15,00068 % | Fidelity Management & Research Company LLC | 7.513.840 | 8.426 | 30/6/2024 |
9,94798 % | EcoR1 Capital, LLC | 4.982.945 | 1.968.193 | 30/6/2024 |
6,04139 % | Springer Timothy A | 3.026.133 | -4.608.052 | 16/8/2024 |
5,87616 % | BlackRock Institutional Trust Company, N.A. | 2.943.371 | 175.446 | 30/6/2024 |
5,04292 % | Invus Public Equities Advisors, LLC | 2.525.998 | 312.810 | 30/6/2024 |
4,41291 % | The Vanguard Group, Inc. | 2.210.429 | -45.246 | 30/6/2024 |
4,29650 % | T. Rowe Price Associates, Inc. | 2.152.117 | -318.042 | 30/6/2024 |
3,97415 % | Polaris Venture Partners | 1.990.651 | 0 | 1/4/2024 |
3,56000 % | Woodline Partners LP | 1.783.202 | 1.683.202 | 30/6/2024 |
3,27033 % | State Street Global Advisors (US) | 1.638.108 | -1.027.402 | 30/6/2024 |
2,91735 % | Point72 Asset Management, L.P. | 1.461.302 | -3.225.798 | 30/6/2024 |
2,03217 % | Pictet Asset Management Ltd. | 1.017.912 | -168.996 | 30/6/2024 |
1,98642 % | Federated Hermes Global Investment Management Corp. | 995.000 | 0 | 30/6/2024 |
1,93649 % | Geode Capital Management, L.L.C. | 969.986 | 74.786 | 30/6/2024 |
1,22674 % | Tipirneni (Praveen P) | 614.474 | -42.460 | 16/8/2024 |
1,22280 % | OrbiMed Advisors, LLC | 612.500 | 54.000 | 30/6/2024 |
1,15396 % | Two Sigma Investments, LP | 578.020 | -63.831 | 30/6/2024 |
1,06734 % | Goldman Sachs & Company, Inc. | 534.630 | 103.925 | 30/6/2024 |
0,97086 % | SilverArc Capital Management, LLC | 486.306 | 2.334 | 30/6/2024 |
0,73744 % | MPM BioImpact LLC | 369.384 | 44.051 | 30/6/2024 |
0,65451 % | Charles Schwab Investment Management, Inc. | 327.844 | 1.147 | 30/6/2024 |
0,64564 % | BlackRock Financial Management, Inc. | 323.403 | 27.905 | 30/6/2024 |
0,62802 % | Northern Trust Investments, Inc. | 314.575 | -646 | 30/6/2024 |
0,50025 % | Affinity Asset Advisors LLC | 250.573 | 25.573 | 30/6/2024 |
0,48898 % | Wellington Management Company, LLP | 244.931 | -5.569.515 | 31/7/2024 |
0,46266 % | Dafna Capital Management, LLC | 231.748 | 0 | 30/6/2024 |
0,42796 % | Fiduciary Trust Company | 214.366 | 0 | 30/6/2024 |
0,42754 % | Candriam Belgium S.A. | 214.154 | -35.779 | 30/6/2024 |
0,41570 % | Dimensional Fund Advisors, L.P. | 208.225 | -12.937 | 30/6/2024 |
0,32339 % | Citadel Advisors LLC | 161.988 | -704.910 | 30/6/2024 |
0,32121 % | Voloridge Investment Management, LLC | 160.896 | 160.896 | 30/6/2024 |
0,31912 % | Omega Fund Management, LLC | 159.846 | 0 | 30/6/2024 |
0,30509 % | D. E. Shaw & Co., L.P. | 152.819 | -61.637 | 30/6/2024 |
0,30057 % | AllianceBernstein L.P. | 150.558 | 38.776 | 30/6/2024 |
0,29207 % | Nomura Asset Management Co., Ltd. | 146.300 | 146.300 | 30/11/2023 |
0,26968 % | Morgan Stanley & Co. LLC | 135.082 | -67.468 | 30/6/2024 |
0,26208 % | Jane Street Capital, L.L.C. | 131.276 | 85.314 | 30/6/2024 |
0,25893 % | Nuveen LLC | 129.698 | 3.897 | 30/6/2024 |
0,25746 % | Medical Strategy GmbH | 128.962 | -313.051 | 31/12/2023 |
0,23516 % | BlackRock Investment Management, LLC | 117.794 | 24.237 | 30/6/2024 |
0,22736 % | Ensign Peak Advisors, Inc. | 113.883 | -27.340 | 30/6/2024 |
0,22380 % | TD Asset Management Inc. | 112.100 | -13.800 | 30/6/2024 |
0,19753 % | Goldman Sachs Asset Management, L.P. | 98.943 | -14.297 | 30/6/2024 |
0,19217 % | BNY Mellon Asset Management | 96.256 | 5.819 | 30/6/2024 |
0,17721 % | Barclays Bank PLC | 88.766 | 44.039 | 30/6/2024 |
0,17162 % | Manulife Investment Management (North America) Limited | 85.966 | 4.021 | 30/6/2024 |
0,17156 % | Susquehanna International Group, LLP | 85.932 | 16.033 | 30/6/2024 |
0,16814 % | BofA Global Research (US) | 84.223 | -30.339 | 30/6/2024 |
0,15981 % | Allianz Global Investors GmbH | 80.049 | -13.621 | 30/6/2024 |
0,15879 % | Jump Financial, LLC | 79.539 | 67.387 | 30/6/2024 |
