33.77667 % | Third Security, LLC | 96,445,913 | 85,470 | 3/9/2023 |
7.23091 % | Merck Serono SA | 20,647,152 | 0 | 12/31/2023 |
5.59771 % | Patient Capital Management, LLC | 15,983,700 | 2,230,524 | 12/31/2023 |
3.48787 % | BlackRock Institutional Trust Company, N.A. | 9,959,256 | 860,980 | 12/31/2023 |
2.36337 % | The Vanguard Group, Inc. | 6,748,359 | -202,515 | 12/31/2023 |
1.05810 % | Geode Capital Management, L.L.C. | 3,021,297 | 110,042 | 12/31/2023 |
0.99668 % | Millennium Management LLC | 2,845,911 | 1,423,117 | 12/31/2023 |
0.94016 % | State Street Global Advisors (US) | 2,684,533 | -81,934 | 12/31/2023 |
0.77785 % | Sabzevari (Helen) | 2,221,076 | 661,072 | 4/5/2024 |
0.70216 % | Iridian Asset Management LLC | 2,004,934 | -73,286 | 12/31/2023 |
0.42119 % | JPMorgan Asset Management U.K. Limited | 1,202,663 | 0 | 12/31/2023 |
0.36066 % | Hassan (Fred) | 1,029,834 | 150,892 | 3/14/2024 |
0.35867 % | Frank (Steven R) | 1,024,160 | 141,802 | 3/14/2024 |
0.35459 % | Opaleye Management Inc. | 1,012,500 | 84,000 | 12/31/2023 |
0.35352 % | D. E. Shaw & Co., L.P. | 1,009,447 | 355,755 | 12/31/2023 |
0.35351 % | Charles Schwab Investment Management, Inc. | 1,009,418 | -51,102 | 12/31/2023 |
0.34987 % | Northern Trust Investments, Inc. | 999,017 | -9,760 | 12/31/2023 |
0.30619 % | Renaissance Technologies LLC | 874,303 | -442,987 | 12/31/2023 |
0.25456 % | Morgan Stanley Smith Barney LLC | 726,877 | 2,202 | 12/31/2023 |
0.24690 % | Sanders Morris LLC | 705,000 | 705,000 | 3/31/2024 |
0.20013 % | GSA Capital Partners LLP | 571,463 | 236,674 | 12/31/2023 |
0.19960 % | Alvarez (Cesar Licinio) | 569,933 | 150,543 | 3/14/2024 |
0.19527 % | Perez Jeffrey Thomas | 557,561 | 98,658 | 4/5/2024 |
0.18846 % | Lehr Donald P | 538,126 | 109,210 | 4/5/2024 |
0.18630 % | Morgan Stanley & Co. LLC | 531,966 | 297,065 | 12/31/2023 |
0.18615 % | Citadel Advisors LLC | 531,520 | 234,718 | 12/31/2023 |
0.18387 % | Nuveen LLC | 525,028 | 0 | 12/31/2023 |
0.18193 % | EMFO, LLC | 519,475 | 94,475 | 12/31/2023 |
0.17622 % | Mitchell (Dean J) | 503,183 | 146,347 | 3/14/2024 |
0.16723 % | ClariVest Asset Management LLC | 477,505 | 11,361 | 12/31/2023 |
0.16685 % | BlackRock Financial Management, Inc. | 476,430 | -138,789 | 12/31/2023 |
0.16546 % | Turley (James S) | 472,441 | 150,543 | 3/14/2024 |
0.15851 % | Gupta (Vinita D) | 452,622 | 150,892 | 3/14/2024 |
0.13776 % | Kindler (Jeffrey B) | 393,363 | 155,088 | 3/14/2024 |
0.13404 % | BlackRock Investment Management, LLC | 382,745 | -10,142 | 12/31/2023 |
0.13063 % | Jacobs Levy Equity Management, Inc. | 373,013 | -314,781 | 12/31/2023 |
0.12580 % | BofA Global Research (US) | 359,210 | 138,143 | 12/31/2023 |
0.12495 % | Fore Capital, LLC | 356,791 | -70,000 | 12/31/2023 |
0.12433 % | MSD Partners, L.P. | 355,000 | -605,000 | 12/31/2023 |
0.11631 % | BNY Mellon Asset Management | 332,110 | -5,886 | 12/31/2023 |
0.11545 % | Shapiro (Robert B) | 329,656 | -56,043 | 3/31/2023 |
0.10929 % | Osaic Holdings, Inc. | 312,078 | -1,575 | 12/31/2023 |
0.10625 % | PanAgora Asset Management Inc. | 303,385 | 303,385 | 12/31/2023 |
0.08963 % | Fidelity Management & Research Company LLC | 255,916 | -57,449 | 12/31/2023 |
0.08810 % | Cetera Investment Advisers LLC | 251,575 | 10,750 | 12/31/2023 |
0.08435 % | Two Sigma Investments, LP | 240,859 | 18,015 | 12/31/2023 |
0.08033 % | Thomasian (Harry Jr.) | 229,376 | 68,325 | 4/5/2024 |
0.07514 % | UBS Financial Services, Inc. | 214,555 | 174,835 | 12/31/2023 |
0.07346 % | Shah (Rutul R.) | 209,746 | 76,272 | 4/5/2024 |
0.07284 % | Rhumbline Advisers Ltd. Partnership | 208,000 | -1,054 | 12/31/2023 |
