16,36437 % | Sofinnova Investments, Inc | 3 606 707 | 0 | 2021-12-31 |
13,59283 % | VenBio Partners LLC | 2 995 859 | −677 515 | 2022-04-26 |
9,80939 % | Novo Holdings A/S | 2 161 990 | −8 110 | 2022-02-25 |
8,14279 % | Longitude Capital Management Co., LLC | 1 794 671 | 1 794 671 | 2020-08-11 |
6,81359 % | Medicxi Ventures (UK) LLP | 1 501 716 | 0 | 2021-12-31 |
6,05740 % | Omega Fund Management, LLC | 1 335 050 | 0 | 2021-12-31 |
6,04925 % | Decheng Capital China Life Sciences USD Fund I, L.P. | 1 333 254 | −100 | 2021-12-31 |
5,92843 % | Clough Capital Partners, LP | 1 306 626 | −260 700 | 2021-12-31 |
4,63296 % | Krieg (Arthur M) | 1 021 105 | 10 802 | 2021-06-18 |
4,38850 % | Fidelity Management & Research Company LLC | 967 226 | 1 000 | 2021-12-31 |
2,63095 % | The Vanguard Group, Inc. | 579 861 | 243 274 | 2021-12-31 |
2,45810 % | Sectoral Asset Management Inc. | 541 766 | 0 | 2021-12-31 |
0,48321 % | Bridgeway Capital Management, LLC | 106 500 | 0 | 2021-12-31 |
0,42348 % | Ensign Peak Advisors, Inc. | 93 334 | −26 581 | 2021-12-31 |
0,30868 % | RBF Capital, LLC | 68 034 | −800 | 2021-12-31 |
0,18267 % | Geode Capital Management, L.L.C. | 40 260 | 0 | 2021-12-31 |
0,13862 % | BlackRock Institutional Trust Company, N.A. | 30 551 | 575 | 2021-12-31 |
0,13612 % | Federated Hermes Equity Management Company of Pennsylvania | 30 000 | 10 000 | 2021-12-31 |
0,11166 % | Cambridge Trust Company | 24 609 | 0 | 2021-12-31 |
0,08819 % | BlackRock Financial Management, Inc. | 19 437 | 0 | 2021-12-31 |
0,05030 % | State Street Global Advisors (US) | 11 087 | 0 | 2021-12-31 |
0,04824 % | Millennium Management LLC | 10 633 | 10 633 | 2021-12-31 |
0,03630 % | Chaudhary (Kleem) | 8 000 | 0 | 2021-04-23 |
0,01849 % | Morgan Stanley & Co. LLC | 4 075 | 1 | 2021-12-31 |
0,00907 % | U.S. Bancorp Asset Management, Inc. | 2 000 | 0 | 2021-12-31 |
0,00819 % | BlackRock Investment Management, LLC | 1 806 | 0 | 2021-12-31 |
0,00819 % | Lord, Abbett & Co. LLC | 1 806 | 0 | 2022-02-28 |
0,00538 % | Manulife Investment Management (North America) Limited | 1 186 | 0 | 2022-02-28 |
0,00505 % | BofA Global Research (US) | 1 112 | −2 258 | 2021-12-31 |
0,00501 % | UBS Financial Services, Inc. | 1 105 | 922 | 2021-12-31 |
0,00261 % | BlackRock Japan Co., Ltd. | 575 | 0 | 2021-12-31 |
0,00091 % | Midwest Financial | 200 | 0 | 2022-03-31 |
0,00076 % | RBC Capital Partners | 168 | 0 | 2021-12-31 |
0,00042 % | Federated Hermes MDTA LLC | 92 | 92 | 2021-12-31 |
0,00015 % | Wells Fargo Bank, N.A. | 33 | 0 | 2021-12-31 |
0 % | Ergoteles Capital | 0 | −25 870 | 2021-12-31 |
0 % | HRT Financial LP | 0 | −18 298 | 2021-12-31 |
0 % | Advisory Services Network, LLC | 0 | −7 800 | 2021-09-30 |
0 % | Zimmer Partners, LP | 0 | −25 000 | 2020-12-31 |
0 % | BMO Nesbitt Burns Inc. | 0 | −280 | 2021-06-30 |
0 % | Principal Funds, Inc. | 0 | −1 478 | 2021-06-30 |
