13,53207 % | Frazier Life Sciences Management, L.P. | 6 495 392 | 0 | 30.6.2024 |
10,39322 % | Janus Henderson Investors | 4 988 747 | 2 221 537 | 30.6.2024 |
9,10422 % | BVF Partners L.P. | 4 370 024 | 0 | 30.6.2024 |
7,53087 % | Eventide Asset Management, LLC | 3 614 820 | 314 420 | 30.6.2024 |
6,11390 % | BlackRock Institutional Trust Company, N.A. | 2 934 672 | 680 132 | 30.6.2024 |
5,08164 % | The Vanguard Group, Inc. | 2 439 185 | 233 265 | 30.6.2024 |
3,69175 % | Rock Springs Capital Management LP | 1 772 038 | −84 526 | 30.6.2024 |
3,30338 % | Citadel Advisors LLC | 1 585 624 | 193 118 | 30.6.2024 |
3,12500 % | Novo Holdings A/S | 1 500 000 | 0 | 30.9.2024 |
3,11712 % | State Street Global Advisors (US) | 1 496 217 | −1 326 255 | 30.6.2024 |
2,68147 % | Tang Capital Management, LLC | 1 287 107 | 100 000 | 30.6.2024 |
2,57317 % | Cadian Capital Management LP | 1 235 121 | −1 057 446 | 30.6.2024 |
2,43999 % | T. Rowe Price Associates, Inc. | 1 171 197 | −413 444 | 30.6.2024 |
2,28188 % | Medical Strategy GmbH | 1 095 302 | −31 500 | 30.6.2024 |
1,95600 % | Franklin Advisers, Inc. | 938 881 | 0 | 30.6.2024 |
1,88996 % | Geode Capital Management, L.L.C. | 907 180 | 210 041 | 30.6.2024 |
1,82315 % | Pictet Asset Management Ltd. | 875 113 | −80 801 | 30.6.2024 |
1,54385 % | Polar Capital LLP | 741 049 | 116 049 | 30.6.2024 |
1,52313 % | Avidity Partners Management LP | 731 104 | −411 746 | 30.6.2024 |
1,51384 % | Goldman Sachs & Company, Inc. | 726 645 | 60 085 | 30.6.2024 |
1,46541 % | First Turn Management, LLC | 703 398 | −255 256 | 30.6.2024 |
1,45819 % | ClearBridge Investments, LLC | 699 933 | 436 349 | 30.6.2024 |
1,41237 % | William Blair Investment Management, LLC | 677 939 | 50 667 | 30.6.2024 |
1,28213 % | Norges Bank Investment Management (NBIM) | 615 421 | −111 161 | 30.6.2024 |
1,09856 % | Morgan Stanley & Co. LLC | 527 308 | 184 709 | 30.6.2024 |
1,09100 % | Boone Capital Management LLC | 523 679 | 71 781 | 30.6.2024 |
1,05932 % | Candriam Belgium S.A. | 508 475 | 508 475 | 30.6.2024 |
1,05932 % | Candriam Luxembourg S.A. | 508 475 | 0 | 30.9.2024 |
1,02619 % | MPM BioImpact LLC | 492 569 | 492 569 | 30.6.2024 |
0,88748 % | AXA Investment Managers UK Ltd. | 425 992 | −167 794 | 30.6.2024 |
0,85774 % | Lord, Abbett & Co. LLC | 411 713 | −359 | 31.8.2024 |
0,80316 % | Nuveen LLC | 385 515 | 76 207 | 30.6.2024 |
0,79781 % | Grey (Michael G) | 382 948 | 0 | 15.2.2024 |
0,71550 % | Two Sigma Investments, LP | 343 440 | −8 913 | 30.6.2024 |
0,69865 % | Peetz (Christopher) | 335 353 | 34 013 | 23.7.2024 |
0,65583 % | Prosight Capital | 314 800 | −150 200 | 30.6.2024 |
0,64794 % | Charles Schwab Investment Management, Inc. | 311 012 | 39 358 | 30.6.2024 |
0,60289 % | BofA Global Research (US) | 289 386 | −6 080 | 30.6.2024 |
0,58778 % | Invesco Advisers, Inc. | 282 133 | 244 801 | 30.6.2024 |
0,55301 % | Millennium Management LLC | 265 443 | −274 223 | 30.6.2024 |
0,52217 % | Northern Trust Investments, Inc. | 250 642 | −2 002 | 30.6.2024 |
0,51699 % | DWS Investments UK Limited | 248 153 | 5 168 | 30.6.2024 |
0,50565 % | Rice Hall James & Associates, LLC | 242 711 | 12 981 | 30.9.2024 |
0,50240 % | PENN Capital Management Company, Inc. | 241 151 | −4 545 | 30.6.2024 |
0,47645 % | Barclays Bank PLC | 228 694 | −46 172 | 30.6.2024 |
0,47573 % | New York State Common Retirement Fund | 228 351 | 38 226 | 30.9.2024 |
0,46378 % | Ensign Peak Advisors, Inc. | 222 614 | 0 | 30.6.2024 |
0,45935 % | Silvercrest Asset Management Group LLC | 220 490 | 57 673 | 30.6.2024 |
0,44272 % | Citi Investment Research (US) | 212 504 | −158 547 | 30.6.2024 |
0,42442 % | Woodline Partners LP | 203 720 | −29 547 | 30.6.2024 |
