6,22 % | New Enterprise Associates (NEA) | 4.007.977 | −756.463 | 28. 02. 2024. |
4,65 % | Octagon Capital Advisors LP | 3.000.000 | 0 | 31. 12. 2023. |
3,76 % | The Vanguard Group, Inc. | 2.421.869 | 0 | 31. 12. 2023. |
2,46 % | AXA Investment Managers UK Ltd. | 1.587.298 | −38.400 | 31. 12. 2023. |
14,81 % | BVF Partners L.P. | 9.544.262 | 0 | 31. 12. 2023. |
13,32 % | Invus Public Equities Advisors, LLC | 8.589.064 | 0 | 31. 12. 2023. |
1,43 % | Goldman Sachs & Company, Inc. | 919.355 | 124.861 | 31. 12. 2023. |
1,11 % | BlackRock Institutional Trust Company, N.A. | 718.329 | 1.577 | 31. 12. 2023. |
0,99 % | King (Rachel K) | 635.033 | 25.656 | 29. 03. 2024. |
0,84 % | Acadian Asset Management LLC | 541.176 | −302.875 | 31. 12. 2023. |
0,74 % | Geode Capital Management, L.L.C. | 478.883 | 19.038 | 31. 12. 2023. |
0,58 % | Rock (Edwin) | 375.403 | 0 | 15. 03. 2024. |
0,54 % | Magnani (John L) | 345.048 | 45.045 | 11. 11. 2022. |
0,35 % | Two Sigma Investments, LP | 225.021 | −108.051 | 31. 12. 2023. |
0,31 % | GSA Capital Partners LLP | 200.993 | 107.208 | 31. 12. 2023. |
0,31 % | Bridgeway Capital Management, LLC | 197.200 | 25.000 | 31. 12. 2023. |
0,29 % | State Street Global Advisors (US) | 186.765 | 0 | 31. 12. 2023. |
0,25 % | Rath (Chinmaya) | 161.178 | 161.178 | 23. 03. 2023. |
0,22 % | Connor, Clark & Lunn Investment Management Ltd. | 143.359 | −5.747 | 31. 12. 2023. |
0,22 % | Johnson (Bruce S) | 138.980 | 13.500 | 08. 05. 2023. |
0,19 % | Renaissance Technologies LLC | 124.444 | −76.663 | 31. 12. 2023. |
0,17 % | Susquehanna International Group, LLP | 111.491 | 111.491 | 31. 12. 2023. |
0,17 % | Welzia Management SGIIC S.A. | 110.429 | 26.650 | 31. 12. 2023. |
0,16 % | Taiko | 101.000 | 101.000 | 31. 12. 2023. |
0,16 % | Adage Capital Management, L.P. | 100.000 | 100.000 | 31. 12. 2023. |
0,16 % | Northern Trust Investments, Inc. | 99.939 | 5.018 | 31. 12. 2023. |
0,15 % | Junius (Daniel M) | 98.459 | 5.209 | 29. 03. 2024. |
0,15 % | ExodusPoint Capital Management, LP | 95.759 | 95.759 | 31. 12. 2023. |
0,15 % | Franklin Advisers, Inc. | 95.751 | −142 | 31. 12. 2023. |
0,11 % | Simplex Trading, LLC | 72.445 | 72.445 | 31. 12. 2023. |
0,10 % | Avantis Investors | 63.642 | 63.642 | 31. 03. 2024. |
0,09 % | Andrews Patricia S | 58.608 | 0 | 15. 03. 2024. |
0,09 % | Sargent Investment Group, LLC | 58.000 | 0 | 31. 12. 2023. |
0,09 % | Jane Street Capital, L.L.C. | 57.143 | 37.176 | 31. 12. 2023. |
0,08 % | Intellectus Partners, LLC | 50.720 | −11.255 | 31. 12. 2023. |
0,07 % | Letko, Brosseau & Associates Inc. | 45.250 | 0 | 31. 12. 2023. |
0,07 % | Hahn (Brian M) | 44.518 | 17.250 | 15. 03. 2024. |
0,06 % | LPL Financial LLC | 41.000 | 28.000 | 31. 12. 2023. |
0,06 % | Millennium Management LLC | 38.888 | −25.008 | 31. 12. 2023. |
0,06 % | IEQ Capital LLC | 38.363 | 0 | 31. 12. 2023. |
0,06 % | Koenig (Scott) | 36.750 | 0 | 15. 03. 2024. |
0,06 % | Goldberg (Mark Alan M.D.) | 36.325 | 4.584 | 29. 03. 2024. |
0,05 % | Morgan Stanley & Co. LLC | 34.511 | −5.874 | 31. 12. 2023. |
0,05 % | Virtu Americas LLC | 34.319 | 34.319 | 31. 12. 2023. |
0,05 % | Group One Trading, L.P. | 31.253 | 2.852 | 31. 12. 2023. |
0,04 % | Y-Intercept (Hong Kong) Ltd | 26.572 | 26.572 | 31. 12. 2023. |
0,04 % | Semerjian (Harout) | 25.000 | 0 | 15. 03. 2024. |
0,04 % | BNY Mellon Asset Management | 24.732 | −143 | 31. 12. 2023. |
0,04 % | Pearson (Timothy R) | 24.650 | 0 | 15. 03. 2024. |
