11,60734 % | Celgene Corporation | 7 008 510 | 183 825 | 2020-07-09 |
8,88561 % | T. Rowe Price Associates, Inc. | 5 365 133 | 65 321 | 2021-09-30 |
8,15699 % | The Vanguard Group, Inc. | 4 925 189 | 14 836 | 2021-09-30 |
6,62471 % | Avoro Capital Advisors LLC | 4 000 000 | 1 000 000 | 2021-09-30 |
3,94211 % | BlackRock Institutional Trust Company, N.A. | 2 380 249 | −19 835 | 2021-09-30 |
3,58507 % | Farallon Capital Management, L.L.C. | 2 164 663 | −335 337 | 2021-09-30 |
3,31236 % | Darwin Global Management Ltd | 2 000 000 | 239 654 | 2021-09-30 |
3,24598 % | Fidelity Management & Research Company LLC | 1 959 920 | −677 678 | 2021-09-30 |
2,63887 % | Janus Henderson Investors | 1 593 352 | −208 470 | 2021-09-30 |
2,14143 % | Baron Capital Management, Inc. | 1 292 998 | −9 277 | 2021-09-30 |
1,96044 % | State Street Global Advisors (US) | 1 183 716 | 77 846 | 2021-09-30 |
1,74159 % | Alkeon Capital Management LLC | 1 051 571 | −2 719 | 2021-09-30 |
1,73899 % | Pentwater Capital Management LP | 1 050 000 | 1 050 000 | 2021-09-30 |
1,69135 % | BlackRock Financial Management, Inc. | 1 021 239 | −246 946 | 2021-09-30 |
1,65618 % | Invus Public Equities Advisors, LLC | 1 000 000 | −400 000 | 2021-09-30 |
1,48211 % | Westfield Capital Management Company, L.P. | 894 898 | 39 254 | 2021-09-30 |
1,37738 % | Magnetar Capital Partners LP | 831 663 | 831 663 | 2021-09-30 |
1,23731 % | Holocene Advisors, LP | 747 086 | −123 138 | 2021-09-30 |
1,18470 % | Wellington Management Company, LLP | 715 322 | −1 010 633 | 2021-09-30 |
1,11732 % | Geode Capital Management, L.L.C. | 674 636 | 4 815 | 2021-09-30 |
0,92753 % | Lord, Abbett & Co. LLC | 560 040 | 108 953 | 2021-09-30 |
0,79108 % | Norges Bank Investment Management (NBIM) | 477 655 | 0 | 2020-12-31 |
0,78904 % | Assenagon Asset Management S.A. | 476 423 | −97 379 | 2021-09-30 |
0,78250 % | Brown Advisory | 472 473 | 9 370 | 2021-09-30 |
0,76555 % | Candriam Belgium S.A. | 462 239 | −94 816 | 2021-09-30 |
0,75700 % | Eagle Asset Management, Inc. | 457 077 | −3 176 | 2021-09-30 |
0,71479 % | BlackRock Investment Management (UK) Ltd. | 431 591 | −147 243 | 2021-09-30 |
0,71383 % | Fiera Capital Corporation | 431 009 | −6 624 | 2021-09-30 |
0,70600 % | Artisan Partners Limited Partnership | 426 285 | −525 825 | 2021-09-30 |
0,67317 % | Charles Schwab Investment Management, Inc. | 406 459 | 15 493 | 2021-09-30 |
0,66447 % | ARP Americas LP | 401 208 | 401 208 | 2021-09-30 |
0,66167 % | Franklin Advisers, Inc. | 399 517 | −15 697 | 2021-09-30 |
0,65252 % | Invesco Advisers, Inc. | 393 993 | −50 505 | 2021-09-30 |
0,65005 % | TimesSquare Capital Management, LLC | 392 500 | −122 495 | 2021-09-30 |
0,64672 % | Polar Capital LLP | 390 488 | −56 692 | 2021-09-30 |
0,63632 % | Susquehanna International Group, LLP | 384 210 | 358 022 | 2021-09-30 |
0,61157 % | Goldman Sachs & Company, Inc. | 369 268 | 298 968 | 2021-09-30 |
0,58678 % | Alpine Associates Management Inc. | 354 300 | 354 300 | 2021-09-30 |
0,57882 % | Eversept Partners, LP | 349 494 | 14 449 | 2021-09-30 |
0,45300 % | Millennium Management LLC | 273 520 | 261 193 | 2021-09-30 |
0,44931 % | D. E. Shaw & Co., L.P. | 271 291 | 201 795 | 2021-09-30 |
0,41200 % | Citi Investment Research (US) | 248 768 | 198 437 | 2021-09-30 |
0,36685 % | Carmignac Gestion | 221 502 | −236 764 | 2021-09-30 |
0,35606 % | Northern Trust Investments, Inc. | 214 988 | −6 428 | 2021-09-30 |
0,33983 % | Nuveen LLC | 205 187 | −47 128 | 2021-09-30 |
0,33202 % | New York State Common Retirement Fund | 200 476 | −88 110 | 2021-09-30 |
0,33124 % | NWI Management LP | 200 000 | 0 | 2021-09-30 |
0,33027 % | Oppenheimer Asset Management Inc. | 199 417 | −324 | 2021-09-30 |
0,31216 % | UBS Asset Management (Switzerland) | 188 483 | 7 531 | 2021-09-30 |
0,28950 % | Principal Global Investors (Equity) | 174 802 | −41 687 | 2021-09-30 |
