10,03904 % | Bain Capital Life Sciences Investors, LLC | 16 915 784 | 955 196 | 31.12.2023 |
8,89424 % | New Enterprise Associates (NEA) | 14 986 793 | 0 | 31.12.2023 |
4,75304 % | The Vanguard Group, Inc. | 8 008 865 | 184 148 | 31.12.2023 |
4,61187 % | BlackRock Institutional Trust Company, N.A. | 7 771 007 | 260 683 | 31.12.2023 |
4,23354 % | OrbiMed Advisors, LLC | 7 133 515 | 0 | 31.12.2023 |
2,53787 % | Adage Capital Management, L.P. | 4 276 315 | 0 | 31.12.2023 |
2,12963 % | Sio Capital Management, LLC | 3 588 427 | 989 424 | 31.12.2023 |
2,10413 % | Perceptive Advisors LLC | 3 545 454 | 0 | 31.12.2023 |
2,06153 % | Kingdon Capital Management, L.L.C. | 3 473 683 | 1 500 000 | 31.12.2023 |
1,82405 % | AXA Investment Managers UK Ltd. | 3 073 532 | -74 333 | 31.12.2023 |
1,80800 % | Acorn Bioventures L.P. | 3 046 472 | 0 | 31.12.2023 |
1,66317 % | Geode Capital Management, L.L.C. | 2 802 449 | 159 534 | 31.12.2023 |
1,63578 % | Medical Strategy GmbH | 2 756 296 | 0 | 31.12.2023 |
1,44082 % | State Street Global Advisors (US) | 2 427 789 | 49 163 | 31.12.2023 |
1,14896 % | Armistice Capital LLC | 1 936 000 | -420 000 | 31.12.2023 |
1,03444 % | UBS O'Connor LLC | 1 743 038 | 183 052 | 31.12.2023 |
1,02556 % | Citadel Advisors LLC | 1 728 065 | -70 563 | 31.12.2023 |
0,98773 % | Millennium Management LLC | 1 664 317 | -1 951 647 | 31.12.2023 |
0,57351 % | Northern Trust Investments, Inc. | 966 363 | 4 792 | 31.12.2023 |
0,56093 % | GSA Capital Partners LLP | 945 171 | 323 584 | 31.12.2023 |
0,45539 % | Parkman Healthcare Partners LLC | 767 332 | -32 668 | 31.12.2023 |
0,38576 % | Point72 Asset Management, L.P. | 650 000 | 0 | 31.12.2023 |
0,35992 % | Ragan (Paula) | 606 464 | -49 678 | 11.03.2024 |
0,32599 % | Schonfeld Strategic Advisors LLC | 549 300 | -36 742 | 31.12.2023 |
0,31751 % | Propel Bio Management, LLC | 535 000 | 135 000 | 31.12.2023 |
0,31430 % | Barclays Bank PLC | 529 601 | 147 467 | 31.12.2023 |
0,26001 % | Nuveen LLC | 438 114 | 0 | 31.12.2023 |
0,23912 % | Susquehanna International Group, LLP | 402 921 | 297 714 | 31.12.2023 |
0,23739 % | Simplify Asset Management Inc | 400 000 | 0 | 31.12.2023 |
0,23048 % | Royce Investment Partners | 388 363 | 269 357 | 31.12.2023 |
0,20846 % | BlackRock Investment Management, LLC | 351 262 | 0 | 31.12.2023 |
0,20605 % | Morgan Stanley & Co. LLC | 347 188 | 275 251 | 31.12.2023 |
0,19881 % | New Leaf Venture Partners LLC | 335 000 | 0 | 31.12.2023 |
0,19219 % | Charles Schwab Investment Management, Inc. | 323 843 | 0 | 31.12.2023 |
0,18486 % | SV Health Investors, LLC | 311 490 | 0 | 30.09.2022 |
0,17523 % | BlackRock Financial Management, Inc. | 295 255 | 0 | 31.12.2023 |
0,17477 % | BNY Mellon Asset Management | 294 492 | -128 739 | 31.12.2023 |
0,16828 % | BNP Paribas Securities Corp. North America | 283 544 | 236 899 | 31.12.2023 |
0,13905 % | Taveras (Arthur PhD) | 234 301 | -14 235 | 11.03.2024 |
0,13531 % | Mostafa (Adam S.) | 228 004 | 222 587 | 31.10.2023 |
0,12634 % | BofA Global Research (US) | 212 888 | -160 305 | 31.12.2023 |
0,12292 % | Dibiase (Mary) | 207 128 | -15 409 | 11.03.2024 |
0,10778 % | Acadian Asset Management LLC | 181 609 | 181 609 | 31.12.2023 |
0,09753 % | AQR Capital Management, LLC | 164 342 | 103 053 | 31.12.2023 |
0,09518 % | Rhumbline Advisers Ltd. Partnership | 160 370 | 0 | 31.12.2023 |
0,08497 % | Stewart (Murray) | 143 170 | 139 837 | 10.08.2023 |
0,07672 % | Jane Street Capital, L.L.C. | 129 274 | 115 907 | 31.12.2023 |
0,07580 % | Virtu Americas LLC | 127 718 | 127 718 | 31.12.2023 |
0,07080 % | Knott Partners Management, LLC | 119 300 | 119 300 | 31.12.2023 |
