9,87555 % | SB Investment Advisers (UK) Limited | 73 031 667 | 0 | 31.12.2023 |
9,38027 % | Viking Global Investors LP | 69 368 961 | -4 065 340 | 31.12.2023 |
9,02204 % | QVT Financial LP | 66 719 779 | -45 821 757 | 07.03.2024 |
6,61638 % | Ramaswamy (Vivek) | 48 929 426 | -3 000 000 | 02.01.2024 |
4,99863 % | Fidelity Management & Research Company LLC | 36 965 882 | -1 917 081 | 31.12.2023 |
2,56923 % | Rubric Capital Management LP | 19 000 000 | 8 500 000 | 31.12.2023 |
2,50257 % | Morgan Stanley Investment Management Inc. (US) | 18 507 020 | 740 951 | 31.12.2023 |
2,42194 % | BlackRock Institutional Trust Company, N.A. | 17 910 694 | 1 628 124 | 31.12.2023 |
13,90759 % | Dexcel Pharma Technologies, Ltd. | 102 849 443 | 0 | 31.12.2023 |
1,85626 % | State Street Global Advisors (US) | 13 727 418 | 3 406 626 | 31.12.2023 |
1,84450 % | Wellington Management Company, LLP | 13 640 416 | -1 202 560 | 31.12.2023 |
1,70921 % | Patient Square Capital, LP | 12 639 920 | 0 | 31.12.2023 |
1,15051 % | Two Seas Capital LP | 8 508 223 | 592 991 | 31.12.2023 |
1,02675 % | Baker Bros. Advisors LP | 7 593 024 | -4 284 147 | 31.12.2023 |
1,01168 % | Venker (Eric) | 7 481 566 | -16 003 | 20.03.2024 |
0,99199 % | Farallon Capital Management, L.L.C. | 7 336 000 | 3 482 600 | 31.12.2023 |
0,94897 % | The Vanguard Group, Inc. | 7 017 800 | 1 465 238 | 31.12.2023 |
0,83186 % | Woodline Partners LP | 6 151 767 | -1 022 486 | 31.12.2023 |
0,74705 % | Geode Capital Management, L.L.C. | 5 524 576 | 306 396 | 31.12.2023 |
0,71799 % | Sukhatme (Mayukh) | 5 309 683 | 362 870 | 30.03.2024 |
0,71330 % | Adage Capital Management, L.P. | 5 275 000 | -925 000 | 31.12.2023 |
0,65348 % | Anchorage Capital Group, L.L.C. | 4 832 642 | 0 | 31.12.2023 |
0,62894 % | Avoro Capital Advisors LLC | 4 651 162 | 0 | 31.12.2023 |
0,49978 % | Norges Bank Investment Management (NBIM) | 3 695 967 | 3 695 967 | 31.12.2023 |
0,48243 % | T. Rowe Price Associates, Inc. | 3 567 650 | -5 311 | 31.12.2023 |
0,47081 % | Citadel Advisors LLC | 3 481 703 | 3 355 500 | 31.12.2023 |
0,44162 % | Morgan Stanley & Co. LLC | 3 265 853 | 1 887 196 | 31.12.2023 |
0,37084 % | BVF Partners L.P. | 2 742 409 | 0 | 31.12.2023 |
0,37043 % | First Trust Advisors L.P. | 2 739 438 | 2 227 192 | 31.12.2023 |
0,36729 % | Pictet Asset Management Ltd. | 2 716 218 | 600 513 | 31.12.2023 |
0,34531 % | Loomis, Sayles & Company, L.P. | 2 553 630 | 568 695 | 31.12.2023 |
0,33725 % | Octagon Capital Advisors LP | 2 494 000 | -1 873 000 | 31.12.2023 |
0,33265 % | Slate Path Capital LP | 2 460 000 | 2 460 000 | 31.12.2023 |
0,31727 % | Nuveen LLC | 2 346 246 | 964 123 | 31.12.2023 |
0,29331 % | StemPoint Capital LP | 2 169 116 | 2 169 116 | 31.12.2023 |
0,28869 % | Tejara Capital Ltd. | 2 134 895 | 1 776 323 | 31.12.2023 |
0,27356 % | Charles Schwab Investment Management, Inc. | 2 023 027 | 99 148 | 31.12.2023 |
0,25502 % | Laurion Capital Management LP | 1 885 901 | 850 454 | 31.12.2023 |
0,24051 % | BlackRock Financial Management, Inc. | 1 778 624 | 1 428 184 | 31.12.2023 |
0,21514 % | Whitefort Capital Management, LP | 1 591 000 | 1 591 000 | 31.12.2023 |
0,20960 % | BlackBarn Capital Partners LP | 1 550 000 | 1 550 000 | 31.12.2023 |
0,19665 % | RTW Investments L.P. | 1 454 273 | -98 444 | 31.12.2023 |
0,18438 % | First Turn Management, LLC | 1 363 504 | 1 363 504 | 31.12.2023 |
0,18201 % | Tyro Capital Management LLC | 1 345 981 | 1 345 981 | 31.12.2023 |
0,18199 % | SC China Holding Ltd | 1 345 839 | 0 | 31.12.2023 |
0,17512 % | Northern Trust Investments, Inc. | 1 295 041 | 108 250 | 31.12.2023 |
0,17304 % | Decheng Capital LLC | 1 279 700 | -180 000 | 31.12.2023 |
0,16992 % | Adar1 Capital Management LLC | 1 256 591 | 1 256 591 | 31.12.2023 |
0,16430 % | PFM Health Sciences, LP | 1 215 033 | 0 | 31.12.2023 |
0,15469 % | Eventide Asset Management, LLC | 1 143 938 | -546 362 | 31.12.2023 |
