9.83088 % | Soleus Capital Management, L.P. | 6,978,942 | 374,946 | 12/31/2024 |
9.65311 % | Lynx1 Capital Advisors LLC | 6,852,744 | -27,783 | 12/31/2024 |
8.55416 % | Wasatch Global Investors Inc | 6,072,601 | 395,233 | 12/31/2024 |
7.84326 % | Betta investment Hong Kong Ltd | 5,567,928 | 5,567,928 | 1/4/2024 |
6.87521 % | BlackRock Institutional Trust Company, N.A. | 4,880,710 | 606,620 | 12/31/2024 |
6.87139 % | RA Capital Management, LP | 4,878,000 | 0 | 12/31/2024 |
6.16692 % | OrbiMed Advisors, LLC | 4,377,900 | 0 | 12/31/2024 |
4.71330 % | The Vanguard Group, Inc. | 3,345,973 | -24,708 | 12/31/2024 |
4.60588 % | Morgan Stanley & Co. LLC | 3,269,713 | 1,744,499 | 12/31/2024 |
4.25336 % | Samlyn Capital, LLC | 3,019,458 | 3,019,458 | 12/31/2024 |
2.36321 % | BofA Global Research (US) | 1,677,642 | -358,591 | 12/31/2024 |
2.18341 % | Adage Capital Management, L.P. | 1,550,000 | 1,030,000 | 12/31/2024 |
2.03992 % | Two Sigma Investments, LP | 1,448,137 | -445,853 | 12/31/2024 |
1.94547 % | Geode Capital Management, L.L.C. | 1,381,086 | 11,410 | 12/31/2024 |
1.87928 % | ArrowMark Colorado Holdings, LLC | 1,334,101 | 14,617 | 12/31/2024 |
1.72280 % | State Street Global Advisors (US) | 1,223,018 | -1,583,895 | 12/31/2024 |
1.72015 % | SilverArc Capital Management, LLC | 1,221,131 | 73,240 | 12/31/2024 |
1.56629 % | Bain Capital Life Sciences Investors, LLC | 1,111,910 | 0 | 12/31/2024 |
1.26778 % | Tang Capital Management, LLC | 900,000 | 200,000 | 12/31/2024 |
1.13211 % | Dubin (Glenn R.) | 803,682 | -7,642 | 4/23/2024 |
1.02708 % | UBS Financial Services, Inc. | 729,124 | 395,043 | 12/31/2024 |
0.78560 % | Morgan Stanley Investment Management Inc. (US) | 557,700 | -192,300 | 12/31/2024 |
0.73803 % | Dimensional Fund Advisors, L.P. | 523,931 | -54,954 | 12/31/2024 |
0.69587 % | Northern Trust Investments, Inc. | 494,000 | 42,242 | 12/31/2024 |
0.68959 % | Downey (Bruce L) | 489,542 | 0 | 4/23/2024 |
0.68512 % | Charles Schwab Investment Management, Inc. | 486,366 | 3,437 | 12/31/2024 |
0.64065 % | Goldman Sachs & Company, Inc. | 454,794 | 108,700 | 12/31/2024 |
0.62711 % | BlackRock Financial Management, Inc. | 445,185 | 37,739 | 12/31/2024 |
0.50729 % | Millennium Management LLC | 360,125 | 338,277 | 12/31/2024 |
0.45569 % | Anderson (Kenneth Carl) | 323,492 | 3,074 | 1/2/2025 |
0.39964 % | Wellington Management Company, LLP | 283,705 | -2,336 | 12/31/2024 |
0.32755 % | Fisher (Stewart) | 232,531 | 1,589 | 9/16/2024 |
0.31997 % | Hennion & Walsh Asset Management, Inc. | 227,147 | 34,783 | 12/31/2024 |
0.31253 % | Hirsch (Andrew) | 221,862 | 6,950 | 11/7/2024 |
0.30760 % | Fidelity Management & Research Company LLC | 218,365 | 32,424 | 12/31/2024 |
0.27675 % | Point72 Asset Management, L.P. | 196,466 | -1,005,382 | 12/31/2024 |
0.26108 % | BlackRock Investment Management, LLC | 185,344 | 6,688 | 12/31/2024 |
0.25476 % | Nuveen LLC | 180,853 | 0 | 12/31/2024 |
0.23662 % | Mariner Wealth Advisors | 167,975 | 37,564 | 12/31/2024 |
0.21834 % | Sio Capital Management, LLC | 155,000 | 155,000 | 12/31/2024 |
0.21520 % | Jane Street Capital, L.L.C. | 152,774 | 83,323 | 12/31/2024 |
0.19349 % | UBS O'Connor LLC | 137,360 | 114,360 | 12/31/2024 |
0.18711 % | American Century Investment Management, Inc. | 132,832 | 10,459 | 12/31/2024 |
0.18680 % | Wilmington Trust Investment Advisors, Inc. | 132,608 | 18,860 | 12/31/2024 |
0.17237 % | Barclays Bank PLC | 122,365 | -121,092 | 12/31/2024 |
0.16743 % | Goldman Sachs Asset Management, L.P. | 118,861 | -40,897 | 12/31/2024 |
0.16669 % | Wexford Capital LP | 118,331 | 63,100 | 12/31/2024 |
0.15470 % | Cubist Systematic Strategies, LLC | 109,825 | 6,799 | 12/31/2024 |
