5,70 % | Adage Capital Management, L.P. | 5 398 825 | 2 879 568 | 09.02.2023 |
5,09 % | BlackRock Institutional Trust Company, N.A. | 4 823 128 | 487 993 | 31.12.2022 |
4,35 % | The Vanguard Group, Inc. | 4 124 924 | 528 638 | 31.12.2022 |
2,71 % | Leon (Francisco) | 2 573 000 | 0 | 13.02.2023 |
2,71 % | Palmer (Ashleigh) | 2 570 050 | 0 | 13.02.2023 |
12,53 % | Sessa Capital | 11 879 023 | -3 000 000 | 18.01.2023 |
1,64 % | State Street Global Advisors (US) | 1 558 238 | 263 813 | 31.12.2022 |
1,39 % | Geode Capital Management, L.L.C. | 1 322 189 | 125 392 | 31.12.2022 |
1,21 % | D. E. Shaw & Co., L.P. | 1 143 300 | 1 038 757 | 31.12.2022 |
1,18 % | VR Adviser, LLC | 1 118 653 | 0 | 31.12.2022 |
0,95 % | BioImpact Capital LLC | 898 483 | 158 139 | 31.12.2022 |
0,88 % | Verition Fund Management LLC | 838 716 | -28 449 | 31.12.2022 |
0,70 % | Two Sigma Investments, LP | 665 730 | 506 008 | 31.12.2022 |
0,58 % | 683 Capital Management LLC | 550 000 | 550 000 | 31.12.2022 |
0,57 % | Northern Trust Investments, Inc. | 538 434 | 41 127 | 31.12.2022 |
0,54 % | Invesco Capital Management LLC | 512 298 | 509 787 | 31.12.2022 |
0,45 % | Millennium Management LLC | 423 295 | 423 295 | 31.12.2022 |
0,43 % | Nuveen LLC | 411 306 | 29 409 | 31.12.2022 |
0,42 % | Ghost Tree Capital, LLC | 400 000 | 400 000 | 31.12.2022 |
0,41 % | Palo Alto Investors LP | 390 800 | 0 | 31.12.2022 |
0,37 % | BlackRock Advisors (UK) Limited | 352 214 | 2 658 | 28.02.2023 |
0,35 % | Medical Strategy GmbH | 334 200 | 0 | 30.09.2022 |
0,35 % | BlackRock Asset Management Ireland Limited | 333 685 | 21 052 | 31.12.2022 |
0,34 % | Banque Lombard Odier & Cie SA | 322 895 | 322 895 | 31.12.2022 |
0,34 % | Lombard Odier Asset Management (Europe) Ltd | 322 792 | 147 734 | 31.12.2022 |
0,33 % | Voloridge Investment Management, LLC | 310 693 | 310 693 | 31.12.2022 |
0,32 % | Schonfeld Strategic Advisors LLC | 306 546 | 306 546 | 31.12.2022 |
0,30 % | Advisory Research, Inc. | 288 707 | 53 707 | 31.12.2022 |
0,29 % | EAM Investors, LLC | 276 250 | 276 250 | 31.12.2022 |
0,28 % | Jane Street Capital, L.L.C. | 261 657 | 250 153 | 31.12.2022 |
0,25 % | Principal Global Investors (Equity) | 239 073 | 223 922 | 31.12.2022 |
0,24 % | Cubist Systematic Strategies, LLC | 229 409 | 131 483 | 31.12.2022 |
0,22 % | EAM Global Investors LLC | 209 856 | 209 856 | 31.12.2022 |
0,21 % | Morgan Stanley & Co. LLC | 195 233 | -136 881 | 31.12.2022 |
0,21 % | BNY Mellon Asset Management | 194 536 | 13 234 | 31.12.2022 |
0,20 % | Group One Trading, L.P. | 188 342 | 43 659 | 31.12.2022 |
0,20 % | Schweizerische Nationalbank | 187 100 | 60 200 | 31.12.2022 |
0,19 % | Cabot Wealth Management, Inc. | 184 271 | 184 271 | 31.12.2022 |
0,19 % | Rice Hall James & Associates, LLC | 181 980 | -39 621 | 31.12.2022 |
0,19 % | Monticello Wealth Management, LLC | 180 555 | 0 | 31.12.2022 |
0,19 % | Charles Schwab Investment Management, Inc. | 176 464 | 11 358 | 31.12.2022 |
0,18 % | BlackRock Financial Management, Inc. | 168 536 | -10 213 | 31.12.2022 |
0,17 % | BlackRock Investment Management, LLC | 163 214 | 5 947 | 31.12.2022 |
0,16 % | Sigma Planning Corporation | 153 790 | 100 | 31.12.2022 |
0,16 % | Parametric Portfolio Associates LLC | 152 168 | 139 464 | 31.12.2022 |
0,14 % | Goldman Sachs & Company, Inc. | 128 006 | -21 008 | 31.12.2022 |
0,12 % | Susquehanna International Group, LLP | 114 911 | -68 229 | 31.12.2022 |
0,11 % | Qube Research & Technologies Ltd | 101 371 | 101 371 | 31.12.2022 |
0,10 % | Candriam Belgium S.A. | 97 509 | -110 142 | 31.12.2022 |
0,10 % | California State Teachers Retirement System | 92 471 | 22 342 | 31.12.2022 |
