17,75991 % | RA Capital Management, LP | 10 281 496 | 0 | 30.06.2025 |
9,41657 % | Westfield Capital Management Company, L.P. | 5 451 401 | -27 858 | 30.06.2025 |
8,60228 % | Avoro Capital Advisors LLC | 4 980 000 | -238 000 | 30.06.2025 |
7,64842 % | Janus Henderson Investors | 4 427 792 | -59 157 | 30.06.2025 |
7,21886 % | Fidelity Management & Research Company LLC | 4 179 114 | -125 413 | 30.06.2025 |
6,89292 % | Artisan Partners Limited Partnership | 3 990 424 | -266 203 | 30.06.2025 |
6,19010 % | T. Rowe Price Investment Management, Inc. | 3 583 546 | 529 722 | 30.06.2025 |
5,26317 % | Capital International Investors | 3 046 931 | 172 139 | 30.06.2025 |
3,27753 % | MFS Investment Management | 1 897 414 | 23 616 | 30.06.2025 |
3,23966 % | T. Rowe Price Associates, Inc. | 1 875 491 | -380 611 | 30.06.2025 |
2,36925 % | Capital World Investors | 1 371 594 | 16 613 | 31.07.2025 |
2,16018 % | Franklin Advisers, Inc. | 1 250 562 | 177 646 | 30.06.2025 |
1,66498 % | Perceptive Advisors LLC | 963 886 | 963 886 | 30.06.2025 |
1,58589 % | Wellington Management Company, LLP | 918 095 | 330 332 | 30.06.2025 |
1,56219 % | Invesco Advisers, Inc. | 904 374 | -246 458 | 30.06.2025 |
1,44715 % | Polar Capital LLP | 837 777 | 312 777 | 30.06.2025 |
1,01581 % | Columbia Threadneedle Investments (US) | 588 069 | -91 874 | 30.06.2025 |
1,01455 % | Citadel Advisors LLC | 587 342 | -537 841 | 30.06.2025 |
0,91690 % | American Century Investment Management, Inc. | 530 809 | 68 638 | 30.06.2025 |
0,88398 % | Medical Strategy GmbH | 511 748 | 38 500 | 30.11.2024 |
0,85985 % | Putnam Investment Management, L.L.C. | 497 779 | -63 999 | 30.06.2025 |
0,83525 % | Goldman Sachs & Company, Inc. | 483 539 | -53 509 | 30.06.2025 |
0,80166 % | Fidelity International | 464 096 | 1 730 | 30.06.2025 |
0,79391 % | Adage Capital Management, L.P. | 459 606 | 132 201 | 30.06.2025 |
0,75702 % | Mikkelsen Jan Moller | 438 250 | 14 971 | 31.12.2024 |
0,65243 % | AllianceBernstein L.P. | 377 701 | -54 397 | 30.06.2025 |
0,60909 % | Fidelity Institutional Asset Management | 352 610 | -15 806 | 30.06.2025 |
0,52763 % | Woodline Partners LP | 305 454 | 648 | 30.06.2025 |
0,50455 % | TD Asset Management Inc. | 292 090 | -51 300 | 30.06.2025 |
0,47845 % | BNP Paribas Asset Management USA, Inc. | 276 984 | -53 169 | 30.06.2025 |
0,45476 % | Voloridge Investment Management, LLC | 263 267 | -82 751 | 30.06.2025 |
0,44048 % | Q Global Advisors, LLC | 255 000 | 6 113 | 30.06.2025 |
0,43243 % | The Vanguard Group, Inc. | 250 342 | 0 | 30.06.2025 |
0,43184 % | Camber Capital Management LP | 250 000 | -100 000 | 30.06.2025 |
0,42483 % | Invus Public Equities Advisors, LLC | 245 943 | -41 423 | 30.06.2025 |
0,42043 % | BlackRock Institutional Trust Company, N.A. | 243 396 | -28 469 | 30.06.2025 |
0,40864 % | SEI Investments Management Corporation | 236 570 | -21 443 | 30.06.2025 |
0,38305 % | PFM Health Sciences, LP | 221 754 | 34 838 | 30.06.2025 |
0,37850 % | Victory Capital Management Inc. | 219 118 | 94 192 | 30.06.2025 |
0,37484 % | Rock Springs Capital Management LP | 217 000 | 1 000 | 30.06.2025 |
0,37132 % | Candriam Luxembourg S.A. | 214 963 | 0 | 30.06.2025 |
0,36263 % | ARS Investment Partners LLC | 209 930 | -55 550 | 30.06.2025 |
0,34728 % | Qube Research & Technologies Ltd | 201 044 | 91 412 | 30.06.2025 |
0,34592 % | Allspring Global Investments, LLC | 200 257 | 10 644 | 30.06.2025 |
0,34547 % | Vestal Point Capital, LP | 200 000 | 49 858 | 30.06.2025 |
0,33704 % | Candriam Belgium S.A. | 195 115 | -47 646 | 30.06.2025 |
0,33702 % | Driehaus Capital Management, LLC | 195 108 | 43 279 | 30.06.2025 |
0,32540 % | Morgan Stanley & Co. LLC | 188 379 | -1 676 305 | 30.06.2025 |
0,31534 % | New York State Common Retirement Fund | 182 558 | -21 924 | 30.06.2025 |
0,31080 % | Catalio Capital Management, LP | 179 926 | -15 597 | 30.06.2025 |
