7.61846 % | Pfizer Inc | 5,376,344 | 0 | 3/31/2024 |
7.49003 % | Nextech Invest, Ltd. | 5,285,714 | 0 | 6/30/2024 |
6.97139 % | Fidelity Management & Research Company LLC | 4,919,713 | -104,240 | 6/30/2024 |
6.22719 % | VR Adviser, LLC | 4,394,527 | 0 | 6/30/2024 |
5.87056 % | Frazier Life Sciences Management, L.P. | 4,142,855 | 0 | 6/30/2024 |
5.80051 % | BlackRock Institutional Trust Company, N.A. | 4,093,420 | 1,200,147 | 6/30/2024 |
5.66813 % | Viking Global Investors LP | 4,000,000 | 0 | 6/30/2024 |
5.01740 % | The Column Group LP | 3,540,777 | 0 | 6/30/2024 |
4.84351 % | EcoR1 Capital, LLC | 3,418,068 | 0 | 6/30/2024 |
4.52038 % | The Vanguard Group, Inc. | 3,190,034 | 307,979 | 6/30/2024 |
4.47798 % | Alkeon Capital Management LLC | 3,160,112 | 71,526 | 6/30/2024 |
3.19715 % | State Street Global Advisors (US) | 2,256,228 | 540,147 | 6/30/2024 |
2.83407 % | Commodore Capital LP | 2,000,000 | 0 | 6/30/2024 |
2.45511 % | Boxer Capital, L.L.C. | 1,732,571 | 0 | 6/30/2024 |
2.14816 % | First Turn Management, LLC | 1,515,960 | 418,389 | 6/30/2024 |
2.12555 % | New Enterprise Associates (NEA) | 1,500,000 | 0 | 6/30/2024 |
1.88068 % | Norges Bank Investment Management (NBIM) | 1,327,195 | 1,327,195 | 6/30/2024 |
1.80462 % | ArrowMark Colorado Holdings, LLC | 1,273,522 | -237,339 | 6/30/2024 |
1.79917 % | Vivo Capital, LLC | 1,269,676 | 419,995 | 6/30/2024 |
1.73259 % | Geode Capital Management, L.L.C. | 1,222,692 | 311,059 | 6/30/2024 |
1.63720 % | T. Rowe Price Associates, Inc. | 1,155,372 | -390,441 | 6/30/2024 |
1.52446 % | SilverArc Capital Management, LLC | 1,075,812 | -37,195 | 6/30/2024 |
1.42777 % | Invus Financial Advisors, LLC | 1,007,575 | 0 | 6/30/2024 |
1.40203 % | Euclidean Capital, L.L.C. | 989,410 | 0 | 6/30/2024 |
1.10854 % | Millennium Management LLC | 782,299 | 585,447 | 6/30/2024 |
1.10585 % | Adage Capital Management, L.P. | 780,400 | -250,000 | 6/30/2024 |
1.06770 % | Franklin Advisers, Inc. | 753,475 | 3,139 | 6/30/2024 |
1.03237 % | Chacko (Jacob M) | 728,544 | -32,236 | 3/31/2024 |
0.91255 % | Oppenheimer Asset Management Inc. | 643,984 | 28,474 | 6/30/2024 |
0.85344 % | Memorial Sloan-Kettering Cancer Center | 602,272 | 0 | 9/30/2023 |
0.66128 % | Dimensional Fund Advisors, L.P. | 466,662 | 305,860 | 6/30/2024 |
0.59446 % | BlackRock Financial Management, Inc. | 419,508 | 299,294 | 6/30/2024 |
0.57390 % | Altium Capital Management LP | 405,000 | 0 | 6/30/2024 |
0.54405 % | Morgan Stanley & Co. LLC | 383,938 | 183,650 | 6/30/2024 |
0.48550 % | Two Sigma Investments, LP | 342,614 | 204,505 | 6/30/2024 |
0.45917 % | Northern Trust Investments, Inc. | 324,033 | 6,900 | 6/30/2024 |
0.42745 % | Monaco asset management S.A.M. | 301,650 | 171,650 | 6/30/2024 |
0.40683 % | OrbiMed Advisors, LLC | 287,100 | 0 | 6/30/2024 |
0.39179 % | BofA Global Research (US) | 276,489 | 75,367 | 6/30/2024 |
0.33999 % | Goldman Sachs & Company, Inc. | 239,934 | 96,635 | 6/30/2024 |
0.32418 % | Heyman (Richard A) | 228,772 | 0 | 3/31/2024 |
0.25686 % | BlackRock Investment Management, LLC | 181,263 | 74,011 | 6/30/2024 |
0.23440 % | Nuveen LLC | 165,415 | 30,406 | 6/30/2024 |
0.23098 % | Soleus Capital Management, L.P. | 163,000 | -258,000 | 6/30/2024 |
0.23008 % | Charles Schwab Investment Management, Inc. | 162,366 | 57,822 | 6/30/2024 |
0.22093 % | Fred Alger Management, LLC | 155,912 | -64,031 | 6/30/2024 |
0.20397 % | Driehaus Capital Management, LLC | 143,943 | 0 | 6/30/2024 |
0.19753 % | TD Asset Management Inc. | 139,400 | -69,200 | 6/30/2024 |
0.19550 % | Hennion & Walsh Asset Management, Inc. | 137,962 | 35,528 | 9/30/2024 |
0.18613 % | Manulife Investment Management (North America) Limited | 131,350 | 9,424 | 6/30/2024 |
