18,39197 % | VenBio Partners LLC | 9 699 925 | 0 | 31.12.2024 |
6,99585 % | Redmile Group, LLC | 3 689 611 | −146 965 | 31.12.2024 |
6,49778 % | HBM Partners AG | 3 426 929 | 3 426 929 | 18.12.2024 |
6,25120 % | Tang Capital Management, LLC | 3 296 883 | −907 852 | 31.12.2024 |
5,59268 % | Lightstone Ventures, L.P. | 2 949 580 | −1 259 395 | 12.2.2024 |
4,25091 % | Morgan Stanley & Co. LLC | 2 241 932 | 1 996 515 | 31.12.2024 |
4,12101 % | BlackRock Institutional Trust Company, N.A. | 2 173 423 | −180 204 | 31.12.2024 |
4,03699 % | Millennium Management LLC | 2 129 110 | 126 736 | 31.12.2024 |
3,57793 % | The Vanguard Group, Inc. | 1 887 002 | 2 429 | 31.12.2024 |
3,17381 % | Fidelity Management & Research Company LLC | 1 673 866 | −4 188 215 | 31.12.2024 |
2,89729 % | Two Sigma Investments, LP | 1 528 031 | 367 472 | 31.12.2024 |
2,63829 % | MPM BioImpact LLC | 1 391 434 | −1 018 428 | 31.12.2024 |
2,31882 % | Almitas Capital LLC | 1 222 945 | 1 222 945 | 31.12.2024 |
2,10362 % | Acadian Asset Management LLC | 1 109 448 | 683 024 | 31.12.2024 |
1,96308 % | BofA Global Research (US) | 1 035 326 | 860 703 | 31.12.2024 |
1,40331 % | Geode Capital Management, L.L.C. | 740 106 | 39 259 | 31.12.2024 |
1,29716 % | State Street Global Advisors (US) | 684 123 | 12 747 | 31.12.2024 |
1,15542 % | BMO Capital Markets (US) | 609 368 | 609 368 | 31.12.2024 |
0,96522 % | Privium Fund Management BV | 509 059 | 0 | 31.12.2024 |
0,80885 % | Pons (Jaume) | 426 589 | −10 796 | 30.12.2024 |
0,77371 % | UBS Financial Services, Inc. | 408 056 | 378 816 | 31.12.2024 |
0,68354 % | Goldman Sachs & Company, Inc. | 360 498 | 208 278 | 31.12.2024 |
0,65040 % | Northern Trust Investments, Inc. | 343 020 | 63 853 | 31.12.2024 |
0,57152 % | Los Angeles Capital Management LLC | 301 419 | 43 640 | 31.12.2024 |
0,50030 % | XTX Markets LLC | 263 856 | −53 466 | 31.12.2024 |
0,48517 % | D. E. Shaw & Co., L.P. | 255 878 | −34 518 | 31.12.2024 |
0,47820 % | Parametric Portfolio Associates LLC | 252 201 | 182 066 | 31.12.2024 |
0,46044 % | Randolph (Sophia) | 242 836 | −1 365 | 14.8.2024 |
0,41186 % | BMO Family Office, LLC | 217 214 | 217 214 | 31.12.2024 |
0,41090 % | Charles Schwab Investment Management, Inc. | 216 707 | −8 595 | 31.12.2024 |
0,40782 % | J.P. Morgan Securities LLC | 215 085 | 194 983 | 31.12.2024 |
0,39536 % | Goldman Sachs Asset Management, L.P. | 208 511 | 126 656 | 31.12.2024 |
0,37482 % | Diadema Partners LP | 197 680 | 197 680 | 31.12.2024 |
0,33692 % | Fidelity Institutional Asset Management | 177 690 | 174 665 | 31.12.2024 |
0,31735 % | Goodman (Corey S) | 167 370 | 0 | 31.3.2024 |
0,28749 % | Susquehanna International Group, LLP | 151 620 | 121 272 | 31.12.2024 |
0,26255 % | Qube Research & Technologies Ltd | 138 470 | −319 247 | 31.12.2024 |
0,21886 % | BlackRock Financial Management, Inc. | 115 429 | −2 241 | 31.12.2024 |
0,20749 % | Lettmann (Jason) | 109 429 | −2 191 | 14.8.2024 |
0,19967 % | Bank of Nova Scotia | 105 306 | 105 306 | 31.12.2024 |
0,19718 % | Nuveen LLC | 103 995 | 0 | 31.12.2024 |
0,19013 % | DWS Investments UK Limited | 100 276 | 84 830 | 31.12.2024 |
0,17747 % | BlackRock Investment Management, LLC | 93 597 | 0 | 31.12.2024 |
0,14221 % | Bridgeway Capital Management, LLC | 75 000 | 75 000 | 31.12.2024 |
0,13601 % | AllianceBernstein L.P. | 71 730 | 0 | 31.12.2024 |
0,13145 % | BNY Mellon Asset Management | 69 327 | 9 623 | 31.12.2024 |
0,12554 % | abrdn Inc. | 66 211 | 0 | 31.12.2024 |
0,12348 % | Barclays Bank PLC | 65 122 | 5 620 | 31.12.2024 |
0,11527 % | SEI Investments Management Corporation | 60 795 | 7 525 | 31.12.2024 |
0,11527 % | Nuveen Asset Management, LLC | 60 795 | 58 896 | 31.12.2024 |