0,15239 % | abrdn Inc. | 1 126 987 | 1 126 987 | 31.12.2023 |
0,15138 % | Founders Fund | 1 119 489 | 0 | 31.12.2023 |
0,14999 % | Millennium Management LLC | 1 109 179 | -1 126 442 | 31.12.2023 |
0,14658 % | Lakewood Capital Management, LP | 1 084 000 | 1 084 000 | 31.12.2023 |
0,14379 % | Assenagon Asset Management S.A. | 1 063 392 | 703 830 | 31.12.2023 |
0,13522 % | Invus Public Equities Advisors, LLC | 1 000 000 | 0 | 31.12.2023 |
0,13522 % | Cutter Capital Management, LP | 1 000 000 | 1 000 000 | 31.12.2023 |
0,13276 % | Pictet Asset Management (Japan) Ltd. | 981 815 | 981 815 | 31.10.2023 |
0,13159 % | Rafferty Asset Management LLC | 973 134 | 195 136 | 31.12.2023 |
0,12670 % | SEB Investment Management AB | 936 974 | 0 | 31.12.2023 |
0,12156 % | Connor, Clark & Lunn Investment Management Ltd. | 898 966 | 120 001 | 31.12.2023 |
0,11889 % | Pertento Partners LLP | 879 214 | 879 214 | 31.12.2023 |
0,11683 % | Tekla Capital Management LLC_NLE | 863 981 | 863 981 | 30.09.2023 |
0,11492 % | Ensign Peak Advisors, Inc. | 849 850 | 0 | 31.12.2023 |
0,10935 % | Philosophy Capital Management LLC | 808 638 | 808 638 | 31.12.2023 |
0,10927 % | Altitude Crest Partners Inc | 808 061 | 808 061 | 31.12.2023 |
0,10415 % | UBS Asset Management (Switzerland) | 770 206 | -16 747 | 31.12.2023 |
0,10128 % | Gline (Matthew) | 749 016 | 163 643 | 30.03.2024 |
0,10043 % | Lo (Andrew W.) | 742 725 | 52 142 | 15.09.2022 |
0,10006 % | Atika Capital Management LLC | 739 980 | 194 980 | 31.12.2023 |
0,09679 % | Invesco Capital Management LLC | 715 776 | -464 513 | 31.12.2023 |
0,09177 % | Clough Capital Partners, LP | 678 660 | -44 140 | 31.12.2023 |
0,09047 % | Platinum Asset Management | 669 047 | 70 315 | 31.12.2023 |
0,08377 % | BNY Mellon Asset Management | 619 494 | 60 773 | 31.12.2023 |
0,08242 % | Mellon Investments Corporation | 609 525 | 29 327 | 31.12.2023 |
0,08113 % | Ghost Tree Capital, LLC | 600 000 | 536 000 | 31.12.2023 |
0,07927 % | BlackRock Asset Management Ireland Limited | 586 238 | -44 962 | 31.12.2023 |
0,07393 % | Schweizerische Nationalbank | 546 746 | 41 000 | 31.12.2023 |
0,07113 % | Ardsley Advisory Partners LP | 526 050 | 76 050 | 31.12.2023 |
0,07025 % | Morgan Stanley Investment Management Ltd. (UK) | 519 504 | 453 952 | 29.02.2024 |
0,06761 % | Velan Capital Investment Management LP | 500 000 | 500 000 | 31.12.2023 |
0,06761 % | Affinity Asset Advisors LLC | 500 000 | 350 000 | 31.12.2023 |
0,06681 % | TD Asset Management Inc. | 494 084 | -725 496 | 31.12.2023 |
0,06665 % | Voya Investment Management LLC | 492 912 | -509 | 31.12.2023 |
0,06543 % | Managed Account Advisors LLC | 483 867 | -20 841 | 31.12.2023 |
0,06383 % | Walleye Capital LLC | 472 003 | 472 003 | 31.12.2023 |
0,05908 % | HSBC Private Bank (Suisse) S.A. | 436 928 | 18 215 | 29.02.2024 |
0,05865 % | Point72 Asset Management, L.P. | 433 700 | -2 272 700 | 31.12.2023 |
0,05702 % | Rhumbline Advisers Ltd. Partnership | 421 641 | 14 290 | 31.12.2023 |
0,05333 % | Barclays Bank PLC | 394 370 | 24 320 | 31.12.2023 |
0,04975 % | Citi Investment Research (US) | 367 906 | 41 475 | 31.12.2023 |
0,04875 % | Balyasny Asset Management LP | 360 551 | 360 551 | 31.12.2023 |
0,04733 % | Deka Vermögensmanagement GmbH | 350 000 | 0 | 31.12.2023 |
0,04733 % | Monashee Investment Management, LLC | 350 000 | -200 000 | 31.12.2023 |
0,04640 % | Allianz Global Investors U.S. LLC_NLE | 343 125 | 159 740 | 30.09.2023 |
0,04640 % | Allianz Global Investors GmbH | 343 125 | 0 | 31.01.2024 |
0,04577 % | Schroder Investment Management Ltd. (SIM) | 338 497 | 0 | 31.12.2023 |
0,04573 % | Macquarie Investment Management | 338 181 | 0 | 29.02.2024 |
0,04479 % | Pier Capital, LLC | 331 267 | -3 736 | 31.12.2023 |
0,04410 % | Superstring Capital Management LP | 326 161 | 326 161 | 31.12.2023 |