7,05349 % | BlackRock Institutional Trust Company, N.A. | 3.484.424 | -13.509 | 30/9/2021 |
5,60604 % | OrbiMed Advisors, LLC | 2.769.383 | 0 | 30/9/2021 |
5,23893 % | The Vanguard Group, Inc. | 2.588.032 | -15.256 | 30/9/2021 |
4,21872 % | Soleus Capital Management, L.P. | 2.084.050 | 2.084.050 | 30/9/2021 |
3,86671 % | Clearline Capital LP | 1.910.153 | -213.546 | 30/9/2021 |
2,84083 % | Novo Holdings A/S | 1.403.370 | 0 | 30/9/2021 |
2,49634 % | Granahan Investment Management, Inc. | 1.233.194 | -180.109 | 30/9/2021 |
2,33476 % | State Street Global Advisors (US) | 1.153.373 | -2.823.331 | 30/9/2021 |
2,14189 % | Geode Capital Management, L.L.C. | 1.058.094 | 226.660 | 30/9/2021 |
2,02429 % | Versant Ventures | 1.000.000 | 0 | 30/9/2021 |
1,89576 % | TPG Capital, L.P. | 936.507 | 0 | 30/9/2021 |
1,88536 % | Clayman (Michael D) | 931.367 | -13.859 | 19/7/2021 |
1,57480 % | Millennium Management LLC | 777.952 | 202.906 | 30/9/2021 |
1,47409 % | Paradigm Capital Management, Inc. | 728.200 | 628.200 | 30/9/2021 |
1,36682 % | JPMorgan Asset Management U.K. Limited | 675.209 | 105.063 | 30/9/2021 |
1,22322 % | Raymond James Financial Services Advisors, Inc. | 604.271 | 178.506 | 30/9/2021 |
1,06948 % | Acadian Asset Management LLC | 528.324 | 235.514 | 30/9/2021 |
1,03082 % | Jacobs Levy Equity Management, Inc. | 509.225 | -434.540 | 30/9/2021 |
1,02591 % | Two Sigma Investments, LP | 506.800 | -730.929 | 30/9/2021 |
1,01989 % | Victory Capital Management Inc. | 503.828 | -18.000 | 30/9/2021 |
1,01618 % | Bessemer Trust Company, N.A. (US) | 501.994 | 35.748 | 30/4/2021 |
0,91641 % | Northern Trust Investments, Inc. | 452.707 | 2.568 | 30/9/2021 |
0,90021 % | Raymond James & Associates, Inc. | 444.705 | 80.529 | 30/9/2021 |
0,89849 % | BlackRock Financial Management, Inc. | 443.853 | 7.248 | 30/9/2021 |
0,88789 % | Fred Alger Management, LLC | 438.619 | 175.975 | 30/9/2021 |
0,77871 % | Moody National Bank | 384.684 | 74 | 30/9/2021 |
0,74586 % | Zazove Associates, LLC | 368.456 | 78.466 | 30/9/2021 |
0,72972 % | Morgan Stanley & Co. LLC | 360.484 | -119.994 | 30/9/2021 |
0,68067 % | American National Insurance Co | 336.250 | -365 | 30/9/2021 |
0,63516 % | Easterly Investment Partners LLC | 313.770 | 313.770 | 30/9/2021 |
0,63467 % | Snow Capital Management, L.P. | 313.525 | 150 | 30/6/2021 |
0,53963 % | Citadel Advisors LLC | 266.575 | 266.575 | 30/9/2021 |
0,49741 % | Nuveen LLC | 245.719 | 28.953 | 30/9/2021 |
0,42741 % | Gagnon Securities LLC | 211.141 | 2.111 | 30/9/2021 |
0,38891 % | RBC Capital Markets Wealth Management | 192.120 | 2.954 | 30/9/2021 |
0,36660 % | HRT Financial LP | 181.099 | 181.099 | 30/9/2021 |
0,36013 % | Marshall Wace LLP | 177.903 | 177.903 | 30/9/2021 |
0,34716 % | Cubist Systematic Strategies, LLC | 171.497 | 90.961 | 30/9/2021 |
0,32600 % | BMO Asset Management U.S. | 161.045 | 161.045 | 30/9/2021 |
0,32469 % | William Blair & Company, L.L.C. (Research) | 160.399 | 10.299 | 30/9/2021 |
0,32209 % | BlackRock Investment Management, LLC | 159.114 | -15.414 | 30/9/2021 |
0,32156 % | American Financial Group, Inc. | 158.850 | 0 | 30/9/2021 |
0,31066 % | Squarepoint Capital LLP | 153.465 | 55.793 | 30/9/2021 |
0,30648 % | Willwerth (Christina) | 151.402 | -3.945 | 19/7/2021 |
0,28495 % | Susquehanna International Group, LLP | 140.764 | -32.294 | 30/9/2021 |
0,28179 % | Wentworth (Kerry A) | 139.202 | -3.944 | 19/7/2021 |
0,27263 % | Wells Fargo Advisors | 134.678 | 30.276 | 30/9/2021 |
0,26974 % | JP Morgan Asset Management | 133.253 | -9.939 | 30/9/2021 |
0,26573 % | New York State Common Retirement Fund | 131.271 | -61.555 | 30/9/2021 |
0,25449 % | Arkowitz (David A.) | 125.719 | -2.229 | 10/5/2021 |
