14.86890 % | Fidelity Management & Research Company LLC | 4,276,296 | 39,619 | 6/30/2024 |
12.78486 % | BlackRock Institutional Trust Company, N.A. | 3,676,927 | 2,055,359 | 6/30/2024 |
9.96314 % | The Vanguard Group, Inc. | 2,865,400 | 436,357 | 6/30/2024 |
8.45967 % | Avoro Capital Advisors LLC | 2,433,000 | -122,555 | 6/30/2024 |
5.91885 % | Krishnan (Krish S) | 1,702,262 | -25,000 | 9/12/2024 |
5.53158 % | Krishnan (Suma M) | 1,590,882 | -25,000 | 9/12/2024 |
5.05150 % | State Street Global Advisors (US) | 1,452,811 | 119,936 | 9/30/2024 |
3.55034 % | Redmile Group, LLC | 1,021,078 | -487,172 | 6/30/2024 |
3.43693 % | Frazier Life Sciences Management, L.P. | 988,460 | 0 | 6/30/2024 |
3.05340 % | Capital World Investors | 878,158 | 781,011 | 6/30/2024 |
3.04939 % | Capital Research Global Investors | 877,006 | 0 | 9/30/2024 |
2.03132 % | T. Rowe Price Associates, Inc. | 584,209 | -60,085 | 6/30/2024 |
2.01826 % | Dimensional Fund Advisors, L.P. | 580,452 | 7,537 | 6/30/2024 |
2.01745 % | Geode Capital Management, L.L.C. | 580,220 | 54,475 | 6/30/2024 |
1.81187 % | Hood River Capital Management LLC | 521,093 | 25,507 | 6/30/2024 |
1.80942 % | Jennison Associates LLC | 520,390 | -150,345 | 6/30/2024 |
1.36383 % | Lord, Abbett & Co. LLC | 392,238 | -99,994 | 6/30/2024 |
1.11063 % | Goldman Sachs & Company, Inc. | 319,416 | -1,227 | 6/30/2024 |
1.01501 % | Woodline Partners LP | 291,918 | 16,463 | 6/30/2024 |
0.94079 % | Nuveen LLC | 270,572 | 28,056 | 6/30/2024 |
0.79304 % | Morgan Stanley & Co. LLC | 228,078 | 72,705 | 6/30/2024 |
0.77148 % | UBS Asset Management (UK) Ltd. | 221,879 | 212,304 | 6/30/2024 |
0.76648 % | Charles Schwab Investment Management, Inc. | 220,439 | 31,536 | 6/30/2024 |
0.69239 % | Northern Trust Investments, Inc. | 199,131 | 12,761 | 6/30/2024 |
0.66591 % | SEB Investment Management AB | 191,515 | -26,232 | 6/30/2024 |
0.63664 % | Invesco Advisers, Inc. | 183,097 | 139,741 | 6/30/2024 |
0.61369 % | Fidelity Investments Canada ULC | 176,498 | 1,567 | 6/30/2024 |
0.59087 % | Baker Bros. Advisors LP | 169,934 | 0 | 6/30/2024 |
0.51794 % | Medical Strategy GmbH | 148,959 | -800 | 6/30/2024 |
0.50023 % | Victory Capital Management Inc. | 143,865 | 9,045 | 6/30/2024 |
0.47786 % | Pictet Asset Management Ltd. | 137,433 | -5,527 | 6/30/2024 |
0.47457 % | Eventide Asset Management, LLC | 136,485 | 0 | 6/30/2024 |
0.47221 % | C WorldWide Asset Management Fondsmaeglerselskab A/S | 135,809 | 0 | 6/30/2024 |
0.45148 % | Mellon Investments Corporation | 129,846 | 94,590 | 6/30/2024 |
0.43811 % | Soleus Capital Management, L.P. | 126,000 | 41,900 | 6/30/2024 |
0.42931 % | Principal Global Investors (Equity) | 123,469 | 117,510 | 6/30/2024 |
0.42487 % | Franklin Advisers, Inc. | 122,193 | 45,701 | 6/30/2024 |
0.41289 % | Driehaus Capital Management, LLC | 118,746 | 8,547 | 6/30/2024 |
0.38840 % | Allspring Global Investments, LLC | 111,705 | -64,741 | 9/30/2024 |
0.37977 % | First Turn Management, LLC | 109,222 | -21,628 | 6/30/2024 |
0.37612 % | JPMorgan Asset Management U.K. Limited | 108,173 | -42,968 | 6/30/2024 |
0.37330 % | Janney (Daniel Spencer) | 107,362 | -125,000 | 3/25/2024 |
0.37267 % | Braidwell LP | 107,179 | -69,910 | 6/30/2024 |
0.36707 % | Rock Springs Capital Management LP | 105,569 | 1,600 | 6/30/2024 |
0.35784 % | Goldman Sachs Asset Management, L.P. | 102,915 | -11,016 | 6/30/2024 |
0.34925 % | Columbia Threadneedle Investments (US) | 100,443 | 57,052 | 6/30/2024 |
0.33505 % | BlackRock Financial Management, Inc. | 96,361 | 22,914 | 6/30/2024 |
0.32928 % | Handelsbanken Kapitalf¿rvaltning AB | 94,700 | -11,800 | 9/30/2024 |
0.31982 % | Invesco Capital Management LLC | 91,980 | 45,708 | 6/30/2024 |
