٦٫٨٩ % | Fred Alger Management, LLC | ٣٬٣٢٧٬١٣٢ | -٩٣٢٬٣٢٣ | ٣١/١٢/٢٠٢٣ |
٦٫٧٧ % | Adage Capital Management, L.P. | ٣٬٢٦٦٬٦٤٥ | 0 | ٣١/١٢/٢٠٢٣ |
٥٫٥٣ % | BlackRock Institutional Trust Company, N.A. | ٢٬٦٧١٬٣١٦ | ٥٠٤٬١٢١ | ٣١/١٢/٢٠٢٣ |
٥٫٣٧ % | State Street Global Advisors (US) | ٢٬٥٩٤٬٤٧٠ | ١٬٠٦١٬٦٢٨ | ٣١/١٢/٢٠٢٣ |
٥٫٣١ % | VR Adviser, LLC | ٢٬٥٦٣٬٩٥٢ | ٥٩٠٬٦٩٩ | ٣١/١٢/٢٠٢٣ |
٤٫٤٠ % | The Vanguard Group, Inc. | ٢٬١٢٦٬١٢٤ | ١٦٣٬٨٢٣ | ٣١/١٢/٢٠٢٣ |
٤٫٣٧ % | Lynx1 Capital Advisors LLC | ٢٬١١٠٬٤٠١ | ٤٬٤٠١ | ٣١/١٢/٢٠٢٣ |
٤٫١٦ % | Deerfield Management Company, L.P. | ٢٬٠٠٧٬٧٢٩ | -٣٣٢٬٣٨٩ | ٣١/١٢/٢٠٢٣ |
٤٫١٥ % | Perceptive Advisors LLC | ٢٬٠٠٣٬٠٥٨ | ٨٧٠٬٥٦٧ | ٣١/١٢/٢٠٢٣ |
٤٫١٤ % | Bain Capital Life Sciences Investors, LLC | ٢٬٠٠٠٬٠٠٠ | 0 | ٣١/١٢/٢٠٢٣ |
٣٫٩٨ % | Holocene Advisors, LP | ١٬٩٢٠٬٣٢٣ | ٧٣٧٬٢٧٧ | ٣١/١٢/٢٠٢٣ |
٣٫٩٤ % | Commodore Capital LP | ١٬٩٠٠٬٠٠٠ | -٦٢٥٬٧٥٣ | ٣١/١٢/٢٠٢٣ |
٣٫٨٠ % | T. Rowe Price Investment Management, Inc. | ١٬٨٣٢٬٨٥٤ | ١٬٨٣٢٬٨٥٤ | ٣١/١٢/٢٠٢٣ |
٣٫٣٧ % | Jennison Associates LLC | ١٬٦٢٦٬٦٢٨ | ٢٠٤٬٢٦١ | ٣١/١٢/٢٠٢٣ |
٢٫٨٥ % | Redmile Group, LLC | ١٬٣٧٤٬١٨٩ | -٤٠٠٬٠٦٣ | ٣١/١٢/٢٠٢٣ |
٢٫٨٠ % | Nichtberger (Steven) | ١٬٣٤٩٬٤٨٣ | 0 | ٣١/١٢/٢٠٢٣ |
٢٫٥٩ % | Polar Capital LLP | ١٬٢٥٠٬٠٠٠ | ١٬٢٥٠٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٢٫٣٢ % | BlackRock Financial Management, Inc. | ١٬١٢١٬٧٠٠ | ٩٤٧٬٤٨٣ | ٣١/١٢/٢٠٢٣ |
١٫٥٦ % | Geode Capital Management, L.L.C. | ٧٥٣٬١٧٦ | ٦١٬٣٠٤ | ٣١/١٢/٢٠٢٣ |
١٫٤٧ % | Invesco Capital Management LLC | ٧٠٩٬٢٩٧ | -١٣٠٬٣٢٨ | ٣١/١٢/٢٠٢٣ |
١٫٣٩ % | Invesco Advisers, Inc. | ٦٧٠٬٦٢٩ | ٦٥٦٬٢١١ | ٣١/١٢/٢٠٢٣ |
١٫١٢ % | Wellington Management Company, LLP | ٥٣٩٬٨٧٦ | ٢٩٣٬٣٠٦ | ٣١/١٢/٢٠٢٣ |
١٫٠٨ % | Integral Health Asset Management, LLC | ٥٢٠٬٠٠٠ | ١٩٠٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
١٫٠٦ % | T. Rowe Price Associates, Inc. | ٥١١٬٩٧٩ | ٥٠٢٬٧٢٢ | ٣١/١٢/٢٠٢٣ |
١٫٠١ % | TCG Crossover Management, LLC | ٤٨٦٬٧٩٥ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٩٣ % | StemPoint Capital LP | ٤٥٠٬٧٠٦ | ٤٥٠٬٧٠٦ | ٣١/١٢/٢٠٢٣ |
