12,22467 % | Cormorant Asset Management, LP | 8.325.000 | 0 | 30/6/2024 |
7,60033 % | Suvretta Capital Management, LLC | 5.175.823 | 1.411.935 | 30/6/2024 |
5,35766 % | Franklin Advisers, Inc. | 3.648.569 | 287.636 | 30/6/2024 |
5,27374 % | Adage Capital Management, L.P. | 3.591.420 | -1.564.879 | 30/6/2024 |
4,86301 % | BlackRock Institutional Trust Company, N.A. | 3.311.710 | 819.437 | 30/6/2024 |
4,06025 % | The Vanguard Group, Inc. | 2.765.031 | 378.226 | 30/6/2024 |
3,55509 % | T. Rowe Price Associates, Inc. | 2.421.017 | 14.918 | 30/6/2024 |
3,04194 % | T. Rowe Price Investment Management, Inc. | 2.071.563 | 466.800 | 30/6/2024 |
2,43666 % | Morgan Stanley & Co. LLC | 1.659.365 | 455.210 | 30/6/2024 |
2,27830 % | EW Healthcare Partners | 1.551.521 | 0 | 30/6/2024 |
1,98903 % | Citadel Advisors LLC | 1.354.532 | -20.985 | 30/6/2024 |
1,79109 % | State Street Global Advisors (US) | 1.219.729 | 187.157 | 30/6/2024 |
1,60573 % | Octagon Capital Advisors LP | 1.093.503 | 0 | 30/6/2024 |
1,57500 % | Laurion Capital Management LP | 1.072.577 | 443.181 | 30/6/2024 |
1,51594 % | Geode Capital Management, L.L.C. | 1.032.357 | 199.720 | 30/6/2024 |
1,35438 % | TCG Crossover Management, LLC | 922.335 | 922.335 | 30/6/2024 |
1,28897 % | Deerfield Management Company, L.P. | 877.790 | 298.196 | 30/6/2024 |
1,27690 % | Columbia Threadneedle Investments (US) | 869.570 | 264.475 | 30/6/2024 |
1,14053 % | Two Sigma Investments, LP | 776.702 | 660.412 | 30/6/2024 |
1,11712 % | Goldman Sachs & Company, Inc. | 760.759 | -44.365 | 30/6/2024 |
1,03877 % | Finepoint Capital LP | 707.404 | 50.804 | 30/6/2024 |
0,98031 % | Fiera Capital Inc. | 667.592 | 3.465 | 30/6/2024 |
0,94020 % | Perceptive Advisors LLC | 640.274 | 50.628 | 30/6/2024 |
0,92624 % | Point72 Asset Management, L.P. | 630.769 | 630.769 | 30/6/2024 |
0,85274 % | Millennium Management LLC | 580.716 | -1.465.722 | 30/6/2024 |
0,82876 % | DWS Investments UK Limited | 564.383 | -201.675 | 30/6/2024 |
0,77473 % | Morgan Stanley Investment Management Inc. (US) | 527.593 | 527.376 | 30/6/2024 |
0,69934 % | Cubist Systematic Strategies, LLC | 476.250 | 425.717 | 30/6/2024 |
0,56241 % | Candriam Belgium S.A. | 383.000 | 0 | 30/6/2024 |
0,54915 % | Walleye Capital LLC | 373.974 | 187.016 | 30/6/2024 |
0,43493 % | Northern Trust Investments, Inc. | 296.190 | -2.668 | 30/6/2024 |
0,43014 % | PFM Health Sciences, LP | 292.926 | 122.055 | 30/6/2024 |
0,42616 % | Federated MDTA LLC | 290.212 | -352.964 | 30/6/2024 |
0,41529 % | SEB Investment Management AB | 282.814 | 0 | 30/6/2024 |
0,39631 % | Susquehanna International Group, LLP | 269.885 | 220.808 | 30/6/2024 |
0,38691 % | AXA Investment Managers UK Ltd. | 263.483 | 148 | 30/6/2024 |
0,36909 % | Alyeska Investment Group, L.P. | 251.348 | 103.511 | 30/6/2024 |
0,36711 % | HSBC Private Bank (Suisse) S.A. | 250.000 | 0 | 31/8/2024 |
0,34047 % | Oracle Investment Management, Inc. | 231.857 | -230.000 | 30/6/2024 |
0,32970 % | Lurker (Nancy S) | 224.524 | 3.173 | 16/8/2024 |
0,29564 % | Granahan Investment Management, LLC | 201.332 | 201.332 | 30/6/2024 |
0,27886 % | UBS Financial Services, Inc. | 189.903 | -266.723 | 30/6/2024 |
0,27828 % | BofA Global Research (US) | 189.510 | 112.273 | 30/6/2024 |
0,24861 % | Trexquant Investment LP | 169.305 | 36.812 | 30/6/2024 |
0,24055 % | Nuveen LLC | 163.816 | 7.882 | 30/6/2024 |
0,22438 % | Renaissance Technologies LLC | 152.800 | 80.900 | 30/6/2024 |
0,21219 % | BlackRock Investment Management, LLC | 144.500 | 47.871 | 30/6/2024 |
0,20873 % | Essex Investment Management Company, LLC | 142.144 | 99.606 | 30/9/2024 |
0,20843 % | BlackRock Financial Management, Inc. | 141.942 | 32.920 | 30/6/2024 |
0,20488 % | State of Wisconsin Investment Board | 139.526 | 82.142 | 30/6/2024 |
