty Asset Management LLC | ٨٤٬٠٢١ | ١٢٬٢١٥ | ٣١/١٢/٢٠٢٣ |
٠٫٢٩ % | Rossi (Dino A) | ٨٣٬٦٩١ | 0 | ٢٥/٣/٢٠٢٤ |
٠٫٢٨ % | BofA Global Research (US) | ٨١٬٢٣٣ | ١٨٬٠٠٨ | ٣١/١٢/٢٠٢٣ |
٠٫٢٨ % | Eversept Partners, LP | ٨٠٬٧٩٨ | -٢٧٬٩٧٣ | ٣١/١٢/٢٠٢٣ |
٠٫٢٦ % | Schroder Investment Management Ltd. (SIM) | ٧٤٬٩٤٥ | ٧٤٬٩٤٥ | ٣١/١٢/٢٠٢٣ |
٠٫٢٥ % | Nuveen Asset Management, LLC | ٧١٬٧٣٢ | ٤٣٬١٥١ | ٣١/١٢/٢٠٢٣ |
٠٫٢٥ % | Marshall Wace LLP | ٧٠٬٩٠١ | ٦١٬٣٧٣ | ٣١/١٢/٢٠٢٣ |
٠٫٢٤ % | D. E. Shaw & Co., L.P. | ٦٧٬١٤١ | ١١٬٣٨٤ | ٣١/١٢/٢٠٢٣ |
٠٫٢٣ % | Decheng Capital LLC | ٦٥٬٧٧٢ | ٦٥٬٧٧٢ | ٣١/١٢/٢٠٢٣ |
٠٫٢٢ % | Barclays Bank PLC | ٦٤٬٠٦٢ | ٢٤٬٥٤٢ | ٣١/١٢/٢٠٢٣ |
٠٫٢٢ % | Wellington Management Company, LLP | ٦٣٬٧٩٩ | -٩٦ | ٢٩/٢/٢٠٢٤ |
٠٫٢٢ % | BlackRock Financial Management, Inc. | ٦١٬٩٨٦ | -٣٬١٦٧ | ٣١/١٢/٢٠٢٣ |
٠٫٢١ % | BNY Mellon Asset Management | ٦٠٬٤١٩ | ٨٧١ | ٣١/١٢/٢٠٢٣ |
٠٫٢٠ % | ACT Capital Management, L.L.C. | ٥٨٬٣٠٠ | -٧٠٠ | ٣٠/٩/٢٠٢٢ |
٠٫١٩ % | Candriam Luxembourg S.A. | ٥٥٬٠٠٠ | 0 | ٢٩/٢/٢٠٢٤ |
٠٫١٩ % | Candriam Belgium S.A. | ٥٥٬٠٠٠ | -١٥٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٩ % | BlackRock Investment Management, LLC | ٥٤٬٣٠٨ | ٣٩٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٩ % | Monarch Partners Asset Management LLC | ٥٣٬٩٠٥ | ٧٬٤١١ | ٣١/١٢/٢٠٢٢ |
٠٫١٨ % | AHL Partners LLP | ٥٠٬٨٣٦ | ٥٠٬٨٣٦ | ٣١/١٢/٢٠٢٣ |
٠٫١٨ % | Jane Street Capital, L.L.C. | ٥٠٬٦١٨ | -٢٤٬٥٠٨ | ٣١/١٢/٢٠٢٣ |
٠٫١٨ % | Ghost Tree Capital, LLC | ٥٠٬٠٠٠ | -٣٠٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٧ % | Nicholas Investment Partners, L.P. | ٤٩٬٠٧٣ | -٣٠٦٬٥٣٨ | ٣١/١٢/٢٠٢٣ |
٠٫١٦ % | International Biotechnology Trust PLC | ٤٦٬٠٩٢ | ١٤٧ | ٣٠/٩/٢٠٢٣ |
٠٫١٦ % | Voya Investment Management LLC | ٤٥٬٨٥٣ | ١٧٬٤١٣ | ٣١/١٢/٢٠٢٣ |
٠٫١٦ % | Invesco Advisers, Inc. | ٤٤٬٥٤٤ | ٣٣٬٧٢٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٥ % | ExodusPoint Capital Management, LP | ٤٢٬٥٠٢ | ١٤٬٧٥٢ | ٣١/١٢/٢٠٢٣ |
٠٫١٥ % | Arctic Fund Management AS | ٤٢٬١٥٤ | ٨٬١٨٠ | ٢٩/٢/٢٠٢٤ |
٠٫١٤ % | TD Asset Management Inc. | ٤٠٬٩٦٢ | ١٨٬٥٤٢ | ٣١/١٢/٢٠٢٣ |