0.29630 % | S Squared Technology, LLC | 85,215 | -5,000 | 6/30/2024 |
0.29555 % | Integral Health Asset Management, LLC | 85,000 | 5,000 | 6/30/2024 |
0.28873 % | TimesSquare Capital Management, LLC | 83,039 | -14,122 | 6/30/2024 |
0.27361 % | Rossi (Dino A) | 78,691 | -5,000 | 9/13/2024 |
0.27213 % | Parametric Portfolio Associates LLC | 78,266 | 31,382 | 6/30/2024 |
0.27063 % | Jane Street Capital, L.L.C. | 77,832 | -15,913 | 6/30/2024 |
0.26730 % | BofA Global Research (US) | 76,876 | 12,555 | 6/30/2024 |
0.26516 % | Eagle Asset Management, Inc. | 76,259 | 76,259 | 6/30/2024 |
0.25340 % | Voya Investment Management LLC | 72,877 | 13,896 | 6/30/2024 |
0.25312 % | BlackRock Investment Management, LLC | 72,798 | 20,060 | 6/30/2024 |
0.24925 % | Rhumbline Advisers Ltd. Partnership | 71,685 | 39,586 | 6/30/2024 |
0.24815 % | BlackRock Advisors (UK) Limited | 71,368 | 1,238 | 9/30/2024 |
0.24079 % | AHL Partners LLP | 69,250 | -26,608 | 6/30/2024 |
0.22984 % | Legal & General Investment Management Ltd. | 66,103 | 46,553 | 6/30/2024 |
0.22869 % | Decheng Capital LLC | 65,772 | 0 | 6/30/2024 |
0.22854 % | BlackRock Asset Management Ireland Limited | 65,728 | 36,994 | 6/30/2024 |
0.22809 % | Nuveen Asset Management, LLC | 65,598 | -22,328 | 6/30/2024 |
0.22601 % | Corient Private Wealth LLC | 65,000 | 29,028 | 6/30/2024 |
0.21471 % | BNY Mellon Asset Management | 61,750 | 10,492 | 6/30/2024 |
0.20796 % | Balyasny Asset Management LP | 59,810 | -64,393 | 6/30/2024 |
0.20195 % | TD Asset Management Inc. | 58,080 | -11,082 | 6/30/2024 |
0.20065 % | Putnam Investment Management, L.L.C. | 57,707 | 4,414 | 6/30/2024 |
0.19004 % | PSP Investments | 54,656 | 54,656 | 6/30/2024 |
0.16187 % | Scout Investments, Inc. | 46,553 | -4,424 | 6/30/2024 |
0.16026 % | International Biotechnology Trust PLC | 46,092 | 147 | 9/30/2023 |
0.14970 % | abrdn Inc. | 43,054 | -318 | 9/30/2024 |
0.14812 % | Oberweis Asset Management, Inc. | 42,600 | 6,900 | 6/30/2024 |
0.14534 % | Rafferty Asset Management LLC | 41,800 | -11,567 | 6/30/2024 |
0.14261 % | Manulife Investment Management (North America) Limited | 41,015 | -283 | 6/30/2024 |
0.13032 % | Schroder Investment Management Ltd. (SIM) | 37,480 | -2,004 | 6/30/2024 |
0.12978 % | Mutual of America Capital Management LLC | 37,324 | 3,135 | 6/30/2024 |
0.12909 % | GW&K Investment Management, LLC | 37,126 | -402 | 6/30/2024 |
0.12881 % | Janney Montgomery Scott LLC | 37,047 | 5,415 | 9/30/2024 |
0.12620 % | SEI Investments Management Corporation | 36,295 | 6,484 | 6/30/2024 |
0.12587 % | Schweizerische Nationalbank | 36,200 | 0 | 6/30/2024 |
0.12288 % | J.P. Morgan Securities plc | 35,341 | 29,124 | 6/30/2024 |
0.12078 % | Segall Bryant & Hamill, LLC | 34,737 | 34,737 | 6/30/2024 |
0.10476 % | First Trust Advisors L.P. | 30,129 | 91 | 9/30/2024 |
0.10419 % | OrbiMed Advisors, LLC | 29,966 | -7,200 | 6/30/2024 |
0.10334 % | AllianceBernstein L.P. | 29,720 | 5,960 | 6/30/2024 |
0.10029 % | EAM Global Investors LLC | 28,843 | 1 | 6/30/2024 |
0.09929 % | UBS Financial Services, Inc. | 28,556 | -22,472 | 6/30/2024 |
0.09917 % | Epoch Investment Partners, Inc. | 28,522 | -4,773 | 7/31/2024 |
0.09833 % | CastleArk Management, LLC | 28,280 | -240 | 6/30/2024 |
0.09518 % | Canada Life Asset Management Limited | 27,373 | 24,245 | 6/30/2024 |
0.09362 % | Arctic Fund Management AS | 26,924 | -15,110 | 4/30/2024 |
0.09188 % | PGIM Quantitative Solutions LLC | 26,425 | 24,829 | 6/30/2024 |
0.09139 % | EAM Investors, LLC | 26,284 | -151 | 6/30/2024 |
0.08993 % | New York State Common Retirement Fund | 25,863 | -2,518 | 9/30/2024 |
0.08800 % | State of Wisconsin Investment Board | 25,310 | 9,095 | 6/30/2024 |
0.07743 % | Alps Advisors, Inc. | 22,270 | 22,270 | 6/30/2024 |