8,53308 % | The Vanguard Group, Inc. | 14.354.342 | -381.474 | 30/6/2024 |
8,12044 % | Wellington Management Company, LLP | 13.660.196 | -1.054.530 | 30/6/2024 |
6,48124 % | BlackRock Institutional Trust Company, N.A. | 10.902.738 | 779.058 | 30/6/2024 |
5,80055 % | Farallon Capital Management, L.L.C. | 9.757.692 | 2.249.820 | 30/6/2024 |
4,49952 % | Baker Bros. Advisors LP | 7.569.090 | 19.841 | 30/6/2024 |
3,74316 % | Nextech Invest, Ltd. | 6.296.740 | 0 | 30/6/2024 |
3,55559 % | BVF Partners L.P. | 5.981.212 | 0 | 30/6/2024 |
3,34386 % | Fidelity Management & Research Company LLC | 5.625.035 | 1.458.597 | 30/6/2024 |
3,15484 % | Alphabet, Inc. | 5.307.075 | 5.563 | 30/6/2024 |
3,12632 % | Paradigm BioCapital Advisors LP | 5.259.089 | 2.344.114 | 30/6/2024 |
3,01455 % | State Street Global Advisors (US) | 5.071.068 | -314.952 | 30/6/2024 |
3,00951 % | T. Rowe Price Associates, Inc. | 5.062.599 | 391.615 | 30/6/2024 |
2,98960 % | Bellevue Asset Management AG | 5.029.100 | -44.500 | 30/6/2024 |
2,75842 % | Janus Henderson Investors | 4.640.218 | 728.099 | 30/6/2024 |
2,61971 % | Casdin Capital, LLC | 4.406.875 | -1.210.724 | 30/6/2024 |
2,54397 % | Boxer Capital, L.L.C. | 4.279.464 | 0 | 30/6/2024 |
1,98291 % | Geode Capital Management, L.L.C. | 3.335.656 | 282.965 | 30/6/2024 |
1,95624 % | Woodline Partners LP | 3.290.791 | -506.357 | 30/6/2024 |
1,83692 % | Deerfield Management Company, L.P. | 3.090.073 | 0 | 30/6/2024 |
1,63389 % | Andreessen Horowitz | 2.748.523 | 0 | 30/6/2024 |
1,40506 % | Balyasny Asset Management LP | 2.363.584 | 708.689 | 30/6/2024 |
1,38541 % | Borisy (Alexis) | 2.330.542 | 4.248 | 20/6/2024 |
1,32225 % | JP Morgan Asset Management | 2.224.283 | -182.612 | 30/6/2024 |
1,30988 % | Holocene Advisors, LP | 2.203.474 | -218.937 | 30/6/2024 |
1,09895 % | Norges Bank Investment Management (NBIM) | 1.848.647 | 1.566.942 | 30/6/2024 |
0,98949 % | Lord, Abbett & Co. LLC | 1.664.516 | -13.315 | 31/8/2024 |
0,71335 % | Logos Global Management LLC | 1.200.000 | 1.200.000 | 30/6/2024 |
0,67939 % | BlackRock Financial Management, Inc. | 1.142.863 | 79.755 | 30/6/2024 |
0,65966 % | Charles Schwab Investment Management, Inc. | 1.109.684 | 57.421 | 30/6/2024 |
0,63729 % | Northern Trust Investments, Inc. | 1.072.055 | -37.405 | 30/6/2024 |
0,61525 % | Goldman Sachs & Company, Inc. | 1.034.972 | 334.291 | 30/6/2024 |
0,60384 % | Invus Public Equities Advisors, LLC | 1.015.776 | -302.873 | 30/6/2024 |
0,59295 % | Frazier Life Sciences Management, L.P. | 997.455 | 0 | 30/6/2024 |
0,56069 % | Rock Springs Capital Management LP | 943.195 | 19.514 | 30/6/2024 |
0,54334 % | Hood River Capital Management LLC | 914.003 | 914.003 | 30/6/2024 |
0,50896 % | Soleus Capital Management, L.P. | 856.178 | 127.478 | 30/6/2024 |
0,50500 % | Morgan Stanley & Co. LLC | 849.505 | 6.716 | 30/6/2024 |
0,48511 % | Marshall Wace LLP | 816.055 | -719.885 | 30/6/2024 |
0,44882 % | Avidity Partners Management LP | 755.000 | 120.000 | 30/6/2024 |
0,43364 % | Finepoint Capital LP | 729.464 | 52.364 | 30/6/2024 |
0,39387 % | Candriam Luxembourg S.A. | 662.564 | 0 | 30/9/2024 |
0,38689 % | Eventide Asset Management, LLC | 650.826 | 289.826 | 30/6/2024 |
0,37767 % | Columbia Threadneedle Investments (UK) | 635.319 | -245.391 | 30/6/2024 |
0,36961 % | JPMorgan Asset Management U.K. Limited | 621.752 | -218.680 | 30/6/2024 |
0,35407 % | Goldsmith Mark A | 595.609 | 0 | 11/10/2024 |
0,32953 % | Candriam Belgium S.A. | 554.334 | -29.616 | 30/6/2024 |
0,32255 % | Victory Capital Management Inc. | 542.601 | -57.980 | 30/6/2024 |
0,32112 % | Pzena Investment Management, LLC | 540.194 | -160.971 | 30/6/2024 |
0,30871 % | American Century Investment Management, Inc. | 519.305 | 519.305 | 30/6/2024 |
0,30430 % | Dafna Capital Management, LLC | 511.894 | 0 | 30/6/2024 |