٠٫١٤ % | Soleus Capital Management, L.P. | ٤٠٬٠٠٠ | -٧٧٬٨٩٢ | ٣١/١٢/٢٠٢٣ |
٠٫١٤ % | Putnam Investment Management, L.L.C. | ٣٩٬٣٢٢ | ٤٬٥٢٩ | ٣١/١٢/٢٠٢٣ |
٠٫١٤ % | BNP Paribas Securities Corp. North America | ٣٩٬٠٧٢ | ١٠٬٠٥٧ | ٣١/١٢/٢٠٢٣ |
٠٫١٣ % | PGIM Securities Investment Trust Enterprise | ٣٧٬٨٠٠ | -٢٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٣ % | Citi Investment Research (US) | ٣٦٬٥٦٦ | ٧٧٩ | ٣١/١٢/٢٠٢٣ |
٠٫١٣ % | Mutual of America Capital Management LLC | ٣٦٬٣٨٨ | -١٬١٥١ | ٣١/١٢/٢٠٢٣ |
٠٫١٣ % | Schweizerische Nationalbank | ٣٥٬٩٠٠ | -٣٬٥٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٢ % | Mellon Investments Corporation | ٣٥٬٢٨٧ | ٢٬٨٧٣ | ٣١/١٢/٢٠٢٣ |
٠٫١٢ % | Hennion & Walsh Asset Management, Inc. | ٣٣٬١٥٤ | ١٬٧٥٦ | ٣١/٣/٢٠٢٤ |
٠٫١١ % | BlackRock Advisors (UK) Limited | ٣٢٬٦١٦ | ١٬٢٢٤ | ٣١/٣/٢٠٢٤ |
٠٫١١ % | CastleArk Management, LLC | ٣٢٬٣٥٠ | ٢٠٬٩٣٠ | ٣١/١٢/٢٠٢٣ |
٠٫١١ % | Rhumbline Advisers Ltd. Partnership | ٣١٬٧٨٥ | -٦١٨ | ٣١/١٢/٢٠٢٣ |
٠٫١١ % | Parametric Portfolio Associates LLC | ٣١٬٢٣٢ | -٨٬١١٣ | ٣١/١٢/٢٠٢٣ |
٠٫١١ % | UBS Financial Services, Inc. | ٣٠٬٧٦٠ | ٣٠٬٧٦٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٠ % | Kennedy Capital Management LLC | ٢٩٬٦٧٣ | ٢٩٬٦٧٣ | ٣١/١٢/٢٠٢٣ |
٠٫١٠ % | Manulife Investment Management (North America) Limited | ٢٩٬٢٥٠ | ٨٬٨١٣ | ٣١/١٢/٢٠٢٣ |
٠٫١٠ % | BlackRock Asset Management Ireland Limited | ٢٧٬٥٩٢ | -٣٬٩٤٤ | ٣١/١٢/٢٠٢٣ |
٠٫٠٩ % | AllianceBernstein L.P. | ٢٥٬٩٠٠ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٠٩ % | Schonfeld Strategic Advisors LLC | ٢٥٬٥٦٦ | -٥٨٬٠٦٩ | ٣١/١٢/٢٠٢٣ |
٠٫٠٩ % | Affinity Asset Advisors LLC | ٢٥٬٠٠٠ | -٣٢٬٥٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٩ % | Franklin Advisers, Inc. | ٢٤٬٨٦٦ | ٣٧٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٩ % | New Jersey Division of Investment | ٢٤٬٨٠٤ | ٤٬٤٧٥ | ٣١/١٢/٢٠٢٣ |
٠٫٠٨ % | Carson Wealth Management Group | ٢٣٬٨٥٠ | -٦٬٧١٩ | ٣١/٣/٢٠٢٤ |
٠٫٠٨ % | Scout Investments, Inc. | ٢٣٬٦١١ | ٢٣٬٦١١ | ٢٩/٢/٢٠٢٤ |
٠٫٠٨ % | GW&K Investment Management, LLC | ٢٣٬٦٠٠ | ٢٣٬٦٠٠ | ٣١/١/٢٠٢٤ |