4.34783 % | Fidelity Management & Research Company LLC | 16,025,235 | 1,110,619 | 6/30/2024 |
3.11643 % | T. Rowe Price Associates, Inc. | 11,486,539 | 540,128 | 6/30/2024 |
2.03672 % | RA Capital Management, LP | 7,506,934 | 645,837 | 6/30/2024 |
1.80056 % | HHLR Advisors, Ltd. | 6,636,496 | 651,946 | 6/30/2024 |
1.29476 % | Westfield Capital Management Company, L.P. | 4,772,209 | 2,532,435 | 6/30/2024 |
0.93699 % | BlackRock Institutional Trust Company, N.A. | 3,453,547 | 321,269 | 6/30/2024 |
0.76221 % | Wellington Management Company, LLP | 2,809,368 | 194,945 | 6/30/2024 |
0.64004 % | Janus Henderson Investors | 2,359,056 | 345,044 | 6/30/2024 |
0.61045 % | Genscript Biotech Corp | 2,250,000 | 0 | 12/31/2023 |
0.60301 % | Capital Research Global Investors | 2,222,566 | 62,732 | 9/30/2024 |
0.58677 % | Capital International Investors | 2,162,711 | -18,363 | 6/30/2024 |
0.53146 % | MFS Investment Management | 1,958,846 | 69,300 | 6/30/2024 |
0.45301 % | Braidwell LP | 1,669,720 | 425,925 | 6/30/2024 |
0.45002 % | Millennium Management LLC | 1,658,681 | 1,287,590 | 6/30/2024 |
0.43311 % | Fidelity Institutional Asset Management | 1,596,364 | 363,948 | 6/30/2024 |
0.41751 % | Federated Hermes Global Investment Management Corp. | 1,538,845 | 1,785 | 6/30/2024 |
0.39201 % | Citadel Advisors LLC | 1,444,863 | 300,387 | 6/30/2024 |
0.32647 % | Paradigm BioCapital Advisors LP | 1,203,308 | -778,698 | 6/30/2024 |
0.31846 % | TimesSquare Capital Management, LLC | 1,173,766 | 15,266 | 6/30/2024 |
0.30807 % | State Street Global Advisors (US) | 1,135,487 | 87,485 | 6/30/2024 |
0.29515 % | AllianceBernstein L.P. | 1,087,849 | -25,309 | 6/30/2024 |
0.28833 % | ArrowMark Colorado Holdings, LLC | 1,062,734 | 15,995 | 6/30/2024 |
0.27995 % | Matthews International Capital Management, L.L.C. | 1,031,851 | 9,071 | 9/30/2024 |
0.27302 % | BlackRock Financial Management, Inc. | 1,006,297 | 22,692 | 6/30/2024 |
0.22101 % | Johnson & Johnson Innovation-JJDC, Inc. | 814,586 | 0 | 6/30/2024 |
0.18123 % | Goldman Sachs & Company, Inc. | 667,990 | 357,582 | 6/30/2024 |
0.17711 % | Columbia Threadneedle Investments (US) | 652,780 | 578,012 | 6/30/2024 |
0.16279 % | Boxer Capital, L.L.C. | 600,000 | 0 | 6/30/2024 |
0.15210 % | BlackRock Advisors (UK) Limited | 560,596 | 15,414 | 9/30/2024 |
0.14689 % | BlackRock Asset Management Ireland Limited | 541,419 | 8,283 | 6/30/2024 |
0.14425 % | Capital International, Inc. | 531,660 | 77,996 | 6/30/2024 |
0.13723 % | Rock Springs Capital Management LP | 505,786 | 6,300 | 6/30/2024 |
0.12999 % | Legal & General Investment Management Ltd. | 479,118 | 62,037 | 6/30/2024 |
0.12956 % | Geode Capital Management, L.L.C. | 477,527 | 14,920 | 6/30/2024 |
0.12931 % | Artisan Partners Limited Partnership | 476,615 | -15,484 | 6/30/2024 |
0.12262 % | Balyasny Asset Management LP | 451,965 | 451,965 | 6/30/2024 |
0.12250 % | BlackRock Investment Management (UK) Ltd. | 451,507 | 26,262 | 6/30/2024 |
0.10798 % | Avidity Partners Management LP | 398,000 | -270,300 | 6/30/2024 |
0.10734 % | Principal Global Investors (Equity) | 395,629 | 0 | 9/30/2024 |
0.10400 % | Candriam Luxembourg S.A. | 383,333 | 44,537 | 9/30/2024 |
0.10019 % | Bellevue Asset Management AG | 369,270 | 76,000 | 6/30/2024 |
0.09673 % | Tri Locum Partners LP | 356,532 | 72,759 | 6/30/2024 |
0.09310 % | Cutter Capital Management, LP | 343,130 | 263,300 | 6/30/2024 |
0.08607 % | BofA Global Research (US) | 317,247 | -87,594 | 6/30/2024 |
0.08391 % | Baron Capital Management, Inc. | 309,264 | 32,437 | 6/30/2024 |
0.08262 % | Point72 Asset Management, L.P. | 304,520 | 197,520 | 6/30/2024 |
0.07135 % | JPMorgan Asset Management U.K. Limited | 262,972 | -50,550 | 6/30/2024 |
0.07082 % | Candriam Belgium S.A. | 261,035 | 40,003 | 6/30/2024 |