0.15307 % | Susquehanna Fundamental Investments, LLC | 108,664 | -21,137 | 12/31/2024 |
0.14324 % | Atom Investors LP | 101,684 | 101,684 | 12/31/2024 |
0.14172 % | Mackenzie Investments | 100,609 | 115 | 11/30/2024 |
0.14089 % | Rhumbline Advisers Ltd. Partnership | 100,015 | 4,366 | 12/31/2024 |
0.13615 % | BNY Mellon Asset Management | 96,652 | -4,173 | 12/31/2024 |
0.12933 % | Reyno (Leonard) | 91,809 | -6,191 | 7/10/2024 |
0.11974 % | Vienna Powszechne Towarzystwo Emerytalne SA Vienna Insurance Group | 85,000 | 0 | 12/31/2024 |
0.11894 % | Adams (Kendra) | 84,439 | 2,648 | 11/7/2024 |
0.11012 % | Goldman Sachs Asset Management International | 78,171 | 78,171 | 6/30/2024 |
0.11004 % | Avantis Investors | 78,118 | 50,963 | 3/31/2024 |
0.10818 % | Mahaney (Paige) | 76,800 | 76,800 | 10/28/2024 |
0.10773 % | D. E. Shaw & Co., L.P. | 76,479 | -42,413 | 12/31/2024 |
0.09906 % | LPL Financial LLC | 70,325 | 8,150 | 12/31/2024 |
0.09808 % | Verition Fund Management LLC | 69,628 | 69,628 | 12/31/2024 |
0.08403 % | ExodusPoint Capital Management, LP | 59,654 | 59,654 | 12/31/2024 |
0.08223 % | Citi Investment Research (US) | 58,376 | -45,592 | 12/31/2024 |
0.07968 % | Boyle (Scott N) | 56,567 | 2,648 | 11/7/2024 |
0.07957 % | Siegel (Jolie M.) | 56,488 | 2,648 | 11/7/2024 |
0.07957 % | Schick (Kelly) | 56,488 | 2,648 | 11/7/2024 |
0.07184 % | LMR Partners LLP | 51,000 | 0 | 12/31/2024 |
0.06733 % | AllianceBernstein L.P. | 47,800 | 0 | 12/31/2024 |
0.06259 % | Mellon Investments Corporation | 44,431 | 1,963 | 12/31/2024 |
0.06229 % | Susquehanna International Group, LLP | 44,223 | -5,884 | 12/31/2024 |
0.06009 % | Invesco Capital Management LLC | 42,660 | 2,451 | 12/31/2024 |
0.05991 % | Balyasny Asset Management LP | 42,533 | 22,789 | 12/31/2024 |
0.05750 % | Walleye Capital LLC | 40,819 | 40,819 | 12/31/2024 |
0.05635 % | Intrepid Family Office LLC | 40,000 | 40,000 | 12/31/2024 |
0.05373 % | T. Rowe Price International Ltd | 38,143 | -25,161 | 12/31/2024 |
0.05095 % | Marshall Wace LLP | 36,167 | -189,249 | 12/31/2024 |
0.05075 % | Mirae Asset Global Investments (USA) LLC | 36,027 | -1,810 | 12/31/2024 |
0.04973 % | Wells Fargo Bank, N.A. | 35,306 | 8,389 | 12/31/2024 |
0.04816 % | Franklin Advisers, Inc. | 34,192 | 0 | 12/31/2024 |
0.04815 % | BlackRock Advisors (UK) Limited | 34,180 | 230 | 1/31/2025 |
0.04782 % | BlackRock Asset Management Ireland Limited | 33,950 | 33,950 | 12/31/2024 |
0.04632 % | Group One Trading, L.P. | 32,883 | 32,883 | 12/31/2024 |
0.04606 % | Grogan (Donna Roy M.D.) | 32,699 | 3,757 | 1/2/2025 |
0.04604 % | White (Lauren) | 32,686 | 1,589 | 8/30/2023 |
0.04511 % | Harvest Fund Management Co., Ltd. | 32,025 | 32,025 | 6/30/2024 |
0.04317 % | ACCI Capital Investments SGIIC, SA | 30,649 | 30,649 | 11/30/2024 |
0.04247 % | INTECH Investment Management LLC | 30,150 | 3,024 | 12/31/2024 |
0.04213 % | Corebridge Financial Inc. | 29,905 | -1,445 | 12/31/2024 |
0.04068 % | Commonwealth Financial Network | 28,880 | -6,290 | 12/31/2024 |
0.04065 % | MetLife Investment Management, LLC | 28,854 | -6,601 | 12/31/2024 |
0.04047 % | UBS Switzerland AG | 28,728 | 28,728 | 12/31/2024 |
0.04031 % | Citadel Advisors LLC | 28,616 | -5,481 | 12/31/2024 |
0.03944 % | Farallon Capital Management, L.L.C. | 28,000 | 0 | 12/31/2024 |
0.03921 % | Assenagon Asset Management S.A. | 27,832 | 2,781 | 1/31/2025 |
0.03759 % | Vaughan Nelson Investment Management, L.P. | 26,684 | 26,684 | 9/30/2024 |
0.03738 % | Invesco Advisers, Inc. | 26,533 | 2,196 | 12/31/2024 |
0.03726 % | JPMorgan Private Bank (United States) | 26,451 | 993 | 12/31/2024 |
0.03662 % | Salter (Malcolm) | 26,000 | 14,620 | 4/23/2024 |
0.03600 % | Engineers Gate Manager, L.P. | 25,555 | 2,742 | 12/31/2024 |