11,39730 % | Janus Henderson Investors | 2.485.751 | -115.531 | 30/6/2024 |
9,42483 % | Avoro Capital Advisors LLC | 2.055.555 | 111.111 | 30/6/2024 |
9,05360 % | Baker Bros. Advisors LP | 1.974.590 | 4.792 | 30/6/2024 |
8,78433 % | RTW Investments L.P. | 1.915.862 | 1.518.815 | 30/6/2024 |
8,48235 % | Paulson & Co. Inc. | 1.850.000 | 75.000 | 30/6/2024 |
8,27190 % | The Vanguard Group, Inc. | 1.804.102 | 137.898 | 30/6/2024 |
5,80662 % | BlackRock Institutional Trust Company, N.A. | 1.266.424 | 183.195 | 30/6/2024 |
4,99680 % | Taub (Rebecca A) | 1.089.802 | 650.804 | 22/4/2024 |
4,20389 % | Friedman (Paul A) | 916.868 | 714 | 25/6/2024 |
3,85727 % | T. Rowe Price Associates, Inc. | 841.271 | 53.080 | 30/6/2024 |
3,41455 % | State Street Global Advisors (US) | 744.714 | 119.776 | 30/6/2024 |
3,09025 % | Fidelity Management & Research Company LLC | 673.983 | 68.468 | 30/6/2024 |
3,00569 % | SQN, L.L.C. | 655.540 | 0 | 22/4/2024 |
1,99513 % | Craves (Frederick B) | 435.138 | -15.000 | 13/9/2024 |
1,83335 % | Geode Capital Management, L.L.C. | 399.854 | 52.997 | 30/6/2024 |
1,58223 % | Artisan Partners Limited Partnership | 345.085 | -56.624 | 30/6/2024 |
1,21320 % | Perceptive Advisors LLC | 264.600 | -165.353 | 30/6/2024 |
1,12563 % | Rock Springs Capital Management LP | 245.499 | -40.432 | 30/6/2024 |
0,85921 % | ArrowMark Colorado Holdings, LLC | 187.393 | 153.174 | 30/6/2024 |
0,68776 % | Armistice Capital LLC | 150.000 | -18.000 | 30/6/2024 |
0,68447 % | TCG Crossover Management, LLC | 149.283 | 0 | 30/6/2024 |
0,63588 % | BofA Global Research (US) | 138.686 | 105.463 | 30/6/2024 |
0,63418 % | Charles Schwab Investment Management, Inc. | 138.314 | 15.622 | 30/6/2024 |
0,63415 % | Woodline Partners LP | 138.309 | 118.609 | 30/6/2024 |
0,62941 % | Pictet Asset Management Ltd. | 137.275 | -46.888 | 30/6/2024 |
0,62467 % | UBS Financial Services, Inc. | 136.240 | 10.825 | 30/6/2024 |
0,62001 % | Morgan Stanley & Co. LLC | 135.224 | -72.014 | 30/6/2024 |
0,59848 % | Tao Capital Management LP | 130.529 | 0 | 30/6/2024 |
0,57451 % | Polar Capital LLP | 125.300 | 95 | 30/6/2024 |
0,55347 % | Northern Trust Investments, Inc. | 120.712 | -145 | 30/6/2024 |
0,55012 % | Invesco Advisers, Inc. | 119.982 | 54.331 | 30/6/2024 |
0,53199 % | Norges Bank Investment Management (NBIM) | 116.027 | -29.562 | 30/6/2024 |
0,52737 % | Fidelity Institutional Asset Management | 115.020 | 6.621 | 30/6/2024 |
0,52136 % | Fiera Capital Inc. | 113.709 | 113.709 | 30/6/2024 |
0,50946 % | American Century Investment Management, Inc. | 111.113 | 13.361 | 30/6/2024 |
0,50436 % | Affinity Asset Advisors LLC | 110.000 | -5.000 | 30/6/2024 |
0,49445 % | Goldman Sachs & Company, Inc. | 107.839 | 38.878 | 30/6/2024 |
0,46976 % | Fred Alger Management, LLC | 102.455 | 37.879 | 30/6/2024 |
0,45491 % | Rheos Capital Works Inc. | 99.215 | -11.000 | 30/9/2024 |
0,42496 % | Managed Account Advisors LLC | 92.683 | 14.387 | 30/6/2024 |
0,42041 % | Mirae Asset Global Investments (USA) LLC | 91.691 | -562 | 30/6/2024 |
0,41371 % | Pictet Asset Management (Japan) Ltd. | 90.230 | 34.875 | 30/4/2024 |
0,38787 % | AlpInvest Partners B.V. | 84.595 | -21.149 | 30/6/2024 |
0,38227 % | Ensign Peak Advisors, Inc. | 83.373 | -8.845 | 30/6/2024 |
0,38084 % | Connor, Clark & Lunn Investment Management Ltd. | 83.062 | -10.535 | 30/6/2024 |
0,35029 % | Group One Trading, L.P. | 76.399 | 33.228 | 30/6/2024 |
0,34388 % | EcoR1 Capital, LLC | 75.000 | 0 | 30/6/2024 |
0,32639 % | MPM BioImpact LLC | 71.185 | 9.786 | 30/6/2024 |
0,32119 % | BlackRock Financial Management, Inc. | 70.051 | 19.642 | 30/6/2024 |
0,31977 % | Nuveen LLC | 69.741 | 9.288 | 30/6/2024 |