0.06946 % | Putnam Investment Management, L.L.C. | 256,000 | 0 | 8/31/2024 |
0.06828 % | Magnetar Capital Partners LP | 251,667 | 251,667 | 6/30/2024 |
0.06473 % | Nordea Funds Oy | 238,600 | 223,613 | 6/30/2024 |
0.06377 % | Polar Asset Management Partners Inc. | 235,059 | 198,159 | 6/30/2024 |
0.05606 % | Polar Capital LLP | 206,632 | 50,557 | 6/30/2024 |
0.05291 % | Ally Bridge Group NY LLC | 195,000 | 195,000 | 6/30/2024 |
0.05003 % | Russell Investments Trust Company | 184,414 | 673 | 6/30/2024 |
0.04777 % | Morgan Stanley & Co. LLC | 176,088 | 54,443 | 6/30/2024 |
0.04489 % | Bridgewater Associates, LP | 165,459 | -43,441 | 6/30/2024 |
0.04410 % | Sumitomo Mitsui Trust Bank, Limited | 162,555 | -2,018 | 6/30/2024 |
0.04341 % | Schweizerische Nationalbank | 159,994 | 0 | 6/30/2024 |
0.04205 % | Senator Investment Group LP | 155,000 | -10,000 | 6/30/2024 |
0.04196 % | Superstring Capital Management LP | 154,665 | 154,665 | 6/30/2024 |
0.04180 % | CenterBook Partners LP | 154,074 | 154,074 | 6/30/2024 |
0.03825 % | TD Asset Management Inc. | 140,992 | -45,400 | 6/30/2024 |
0.03689 % | Nordea Investment Management AB (Denmark) | 135,987 | 678 | 8/31/2024 |
0.03662 % | Walleye Capital LLC | 134,978 | 132,762 | 6/30/2024 |
0.03474 % | Mirae Asset Global Investments (USA) LLC | 128,038 | 102,087 | 6/30/2024 |
0.03446 % | LMR Partners LLP | 127,000 | 25,100 | 6/30/2024 |
0.03246 % | UBS Financial Services, Inc. | 119,639 | -8,477 | 6/30/2024 |
0.03177 % | T. Rowe Price Japan, Inc. | 117,100 | 6,800 | 4/30/2024 |
0.03166 % | HSBC Private Bank (Suisse) S.A. | 116,706 | 17,428 | 6/30/2024 |
0.03101 % | BlackRock (Netherlands) B.V. | 114,299 | -28,036 | 6/30/2024 |
0.03060 % | Schroder Investment Management Ltd. (SIM) | 112,789 | -1,937 | 6/30/2024 |
0.03002 % | The Vanguard Group, Inc. | 110,658 | -5,620 | 6/30/2024 |
0.02978 % | Polen Capital Management, LLC | 109,760 | 0 | 8/31/2024 |
0.02940 % | HSBC Global Asset Management (UK) Limited | 108,376 | 1,414 | 6/30/2024 |
0.02933 % | DWS Investments UK Limited | 108,104 | -12,815 | 6/30/2024 |
0.02909 % | Barclays Capital Inc. | 107,213 | -12,294 | 6/30/2024 |
0.02774 % | UBS Fund Management (Switzerland) AG | 102,243 | -15,262 | 6/30/2024 |
0.02713 % | Woodline Partners LP | 100,001 | -6 | 6/30/2024 |
0.02678 % | Empire Life Investments Inc. | 98,688 | 42,368 | 9/30/2024 |
0.02674 % | Decheng Capital LLC | 98,558 | 12,195 | 6/30/2024 |
0.02663 % | Teacher Retirement System of Texas | 98,136 | -336 | 6/30/2024 |
0.02634 % | Fidelity Management & Research (Hong Kong) Limited | 97,100 | 0 | 8/31/2024 |
0.02627 % | Parametric Portfolio Associates LLC | 96,808 | -6,797 | 6/30/2024 |
0.02623 % | Nuveen LLC | 96,686 | -2,300 | 6/30/2024 |
0.02545 % | Capital International Sarl | 93,786 | 10,785 | 6/30/2024 |
0.02382 % | Thrivent Asset Management, LLC | 87,792 | -31,053 | 6/30/2024 |
0.02369 % | Pictet Asset Management Ltd. | 87,322 | 836 | 6/30/2024 |
0.02344 % | Manulife Investment Management (North America) Limited | 86,410 | -466,003 | 6/30/2024 |
0.02239 % | Jane Street Capital, L.L.C. | 82,541 | 43,143 | 6/30/2024 |
0.02224 % | BlackRock Japan Co., Ltd. | 81,970 | 303 | 6/30/2024 |
0.02185 % | Allianz Global Investors GmbH | 80,535 | 26,645 | 8/31/2024 |
0.02065 % | J.P. Morgan Securities plc | 76,113 | 9,700 | 6/30/2024 |
0.01928 % | EFG Asset Management (UK) Limited | 71,079 | -1,854 | 6/30/2024 |
0.01928 % | EFG Asset Management (North America) Corp | 71,079 | 1,820 | 6/30/2024 |
0.01883 % | Squarepoint Capital LLP | 69,400 | -32,334 | 6/30/2024 |
0.01786 % | Bessemer Trust Company, N.A. (US) | 65,834 | 0 | 7/31/2024 |
0.01743 % | Huang (Ying) | 64,246 | 58,593 | 12/31/2023 |
0.01734 % | OP Varainhoito Oy | 63,894 | 0 | 8/31/2024 |
0.01684 % | Mellon Investments Corporation | 62,052 | 17,183 | 6/30/2024 |