0,39683 % | Baker Bros. Advisors LP | 190 476 | 0 | 30.6.2024 |
0,37500 % | Ardsley Advisory Partners LP | 180 000 | −65 000 | 30.6.2024 |
0,33333 % | Adage Capital Management, L.P. | 160 000 | 0 | 30.6.2024 |
0,33098 % | AXA Investment Managers Paris | 158 870 | 0 | 31.8.2024 |
0,32292 % | Affinity Asset Advisors LLC | 155 000 | −5 000 | 30.6.2024 |
0,28673 % | Raymond James & Associates, Inc. | 137 628 | −6 586 | 30.9.2024 |
0,27969 % | Rhenman & Partners Asset Management AB | 134 250 | 42 000 | 30.6.2024 |
0,26111 % | BlackRock Financial Management, Inc. | 125 332 | 57 231 | 30.6.2024 |
0,25621 % | Highlander Partners, L.P. | 122 980 | 0 | 30.6.2024 |
0,25555 % | Jane Street Capital, L.L.C. | 122 664 | 8 059 | 30.6.2024 |
0,24178 % | Hennion & Walsh Asset Management, Inc. | 116 054 | 11 284 | 30.9.2024 |
0,22822 % | Raymond James Financial Services Advisors, Inc. | 109 545 | 10 662 | 30.9.2024 |
0,22104 % | Nan Fung Life Sciences | 106 100 | 10 000 | 30.6.2024 |
0,21847 % | Knights of Columbus | 104 865 | 2 587 | 30.6.2024 |
0,21830 % | BlackRock Investment Management, LLC | 104 786 | 42 873 | 30.6.2024 |
0,21751 % | Longpre (Lara) | 104 407 | −847 | 2.2.2024 |
0,21622 % | Vig (Pamela) | 103 785 | 0 | 24.6.2024 |
0,20642 % | BNY Mellon Asset Management | 99 080 | 32 658 | 30.6.2024 |
0,16499 % | SilverArc Capital Management, LLC | 79 194 | 0 | 30.6.2024 |
0,15712 % | Wellington Management Company, LLP | 75 416 | 4 974 | 30.6.2024 |
0,15667 % | Healthinvest Partners AB | 75 200 | −47 800 | 30.6.2024 |
0,14345 % | Rafferty Asset Management LLC | 68 858 | −197 404 | 30.6.2024 |
0,14063 % | International Biotechnology Trust PLC | 67 500 | 0 | 30.9.2023 |
0,14046 % | Squarepoint Capital LLP | 67 421 | 26 154 | 30.6.2024 |
0,13500 % | Schweizerische Nationalbank | 64 800 | 5 500 | 30.6.2024 |
0,13479 % | Palo Alto Investors LP | 64 700 | 0 | 30.6.2024 |
0,13333 % | LifeSci Fund Management LLC | 64 000 | −30 000 | 30.6.2024 |
0,12583 % | Phocas Financial Corporation | 60 399 | −1 137 | 30.6.2024 |
0,11780 % | BlackRock Advisors (UK) Limited | 56 542 | 862 | 30.9.2024 |
0,11763 % | State of Wisconsin Investment Board | 56 464 | 10 647 | 30.6.2024 |
0,11024 % | Rhumbline Advisers Ltd. Partnership | 52 916 | 17 279 | 30.6.2024 |
0,10571 % | UBS Financial Services, Inc. | 50 743 | −106 168 | 30.6.2024 |
0,09980 % | Boston Advisors, LLC | 47 902 | 0 | 31.8.2024 |
0,09552 % | Connor, Clark & Lunn Investment Management Ltd. | 45 849 | 45 849 | 30.6.2024 |
0,09375 % | AlphaCentric Advisors LLC. | 45 000 | −19 000 | 30.9.2024 |
0,09186 % | Arctic Fund Management AS | 44 095 | −1 500 | 30.4.2024 |
0,09135 % | Mellon Investments Corporation | 43 849 | 16 754 | 30.6.2024 |
0,09114 % | ExodusPoint Capital Management, LP | 43 747 | −20 672 | 30.6.2024 |
0,08875 % | BMO Capital Markets (US) | 42 600 | −2 400 | 30.6.2024 |
0,08709 % | BlackRock Asset Management Ireland Limited | 41 803 | 1 428 | 30.6.2024 |
0,08593 % | NEOS Investment Management, LLC | 41 244 | 14 041 | 30.6.2024 |
0,08552 % | AllianceBernstein L.P. | 41 050 | 16 950 | 30.6.2024 |
0,08333 % | SBI Okasan Asset Management Co., Ltd. | 40 000 | −20 021 | 31.3.2024 |
0,08324 % | UBS Asset Management (Switzerland) | 39 954 | 7 280 | 30.6.2024 |
0,08201 % | PDT Partners, LLC | 39 363 | 39 363 | 30.6.2024 |
0,07935 % | UBS O'Connor LLC | 38 088 | −11 769 | 30.6.2024 |
0,07833 % | Nomura Asset Management Co., Ltd. | 37 600 | 37 600 | 30.11.2023 |
0,07795 % | Legal & General Investment Management Ltd. | 37 418 | 8 773 | 30.6.2024 |
0,07658 % | Alps Advisors, Inc. | 36 759 | 3 876 | 30.6.2024 |
0,07607 % | Secure Asset Management, L.L.C. | 36 514 | −9 390 | 30.9.2024 |