0,29964 % | Tri Locum Partners LP | 65.352 | 11.997 | 30/6/2024 |
0,29166 % | Goldman Sachs Asset Management, L.P. | 63.612 | 40.784 | 30/6/2024 |
0,27210 % | Morgan Stanley Smith Barney LLC | 59.345 | -1.560 | 30/6/2024 |
0,25624 % | Sibold (William John) | 55.887 | -6.363 | 9/9/2024 |
0,25552 % | TD Asset Management Inc. | 55.730 | 5.400 | 30/6/2024 |
0,22445 % | Emerald Advisers LLC | 48.952 | -123.571 | 30/9/2024 |
0,21295 % | New York State Common Retirement Fund | 46.445 | -4.728 | 30/9/2024 |
0,20967 % | University of Wisconsin Foundation | 45.730 | -10.646 | 30/6/2024 |
0,20706 % | BlackRock Investment Management, LLC | 45.159 | 9.730 | 30/6/2024 |
0,20436 % | AllianceBernstein L.P. | 44.570 | 16.670 | 30/6/2024 |
0,20365 % | Sofinnova Investments, Inc | 44.417 | 25.388 | 30/6/2024 |
0,20224 % | Bessemer Trust Company, N.A. (US) | 44.109 | -10.360 | 31/7/2024 |
0,19730 % | Propel Bio Management, LLC | 43.032 | 0 | 30/6/2024 |
0,19725 % | Voya Investment Management LLC | 43.020 | 25.493 | 30/6/2024 |
0,19695 % | BNY Mellon Asset Management | 42.954 | 8.609 | 30/6/2024 |
0,18779 % | Point72 Asset Management, L.P. | 40.958 | -52.613 | 30/6/2024 |
0,17716 % | DWS Investment GmbH | 38.638 | 0 | 30/6/2024 |
0,17596 % | Gilder Gagnon Howe & Co. LLC | 38.377 | -706 | 30/6/2024 |
0,17326 % | JP Morgan Asset Management | 37.787 | -351 | 30/6/2024 |
0,16965 % | UBS Switzerland AG | 37.000 | 37.000 | 30/6/2024 |
0,16698 % | Rafferty Asset Management LLC | 36.418 | 501 | 30/6/2024 |
0,16600 % | Jane Street Capital, L.L.C. | 36.204 | 11.053 | 30/6/2024 |
0,16359 % | Manulife Investment Management (North America) Limited | 35.678 | 4.937 | 30/6/2024 |
0,16099 % | SEB Investment Management AB | 35.112 | 0 | 30/6/2024 |
0,14901 % | Handelsbanken Kapitalf¿rvaltning AB | 32.500 | 900 | 30/9/2024 |
0,13779 % | CIBC Private Wealth Management | 30.051 | 1 | 30/6/2024 |
0,13743 % | PFM Health Sciences, LP | 29.973 | 0 | 30/6/2024 |
0,13067 % | Macquarie Investment Management | 28.500 | -30.457 | 30/6/2024 |
0,12918 % | Mellon Investments Corporation | 28.174 | 7.313 | 30/6/2024 |
0,12150 % | Rhenman & Partners Asset Management AB | 26.500 | -10.000 | 30/6/2024 |
0,11758 % | T. Rowe Price Investment Management, Inc. | 25.644 | -17.342 | 30/6/2024 |
0,11624 % | Rhumbline Advisers Ltd. Partnership | 25.351 | 4.209 | 30/6/2024 |
0,11371 % | Schweizerische Nationalbank | 24.800 | 1.400 | 30/6/2024 |
0,11215 % | Schonfeld Strategic Advisors LLC | 24.460 | 24.460 | 30/6/2024 |
0,11188 % | Erste Asset Management GmbH | 24.400 | 0 | 31/8/2024 |
0,11010 % | Wells Fargo Advisors | 24.012 | 11.742 | 30/6/2024 |
0,10843 % | Rokos Capital Management LLP | 23.649 | -14.113 | 30/6/2024 |
0,10689 % | Simplify Asset Management Inc | 23.313 | 19 | 30/6/2024 |
0,10671 % | BlackRock Advisors (UK) Limited | 23.274 | 585 | 30/9/2024 |
0,10207 % | California Public Employees' Retirement System | 22.262 | 2.072 | 30/6/2024 |
0,09798 % | Wintrust Investments, LLC | 21.370 | 2.100 | 30/6/2024 |
0,09275 % | BlackRock Asset Management Ireland Limited | 20.229 | 1.340 | 30/6/2024 |
0,09037 % | Parametric Portfolio Associates LLC | 19.710 | 4.141 | 30/6/2024 |
0,08910 % | Raymond James & Associates, Inc. | 19.433 | -888 | 30/9/2024 |
0,08752 % | Rockefeller Capital Management | 19.088 | -16.073 | 30/6/2024 |
0,08674 % | Hennion & Walsh Asset Management, Inc. | 18.917 | -1.420 | 30/9/2024 |
0,08391 % | International Biotechnology Trust PLC | 18.300 | 0 | 30/9/2023 |
0,08021 % | T. Rowe Price International Ltd | 17.494 | 2.472 | 30/6/2024 |
0,07365 % | Citi Investment Research (US) | 16.062 | -16.728 | 30/6/2024 |
0,07244 % | Cutler Group, LP | 15.800 | 2.300 | 31/3/2024 |