0 % | DWS Investments UK Limited | 0 | −5 639 | 2021-06-30 |
0 % | Assenagon Asset Management S.A. | 0 | −199 | 2021-06-30 |
0 % | Pacific Asset Management | 0 | −1 100 | 2021-06-30 |
0 % | ProShare Advisors LLC | 0 | −2 494 | 2021-06-30 |
0 % | Laurie J. Hall Trustee | 0 | −100 530 | 2021-03-31 |
0 % | Tower Research Capital LLC | 0 | −1 426 | 2021-12-31 |
0 % | Northern Trust Global Investments | 0 | −8 015 | 2021-06-30 |
0 % | DNCA Investments | 0 | −71 261 | 2021-12-31 |
0 % | CPP Investment Board | 0 | −10 000 | 2021-06-30 |
0 % | Morgan Stanley & Co. International Plc | 0 | −46 | 2021-12-31 |
0 % | ProFund Advisors LLC | 0 | −194 | 2021-07-31 |
0 % | Renaissance Technologies LLC | 0 | −10 667 | 2021-12-31 |
0 % | Moore Capital Management, LP | 0 | −10 000 | 2020-12-31 |
0 % | PGIM Quantitative Solutions LLC | 0 | −1 554 | 2021-04-30 |
0 % | Charles Schwab Investment Management, Inc. | 0 | −19 146 | 2021-06-30 |
0 % | Legal & General Investment Management Ltd. | 0 | −876 | 2021-06-30 |
0 % | DWS Investment GmbH | 0 | −134 760 | 2021-09-30 |
0 % | Vaughan Nelson Investment Management, L.P. | 0 | −290 | 2021-06-30 |
0 % | Citi Investment Research (US) | 0 | −1 | 2021-09-30 |
0 % | AXA Rosenberg Investment Management LLC | 0 | −2 371 | 2021-06-30 |
0 % | PNC Wealth Management | 0 | −5 000 | 2021-12-31 |
0 % | T. Rowe Price Associates, Inc. | 0 | −145 | 2021-06-30 |
0 % | State Teachers Retirement System of Ohio | 0 | −19 300 | 2021-06-30 |
0 % | Morgan Stanley Investment Management Inc. (US) | 0 | −77 | 2021-09-30 |
0 % | SunAmerica Asset Management, LLC | 0 | −5 217 | 2021-06-30 |
0 % | Goldman Sachs & Company, Inc. | 0 | −12 600 | 2020-12-31 |
0 % | Nuveen LLC | 0 | −16 328 | 2021-06-30 |
0 % | JPMorgan Private Bank (United States) | 0 | −3 531 | 2021-06-30 |
0 % | Ameritas Investment Partners, Inc. | 0 | −430 | 2021-06-30 |
0 % | BNY Mellon Asset Management | 0 | −15 196 | 2021-06-30 |
0 % | Northern Trust Investments, Inc. | 0 | −73 344 | 2021-06-30 |
0 % | Jacobs Levy Equity Management, Inc. | 0 | −36 511 | 2021-12-31 |
0 % | Federated Hermes Global Investment Management Corp. | 0 | −10 781 | 2021-06-30 |
0 % | BMO Capital Markets (US) | 0 | −328 | 2021-06-30 |
0 % | Westfield Capital Management Company, L.P. | 0 | −77 | 2021-06-30 |
0 % | J.P. Morgan Securities LLC | 0 | −185 | 2021-12-31 |
0 % | Alberta Investment Management Corporation | 0 | −25 000 | 2021-09-30 |
0 % | New York State Common Retirement Fund | 0 | −77 | 2021-09-30 |
0 % | California State Teachers Retirement System | 0 | −13 503 | 2021-06-30 |
0 % | Mellon Investments Corporation | 0 | −1 992 | 2021-06-30 |
0 % | Franklin Mutual Advisers, LLC | 0 | −398 | 2021-06-30 |
0 % | Voya Investment Management LLC | 0 | −4 304 | 2021-06-30 |
0 % | CaaS Capital Management LP | 0 | −44 966 | 2020-12-31 |