٠٫٨٩ % | Sofinnova Investments, Inc | ٤٢٩٬٣٩٥ | ٤٢٩٬٣٩٥ | ٣١/١٢/٢٠٢٣ |
٠٫٨٧ % | BlackRock Investment Management (UK) Ltd. | ٤٢٠٬٦٢٠ | ٤١٨٬٩٢٠ | ٣١/١٢/٢٠٢٣ |
٠٫٨٤ % | Victory Capital Management Inc. | ٤٠٣٬٩٢٧ | ٣٣٧٬٢٧٧ | ٣١/١٢/٢٠٢٣ |
٠٫٧٢ % | Blackstone Alternative Asset Management, L.P. | ٣٤٧٬٤٩٤ | ٣٤٧٬٤٩٤ | ٣١/١٢/٢٠٢٣ |
٠٫٦٢ % | Alkeon Capital Management LLC | ٢٩٩٬٩٥٥ | ٢٩٩٬٩٥٥ | ٣١/١٢/٢٠٢٣ |
٠٫٦٠ % | Northern Trust Investments, Inc. | ٢٨٨٬٥١٣ | ١٥٬٥٠٦ | ٣١/١٢/٢٠٢٣ |
٠٫٥٩ % | Point72 Asset Management, L.P. | ٢٨٤٬٦٦٦ | ٢٨٤٬٦٦٦ | ٣١/١٢/٢٠٢٣ |
٠٫٥٢ % | Schonfeld Strategic Advisors LLC | ٢٥١٬٦١٥ | ٢٥١٬٦١٥ | ٣١/١٢/٢٠٢٣ |
٠٫٥١ % | Morgan Stanley & Co. LLC | ٢٤٥٬٧٨٧ | ١٦٩٬٤٦٠ | ٣١/١٢/٢٠٢٣ |
٠٫٥٠ % | Woodline Partners LP | ٢٤١٬٤٥٣ | ١٠٧٬٢٦٩ | ٣١/١٢/٢٠٢٣ |
٠٫٥٠ % | Nuveen LLC | ٢٣٩٬٩٧٧ | ١٠٣٬٩٩٩ | ٣١/١٢/٢٠٢٣ |
٠٫٤٩ % | Voloridge Investment Management, LLC | ٢٣٦٬٤٠٠ | ٢٢٥٬٦٣٨ | ٣١/١٢/٢٠٢٣ |
٠٫٤٨ % | Cutter Capital Management, LP | ٢٣٠٬٠٠٠ | ٢٣٠٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٤٥ % | Ikarian Capital LLC | ٢١٦٬٦٢٠ | ٢١٦٬٦٢٠ | ٣١/١٢/٢٠٢٣ |
٠٫٤٣ % | Rafferty Asset Management LLC | ٢٠٩٬٢٦٣ | ٩١٬١١٣ | ٣١/١٢/٢٠٢٣ |
٠٫٤٢ % | Goldman Sachs & Company, Inc. | ٢٠٤٬٦٣٢ | -٦٥٬٠٥٣ | ٣١/١٢/٢٠٢٣ |
٠٫٤١ % | Candriam Luxembourg S.A. | ٢٠٠٬٠٠٠ | ٢٠٠٬٠٠٠ | ٢٩/٢/٢٠٢٤ |
٠٫٣٦ % | First Turn Management, LLC | ١٧٥٬٣٥٩ | ١٧٥٬٣٥٩ | ٣١/١٢/٢٠٢٣ |
٠٫٣٣ % | BofA Global Research (US) | ١٦٠٬٥٢٠ | ١٩٬٣٣٤ | ٣١/١٢/٢٠٢٣ |
٠٫٣١ % | Norges Bank Investment Management (NBIM) | ١٥١٬٩٤٤ | ١٥١٬٩٤٤ | ٣١/١٢/٢٠٢٣ |
٠٫٣١ % | Ghost Tree Capital, LLC | ١٥٠٬٠٠٠ | ١٥٠٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٣٠ % | Simon (Mark) | ١٤٣٬١٤٤ | ٧٬٠٠٠ | ٣/٤/٢٠٢٣ |
٠٫٢٩ % | UBS Financial Services, Inc. | ١٣٨٬٦٤٥ | ١٠٣٬٦٦٢ | ٣١/١٢/٢٠٢٣ |
٠٫٢٧ % | Barclays Bank PLC | ١٢٩٬٠٧٢ | ٦٤٬٤٨٦ | ٣١/١٢/٢٠٢٣ |
٠٫٢٦ % | Morgan Stanley Smith Barney LLC | ١٢٤٬٦٢٠ | -٢٠٬١٩٤ | ٣١/١٢/٢٠٢٣ |
٠٫٢٤ % | Ensign Peak Advisors, Inc. | ١١٨٬٠٠٢ | ١١٨٬٠٠٢ | ٣١/١٢/٢٠٢٣ |
٠٫٢٣ % | BlackRock Investment Management, LLC | ١٠٩٬٥٠٥ | ٢٨٬٩٣٤ | ٣١/١٢/٢٠٢٣ |
٠٫٢٠ % | BNY Mellon Asset Management | ٩٧٬٥٥٨ | ٢٬٩٩٦ | ٣١/١٢/٢٠٢٣ |