0,30232 % | MIC Capital Management UK LLP | 508.569 | 0 | 30/6/2024 |
0,29537 % | Columbia Threadneedle Investments (US) | 496.878 | 49.167 | 30/6/2024 |
0,28705 % | BlackRock Advisors (UK) Limited | 482.883 | 617 | 30/9/2024 |
0,27054 % | Sofinnova Investments, Inc | 455.099 | 455.099 | 30/6/2024 |
0,26862 % | BlackRock Asset Management Ireland Limited | 451.870 | 115.991 | 30/6/2024 |
0,24977 % | BlackRock Investment Management, LLC | 420.169 | 59.350 | 30/6/2024 |
0,24360 % | Nuveen LLC | 409.781 | 45.858 | 30/6/2024 |
0,24304 % | Citadel Advisors LLC | 408.842 | -179.246 | 30/6/2024 |
0,23748 % | Goldman Sachs Asset Management, L.P. | 399.489 | -13.221 | 30/6/2024 |
0,23269 % | BlackRock Investment Management (UK) Ltd. | 391.439 | 44.624 | 30/6/2024 |
0,23219 % | Dimensional Fund Advisors, L.P. | 390.583 | -940.676 | 30/6/2024 |
0,22651 % | BofA Global Research (US) | 381.041 | -140.355 | 30/6/2024 |
0,22625 % | Jane Street Capital, L.L.C. | 380.594 | 251.127 | 30/6/2024 |
0,21544 % | BNY Mellon Asset Management | 362.416 | 46.589 | 30/6/2024 |
0,20104 % | Partners HealthCare System, Inc | 338.191 | 0 | 30/9/2024 |
0,19589 % | First Turn Management, LLC | 329.519 | 329.519 | 30/6/2024 |
0,19320 % | Integral Health Asset Management, LLC | 325.000 | -95.000 | 30/6/2024 |
0,19000 % | AllianceBernstein L.P. | 319.618 | -3.746 | 30/6/2024 |
0,18273 % | Columbia Wanger Asset Management, LLC | 307.387 | 0 | 30/6/2024 |
0,17203 % | MPM BioImpact LLC | 289.396 | 16.179 | 30/6/2024 |
0,16808 % | AHL Partners LLP | 282.746 | 253.449 | 30/6/2024 |
0,16526 % | Mubadala Investment Company PJSC | 278.000 | 0 | 30/6/2024 |
0,16021 % | Ensign Peak Advisors, Inc. | 269.504 | 229.721 | 30/6/2024 |
0,15989 % | Mellon Investments Corporation | 268.962 | 65.210 | 30/6/2024 |
0,15639 % | Voya Investment Management LLC | 263.079 | -20.554 | 30/6/2024 |
0,14873 % | TD Asset Management Inc. | 250.194 | -4.400 | 30/6/2024 |
0,14813 % | Qube Research & Technologies Ltd | 249.188 | 81.708 | 30/6/2024 |
0,14472 % | Bessemer Trust Company, N.A. (US) | 243.442 | 0 | 30/6/2024 |
0,13587 % | Rhumbline Advisers Ltd. Partnership | 228.567 | 19.257 | 30/6/2024 |
0,13584 % | Susquehanna Fundamental Investments, LLC | 228.513 | 22.000 | 30/6/2024 |
0,13549 % | Point72 Asset Management, L.P. | 227.922 | 227.922 | 30/6/2024 |
0,13516 % | HSBC Private Bank (Suisse) S.A. | 227.365 | 19.081 | 31/8/2024 |
0,13484 % | Schweizerische Nationalbank | 226.831 | 26.700 | 30/6/2024 |
0,13324 % | Walleye Capital LLC | 224.143 | 189.186 | 30/6/2024 |
0,13095 % | TwinBeech Capital LP | 220.289 | 220.289 | 30/6/2024 |
0,12945 % | UBS Financial Services, Inc. | 217.763 | -87.216 | 30/6/2024 |
0,12624 % | Manulife Investment Management (North America) Limited | 212.368 | 13.318 | 30/6/2024 |
0,11325 % | Raymond James & Associates, Inc. | 190.505 | 116.135 | 30/9/2024 |
0,11035 % | Rafferty Asset Management LLC | 185.637 | -98.715 | 30/6/2024 |
0,10106 % | Adage Capital Management, L.P. | 170.000 | -30.000 | 30/6/2024 |
0,09704 % | Readystate Asset Management LP | 163.241 | 95.941 | 30/6/2024 |
0,09413 % | Kelsey (Stephen Michael) | 158.345 | 0 | 14/10/2024 |
0,09400 % | Nicholas Investment Partners, L.P. | 158.132 | 142.044 | 30/6/2024 |
0,09158 % | T. Rowe Price International Ltd | 154.060 | 10.734 | 30/6/2024 |
0,08446 % | Neuberger Berman, LLC | 142.087 | -1.272 | 30/6/2024 |
0,08177 % | JPMorgan Private Bank (United States) | 137.559 | -1.373 | 30/6/2024 |
0,08009 % | Conestoga Capital Advisors, LLC | 134.721 | -1.296 | 31/3/2024 |
0,07906 % | Acuta Capital Partners, LLC | 133.000 | -10.777 | 30/6/2024 |
0,07844 % | J.P. Morgan Securities plc | 131.944 | 95.918 | 30/6/2024 |
0,07771 % | Legal & General Investment Management Ltd. | 130.725 | 24.596 | 30/6/2024 |