0.18557 % | BNY Mellon Asset Management | 130,958 | 49,258 | 6/30/2024 |
0.17404 % | Wellington Management Company, LLP | 122,823 | 10,850 | 6/30/2024 |
0.16467 % | Rafferty Asset Management LLC | 116,208 | 5,062 | 6/30/2024 |
0.16206 % | UBS O'Connor LLC | 114,366 | 22,000 | 6/30/2024 |
0.14559 % | Jane Street Capital, L.L.C. | 102,741 | 102,741 | 6/30/2024 |
0.13604 % | Acuta Capital Partners, LLC | 96,000 | -7,992 | 6/30/2024 |
0.13582 % | Victory Capital Management Inc. | 95,850 | 7,310 | 6/30/2024 |
0.13136 % | Rhumbline Advisers Ltd. Partnership | 92,702 | 32,402 | 6/30/2024 |
0.11932 % | American Century Investment Management, Inc. | 84,201 | 11,034 | 6/30/2024 |
0.11876 % | Piscitelli (Dominic G.) | 83,809 | 7,764 | 3/31/2024 |
0.11510 % | Qube Research & Technologies Ltd | 81,227 | 28,184 | 6/30/2024 |
0.11451 % | UBS Financial Services, Inc. | 80,807 | -13,254 | 6/30/2024 |
0.10098 % | Wilmington Trust Investment Advisors, Inc. | 71,259 | 12 | 6/30/2024 |
0.10013 % | BlackRock Investment Management (UK) Ltd. | 70,664 | 62,389 | 6/30/2024 |
0.09865 % | SG Americas Securities, L.L.C. | 69,620 | 69,620 | 9/30/2024 |
0.09395 % | Schweizerische Nationalbank | 66,300 | 66,300 | 6/30/2024 |
0.09033 % | Avantis Investors | 63,749 | 23,617 | 3/31/2024 |
0.07868 % | Mellon Investments Corporation | 55,526 | 28,052 | 6/30/2024 |
0.07197 % | Barclays Bank PLC | 50,787 | 17,633 | 6/30/2024 |
0.06888 % | Dimensional Fund Advisors, Ltd. | 48,612 | 2,990 | 9/30/2024 |
0.06660 % | Renaissance Technologies LLC | 47,000 | -63,900 | 6/30/2024 |
0.06242 % | AllianceBernstein L.P. | 44,050 | 13,890 | 6/30/2024 |
0.05578 % | BlackRock Advisors (UK) Limited | 39,367 | 867 | 9/30/2024 |
0.05509 % | Goldman Sachs Asset Management, L.P. | 38,876 | 12,497 | 6/30/2024 |
0.05381 % | Legal & General Investment Management Ltd. | 37,972 | 34,719 | 6/30/2024 |
0.05229 % | Atom Investors LP | 36,901 | 5,506 | 6/30/2024 |
0.05192 % | Corton Capital Inc | 36,643 | 36,643 | 6/30/2024 |
0.05170 % | BlackRock Asset Management Ireland Limited | 36,482 | 693 | 6/30/2024 |
0.05133 % | State of Wisconsin Investment Board | 36,223 | 36,223 | 6/30/2024 |
0.05112 % | MetLife Investment Management, LLC | 36,078 | 15,341 | 6/30/2024 |
0.05101 % | Dafna Capital Management, LLC | 36,000 | 36,000 | 6/30/2024 |
0.05086 % | UBS Fund Management (Switzerland) AG | 35,889 | 8,294 | 6/30/2024 |
0.04974 % | California State Teachers Retirement System | 35,104 | 31,180 | 6/30/2024 |
0.04959 % | Northern Trust Global Investments | 34,993 | -1,215 | 6/30/2024 |
0.04850 % | Verition Fund Management LLC | 34,228 | 34,228 | 6/30/2024 |
0.04824 % | Susquehanna International Group, LLP | 34,045 | 34,045 | 6/30/2024 |
0.04816 % | Squarepoint Capital LLP | 33,984 | 16,613 | 6/30/2024 |
0.04797 % | T. Rowe Price International Ltd | 33,855 | 12,932 | 6/30/2024 |
0.04732 % | Tudor Investment Corporation | 33,391 | 4,186 | 6/30/2024 |
0.04694 % | Corebridge Financial Inc | 33,124 | 33,124 | 6/30/2024 |
0.04517 % | Parametric Portfolio Associates LLC | 31,877 | -61,321 | 6/30/2024 |
0.04156 % | Aperio Group, LLC | 29,331 | 7,886 | 6/30/2024 |
0.04016 % | Assenagon Asset Management S.A. | 28,338 | 926 | 9/30/2024 |
0.03895 % | Citi Investment Research (US) | 27,490 | -106,416 | 6/30/2024 |
0.03718 % | JPMorgan Private Bank (United States) | 26,239 | 10,935 | 6/30/2024 |
0.03672 % | Mirae Asset Global Investments (USA) LLC | 25,912 | 25,912 | 6/30/2024 |
0.03596 % | Wells Fargo Bank, N.A. | 25,379 | 11,562 | 6/30/2024 |
0.03508 % | DWS Investments UK Limited | 24,759 | 4,036 | 6/30/2024 |
0.03374 % | Multani Pratik S | 23,809 | 7,764 | 3/31/2024 |
0.03233 % | Alpine Global Management, LLC | 22,815 | 22,815 | 6/30/2024 |