15,31339 % | RA Capital Management, LP | 10.805.129 | 0 | 30/6/2024 |
5,88298 % | Commodore Capital LP | 4.151.034 | 986.034 | 30/6/2024 |
5,38427 % | Deerfield Management Company, L.P. | 3.799.143 | -1.394.944 | 30/6/2024 |
5,34019 % | Samsara BioCapital, LLC | 3.768.035 | 0 | 30/6/2024 |
5,13418 % | BlackRock Institutional Trust Company, N.A. | 3.622.676 | 1.119.858 | 30/6/2024 |
5,10204 % | Adage Capital Management, L.P. | 3.600.000 | -200.000 | 30/6/2024 |
5,05780 % | New Enterprise Associates (NEA) | 3.568.781 | 0 | 30/6/2024 |
4,88039 % | Boxer Capital, L.L.C. | 3.443.606 | -2.163.744 | 10/10/2024 |
4,72411 % | SR One Capital Management, LP | 3.333.333 | 0 | 30/6/2024 |
4,48049 % | GSK plc | 3.161.432 | 3.161.432 | 27/3/2024 |
4,42947 % | Citadel Advisors LLC | 3.125.434 | 2.703.200 | 30/6/2024 |
4,18987 % | The Vanguard Group, Inc. | 2.956.374 | 990.103 | 30/6/2024 |
4,02004 % | EQT Life Sciences | 2.836.539 | 2.836.539 | 8/2/2024 |
1,97358 % | Wasatch Global Investors Inc | 1.392.555 | 224.063 | 30/6/2024 |
1,67371 % | Columbia Threadneedle Investments (UK) | 1.180.973 | 72.437 | 30/6/2024 |
1,61153 % | Geode Capital Management, L.L.C. | 1.137.099 | 322.691 | 30/6/2024 |
1,53415 % | State Street Global Advisors (US) | 1.082.493 | 453.338 | 30/6/2024 |
1,29731 % | Alyeska Investment Group, L.P. | 915.382 | 377.802 | 30/6/2024 |
1,29375 % | Renaissance Technologies LLC | 912.872 | 98.000 | 30/6/2024 |
1,24150 % | Superstring Capital Management LP | 875.999 | -313.194 | 30/6/2024 |
1,14593 % | T. Rowe Price Investment Management, Inc. | 808.566 | -546.755 | 30/6/2024 |
1,13379 % | OrbiMed Advisors, LLC | 800.000 | 0 | 30/6/2024 |
0,89021 % | Woodline Partners LP | 628.129 | 3.000 | 30/6/2024 |
0,77948 % | Tang Capital Management, LLC | 550.000 | 0 | 30/6/2024 |
0,64664 % | Two Sigma Investments, LP | 456.267 | 208.120 | 30/6/2024 |
0,62354 % | Marshall Wace LLP | 439.973 | 254.104 | 30/6/2024 |
0,43008 % | Acadian Asset Management LLC | 303.461 | 300.767 | 30/6/2024 |
0,42944 % | Northern Trust Investments, Inc. | 303.015 | 31.293 | 30/6/2024 |
0,39920 % | Millennium Management LLC | 281.677 | 245.251 | 30/6/2024 |
0,39536 % | JPMorgan Asset Management U.K. Limited | 278.969 | -53.606 | 30/6/2024 |
0,38440 % | Nuveen LLC | 271.235 | 39.306 | 30/6/2024 |
0,37722 % | BlackRock Financial Management, Inc. | 266.168 | 38.612 | 30/6/2024 |
0,35702 % | Cubist Systematic Strategies, LLC | 251.914 | 251.914 | 30/6/2024 |
0,35431 % | Jefferies LLC | 250.000 | 200.000 | 30/6/2024 |
0,34014 % | Octagon Capital Advisors LP | 240.000 | 0 | 30/6/2024 |
0,33474 % | Blackstone Alternative Asset Management, L.P. | 236.190 | 236.190 | 30/6/2024 |
0,28345 % | Affinity Asset Advisors LLC | 200.000 | 200.000 | 30/6/2024 |
0,25396 % | Squarepoint Capital LLP | 179.194 | 81.998 | 30/6/2024 |
0,24562 % | Wellington Management Company, LLP | 173.306 | 43.932 | 30/6/2024 |
0,24017 % | Bridgeway Capital Management, LLC | 169.467 | 0 | 30/6/2024 |
0,22718 % | BlackRock Investment Management, LLC | 160.296 | 75.860 | 30/6/2024 |
0,22497 % | AQR Capital Management, LLC | 158.736 | 158.736 | 30/6/2024 |
0,22323 % | Morgan Stanley & Co. LLC | 157.509 | 114.851 | 30/6/2024 |
0,20597 % | Charles Schwab Investment Management, Inc. | 145.332 | 55.904 | 30/6/2024 |
0,20544 % | Trager (James) | 144.959 | -456 | 18/6/2024 |
0,19838 % | State of Wisconsin Investment Board | 139.975 | 91.875 | 30/6/2024 |
0,19830 % | Goldman Sachs & Company, Inc. | 139.923 | 113.182 | 30/6/2024 |
0,19694 % | Innovis Asset Management LLC | 138.962 | 138.962 | 30/9/2023 |
0,19274 % | Abaris Investment Management AG | 136.000 | 116.000 | 31/12/2023 |