٠٫٢٠ % | Charles Schwab Investment Management, Inc. | ٩٦٬٣١٠ | ٣٠٥ | ٣١/١٢/٢٠٢٣ |
٠٫١٩ % | TD Asset Management Inc. | ٩٣٬٦٣٠ | ٩٣٬٦٣٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٩ % | AllianceBernstein L.P. | ٩٣٬٣٣٢ | -٧٢٬٠٧١ | ٣١/١٢/٢٠٢٣ |
٠٫١٨ % | Jane Street Capital, L.L.C. | ٨٨٬٤٠٩ | ٨٨٬٤٠٩ | ٣١/١٢/٢٠٢٣ |
٠٫١٨ % | RBC Capital Markets Wealth Management | ٨٦٬٨١٦ | -١٣٬١١٥ | ٣١/١٢/٢٠٢٣ |
٠٫١٨ % | Citi Investment Research (US) | ٨٦٬٥٤٦ | ٣٦٬٨٥١ | ٣١/١٢/٢٠٢٣ |
٠٫١٧ % | BlackRock Advisors (UK) Limited | ٨٢٬٣٧٥ | ٢٬٥٥٣ | ٣١/٣/٢٠٢٤ |
٠٫١٧ % | Rokos Capital Management LLP | ٨٠٬٣٣٥ | -٩٣٬٥١٥ | ٣١/١٢/٢٠٢٣ |
٠٫١٦ % | Weatherbie Capital, LLC | ٧٧٬١٥٣ | ٥٢٬٧٤٥ | ٢٩/٢/٢٠٢٤ |
٠٫١٥ % | Two Sigma Investments, LP | ٧٤٬٧٩١ | ٢٨٬٠٦٦ | ٣١/١٢/٢٠٢٣ |
٠٫١٤ % | BlackRock Asset Management Ireland Limited | ٦٩٬١١٤ | ٥٠٬٩٢٤ | ٣١/١٢/٢٠٢٣ |
٠٫١٤ % | Neuberger Berman, LLC | ٦٨٬٣٢٩ | ٦٨٬٣٢٩ | ٢٩/٢/٢٠٢٤ |
٠٫١٤ % | PGIM Securities Investment Trust Enterprise | ٦٧٬٠٠٠ | -١١٨٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٢ % | Oppenheimer Asset Management Inc. | ٦٠٬٠٤٥ | ٦٠٬٠٤٥ | ٣١/١٢/٢٠٢٣ |
٠٫١٢ % | Boothbay Fund Management, LLC | ٥٨٬٧٥٥ | ٥٨٬٧٥٥ | ٣١/١٢/٢٠٢٣ |
٠٫١١ % | Nicholas Investment Partners, L.P. | ٥٤٬٥٨٦ | ٤١٬٤٠٨ | ٣١/١٢/٢٠٢٣ |
٠٫١١ % | Manulife Investment Management (North America) Limited | ٥٢٬٦٧٧ | ٣٩٬٤٢٧ | ٣١/١٢/٢٠٢٣ |
٠٫١١ % | Qube Research & Technologies Ltd | ٥٢٬١٩٩ | ٥٢٬١٩٩ | ٣١/١٢/٢٠٢٣ |
٠٫١١ % | Schweizerische Nationalbank | ٥١٬٠٠٠ | -١٠٬١٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٠ % | Marda (Anup) | ٥٠٬٠٠٠ | ٥٠٬٠٠٠ | ١٨/١٠/٢٠٢٢ |
٠٫١٠ % | Nan Fung Life Sciences | ٤٧٬١٥٠ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫١٠ % | Exome Asset Management LLC | ٤٦٬٧٠٠ | ٤٦٬٧٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٠ % | Churchill Management Group | ٤٦٬٦٠٦ | -٢٬٧٥٠ | ٣١/٣/٢٠٢٤ |
٠٫١٠ % | Bridgeway Capital Management, LLC | ٤٦٬٠٢١ | -٤٬٦٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٩ % | Rhumbline Advisers Ltd. Partnership | ٤٤٬١٤٧ | ١٬٥٤٥ | ٣١/١٢/٢٠٢٣ |