0,05734 % | Northern Trust Global Investments | 96 622 | -9 500 | 31.12.2023 |
0,05368 % | Stifel, Nicolaus & Company, Incorporated | 90 452 | 10 174 | 31.12.2023 |
0,05341 % | Woods (Keith) | 90 000 | 90 000 | 16.10.2023 |
0,04825 % | Amundi Asset Management, SAS | 81 305 | 0 | 31.12.2023 |
0,04736 % | JPMorgan Private Bank (United States) | 79 805 | 79 805 | 31.12.2023 |
0,04352 % | Wyzga (Michael S) | 73 333 | 25 000 | 18.08.2023 |
0,04200 % | Group One Trading, L.P. | 70 764 | -155 597 | 31.12.2023 |
0,04100 % | XTX Markets LLC | 69 086 | 69 086 | 31.12.2023 |
0,03844 % | Squarepoint Capital LLP | 64 763 | 64 763 | 31.12.2023 |
0,03632 % | SunAmerica Asset Management, LLC | 61 198 | -247 | 31.12.2023 |
0,03282 % | Dimensional Fund Advisors, L.P. | 55 296 | 0 | 31.12.2023 |
0,03243 % | Invesco Advisers, Inc. | 54 649 | 1 620 | 31.12.2023 |
0,03159 % | Morgan Stanley Smith Barney LLC | 53 235 | 10 800 | 31.12.2023 |
0,03059 % | New York State Common Retirement Fund | 51 551 | -417 | 31.12.2023 |
0,03054 % | Mellon Investments Corporation | 51 462 | 0 | 31.12.2023 |
0,02923 % | Voya Investment Management LLC | 49 260 | 0 | 31.12.2023 |
0,02868 % | Aliski (William) | 48 333 | 45 000 | 13.06.2023 |
0,02868 % | Lawton (Alison Frances) | 48 333 | 45 000 | 13.06.2023 |
0,02868 % | Bridger (Gary J) | 48 333 | 45 000 | 13.06.2023 |
0,02868 % | McGirr (David W J) | 48 333 | 45 000 | 13.06.2023 |
0,02868 % | de (Craecker Francoise) | 48 333 | 45 000 | 13.06.2023 |
0,02829 % | SG Americas Securities, L.L.C. | 47 668 | 13 328 | 31.12.2023 |
0,02754 % | Goldman Sachs & Company, Inc. | 46 404 | 26 689 | 31.12.2023 |
0,02711 % | AllianceBernstein L.P. | 45 680 | 0 | 31.12.2023 |
0,02671 % | Bank Vontobel AG | 45 000 | 0 | 31.12.2023 |
0,02671 % | CIBC Private Wealth Management | 45 000 | 0 | 31.12.2023 |
0,02479 % | Invesco Capital Management LLC | 41 777 | 13 777 | 31.12.2023 |
0,02338 % | Bayesian Capital Management, LP | 39 400 | 39 400 | 31.12.2023 |
0,02079 % | Wells Fargo Bank, N.A. | 35 024 | 7 396 | 31.12.2023 |
0,01898 % | Florida State Board of Administration | 31 979 | 31 979 | 31.12.2023 |
0,01790 % | PNC Investments LLC | 30 158 | -192 | 31.12.2023 |
0,01758 % | Walleye Capital LLC | 29 616 | 29 616 | 31.12.2023 |
0,01590 % | T. Rowe Price International Ltd | 26 793 | 0 | 31.12.2023 |
0,01566 % | Goldman Sachs Asset Management, L.P. | 26 384 | -3 494 | 31.12.2023 |
0,01559 % | RBC Wealth Management, International | 26 264 | 8 221 | 31.12.2023 |
0,01531 % | OneDigital Investment Advisors LLC | 25 801 | -4 514 | 31.12.2023 |
0,01490 % | Commonwealth Financial Network | 25 100 | -1 650 | 31.12.2023 |
0,01473 % | Vaughan Nelson Investment Management, L.P. | 24 819 | 0 | 31.12.2023 |
0,01465 % | Baldry (Mark) | 24 690 | -10 257 | 01.11.2023 |
0,01294 % | Private Advisor Group LLC | 21 800 | 0 | 31.12.2023 |
0,01209 % | ProShare Advisors LLC | 20 378 | 4 383 | 31.12.2023 |
0,01203 % | California State Teachers Retirement System | 20 265 | -6 902 | 31.12.2023 |
0,01060 % | Bleichroeder LP | 17 865 | 0 | 31.12.2023 |
0,01046 % | Citi Investment Research (US) | 17 630 | 17 562 | 31.12.2023 |
0,01014 % | HRT Financial LP | 17 084 | 17 084 | 31.12.2023 |
0,01014 % | Victory Capital Management Inc. | 17 079 | 3 348 | 31.12.2023 |
0,00987 % | Principal Global Investors (Equity) | 16 626 | 299 | 31.12.2023 |
0,00950 % | Lexaurum Advisors, LLC | 16 000 | 0 | 31.03.2024 |
0,00890 % | Grimes & Company, Inc. | 15 000 | 0 | 31.03.2024 |
0,00836 % | Amalgamated Bank Institutional Asset Management & Custody | 14 086 | -1 235 | 31.12.2023 |
0,00790 % | Mackenzie Financial Corporation | 13 316 | -50 | 31.12.2023 |