0,15525 % | Capital Fund Management S.A. | 77.767 | 58.100 | 30/6/2024 |
0,14885 % | Rafferty Asset Management LLC | 74.557 | -146.237 | 30/6/2024 |
0,14574 % | HOOPP Investment Management | 73.000 | 73.000 | 30/6/2024 |
0,13302 % | Atom Investors LP | 66.628 | -20.002 | 30/6/2024 |
0,13052 % | Rhumbline Advisers Ltd. Partnership | 65.379 | 13.677 | 30/6/2024 |
0,12530 % | BlackRock Asset Management Ireland Limited | 62.765 | 3.150 | 30/6/2024 |
0,11759 % | Schweizerische Nationalbank | 58.900 | 0 | 30/6/2024 |
0,11572 % | Connor, Clark & Lunn Investment Management Ltd. | 57.965 | -46.665 | 30/6/2024 |
0,10994 % | T. Rowe Price International Ltd | 55.070 | 1.643 | 30/6/2024 |
0,10773 % | Mellon Investments Corporation | 53.963 | 21.651 | 30/6/2024 |
0,10730 % | PGIM Quantitative Solutions LLC | 53.747 | -26.180 | 30/6/2024 |
0,09515 % | Saturn V Capital Management LP | 47.660 | -37.972 | 30/6/2024 |
0,08628 % | BlackRock Investment Management (UK) Ltd. | 43.220 | 9.516 | 30/6/2024 |
0,08277 % | UBS Financial Services, Inc. | 41.460 | -107.534 | 30/6/2024 |
0,07797 % | Alps Advisors, Inc. | 39.054 | 3.762 | 30/6/2024 |
0,06813 % | Millennium Management LLC | 34.125 | 34.125 | 30/6/2024 |
0,06610 % | Algert Global LLC | 33.108 | 16.531 | 30/6/2024 |
0,06339 % | Wellington Management Singapore Pte. Ltd. | 31.751 | 31.751 | 31/3/2024 |
0,06339 % | Wellington Management Japan Pte Ltd | 31.751 | -13.447 | 30/6/2023 |
0,05999 % | California State Teachers Retirement System | 30.048 | -631 | 30/6/2024 |
0,05968 % | Carmignac Gestion | 29.892 | 29.892 | 31/7/2024 |
0,05832 % | Legal & General Investment Management Ltd. | 29.214 | -185 | 30/6/2024 |
0,05694 % | Victory Capital Management Inc. | 28.520 | -580 | 30/6/2024 |
0,05660 % | UBS Asset Management (Americas), Inc. | 28.350 | 28.350 | 31/3/2023 |
0,05364 % | First Trust Advisors L.P. | 26.867 | 26.867 | 30/6/2024 |
0,05285 % | PDT Partners, LLC | 26.474 | -34.663 | 30/6/2024 |
0,04991 % | Tudor Investment Corporation | 25.002 | -882 | 30/6/2024 |
0,04951 % | T. Rowe Price Japan, Inc. | 24.799 | 15.500 | 30/4/2024 |
0,04877 % | Aperio Group, LLC | 24.427 | 629 | 30/6/2024 |
0,04873 % | Northern Trust Global Investments | 24.409 | 1.106 | 30/6/2024 |
0,04855 % | UBS Fund Management (Switzerland) AG | 24.319 | -7.904 | 30/6/2024 |
0,04789 % | Mirae Asset Global Investments (USA) LLC | 23.986 | 4.698 | 30/6/2024 |
0,04736 % | Squarepoint Capital LLP | 23.723 | 23.723 | 30/6/2024 |
0,04618 % | American Century Investment Management, Inc. | 23.134 | 16.606 | 30/6/2024 |
0,04607 % | MetLife Investment Management, LLC | 23.077 | 3.665 | 30/6/2024 |
0,04425 % | DeVaul (William David) | 22.167 | 0 | 8/7/2024 |
0,04284 % | Y-Intercept (Hong Kong) Ltd | 21.459 | 21.459 | 30/6/2024 |
0,04278 % | Corebridge Financial Inc | 21.431 | 21.431 | 30/6/2024 |
0,04033 % | Healthinvest Partners AB | 20.199 | 5.247 | 30/6/2024 |
0,03859 % | ExodusPoint Capital Management, LP | 19.330 | 19.330 | 30/6/2024 |
0,03814 % | State of Wisconsin Investment Board | 19.105 | -993 | 30/6/2024 |
0,03753 % | SunAmerica Asset Management, LLC | 18.797 | 533 | 31/3/2024 |
0,03546 % | Edgestream Partners, L.P. | 17.760 | 17.760 | 30/6/2024 |
0,03503 % | DWS Investments UK Limited | 17.547 | -1.922 | 30/6/2024 |
0,03495 % | Wells Fargo Bank, N.A. | 17.504 | 5.837 | 30/6/2024 |
0,03427 % | Kentucky Teachers' Retirement System | 17.167 | 0 | 30/6/2024 |
0,03418 % | Citi Investment Research (US) | 17.122 | -173.223 | 30/6/2024 |
0,03389 % | JPMorgan Private Bank (United States) | 16.976 | 2.137 | 30/6/2024 |
0,03294 % | Guggenheim Investments | 16.502 | -7.291 | 31/8/2024 |
0,03265 % | UBS Asset Management (Switzerland) | 16.354 | 4.400 | 30/6/2024 |