19,03673 % | BVF Partners L.P. | 18 834 936 | 4 263 700 | 2024-06-30 |
12,12856 % | Varuma AG | 11 999 999 | 0 | 2023-12-31 |
6,64857 % | Affiris AG | 6 578 100 | −3 555 374 | 2023-12-15 |
2,44717 % | Pfeifer (Andrea M. A Ph.D.) | 2 421 226 | 56 308 | 2023-12-31 |
1,93441 % | BlackRock Financial Management, Inc. | 1 913 910 | 0 | 2024-06-30 |
1,82707 % | Redmile Group, LLC | 1 807 704 | −199 327 | 2024-06-30 |
1,13404 % | Wells Fargo Advisors | 1 122 017 | 2 314 | 2024-06-30 |
0,96227 % | Platinum Asset Management | 952 069 | −142 957 | 2024-06-30 |
0,83384 % | Avidity Partners Management LP | 825 000 | −3 645 000 | 2024-06-30 |
0,65907 % | Renaissance Technologies LLC | 652 079 | 136 300 | 2024-06-30 |
0,42488 % | BlackRock Institutional Trust Company, N.A. | 420 373 | −14 611 | 2024-06-30 |
0,31529 % | Monin (Jean-Fabien) | 311 950 | 13 794 | 2023-12-31 |
0,25609 % | DWS Investment GmbH | 253 375 | 0 | 2024-06-30 |
0,22628 % | Assenagon Asset Management S.A. | 223 880 | −215 850 | 2024-09-30 |
0,21181 % | ARIAD Asset Management GmbH | 209 568 | 0 | 2024-07-31 |
0,16743 % | BlackRock Investment Management (UK) Ltd. | 165 654 | 79 069 | 2024-06-30 |
0,15161 % | Handelsbanken Kapitalf¿rvaltning AB | 150 000 | 0 | 2024-09-30 |
0,12450 % | Lanthaler (Werner) | 123 184 | 111 278 | 2023-12-31 |
0,10750 % | Millennium Management LLC | 106 363 | 106 363 | 2024-06-30 |
0,10041 % | Two Sigma Investments, LP | 99 343 | 99 343 | 2024-06-30 |
0,10038 % | Eversept Partners, LP | 99 313 | −25 276 | 2024-06-30 |
0,07820 % | Alps Advisors, Inc. | 77 376 | 77 376 | 2024-06-30 |
0,06357 % | Morgan Stanley Smith Barney LLC | 62 894 | 10 497 | 2024-06-30 |
0,06084 % | Dimensional Fund Advisors, L.P. | 60 198 | 446 | 2024-06-30 |
0,05538 % | Geode Capital Management, L.L.C. | 54 797 | 0 | 2024-06-30 |
0,05520 % | Cubist Systematic Strategies, LLC | 54 610 | 54 610 | 2024-06-30 |
0,05493 % | BlackRock Asset Management Ireland Limited | 54 344 | 1 021 | 2024-06-30 |
0,05493 % | BlackRock Advisors (UK) Limited | 54 344 | 1 204 | 2024-09-30 |
0,05372 % | BlackRock Investment Management, LLC | 53 150 | 0 | 2024-06-30 |
0,04176 % | Jump Financial, LLC | 41 321 | 41 321 | 2024-06-30 |
0,03935 % | Williams (Douglas E) | 38 929 | 26 111 | 2023-12-31 |
0,03518 % | Citadel Advisors LLC | 34 808 | −25 924 | 2024-06-30 |
0,03452 % | Twyman (Roy M.D.) | 34 150 | 34 150 | 2023-12-31 |
0,02749 % | Fidelity Management & Research Company LLC | 27 202 | 0 | 2024-06-30 |
0,02569 % | Banque Cantonale Vaudoise | 25 418 | −28 716 | 2024-06-30 |
0,02478 % | Donati (Piergiorgio) | 24 521 | 14 974 | 2023-12-31 |
0,02225 % | Renta 4 Gestora, S.G.I.I.C., S.A. | 22 010 | −6 009 | 2024-06-30 |
0,02035 % | Donovan (Howard) | 20 136 | 15 040 | 2023-12-31 |
0,02021 % | Nomura Securities Co., Ltd. | 20 000 | 20 000 | 2024-06-30 |
0,01960 % | Group One Trading, L.P. | 19 397 | 18 946 | 2024-06-30 |
0,01922 % | China Universal Asset Management Co., Ltd. | 19 021 | 7 400 | 2024-09-30 |
0,01631 % | UBS Financial Services, Inc. | 16 140 | −7 525 | 2024-06-30 |
0,01517 % | Morgan Stanley & Co. LLC | 15 005 | −1 315 547 | 2024-06-30 |
0,01347 % | Goldman Sachs & Company, Inc. | 13 329 | −10 280 | 2024-06-30 |
0,01274 % | Roberts (Christopher) | 12 601 | 10 101 | 2023-12-31 |
0,01202 % | Invesco Capital Management LLC | 11 891 | 8 530 | 2024-06-30 |
0,01152 % | Schonfeld Strategic Advisors LLC | 11 400 | 11 400 | 2024-06-30 |
0,01147 % | J.P. Morgan Securities plc | 11 352 | −10 763 | 2024-06-30 |