0,19794 % | Charles Schwab Investment Management, Inc. | 134.796 | 34.946 | 30/6/2024 |
0,19599 % | BNY Mellon Asset Management | 133.472 | 32.356 | 30/6/2024 |
0,18751 % | TD Asset Management Inc. | 127.694 | -15.200 | 30/6/2024 |
0,18734 % | Corient Private Wealth LLC | 127.579 | 74.681 | 30/6/2024 |
0,18373 % | Schroder Investment Management Ltd. (SIM) | 125.122 | -181.084 | 30/6/2024 |
0,17727 % | PanAgora Asset Management Inc. | 120.721 | 81.201 | 30/6/2024 |
0,17707 % | Connor, Clark & Lunn Investment Management Ltd. | 120.587 | -44.525 | 30/6/2024 |
0,17662 % | BlackRock Advisors (UK) Limited | 120.280 | 962 | 30/9/2024 |
0,17062 % | Balyasny Asset Management LP | 116.195 | 116.195 | 30/6/2024 |
0,17045 % | Jones (David Scott) | 116.079 | 6.311 | 9/2/2024 |
0,16892 % | Qube Research & Technologies Ltd | 115.037 | 109.088 | 30/6/2024 |
0,16740 % | Medical Strategy GmbH | 114.000 | -16.200 | 30/6/2024 |
0,15889 % | BlackRock Asset Management Ireland Limited | 108.205 | 52.581 | 30/6/2024 |
0,15823 % | Wellington Management Company, LLP | 107.756 | 13.195 | 30/6/2024 |
0,15040 % | Jump Financial, LLC | 102.422 | 102.422 | 30/6/2024 |
0,14947 % | Jane Street Capital, L.L.C. | 101.787 | -112.907 | 30/6/2024 |
0,14944 % | Schonfeld Strategic Advisors LLC | 101.772 | 101.772 | 30/6/2024 |
0,14905 % | Artia Global Partners LP | 101.500 | 50.000 | 30/6/2024 |
0,14717 % | Ocumension Therapeutics | 100.221 | -1 | 23/4/2024 |
0,14684 % | SilverArc Capital Management, LLC | 100.000 | -147.968 | 30/6/2024 |
0,14684 % | MYDA Advisors LLC | 100.000 | -15.000 | 30/6/2024 |
0,13671 % | Schweizerische Nationalbank | 93.100 | 6.400 | 30/6/2024 |
0,11946 % | T. Rowe Price International Ltd | 81.354 | 21.638 | 30/6/2024 |
0,11815 % | Graham Capital Management, L.P. | 80.459 | -3.900 | 30/6/2024 |
0,11282 % | Rhumbline Advisers Ltd. Partnership | 76.833 | 18.897 | 30/6/2024 |
0,10496 % | Woodstock Corporation | 71.480 | 16.093 | 30/9/2024 |
0,10152 % | DWS Investment Management Americas, Inc. | 69.136 | -528 | 30/6/2024 |
0,09992 % | Manulife Investment Management (North America) Limited | 68.043 | -8.496 | 30/6/2024 |
0,09850 % | Paggiarino Dario A | 67.080 | -76.754 | 23/4/2024 |
0,09542 % | Managed Account Advisors LLC | 64.982 | 1.714 | 30/6/2024 |
0,09241 % | Zaderej (Karen L) | 62.933 | 12.500 | 19/8/2024 |
0,08888 % | Duker (Jay S) | 60.527 | 8.607 | 10/7/2024 |
0,08777 % | Parametric Portfolio Associates LLC | 59.769 | -3.767 | 30/6/2024 |
0,08306 % | Mellon Investments Corporation | 56.562 | 20.098 | 30/6/2024 |
0,08232 % | Wells Fargo Advisors | 56.059 | -2.833 | 30/6/2024 |
0,07810 % | Dynamic Technology Lab Pte. Ltd. | 53.188 | 38.479 | 30/6/2024 |
0,07601 % | AllianceBernstein L.P. | 51.760 | 24.160 | 30/6/2024 |
0,07443 % | BlackRock Investment Management (UK) Ltd. | 50.687 | 21.869 | 30/6/2024 |
0,07406 % | Adamis (Anthony P) | 50.433 | 2.000 | 23/6/2024 |
0,07342 % | 5AM Ventures | 50.000 | 50.000 | 30/6/2024 |
0,07328 % | Corton Capital Inc | 49.905 | 38.126 | 30/6/2024 |
0,07240 % | Envestnet Asset Management, Inc. | 49.301 | 970 | 30/6/2024 |
0,07189 % | D. E. Shaw & Co., L.P. | 48.959 | 48.959 | 30/6/2024 |
0,07050 % | Barclays Bank PLC | 48.012 | -117.675 | 30/6/2024 |
0,07048 % | Bridgeway Capital Management, LLC | 48.000 | -6.100 | 30/6/2024 |
0,06972 % | Elston (George O) | 47.480 | 3.873 | 25/5/2024 |
0,06822 % | Squarepoint Capital LLP | 46.456 | -92.203 | 30/6/2024 |
0,06810 % | California State Teachers Retirement System | 46.374 | 3.099 | 30/6/2024 |
0,06510 % | Legal & General Investment Management Ltd. | 44.331 | 7.416 | 30/6/2024 |
0,06493 % | UBS Asset Management (Switzerland) | 44.216 | 44.216 | 30/6/2024 |