0,28754 % | Foresite Capital Management, LLC | 173 614 | 0 | 2021-09-30 |
0,26420 % | Handelsbanken Asset Management | 159 523 | 11 000 | 2021-09-30 |
0,26150 % | TD Asset Management Inc. | 157 892 | 15 151 | 2021-09-30 |
0,24090 % | AllianceBernstein L.P. | 145 454 | 117 313 | 2021-09-30 |
0,24015 % | Deerfield Management Company, L.P. | 145 000 | −74 500 | 2021-09-30 |
0,23268 % | Balyasny Asset Management LP | 140 492 | 140 492 | 2021-09-30 |
0,22457 % | Dimensional Fund Advisors, L.P. | 135 593 | 1 914 | 2021-09-30 |
0,22298 % | Martingale Asset Management, L.P. | 134 635 | −25 713 | 2021-09-30 |
0,21436 % | Westchester Capital Management, LLC | 129 432 | 129 432 | 2021-09-30 |
0,20670 % | Ensign Peak Advisors, Inc. | 124 807 | −15 141 | 2021-09-30 |
0,19990 % | Schweizerische Nationalbank | 120 700 | 600 | 2021-09-30 |
0,18750 % | Morgan Stanley & Co. LLC | 113 213 | 51 757 | 2021-09-30 |
0,18684 % | Fidelity Institutional Asset Management | 112 815 | −53 526 | 2021-09-30 |
0,18331 % | Russell Investments Trust Company | 110 683 | 23 523 | 2021-09-30 |
0,17855 % | BNP Paribas Asset Management USA, Inc. | 107 808 | −75 566 | 2021-09-30 |
0,17789 % | California Public Employees' Retirement System | 107 408 | −899 | 2021-09-30 |
0,17738 % | UBS Financial Services, Inc. | 107 102 | 30 818 | 2021-09-30 |
0,17638 % | Gabelli Funds, LLC | 106 500 | 106 500 | 2021-09-30 |
0,17124 % | Voloridge Investment Management, LLC | 103 394 | 103 394 | 2021-09-30 |
0,17072 % | Mellon Investments Corporation | 103 082 | −299 816 | 2021-09-30 |
0,16995 % | Parallax Volatility Advisers, L.P. | 102 614 | 102 614 | 2021-09-30 |
0,16380 % | Nomura Asset Management Co., Ltd. | 98 900 | 98 900 | 2020-11-30 |
0,15635 % | Loomis, Sayles & Company, L.P. | 94 406 | 94 406 | 2021-09-30 |
0,15204 % | Atika Capital Management LLC | 91 800 | 1 700 | 2021-09-30 |
0,15034 % | California State Teachers Retirement System | 90 777 | −1 047 | 2021-09-30 |
0,14867 % | Barclays Capital Inc. | 89 765 | 75 603 | 2021-09-30 |
0,14763 % | Water Island Capital, LLC | 89 140 | 89 140 | 2021-09-30 |
0,14503 % | BNY Mellon Asset Management | 87 571 | −10 251 | 2021-09-30 |
0,14076 % | Western Standard, LLC | 84 990 | 59 955 | 2021-09-30 |
0,13749 % | Wells Capital Management Inc. | 83 014 | −50 293 | 2021-09-30 |
0,13687 % | Managed Account Advisors LLC | 82 644 | −390 | 2021-09-30 |
0,13672 % | Putnam Investment Management, L.L.C. | 82 549 | −143 456 | 2021-09-30 |
0,13623 % | Principal Funds, Inc. | 82 257 | −423 | 2021-09-30 |
0,13581 % | Melqart Asset Management (UK) Limited | 82 000 | 82 000 | 2021-09-30 |
0,13249 % | Carlson Capital, L.P. | 80 000 | 80 000 | 2021-09-30 |
0,13249 % | Spring Creek Capital, LLC | 80 000 | 80 000 | 2021-09-30 |
0,13094 % | AXA Investment Managers UK Ltd. | 79 059 | −89 946 | 2021-09-30 |
0,13064 % | American Century Investment Management, Inc. | 78 882 | −28 941 | 2021-09-30 |
0,13047 % | DWS Investments UK Limited | 78 778 | 75 | 2021-09-30 |
0,12871 % | Weiss Multi-Strategy Advisers LLC | 77 714 | 39 671 | 2021-09-30 |
0,11943 % | Parametric Portfolio Associates LLC | 72 110 | 11 326 | 2021-09-30 |
0,11913 % | Cutler Group, LP | 71 931 | 70 893 | 2021-09-30 |
0,11865 % | J.P. Morgan Securities LLC | 71 642 | 70 667 | 2021-09-30 |
0,11758 % | QVT Financial LP | 70 996 | −30 400 | 2021-09-30 |
0,11492 % | Comerica, Inc. | 69 387 | 20 416 | 2021-06-30 |
0,11431 % | RBC Capital Markets Wealth Management | 69 018 | −1 130 | 2021-09-30 |
0,11243 % | Granahan Investment Management, Inc. | 67 888 | −12 420 | 2021-09-30 |
0,11107 % | DWS Investment GmbH | 67 064 | 0 | 2021-09-30 |
0,10851 % | SEB Investment Management AB | 65 516 | −26 971 | 2021-09-30 |
0,10796 % | Florida State Board of Administration | 65 185 | −658 | 2021-09-30 |