0,01011 % | Compagnie Lombard Odier SCmA | 10 000 | 0 | 2024-09-30 |
0,01011 % | Silverberg Bernstein Capital Management, LLC | 10 000 | 0 | 2024-09-30 |
0,00925 % | Shaw (Monica M.D.) | 9 150 | 9 150 | 2023-12-31 |
0,00925 % | Butler (Monika) | 9 150 | 9 150 | 2023-12-31 |
0,00925 % | June (Carl) | 9 150 | 9 150 | 2023-12-31 |
0,00831 % | Mendonca (Nuno) | 8 225 | 8 225 | 2023-12-31 |
0,00817 % | Dimensional Fund Advisors, Ltd. | 8 079 | 0 | 2024-07-31 |
0,00591 % | ProShare Advisors LLC | 5 844 | −77 | 2024-09-30 |
0,00389 % | Z¿rcher Kantonalbank (Asset Management) | 3 851 | −68 | 2024-06-30 |
0,00381 % | Mirae Asset Global Investments Co., Ltd. | 3 774 | 276 | 2024-07-31 |
0,00360 % | BNP Paribas Securities Corp. North America | 3 564 | −7 528 | 2024-06-30 |
0,00321 % | Derouazi (Madiha) | 3 175 | 3 175 | 2023-12-31 |
0,00311 % | Tower Research Capital LLC | 3 074 | −2 756 | 2024-06-30 |
0,00298 % | Mirae Asset Global Investments (USA) LLC | 2 953 | 2 953 | 2024-06-30 |
0,00292 % | BofA Global Research (US) | 2 892 | −22 | 2024-06-30 |
0,00212 % | Citi Investment Research (US) | 2 096 | 1 786 | 2024-06-30 |
0,00169 % | BlackRock Fund Advisors | 1 668 | 0 | 2024-09-30 |
0,00155 % | GF Fund Management Co., Ltd. | 1 536 | 1 536 | 2023-12-31 |
0,00101 % | Activest Wealth Management LLC | 1 000 | 1 000 | 2024-06-30 |
0,00078 % | Parametric Portfolio Associates LLC | 768 | 0 | 2024-06-30 |
0,00077 % | RBC Dominion Securities, Inc. | 760 | −240 | 2024-06-30 |
0,00037 % | Capital Investment Trust Corporation | 367 | −244 | 2024-04-30 |
0,00020 % | Hoopoe Advisors | 200 | 0 | 2024-06-30 |
0,00020 % | SJS Investment Services | 200 | 0 | 2024-09-30 |
0,00005 % | Qube Research & Technologies Ltd | 48 | 0 | 2024-06-30 |
0 % | Vanguard Capital Wealth Advisors, LLC. | 0 | −14 000 | 2024-09-30 |
0 % | Invus Public Equities Advisors, LLC | 0 | −1 000 000 | 2023-03-31 |
0 % | Ergoteles Capital | 0 | −20 014 | 2023-06-30 |
0 % | Squarepoint Capital LLP | 0 | −11 036 | 2023-09-30 |
0 % | Osaic Holdings, Inc. | 0 | −2 000 | 2024-03-31 |
0 % | Watch Point Trust Company LLC | 0 | −12 850 | 2024-03-31 |
0 % | Simplex Trading, LLC | 0 | −635 | 2024-06-30 |
0 % | Bruno Walter Finance SA | 0 | −5 372 | 2023-05-31 |
0 % | Belpointe Asset Management LLC | 0 | −1 000 | 2023-06-30 |
0 % | Glassman Wealth Services LLC | 0 | −26 | 2023-09-30 |
0 % | Landscape Capital Management, L.L.C. | 0 | −117 418 | 2024-06-30 |
0 % | Mariner Wealth Advisors | 0 | −14 368 | 2023-06-30 |
0 % | Virtu Americas LLC | 0 | −11 552 | 2024-03-31 |
0 % | Nixon Peabody Financial Advisors LLC | 0 | −12 850 | 2023-12-31 |
0 % | Jane Street Capital, L.L.C. | 0 | −14 418 | 2024-06-30 |
0 % | Susquehanna International Group, LLP | 0 | −71 487 | 2023-12-31 |
0 % | Morgan Stanley & Co. International Plc | 0 | −137 | 2024-06-30 |
0 % | RBC Capital Partners | 0 | −987 | 2024-06-30 |
0 % | Medical Strategy GmbH | 0 | −87 612 | 2023-03-31 |
0 % | Scoggin Management LP | 0 | −84 401 | 2024-06-30 |
0 % | Acadian Asset Management LLC | 0 | −3 845 | 2023-06-30 |
0 % | Edmond de Rothschild Asset Management (France) S.A. | 0 | −2 000 | 2024-03-31 |
0 % | State Street Global Advisors (US) | 0 | −56 369 | 2023-09-30 |
0 % | Northwestern Mutual Capital, LLC | 0 | −3 400 | 2023-06-30 |
0 % | Lazard Asset Management, L.L.C. | 0 | −10 260 | 2024-06-30 |
0 % | RBC Capital Markets Wealth Management | 0 | −5 100 | 2024-03-31 |
0 % | Farther Finance Advisors, LLC | 0 | −10 | 2024-09-30 |