0,11377 % | Klencke (Barbara M.D.) | 60 000 | 60 000 | 21.1.2025 |
0,11098 % | LSV Asset Management | 58 530 | −1 620 | 31.1.2025 |
0,09229 % | Garcia (Peter S) | 48 673 | −761 | 14.8.2024 |
0,08164 % | Vanguard Personalized Indexing Management, LLC | 43 056 | 14 399 | 31.12.2024 |
0,08061 % | Rhumbline Advisers Ltd. Partnership | 42 516 | 405 | 31.12.2024 |
0,07961 % | AQR Capital Management, LLC | 41 985 | 13 479 | 31.12.2024 |
0,07954 % | Nan Fung Life Sciences | 41 950 | 0 | 31.12.2024 |
0,07774 % | Deka Investment GmbH | 41 000 | 16 700 | 31.12.2023 |
0,07774 % | Deka Vermögensmanagement GmbH | 41 000 | 0 | 31.12.2024 |
0,07034 % | Citadel Advisors LLC | 37 095 | 37 095 | 31.12.2024 |
0,06257 % | Hemrajani (Rekha) | 33 000 | 30 000 | 2.12.2024 |
0,06143 % | Pinto (Shelly) | 32 398 | −2 221 | 6.1.2025 |
0,06071 % | Cubist Systematic Strategies, LLC | 32 021 | −351 491 | 31.12.2024 |
0,06013 % | Wealth Enhancement Advisory Services, LLC | 31 710 | 0 | 31.12.2024 |
0,05961 % | Citi Investment Research (US) | 31 436 | 5 884 | 31.12.2024 |
0,05957 % | The Financial Advisory Group, Inc | 31 417 | 0 | 31.3.2024 |
0,05496 % | Avantis Investors | 28 985 | 8 467 | 31.3.2024 |
0,04974 % | Dimensional Fund Advisors, L.P. | 26 233 | −11 413 | 31.12.2024 |
0,04599 % | SG Americas Securities, L.L.C. | 24 256 | −3 138 | 31.12.2024 |
0,03944 % | Dimensional Fund Advisors, Ltd. | 20 801 | 0 | 30.11.2024 |
0,03920 % | Mellon Investments Corporation | 20 676 | 0 | 31.12.2024 |
0,03878 % | Jane Street Capital, L.L.C. | 20 454 | −7 464 | 31.12.2024 |
0,03586 % | Mirae Asset Global Investments (USA) LLC | 18 913 | −1 069 | 31.12.2024 |
0,03318 % | JSF Financial, LLC | 17 500 | 17 500 | 31.12.2024 |
0,03248 % | Corebridge Financial Inc. | 17 129 | −1 093 | 31.12.2024 |
0,03206 % | Commonwealth Financial Network | 16 909 | 1 069 | 31.12.2024 |
0,03063 % | HSBC Global Asset Management (UK) Limited | 16 154 | 2 235 | 31.12.2024 |
0,03053 % | Wells Fargo Bank, N.A. | 16 099 | 5 603 | 31.12.2024 |
0,03034 % | Abaris Investment Management AG | 16 000 | 8 000 | 31.12.2023 |
0,02934 % | HC Advisors, LLC | 15 475 | −300 | 31.12.2024 |
0,02881 % | Moneta Group Investment Advisors, LLC | 15 196 | 15 196 | 31.12.2024 |
0,02873 % | JPMorgan Private Bank (United States) | 15 150 | 353 | 31.12.2024 |
0,02865 % | Group One Trading, L.P. | 15 112 | −203 | 31.12.2024 |
0,02762 % | Simplex Trading, LLC | 14 567 | −2 579 | 31.12.2024 |
0,02507 % | Lido Advisors, LLC | 13 220 | 13 220 | 31.12.2024 |
0,02502 % | INTECH Investment Management LLC | 13 198 | 13 198 | 31.12.2024 |
0,02374 % | New York State Common Retirement Fund | 12 522 | 0 | 31.12.2024 |
0,02165 % | BNP Paribas Securities Corp. North America | 11 417 | 11 417 | 31.12.2024 |
0,02014 % | T. Rowe Price International Ltd | 10 622 | 0 | 31.12.2024 |
0,01973 % | Abel Hall, LLC | 10 406 | 10 406 | 31.12.2024 |
0,01533 % | ProShare Advisors LLC | 8 086 | −1 067 | 31.1.2025 |
0,01532 % | BlueStar Investment Managers SA | 8 080 | 0 | 30.11.2024 |
0,01328 % | Florida State Board of Administration | 7 005 | 0 | 30.6.2024 |
0,01166 % | Police and Firemen's Retirement System of New Jersey | 6 148 | 6 148 | 31.12.2024 |
0,01120 % | Northern Trust Global Investments | 5 905 | −34 670 | 31.12.2024 |
0,01102 % | J.P. Morgan Securities plc | 5 811 | −199 | 31.12.2024 |
0,01085 % | Principal Global Investors (Equity) | 5 721 | 0 | 31.12.2024 |
0,01062 % | Mercer Global Investments Management Ltd | 5 603 | 0 | 30.4.2024 |
0,00948 % | Tower Research Capital LLC | 5 001 | −2 346 | 31.12.2024 |
0,00937 % | BlackRock Advisors, LLC | 4 942 | 0 | 31.8.2024 |