0,19141 % | Parametric Portfolio Associates LLC | 135.059 | 9.832 | 30/6/2024 |
0,18777 % | Federated MDTA LLC | 132.488 | 132.013 | 30/6/2024 |
0,18751 % | Dimensional Fund Advisors, L.P. | 132.306 | 35.643 | 30/6/2024 |
0,16592 % | D. E. Shaw & Co., L.P. | 117.070 | 117.070 | 30/6/2024 |
0,16299 % | BofA Global Research (US) | 115.009 | 74.637 | 30/6/2024 |
0,16254 % | BNY Mellon Asset Management | 114.691 | 46.039 | 30/6/2024 |
0,15360 % | Jane Street Capital, L.L.C. | 108.377 | -13.650 | 30/6/2024 |
0,12607 % | Barclays Bank PLC | 88.958 | 49.832 | 30/6/2024 |
0,12032 % | Davis (Aaron I) | 84.900 | 84.900 | 8/1/2024 |
0,11906 % | Rhumbline Advisers Ltd. Partnership | 84.011 | 33.117 | 30/6/2024 |
0,11548 % | Goldman Sachs Asset Management, L.P. | 81.481 | 55.614 | 30/6/2024 |
0,11436 % | AllianceBernstein L.P. | 80.690 | 13.870 | 30/6/2024 |
0,11301 % | Brandenberger (Ralph Erik) | 79.743 | -229 | 18/6/2024 |
0,11111 % | Stifel, Nicolaus & Company, Incorporated | 78.401 | -15.533 | 30/6/2024 |
0,10332 % | UBS Financial Services, Inc. | 72.903 | 41.388 | 30/6/2024 |
0,10233 % | American Century Investment Management, Inc. | 72.205 | 24.033 | 30/6/2024 |
0,09890 % | Hastings (Paul J) | 69.787 | -1.770 | 18/6/2024 |
0,09710 % | Schonfeld Strategic Advisors LLC | 68.517 | -331.583 | 30/6/2024 |
0,09573 % | Fidelity Management & Research Company LLC | 67.549 | 2.601 | 30/6/2024 |
0,09525 % | Jump Financial, LLC | 67.205 | 67.205 | 30/6/2024 |
0,08372 % | Dimensional Fund Advisors, Ltd. | 59.074 | 7.228 | 30/9/2024 |
0,08145 % | Mellon Investments Corporation | 57.471 | 30.573 | 30/6/2024 |
0,07795 % | ACCI Capital Investments SGIIC, SA | 55.000 | 5.000 | 31/7/2024 |
0,07459 % | Citi Investment Research (US) | 52.634 | 3.253 | 30/6/2024 |
0,07327 % | Jennison Associates LLC | 51.700 | 0 | 31/8/2024 |
0,06905 % | Hager (Alicia J) | 48.719 | -3.396 | 16/7/2024 |
0,06400 % | Avantis Investors | 45.155 | 18.824 | 31/3/2024 |
0,06257 % | PGIM Quantitative Solutions LLC | 44.150 | 44.150 | 30/6/2024 |
0,05811 % | Bellecapital AG | 41.000 | 24.000 | 31/3/2024 |
0,05712 % | Northern Trust Global Investments | 40.307 | -5.198 | 30/6/2024 |
0,05598 % | T. Rowe Price Japan, Inc. | 39.498 | 39.498 | 31/8/2023 |
0,05576 % | Shook (David M.D.) | 39.342 | 1.352 | 21/8/2024 |
0,05313 % | Simplicity Wealth, LLC | 37.486 | 21.659 | 30/6/2024 |
0,05003 % | Verition Fund Management LLC | 35.298 | 35.298 | 30/6/2024 |
0,04421 % | MetLife Investment Management, LLC | 31.197 | 15.228 | 30/6/2024 |
0,04348 % | Mahmood (Nadir Ahmeduddin) | 30.676 | -526 | 20/6/2023 |
0,04108 % | abrdn Inc. | 28.988 | 0 | 30/9/2024 |
0,04034 % | Corebridge Financial Inc | 28.466 | 28.466 | 30/6/2024 |
0,03295 % | Wells Fargo Bank, N.A. | 23.248 | 12.563 | 30/6/2024 |
0,03282 % | Alpine Global Management, LLC | 23.161 | 23.161 | 30/6/2024 |
0,03262 % | State Street Global Advisors Ireland Limited | 23.015 | -84 | 30/4/2023 |
0,03196 % | JPMorgan Private Bank (United States) | 22.549 | 10.694 | 30/6/2024 |
0,02958 % | Y-Intercept (Hong Kong) Ltd | 20.872 | 20.872 | 30/6/2024 |
0,02935 % | Manulife Investment Management (North America) Limited | 20.710 | 9.975 | 30/6/2024 |
0,02919 % | SG Americas Securities, L.L.C. | 20.597 | 20.597 | 30/9/2024 |
0,02622 % | Susquehanna International Group, LLP | 18.500 | -17.910 | 30/6/2024 |
0,02550 % | Voya Investment Management LLC | 17.994 | 11.388 | 30/6/2024 |
0,02399 % | T. Rowe Price International Ltd | 16.928 | 16.928 | 30/6/2024 |
0,02166 % | Bleakley Financial Group LLC | 15.284 | -22.202 | 30/9/2024 |
0,02154 % | Holistic Planning, L.L.C. | 15.200 | 0 | 30/6/2024 |
0,02123 % | Bayesian Capital Management, LP | 14.979 | 14.979 | 30/6/2024 |