٠٫٠٩ % | MFS Investment Management | ٤٢٬٨٩٠ | -١٬٥٦٠ | ٢٩/٢/٢٠٢٤ |
٠٫٠٨ % | Newton Investment Management North America, LLC | ٣٩٬٩٠٠ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٠٨ % | Caption Management, LLC | ٣٨٬٣٠٠ | ٣٨٬٣٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٨ % | LPL Financial LLC | ٣٧٬٦٣٨ | -٢٢٣ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | SEB Investment Management AB | ٣٥٬٠٧٢ | -١٣٧ | ٢٩/٢/٢٠٢٤ |
٠٫٠٧ % | Citadel Advisors LLC | ٣٣٬٨٨٠ | ٣١٬٤١٧ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | ProFund Advisors LLC | ٣٣٬٨٥٨ | ١٣٬٧٣٧ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | Goldman Sachs Asset Management, L.P. | ٣٣٬٥٠٥ | ٣٬١٣٨ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | Credit Suisse Funds AG | ٣٣٬٣٨٨ | ١٣٬٣٦٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧ % | Envestnet Asset Management, Inc. | ٣٣٬٠٨١ | -٤٢٬٢٨٤ | ٣١/١٢/٢٠٢٣ |
٠٫٠٦ % | Assenagon Asset Management S.A. | ٢٩٬٣٤٦ | ٢٬١٢٧ | ٢٩/٢/٢٠٢٤ |
٠٫٠٦ % | Cubist Systematic Strategies, LLC | ٢٩٬٢٤١ | ٢٩٬٢٤١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٦ % | California State Teachers Retirement System | ٢٨٬٧١٧ | -٣٬٤٤٤ | ٣١/١٢/٢٠٢٣ |
٠٫٠٦ % | Osaic Holdings, Inc. | ٢٧٬٦٨٠ | -١٩٬٦٩٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥ % | Legal & General Investment Management Ltd. | ٢٥٬٦١١ | -٦٬٠٣٢ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥ % | Dimensional Fund Advisors, L.P. | ٢٥٬٣٧٥ | -٥٣٬٣٣٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥ % | New York State Common Retirement Fund | ٢٥٬١٩١ | ١٤٬٨٢٨ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥ % | Mirae Asset Global Investments (USA) LLC | ٢٣٬٦٨٩ | ٦٬٨٩١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥ % | Squarepoint Capital LLP | ٢٣٬٦٣٣ | ٤٬٣٤١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥ % | State of Wisconsin Investment Board | ٢٣٬٠٥٣ | -٥٬٦٥٦ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥ % | JPMorgan Private Bank (United States) | ٢٢٬٧٧٩ | ٢٢٬٧٧٩ | ٣١/١٢/٢٠٢٣ |