0,10 % | AllianceBernstein L.P. | 91 600 | 0 | 31.12.2022 |
0,10 % | Goldman Sachs Asset Management, L.P. | 91 264 | 14 955 | 31.12.2022 |
0,09 % | Credit Suisse Asset Management | 89 768 | 54 558 | 31.12.2022 |
0,09 % | ClariVest Asset Management LLC | 84 966 | 84 966 | 31.12.2022 |
0,09 % | Rhumbline Advisers Ltd. Partnership | 81 291 | 6 427 | 31.12.2022 |
0,08 % | State of Wisconsin Investment Board | 77 662 | 67 520 | 31.12.2022 |
0,08 % | Dimensional Fund Advisors, L.P. | 76 109 | -472 | 31.12.2022 |
0,07 % | Ramos (Eleanor L) | 70 000 | 0 | 21.03.2022 |
0,07 % | Macquarie Investment Management | 70 000 | 0 | 31.12.2022 |
0,07 % | Polen Capital Management, LLC | 67 333 | 0 | 31.01.2023 |
0,07 % | Russell Investments Trust Company | 67 333 | 0 | 31.12.2022 |
0,07 % | Jump Financial, LLC | 67 074 | 67 074 | 31.12.2022 |
0,07 % | Northern Trust Global Investments | 64 280 | 2 401 | 31.12.2022 |
0,06 % | State Street Global Advisors Ireland Limited | 60 275 | 267 | 31.01.2023 |
0,06 % | Wells Fargo Advisors | 59 848 | 55 738 | 31.12.2022 |
0,06 % | Mackenzie Financial Corporation | 57 141 | 47 909 | 31.12.2022 |
0,05 % | Assenagon Asset Management S.A. | 52 053 | -2 059 | 28.02.2023 |
0,05 % | BofA Global Research (US) | 49 706 | -17 471 | 31.12.2022 |
0,05 % | Victory Capital Management Inc. | 49 640 | 49 640 | 31.12.2022 |
0,05 % | Simplex Trading, LLC | 49 380 | 13 447 | 31.12.2022 |
0,05 % | LPL Financial LLC | 47 783 | 17 900 | 31.12.2022 |
0,05 % | Squarepoint Capital LLP | 44 899 | 44 899 | 31.12.2022 |
0,05 % | UBS Financial Services, Inc. | 43 249 | 11 297 | 31.12.2022 |
0,05 % | Citadel Advisors LLC | 42 764 | -191 162 | 31.12.2022 |
0,04 % | UBS Asset Management (Switzerland) | 41 628 | 11 912 | 31.12.2022 |
0,04 % | BlackRock Investment Management (UK) Ltd. | 41 626 | 10 970 | 31.12.2022 |
0,04 % | Morgan Stanley Smith Barney LLC | 39 846 | 537 | 31.12.2022 |
0,04 % | Mellon Investments Corporation | 39 699 | 7 186 | 31.12.2022 |
0,04 % | Bluestone (Jeffrey Ph.D.) | 39 571 | 0 | 21.03.2022 |
0,04 % | JPMorgan Private Bank (United States) | 36 850 | 4 610 | 31.12.2022 |
0,04 % | New York State Common Retirement Fund | 34 909 | 7 701 | 31.12.2022 |
0,04 % | PGIM Quantitative Solutions LLC | 33 950 | 450 | 31.12.2022 |
0,03 % | Engineers Gate Manager, L.P. | 32 148 | 32 148 | 31.12.2022 |
0,03 % | Gotham Asset Management, LLC | 31 595 | 31 595 | 31.12.2022 |
0,03 % | T. Rowe Price International Ltd | 31 137 | 1 578 | 31.12.2022 |
0,03 % | LifeSci Index Partners, LLC | 31 095 | 0 | 28.02.2023 |
0,03 % | Virtus Etf Advisers LLC | 31 095 | 31 095 | 31.12.2022 |
0,03 % | MetLife Investment Management, LLC | 30 784 | 0 | 31.12.2022 |
0,03 % | Mirae Asset Global Investments (USA) LLC | 30 005 | 5 164 | 31.12.2022 |
0,03 % | Cambridge Investment Research Advisors, Inc. | 29 895 | 13 900 | 31.12.2022 |
0,03 % | SunAmerica Asset Management, LLC | 29 840 | 1 829 | 31.12.2022 |
0,03 % | Granite Investment Partners, LLC | 28 883 | -714 | 31.01.2023 |
0,03 % | Legal & General Investment Management Ltd. | 28 154 | 7 143 | 31.12.2022 |
0,03 % | Aperio Group, LLC | 27 795 | 18 993 | 31.12.2022 |
0,03 % | DWS Investments UK Limited | 27 484 | 4 538 | 31.12.2022 |
0,03 % | SEI Investments Management Corporation | 27 341 | 1 401 | 31.01.2023 |
0,03 % | UBS Asset Management (UK) Ltd. | 26 417 | 26 417 | 31.12.2022 |
0,03 % | Hightower Advisors, LLC | 25 820 | 2 205 | 31.12.2022 |
0,03 % | Barclays Bank PLC | 24 846 | 24 846 | 31.12.2022 |
0,03 % | Manulife Investment Management (North America) Limited | 24 740 | 354 | 31.12.2022 |