0,24470 % | Charles Schwab Investment Management, Inc. | 120.880 | -195.445 | 30/9/2021 |
0,24138 % | SG Americas Securities, L.L.C. | 119.243 | 85.462 | 30/9/2021 |
0,24132 % | Invesco Capital Management LLC | 119.210 | 25.715 | 30/9/2021 |
0,23975 % | AQR Capital Management, LLC | 118.437 | 103.995 | 30/9/2021 |
0,23191 % | ExodusPoint Capital Management, LP | 114.564 | 87.417 | 30/9/2021 |
0,21821 % | BNY Mellon Asset Management | 107.797 | -1.745 | 30/9/2021 |
0,21106 % | Ohio Public Employees Retirement System | 104.262 | 0 | 30/9/2021 |
0,21044 % | Layman (Melissa) | 103.956 | 15.580 | 15/3/2021 |
0,20985 % | Muzikant (Adam) | 103.666 | -1.870 | 19/7/2021 |
0,20862 % | BlackRock Investment Management (UK) Ltd. | 103.056 | 18.628 | 30/9/2021 |
0,20354 % | Barclays Bank PLC | 100.547 | 17.925 | 30/9/2021 |
0,20243 % | CM Management, LLC | 100.000 | 25.000 | 30/9/2021 |
0,19291 % | Parametric Portfolio Associates LLC | 95.296 | 59.522 | 30/9/2021 |
0,19105 % | Colella (Samuel D) | 94.381 | 4.500 | 24/6/2021 |
0,18543 % | Trexquant Investment LP | 91.600 | 67.299 | 30/9/2021 |
0,18279 % | Levine Mark S | 90.299 | -3.945 | 19/7/2021 |
0,17816 % | Schweizerische Nationalbank | 88.011 | 0 | 30/9/2021 |
0,15335 % | M & G Investment Management Ltd. | 75.753 | -52.641 | 30/9/2021 |
0,15069 % | GAM Investment Management (Switzerland) AG | 74.442 | -26.753 | 30/9/2021 |
0,15069 % | GAM Capital Management (Switzerland) AG | 74.442 | -60.342 | 30/9/2021 |
0,14778 % | BofA Global Research (US) | 73.004 | -115.837 | 30/9/2021 |
0,14433 % | Belvedere Trading, LLC | 71.300 | 71.300 | 30/9/2021 |
0,14364 % | Commonwealth Financial Network | 70.956 | -2.229 | 30/9/2021 |
0,14147 % | Brandywine Global Investment Management, LLC | 69.885 | -614 | 30/9/2021 |
0,12669 % | Goldman Sachs & Company, Inc. | 62.583 | -769.024 | 30/9/2021 |
0,12605 % | Golden State Equity Partners, L.L.C | 62.270 | 41.670 | 30/9/2021 |
0,12551 % | Birch Grove Capital LP | 62.000 | 0 | 30/9/2021 |
0,12368 % | Kelley (Scott D) | 61.099 | 30.000 | 1/3/2021 |
0,11877 % | California State Teachers Retirement System | 58.674 | -7.726 | 30/9/2021 |
0,11862 % | AllianceBernstein L.P. | 58.600 | 0 | 30/9/2021 |
0,11429 % | BlackRock Advisors (UK) Limited | 56.459 | 1.847 | 31/10/2021 |
0,10693 % | Rhumbline Advisers Ltd. Partnership | 52.824 | 1.884 | 30/9/2021 |
0,10474 % | Credit Suisse Asset Management | 51.743 | 5.108 | 30/9/2021 |
0,10312 % | BlackRock Asset Management Ireland Limited | 50.943 | -6.377 | 30/9/2021 |
0,10121 % | L&S Advisors Inc. | 50.000 | 50.000 | 30/9/2021 |
0,10064 % | Northern Trust Global Investments | 49.715 | -2.429 | 30/9/2021 |
0,09923 % | Florida State Board of Administration | 49.022 | 24.780 | 30/9/2021 |
0,09626 % | American National Registered Investment Advisor, Inc. | 47.550 | -145 | 30/9/2021 |
0,09370 % | EMC Capital Management LLC | 46.287 | 0 | 30/9/2021 |
0,08433 % | Goldman Sachs Asset Management, L.P. | 41.661 | -240.877 | 30/9/2021 |
0,08003 % | Mellon Investments Corporation | 39.533 | 10.778 | 30/9/2021 |
0,07863 % | First Eagle Investment Management, L.L.C. | 38.841 | 30.509 | 30/9/2021 |
0,07692 % | Prelude Capital Management, LLC | 38.000 | 1.700 | 30/9/2021 |
0,07689 % | Russell Investments Trust Company | 37.985 | -1.386 | 30/9/2021 |
0,07470 % | Ergoteles Capital | 36.900 | 36.900 | 30/9/2021 |
0,07373 % | UBS Asset Management (Switzerland) | 36.425 | 0 | 30/9/2021 |
0,07151 % | Mahaffy (Patrick J) | 35.324 | 4.500 | 24/6/2021 |
0,07105 % | Driscoll (Frederick W.) | 35.097 | 35.097 | 1/6/2021 |
0,07085 % | Bellatrix Asset Management | 35.000 | 0 | 30/6/2021 |
0,06974 % | T. Rowe Price Associates, Inc. | 34.451 | 15.393 | 30/9/2021 |