0,03 % | Charles Schwab Investment Management, Inc. | 22.361 | 0 | 31. 12. 2023. |
0,03 % | Citi Investment Research (US) | 21.528 | 21.528 | 31. 12. 2023. |
0,03 % | BofA Global Research (US) | 19.990 | 11.766 | 31. 12. 2023. |
0,03 % | 683 Capital Management LLC | 19.384 | 19.384 | 31. 12. 2023. |
0,02 % | Tobias Financial Advisors, Inc. | 15.000 | 0 | 31. 12. 2023. |
0,02 % | Marshall Wace LLP | 12.885 | 12.885 | 31. 12. 2023. |
0,02 % | Pine Valley Investments LLC | 12.520 | 0 | 31. 12. 2023. |
0,02 % | Boothbay Fund Management, LLC | 12.464 | 12.464 | 31. 12. 2023. |
0,02 % | Blackstone Alternative Investment Advisors LLC | 12.200 | 9.668 | 31. 03. 2023. |
0,02 % | Northern Trust Global Investments | 11.315 | 0 | 31. 12. 2023. |
0,02 % | XTX Markets LLC | 11.093 | −21.629 | 31. 12. 2023. |
0,01 % | BlackRock Investment Management, LLC | 8.767 | −1.298 | 31. 12. 2023. |
0,01 % | BlackRock Investment Management (UK) Ltd. | 7.887 | 0 | 31. 12. 2023. |
0,01 % | Citadel Advisors LLC | 7.886 | 7.886 | 31. 12. 2023. |
0,01 % | Jackson (Scott Thomas) | 5.250 | 0 | 15. 03. 2024. |
0,01 % | Qube Research & Technologies Ltd | 4.853 | 4.454 | 31. 12. 2023. |
0,01 % | HFM Wealth Management | 3.500 | 0 | 31. 12. 2023. |
0,00 % | Tower Research Capital LLC | 2.882 | −1.780 | 31. 12. 2023. |
0,00 % | Truvestments Capital LLC | 2.057 | 0 | 31. 12. 2023. |
0,00 % | J.P. Morgan Securities LLC | 1.613 | 1.147 | 31. 12. 2023. |
0,00 % | Rhumbline Advisers Ltd. Partnership | 1.044 | 0 | 31. 12. 2023. |
0,00 % | Manulife Investment Management (North America) Limited | 933 | 0 | 31. 01. 2024. |
0,00 % | UBS Financial Services, Inc. | 683 | 683 | 31. 12. 2023. |
0,00 % | ORG Partners LLC | 500 | 500 | 31. 12. 2023. |
0,00 % | BNP Paribas Securities Corp. North America | 481 | 0 | 31. 12. 2023. |
0,00 % | Wells Fargo Bank, N.A. | 377 | 20 | 31. 12. 2023. |
0,00 % | Barclays Capital Inc. | 76 | −76 | 31. 12. 2023. |
0 % | Susquehanna Fundamental Investments, LLC | 0 | −90.876 | 30. 09. 2022. |
0 % | AE Wealth Management LLC | 0 | −26.898 | 31. 03. 2023. |
0 % | Wolverine Trading, LLC | 0 | −11.879 | 30. 06. 2023. |
0 % | Osaic Holdings, Inc. | 0 | −600 | 31. 03. 2023. |
0 % | Eversept Partners, LP | 0 | −100.579 | 31. 03. 2023. |
0 % | MJP Wealth Advisors | 0 | −101.000 | 31. 03. 2024. |
0 % | Chicago Partners Wealth Advisors | 0 | −20.000 | 31. 12. 2023. |
0 % | Cubist Systematic Strategies, LLC | 0 | −44.939 | 30. 06. 2023. |
0 % | Stratos Wealth Partners, Ltd. | 0 | −33.340 | 30. 09. 2023. |
0 % | DLD Asset Management, LP | 0 | −29.200 | 30. 06. 2023. |
0 % | Caption Management, LLC | 0 | −6.657 | 30. 06. 2023. |
0 % | Pura Vida Investments, LLC | 0 | −31.615 | 31. 03. 2023. |
0 % | Creative Planning, Inc. | 0 | −10.000 | 31. 12. 2023. |
0 % | Dimensional Fund Advisors, Ltd. | 0 | −2.193 | 28. 02. 2023. |
0 % | Commonwealth Financial Network | 0 | −10.000 | 31. 12. 2023. |
0 % | Parallax Volatility Advisers, L.P. | 0 | −37.604 | 30. 06. 2023. |
0 % | Signaturefd, LLC | 0 | −100 | 31. 12. 2023. |
0 % | Acuta Capital Partners, LLC | 0 | −27.500 | 31. 12. 2023. |
0 % | Archer Investment Corporation | 0 | −1.000 | 31. 03. 2023. |
0 % | Chatham Asset Management, L.L.C. | 0 | −29.200 | 30. 04. 2023. |
0 % | Apo Asset Management GmbH | 0 | −18.333 | 28. 02. 2023. |
0 % | RBC Capital Partners | 0 | −167 | 30. 09. 2023. |
0 % | Medical Strategy GmbH | 0 | −810.578 | 31. 03. 2023. |
0 % | Prentiss Smith & Company, Inc. | 0 | −15.120 | 31. 03. 2023. |