0,28617 % | BNP Paribas Securities Corp. North America | 165 667 | 23 043 | 30.06.2025 |
0,28279 % | BlackRock Financial Management, Inc. | 163 711 | -18 147 | 30.06.2025 |
0,27754 % | Resolute Capital Asset Partners LLC | 160 672 | -6 828 | 30.06.2025 |
0,27657 % | Rice Hall James & Associates, LLC | 160 110 | -686 | 30.06.2025 |
0,27466 % | JPMorgan Asset Management U.K. Limited | 159 007 | 3 053 | 30.06.2025 |
0,27466 % | JPMorgan Asset Management (Europe) S.à.r.l. | 159 007 | -1 152 | 30.06.2025 |
0,26632 % | Lord, Abbett & Co. LLC | 154 176 | 94 781 | 30.06.2025 |
0,25791 % | Pictet Asset Management (Japan) Ltd. | 149 310 | 18 559 | 31.10.2024 |
0,25651 % | Loomis, Sayles & Company, L.P. | 148 497 | -26 416 | 30.06.2025 |
0,25503 % | Tri Locum Partners LP | 147 642 | 115 317 | 30.06.2025 |
0,24115 % | abrdn Inc. | 139 606 | -32 125 | 30.06.2025 |
0,23265 % | First Turn Management, LLC | 134 687 | 21 409 | 30.06.2025 |
0,23031 % | Frazier Life Sciences Management, L.P. | 133 333 | 0 | 30.06.2025 |
0,22456 % | Summit Partners Public Asset Management, LLC | 130 000 | 130 000 | 30.06.2025 |
0,20728 % | Moore Capital Management, LP | 120 000 | 30 000 | 30.06.2025 |
0,20238 % | Marshall Wace LLP | 117 162 | 94 868 | 30.06.2025 |
0,20164 % | Macquarie Investment Management | 116 735 | 47 712 | 30.06.2025 |
0,17432 % | Readystate Asset Management LP | 100 917 | 100 917 | 30.06.2025 |
0,14951 % | SilverArc Capital Management, LLC | 86 552 | 10 801 | 30.06.2025 |
0,14776 % | Pictet Asset Management Ltd. | 85 538 | -21 220 | 30.06.2025 |
0,14683 % | Soleus Capital Management, L.P. | 85 000 | 28 700 | 30.06.2025 |
0,14296 % | UBS Financial Services, Inc. | 82 760 | -91 081 | 30.06.2025 |
0,14048 % | BofA Global Research (US) | 81 325 | -43 503 | 30.06.2025 |
0,14039 % | Norges Bank Investment Management (NBIM) | 81 276 | -82 014 | 31.12.2024 |
0,13570 % | Harbor Capital Advisors, Inc. | 78 560 | -7 400 | 30.06.2025 |
0,12590 % | Millennium Management LLC | 72 888 | -191 979 | 30.06.2025 |
0,12554 % | Dafna Capital Management, LLC | 72 677 | -7 721 | 30.06.2025 |
0,12144 % | Mellon Investments Corporation | 70 303 | 16 855 | 30.06.2025 |
0,11078 % | Trexquant Investment LP | 64 135 | 20 375 | 30.06.2025 |
0,10977 % | Oddo BHF Asset Management S.A.S | 63 547 | 63 547 | 30.06.2025 |
0,10662 % | Ensign Peak Advisors, Inc. | 61 724 | 0 | 30.06.2025 |
0,10503 % | Geode Capital Management, L.L.C. | 60 804 | 2 953 | 30.06.2025 |
0,10062 % | Manulife Investment Management (North America) Limited | 58 251 | -20 881 | 30.06.2025 |
0,10054 % | State Street Global Advisors (US) | 58 203 | -8 576 | 30.06.2025 |
0,09859 % | AEGON Investment Management B.V. | 57 076 | 2 920 | 31.01.2024 |
0,09844 % | Schroder Investment Management Ltd. (SIM) | 56 989 | -47 928 | 30.06.2025 |
0,09416 % | Sterling Capital Management, LLC | 54 509 | 3 432 | 30.06.2025 |
0,09225 % | Goldman Sachs Asset Management, L.P. | 53 407 | 4 874 | 30.06.2025 |
0,09091 % | Lazard Asset Management, L.L.C. | 52 628 | 9 505 | 30.06.2025 |
0,07845 % | Diversified Trust Company | 45 418 | -1 130 | 30.06.2025 |
0,07805 % | J.P. Morgan Securities LLC | 45 182 | 20 984 | 30.06.2025 |
0,07274 % | Parkman Healthcare Partners LLC | 42 108 | 42 108 | 30.06.2025 |
0,06979 % | Walleye Capital LLC | 40 403 | 24 566 | 30.06.2025 |
0,06961 % | Zimmer Partners, LP | 40 300 | 4 200 | 30.06.2025 |
0,06944 % | International Asset Management Limited | 40 200 | -15 197 | 30.04.2025 |
0,06597 % | Saturn V Capital Management LP | 38 191 | -161 073 | 30.06.2025 |
0,06224 % | BlackRock Advisors (UK) Limited | 36 031 | 5 754 | 31.07.2025 |
0,06208 % | Thrivent Asset Management, LLC | 35 941 | -42 532 | 31.12.2024 |
0,05989 % | Macquarie Investment Management Global Ltd. | 34 672 | 0 | 30.06.2025 |
0,05942 % | OrbiMed Advisors, LLC | 34 400 | 34 400 | 30.06.2025 |