0.07233 % | Barclays Bank PLC | 206,540 | 161,448 | 12/31/2023 |
0.07221 % | Jane Street Capital, L.L.C. | 206,197 | 173,228 | 12/31/2023 |
0.06978 % | Exchange Traded Concepts, LLC | 199,255 | 105,164 | 3/31/2024 |
0.06471 % | AllianceBernstein L.P. | 184,770 | -11,980 | 12/31/2023 |
0.06264 % | Goldman Sachs Asset Management, L.P. | 178,864 | -11,191 | 12/31/2023 |
0.05914 % | Assenagon Asset Management S.A. | 168,856 | 12,291 | 2/29/2024 |
0.05820 % | CIBC Private Wealth Management | 166,171 | 0 | 12/31/2023 |
0.05598 % | T. Rowe Price International Ltd | 159,848 | 0 | 12/31/2023 |
0.05261 % | Aperio Group, LLC | 150,224 | -80,263 | 12/31/2023 |
0.04943 % | BlackRock Asset Management Ireland Limited | 141,155 | 32,076 | 12/31/2023 |
0.04626 % | BlackRock Advisors (UK) Limited | 132,083 | 6,370 | 3/31/2024 |
0.03998 % | Mellon Investments Corporation | 114,169 | -2,951 | 12/31/2023 |
0.03771 % | Vident Investment Advisory, LLC | 107,685 | 107,685 | 6/30/2023 |
0.03719 % | Goldman Sachs & Company, Inc. | 106,206 | -88,593 | 12/31/2023 |
0.03661 % | Summit Trail Advisors, LLC | 104,529 | 0 | 12/31/2023 |
0.03211 % | JPMorgan Private Bank (United States) | 91,696 | 91,696 | 12/31/2023 |
0.03172 % | Susquehanna International Group, LLP | 90,561 | -61,452 | 12/31/2023 |
0.03123 % | Lexaurum Advisors, LLC | 89,166 | -8,600 | 3/31/2024 |
0.03007 % | Cary Street Partners Investment Advisory LLC | 85,873 | 0 | 12/31/2023 |
0.03007 % | Hightower Advisors, LLC | 85,853 | 12,348 | 12/31/2023 |
0.02964 % | Acuitas Investments LLC | 84,640 | 11,361 | 12/31/2023 |
0.02922 % | Northern Trust Global Investments | 83,435 | -2,242 | 12/31/2023 |
0.02712 % | T. Rowe Price Associates, Inc. | 77,440 | 0 | 12/31/2023 |
0.02674 % | SG Americas Securities, L.L.C. | 76,352 | 8,478 | 12/31/2023 |
0.02573 % | Virtus Etf Advisers LLC | 73,477 | -6,277 | 12/31/2023 |
0.02503 % | Tudor Investment Corporation | 71,464 | 0 | 12/31/2023 |
0.02430 % | Cambridge Investment Research Advisors, Inc. | 69,384 | -12,150 | 12/31/2023 |
0.02356 % | Principal Global Investors (Equity) | 67,271 | -6,818 | 12/31/2023 |
0.02352 % | SunAmerica Asset Management, LLC | 67,160 | -272 | 12/31/2023 |
0.02317 % | MetLife Investment Management, LLC | 66,164 | 0 | 12/31/2023 |
0.02317 % | XTX Markets LLC | 66,162 | -61,413 | 12/31/2023 |
0.02315 % | American Financial Group, Inc. | 66,114 | 0 | 12/31/2023 |
0.02295 % | Virtu Americas LLC | 65,526 | 65,526 | 12/31/2023 |
0.02243 % | New York State Common Retirement Fund | 64,042 | -168 | 12/31/2023 |
0.02058 % | Dimensional Fund Advisors, L.P. | 58,755 | 0 | 12/31/2023 |
0.02008 % | Commonwealth Financial Network | 57,340 | -3,359 | 12/31/2023 |
0.02005 % | DWS Investments UK Limited | 57,248 | 0 | 12/31/2023 |
0.01996 % | Wells Fargo Advisors | 57,003 | -164 | 12/31/2023 |
0.01969 % | Vaughan Nelson Investment Management, L.P. | 56,210 | 0 | 12/31/2023 |
0.01890 % | Voya Investment Management LLC | 53,961 | -5,106 | 12/31/2023 |
0.01864 % | LMR Partners LLP | 53,230 | 3,108 | 12/31/2023 |
0.01772 % | Cerity Partners LLC | 50,585 | 1,000 | 12/31/2023 |
0.01758 % | State Teachers Retirement System of Ohio | 50,200 | 0 | 12/31/2023 |
0.01751 % | Greenwich Wealth Management LLC | 50,000 | 0 | 12/31/2023 |
0.01718 % | Synovus Securities, Inc. | 49,065 | 0 | 12/31/2023 |
0.01713 % | J.P. Morgan Securities plc | 48,917 | -596 | 12/31/2023 |
0.01699 % | Diametric Capital | 48,518 | 48,518 | 12/31/2023 |
0.01555 % | Aptus Capital Advisors, LLC | 44,399 | 0 | 12/31/2023 |
0.01555 % | Guardian Wealth Advisors, LLC (North Carolina) | 44,399 | 0 | 12/31/2023 |
0.01503 % | Carson Wealth Management Group | 42,912 | 0 | 3/31/2024 |